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The map label for this gene is zraR [H]

Identifier: 17545905

GI number: 17545905

Start: 1249454

End: 1250830

Strand: Reverse

Name: zraR [H]

Synonym: RSc1186

Alternate gene names: 17545905

Gene position: 1250830-1249454 (Counterclockwise)

Preceding gene: 17545906

Following gene: 17545904

Centisome position: 33.66

GC content: 67.76

Gene sequence:

>1377_bases
ATGCGCGAAGAGCCGCTGGAATGTACAAGTGCGTGCCGAACCGTTGTGGTTGCGTCACGCACCGGCATGGGGGAGATCAG
CGAGACGATCCTGGGCGCGGATTGGCATGTCAGGCACGTCAACTCGGTGCGCGAACTCGGATGCGCCATCCGTGACGGCG
TGCCGAAAGCCGGGCTGATCGACTTCGGCAGCGCGTTCTCGTCCGCTGAGCTGGATCTGCTCGAGCGCTGCCTGCAGGTT
TCGCACGTGGGCTGGGTGGCCGCGCTGCCGCAGGCCATGCTGAGCCATGAGCGCGTACGCCAATTGGTGCGCGACTATTG
CGTCGACTACGTCCAGATGCCGCTGCGCATCGAGGAAGCCGGGTACTCGCTGCGGCATGCATGGGGCATGGCCACGCTGG
CGCAGGAGGCCCCCGCGCCCAAGATCAGCAATGCCCGCATGCTCGGCGAATGTTCAGCCATGCAGAGCCTGTTCCGGGCG
ATCCGCAAGGTCGCGCAGAACAGCGCGCCCGCCTTCATCGCCGGCGAATCGGGCACCGGCAAGGAACTGACGGCCCAGGC
CATCCACGAGGCCTCGGCGCGCGCGGGCGGTCCCTTCATCGCCATCAACTGCGGCGCCATCCCGCCGCACCTGATCCAGT
CCGAGCTGTTCGGCTACGAGAAAGGCGCCTTCACCGGCGCGCACCAGCGCCATATCGGCTGGGTCGAGCACGCCAACGGC
GGCACGCTGTTCCTCGATGAGATCGGCGACCTGCCGCTGGAGAGCCAGGTGAGCCTGCTGCGCTTCCTGCAGCAAGGCAC
CATCACGCGGCTGGGCGGGCACCAGGCGATTCCGCTCGACCTGCGCATCATCTCCGCCACGCACGTGGACCTGGAGGCCG
CGCAGCATCACGGCGGCTTCCGCACCGACCTGTTCCACCGGCTGTGCGTGCTGACGCTGTCGGTGCCGCCGCTGCGCGAG
CGCGGCAGCGATATCGTGCTGCTGGCCGAGCATATCCTGGCCCAGCACGCCAACGAGGCCTCGCACCGCATTCGCGGCTT
CACGCCCTGCGCGCTGCACGCGATGATGCACTACCCGTGGCCGGGCAACGTGCGCGAGCTGATCAACCGCGTCCGCCGCG
CGCTGGTGATGACGGACAACCGCAAGATCTCCGCCTCCGACCTGCACCTGGAAGGCTACGCATCGATCTCCGGCCAGACG
CTGGAAGAAGCGCGCGAAGGCGCGGAATCCGATGCGATCCGCACCGCCATCGCCCGCAACGGCTTCCATATGGGCATGAC
GGCGCGCGAGCTGGCGGTGTCCCGCGTGACGCTGTACCGGCTGATGCAGAAGCACGGCATCCGCGCCGAACACCCCCTGC
ATCATCCGGTTTCGTAG

Upstream 100 bases:

>100_bases
GTCCTTAAACGTCATCGCAAAAGCGCAGCGCGAGAACCATACTGCAAGCCTGCTTGAGCCAAGCAGCAGGGAAACCACGA
AAAATCGAACGGGGGAAACC

Downstream 100 bases:

>100_bases
CCGTCGGGCCGACGGCGGCCAGGCCATCGGGGCGCGGCGCATGTCGCGCCCTGTTCGTTGCGCCGCCACACATGAAAAAA
AGAGTGCCCGCCGGGGGACG

Product: sigma-54 interacting transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MREEPLECTSACRTVVVASRTGMGEISETILGADWHVRHVNSVRELGCAIRDGVPKAGLIDFGSAFSSAELDLLERCLQV
SHVGWVAALPQAMLSHERVRQLVRDYCVDYVQMPLRIEEAGYSLRHAWGMATLAQEAPAPKISNARMLGECSAMQSLFRA
IRKVAQNSAPAFIAGESGTGKELTAQAIHEASARAGGPFIAINCGAIPPHLIQSELFGYEKGAFTGAHQRHIGWVEHANG
GTLFLDEIGDLPLESQVSLLRFLQQGTITRLGGHQAIPLDLRIISATHVDLEAAQHHGGFRTDLFHRLCVLTLSVPPLRE
RGSDIVLLAEHILAQHANEASHRIRGFTPCALHAMMHYPWPGNVRELINRVRRALVMTDNRKISASDLHLEGYASISGQT
LEEAREGAESDAIRTAIARNGFHMGMTARELAVSRVTLYRLMQKHGIRAEHPLHHPVS

Sequences:

>Translated_458_residues
MREEPLECTSACRTVVVASRTGMGEISETILGADWHVRHVNSVRELGCAIRDGVPKAGLIDFGSAFSSAELDLLERCLQV
SHVGWVAALPQAMLSHERVRQLVRDYCVDYVQMPLRIEEAGYSLRHAWGMATLAQEAPAPKISNARMLGECSAMQSLFRA
IRKVAQNSAPAFIAGESGTGKELTAQAIHEASARAGGPFIAINCGAIPPHLIQSELFGYEKGAFTGAHQRHIGWVEHANG
GTLFLDEIGDLPLESQVSLLRFLQQGTITRLGGHQAIPLDLRIISATHVDLEAAQHHGGFRTDLFHRLCVLTLSVPPLRE
RGSDIVLLAEHILAQHANEASHRIRGFTPCALHAMMHYPWPGNVRELINRVRRALVMTDNRKISASDLHLEGYASISGQT
LEEAREGAESDAIRTAIARNGFHMGMTARELAVSRVTLYRLMQKHGIRAEHPLHHPVS
>Mature_458_residues
MREEPLECTSACRTVVVASRTGMGEISETILGADWHVRHVNSVRELGCAIRDGVPKAGLIDFGSAFSSAELDLLERCLQV
SHVGWVAALPQAMLSHERVRQLVRDYCVDYVQMPLRIEEAGYSLRHAWGMATLAQEAPAPKISNARMLGECSAMQSLFRA
IRKVAQNSAPAFIAGESGTGKELTAQAIHEASARAGGPFIAINCGAIPPHLIQSELFGYEKGAFTGAHQRHIGWVEHANG
GTLFLDEIGDLPLESQVSLLRFLQQGTITRLGGHQAIPLDLRIISATHVDLEAAQHHGGFRTDLFHRLCVLTLSVPPLRE
RGSDIVLLAEHILAQHANEASHRIRGFTPCALHAMMHYPWPGNVRELINRVRRALVMTDNRKISASDLHLEGYASISGQT
LEEAREGAESDAIRTAIARNGFHMGMTARELAVSRVTLYRLMQKHGIRAEHPLHHPVS

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=338, Percent_Identity=42.8994082840237, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1788550, Length=356, Percent_Identity=40.1685393258427, Blast_Score=251, Evalue=9e-68,
Organism=Escherichia coli, GI1790299, Length=388, Percent_Identity=38.659793814433, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1788905, Length=298, Percent_Identity=43.9597315436242, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI87082117, Length=327, Percent_Identity=41.5902140672783, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI87082152, Length=333, Percent_Identity=40.5405405405405, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1786524, Length=320, Percent_Identity=41.875, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1789233, Length=322, Percent_Identity=40.6832298136646, Blast_Score=215, Evalue=4e-57,
Organism=Escherichia coli, GI87081872, Length=318, Percent_Identity=36.1635220125786, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1789087, Length=307, Percent_Identity=39.413680781759, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787583, Length=332, Percent_Identity=34.9397590361446, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI87081858, Length=295, Percent_Identity=34.2372881355932, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1789828, Length=234, Percent_Identity=34.1880341880342, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50234; Mature: 50234

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREEPLECTSACRTVVVASRTGMGEISETILGADWHVRHVNSVRELGCAIRDGVPKAGLI
CCCCCCHHHHHHHEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DFGSAFSSAELDLLERCLQVSHVGWVAALPQAMLSHERVRQLVRDYCVDYVQMPLRIEEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHC
GYSLRHAWGMATLAQEAPAPKISNARMLGECSAMQSLFRAIRKVAQNSAPAFIAGESGTG
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
KELTAQAIHEASARAGGPFIAINCGAIPPHLIQSELFGYEKGAFTGAHQRHIGWVEHANG
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCEEECCC
GTLFLDEIGDLPLESQVSLLRFLQQGTITRLGGHQAIPLDLRIISATHVDLEAAQHHGGF
CEEEEECCCCCCCHHHHHHHHHHHHCCEEECCCCEECCEEEEEEEEEHHHHHHHHHCCCC
RTDLFHRLCVLTLSVPPLRERGSDIVLLAEHILAQHANEASHRIRGFTPCALHAMMHYPW
HHHHHHHHHHHHCCCCCHHHCCCCEEEHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCC
PGNVRELINRVRRALVMTDNRKISASDLHLEGYASISGQTLEEAREGAESDAIRTAIARN
CCCHHHHHHHHHHHHEECCCCEECCCCEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHC
GFHMGMTARELAVSRVTLYRLMQKHGIRAEHPLHHPVS
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MREEPLECTSACRTVVVASRTGMGEISETILGADWHVRHVNSVRELGCAIRDGVPKAGLI
CCCCCCHHHHHHHEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DFGSAFSSAELDLLERCLQVSHVGWVAALPQAMLSHERVRQLVRDYCVDYVQMPLRIEEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHC
GYSLRHAWGMATLAQEAPAPKISNARMLGECSAMQSLFRAIRKVAQNSAPAFIAGESGTG
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
KELTAQAIHEASARAGGPFIAINCGAIPPHLIQSELFGYEKGAFTGAHQRHIGWVEHANG
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCEEECCC
GTLFLDEIGDLPLESQVSLLRFLQQGTITRLGGHQAIPLDLRIISATHVDLEAAQHHGGF
CEEEEECCCCCCCHHHHHHHHHHHHCCEEECCCCEECCEEEEEEEEEHHHHHHHHHCCCC
RTDLFHRLCVLTLSVPPLRERGSDIVLLAEHILAQHANEASHRIRGFTPCALHAMMHYPW
HHHHHHHHHHHHCCCCCHHHCCCCEEEHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCC
PGNVRELINRVRRALVMTDNRKISASDLHLEGYASISGQTLEEAREGAESDAIRTAIARN
CCCHHHHHHHHHHHHEECCCCEECCCCEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHC
GFHMGMTARELAVSRVTLYRLMQKHGIRAEHPLHHPVS
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]