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The map label for this gene is rpiA [H]

Identifier: 17545951

GI number: 17545951

Start: 1303464

End: 1304150

Strand: Direct

Name: rpiA [H]

Synonym: RSc1232

Alternate gene names: 17545951

Gene position: 1303464-1304150 (Clockwise)

Preceding gene: 17545949

Following gene: 17545952

Centisome position: 35.07

GC content: 68.27

Gene sequence:

>687_bases
ATGACGCAGGATGAACTGAAGGCGCTGGTGGCCCAGGCCGCCGCCGACTACGTATTGGCCAACGTGCCCGAGGGCGCCGT
GCTGGGTGTCGGCACCGGTTCGACCGCCAACCTGTTCATCGACGCGATGGCGCCGCACAAGGCGCGCTTCGCCGGCGCGG
TGTCGAGCTCGGAGGCGTCGACGCGCCGTCTGCAGGGCCACGGTTTTGCCGTGCTGGATCTGAACGAGGTCGATACGATT
CCCGTCTACGTGGACGGTGCCGACGAGATCGATGACACGGGCGCCATGATCAAGGGCGGCGGCGGCGCGCTGACGCGCGA
GAAGATCGTCGCGTCGGTGGCAGGACGGTTCGTCTGCATCGCCGACGGCAGCAAGCTGGTCGATGTGCTCGGCGCTTTCC
CGCTGCCGGTGGAAGTGGTGCCGATGGCACGCGCCGCAGTAGCGCGCCAGCTGGCGGCGCTGGGCGGCCAGCCGCGCCTG
CGCATGACCAAGGAAGGCCAGATCTACCAGACCGACAACGGCAATGTGATCCTGGATGTCTCCGGCCTGCGGATCGGCGA
GCCGAAGACGCTCGAGGCGCAGATCAACGATATTCCCGGCGTGGTGACGGTCGGCCTGTTCGCCAAGCGCGGCGCCGATG
TGCTGCTGCTGGGCACCGAAGCGGGCGTGCAGCGCCGCGACTTCTGA

Upstream 100 bases:

>100_bases
ATCGATTGTACTCCGCGCCTCCGGCGCCGCTGTACTGCGGCGGACCGTCGCGGTGATCCGGTACACTACCGGGTTTTCCG
ATTCCGACCGAGTTTTCGCG

Downstream 100 bases:

>100_bases
TCCGCAGCACGCGCCGCGTTTTTCGCGCGGCGCCACCCGCGAAGATGCCGTTCCAGCGCAGGGCTGAACGGCATTTTTCT
TTTGCGCAGGCGATGTCATG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTQDELKALVAQAAADYVLANVPEGAVLGVGTGSTANLFIDAMAPHKARFAGAVSSSEASTRRLQGHGFAVLDLNEVDTI
PVYVDGADEIDDTGAMIKGGGGALTREKIVASVAGRFVCIADGSKLVDVLGAFPLPVEVVPMARAAVARQLAALGGQPRL
RMTKEGQIYQTDNGNVILDVSGLRIGEPKTLEAQINDIPGVVTVGLFAKRGADVLLLGTEAGVQRRDF

Sequences:

>Translated_228_residues
MTQDELKALVAQAAADYVLANVPEGAVLGVGTGSTANLFIDAMAPHKARFAGAVSSSEASTRRLQGHGFAVLDLNEVDTI
PVYVDGADEIDDTGAMIKGGGGALTREKIVASVAGRFVCIADGSKLVDVLGAFPLPVEVVPMARAAVARQLAALGGQPRL
RMTKEGQIYQTDNGNVILDVSGLRIGEPKTLEAQINDIPGVVTVGLFAKRGADVLLLGTEAGVQRRDF
>Mature_227_residues
TQDELKALVAQAAADYVLANVPEGAVLGVGTGSTANLFIDAMAPHKARFAGAVSSSEASTRRLQGHGFAVLDLNEVDTIP
VYVDGADEIDDTGAMIKGGGGALTREKIVASVAGRFVCIADGSKLVDVLGAFPLPVEVVPMARAAVARQLAALGGQPRLR
MTKEGQIYQTDNGNVILDVSGLRIGEPKTLEAQINDIPGVVTVGLFAKRGADVLLLGTEAGVQRRDF

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=234, Percent_Identity=36.7521367521368, Blast_Score=106, Evalue=1e-23,
Organism=Escherichia coli, GI1789280, Length=224, Percent_Identity=62.5, Blast_Score=259, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17551758, Length=204, Percent_Identity=36.7647058823529, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324669, Length=214, Percent_Identity=27.1028037383178, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281364072, Length=194, Percent_Identity=36.5979381443299, Blast_Score=94, Evalue=6e-20,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23637; Mature: 23506

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDELKALVAQAAADYVLANVPEGAVLGVGTGSTANLFIDAMAPHKARFAGAVSSSEAS
CCHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCEEEEEECCCCCHHHHCCCCCCCCH
TRRLQGHGFAVLDLNEVDTIPVYVDGADEIDDTGAMIKGGGGALTREKIVASVAGRFVCI
HHEECCCCEEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCEEEE
ADGSKLVDVLGAFPLPVEVVPMARAAVARQLAALGGQPRLRMTKEGQIYQTDNGNVILDV
ECCCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCEEEEE
SGLRIGEPKTLEAQINDIPGVVTVGLFAKRGADVLLLGTEAGVQRRDF
CCEEECCCCEEEEEECCCCCEEEEEHHHCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TQDELKALVAQAAADYVLANVPEGAVLGVGTGSTANLFIDAMAPHKARFAGAVSSSEAS
CHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCEEEEEECCCCCHHHHCCCCCCCCH
TRRLQGHGFAVLDLNEVDTIPVYVDGADEIDDTGAMIKGGGGALTREKIVASVAGRFVCI
HHEECCCCEEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCEEEE
ADGSKLVDVLGAFPLPVEVVPMARAAVARQLAALGGQPRLRMTKEGQIYQTDNGNVILDV
ECCCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCEEEEE
SGLRIGEPKTLEAQINDIPGVVTVGLFAKRGADVLLLGTEAGVQRRDF
CCEEECCCCEEEEEECCCCCEEEEEHHHCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA