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The map label for this gene is rho [H]

Identifier: 17545906

GI number: 17545906

Start: 1251086

End: 1252348

Strand: Reverse

Name: rho [H]

Synonym: RSc1187

Alternate gene names: 17545906

Gene position: 1252348-1251086 (Counterclockwise)

Preceding gene: 17545907

Following gene: 17545905

Centisome position: 33.7

GC content: 62.15

Gene sequence:

>1263_bases
ATGCATCTGACAGAACTGAAATCCCTGCATGTGTCCCAATTGCTGGAAATGGCGGGACAGCTGGAGATCGACAACGCGCA
GCGCATGCGCAAACAGGAGCTGATGTTTGCCATCCTGAAAAAGAAAGCGAAACAGGGGGAAACGATTTTCGGCGACGGCA
CGCTGGAAGTGCTGCCCGACGGCTTCGGCTTTCTGCGCTCGCCGGAAACGTCGTACCTGGCGAGCACGGACGACATCTAC
ATCAGCCCGTCGCAGATCCGCCGCTTCAACCTGCACACCGGCGACACCATCGAAGGCGAAGTCCGCACGCCCAAGGACGG
CGAGCGTTACTTCGCGCTGGTGAAGGTCGACAAGGTCAACGCCCAGCCTCCTGAAGCGGTCAAGAACCGCATCATGTTCG
AGAACCTGACGCCGCTGCATCCGAACCGCACGCTCACGCTCGAACGCGACATCAAGGCCGAGGAGAACATCACCGGCCGC
ATCATCGACATGATCGCCCCGATCGGCCGCGGCCAGCGCGCGCTGCTGGTGGCCTCGCCCAAGTCGGGCAAGACCGTGAT
GCTGCAGCACATCGCGCATGCCATCACGGCCAACCATCCGGAAGCCGAACTGTTCGTGCTGCTGATCGACGAGCGTCCGG
AAGAAGTGACCGAGATGCAGCGCACCGTGCGCGGCGAAGTGGTGGCCTCCACCTTCGACGAGCCGGCCGTGCGCCACGTG
CAGGTCGCGGAAATGGTGATCGAGAAGGCCAAGCGCCTGGTTGAACTGAAGAAGGACGTGGTGATCGTGCTGGACTCGAT
CACGCGCCTGGCCCGCGCCTACAACACCGTGGTGCCGACCTCCGGCAAGGTGCTGACCGGCGGCGTGGACGCCAACGCCC
TGCAGCGTCCGAAGCGCTTCTTCGGTGCCGCGCGCAATCTGGAGGAAGGCGGTTCGCTGACCATCATCGGCACGGCGCTG
ATCGAAACCGGCAGCCGCATGGACGACGTGATCTACGAAGAATTCAAGGGCACCGGCAACATGGAAGTGCACCTGGAGCG
CCGCCTGGCCGAGAAGCGCGTCTACCCCGCCATCAACCTGAACAAGTCGGGCACGCGCCGCGAAGAGCTGCTGATCAAGC
CGGACATCCTGCAGAAGGTGTGGATCCTGCGCAAGTTCATCCACGATATGGACGAGGTCGAGGCGATGGAATTCCTGCTC
GACAAGCTCAAGTCCACGAAGAACAACGCGGAGTTCTTCGACATGATGCGACGTGGCAGCTGA

Upstream 100 bases:

>100_bases
ATTGCAGCCAATCTGTTTCCCCGAGCGTTCGCTCGACCTTCCCCCTCCCCGCTTCATCCCGTATTCGCTGCCCGTCCGGG
CTCTTCCCATTCATTCGTCT

Downstream 100 bases:

>100_bases
GTCTGCGCGCCGCGTACCGGGAAGCGCACCTCTGGGTGCGCTTTTTTATTGCCCGCGCGCCGGCCGCGCATCCCCCACCG
GCATCGTTGGCGGCGTCATG

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MHLTELKSLHVSQLLEMAGQLEIDNAQRMRKQELMFAILKKKAKQGETIFGDGTLEVLPDGFGFLRSPETSYLASTDDIY
ISPSQIRRFNLHTGDTIEGEVRTPKDGERYFALVKVDKVNAQPPEAVKNRIMFENLTPLHPNRTLTLERDIKAEENITGR
IIDMIAPIGRGQRALLVASPKSGKTVMLQHIAHAITANHPEAELFVLLIDERPEEVTEMQRTVRGEVVASTFDEPAVRHV
QVAEMVIEKAKRLVELKKDVVIVLDSITRLARAYNTVVPTSGKVLTGGVDANALQRPKRFFGAARNLEEGGSLTIIGTAL
IETGSRMDDVIYEEFKGTGNMEVHLERRLAEKRVYPAINLNKSGTRREELLIKPDILQKVWILRKFIHDMDEVEAMEFLL
DKLKSTKNNAEFFDMMRRGS

Sequences:

>Translated_420_residues
MHLTELKSLHVSQLLEMAGQLEIDNAQRMRKQELMFAILKKKAKQGETIFGDGTLEVLPDGFGFLRSPETSYLASTDDIY
ISPSQIRRFNLHTGDTIEGEVRTPKDGERYFALVKVDKVNAQPPEAVKNRIMFENLTPLHPNRTLTLERDIKAEENITGR
IIDMIAPIGRGQRALLVASPKSGKTVMLQHIAHAITANHPEAELFVLLIDERPEEVTEMQRTVRGEVVASTFDEPAVRHV
QVAEMVIEKAKRLVELKKDVVIVLDSITRLARAYNTVVPTSGKVLTGGVDANALQRPKRFFGAARNLEEGGSLTIIGTAL
IETGSRMDDVIYEEFKGTGNMEVHLERRLAEKRVYPAINLNKSGTRREELLIKPDILQKVWILRKFIHDMDEVEAMEFLL
DKLKSTKNNAEFFDMMRRGS
>Mature_420_residues
MHLTELKSLHVSQLLEMAGQLEIDNAQRMRKQELMFAILKKKAKQGETIFGDGTLEVLPDGFGFLRSPETSYLASTDDIY
ISPSQIRRFNLHTGDTIEGEVRTPKDGERYFALVKVDKVNAQPPEAVKNRIMFENLTPLHPNRTLTLERDIKAEENITGR
IIDMIAPIGRGQRALLVASPKSGKTVMLQHIAHAITANHPEAELFVLLIDERPEEVTEMQRTVRGEVVASTFDEPAVRHV
QVAEMVIEKAKRLVELKKDVVIVLDSITRLARAYNTVVPTSGKVLTGGVDANALQRPKRFFGAARNLEEGGSLTIIGTAL
IETGSRMDDVIYEEFKGTGNMEVHLERRLAEKRVYPAINLNKSGTRREELLIKPDILQKVWILRKFIHDMDEVEAMEFLL
DKLKSTKNNAEFFDMMRRGS

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=418, Percent_Identity=70.0956937799043, Blast_Score=615, Evalue=1e-177,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 47422; Mature: 47422

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLTELKSLHVSQLLEMAGQLEIDNAQRMRKQELMFAILKKKAKQGETIFGDGTLEVLPD
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEECCC
GFGFLRSPETSYLASTDDIYISPSQIRRFNLHTGDTIEGEVRTPKDGERYFALVKVDKVN
CCCCCCCCCCCEEECCCCEEECHHHHEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCC
AQPPEAVKNRIMFENLTPLHPNRTLTLERDIKAEENITGRIIDMIAPIGRGQRALLVASP
CCCHHHHHHCEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEEEECC
KSGKTVMLQHIAHAITANHPEAELFVLLIDERPEEVTEMQRTVRGEVVASTFDEPAVRHV
CCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
QVAEMVIEKAKRLVELKKDVVIVLDSITRLARAYNTVVPTSGKVLTGGVDANALQRPKRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHH
FGAARNLEEGGSLTIIGTALIETGSRMDDVIYEEFKGTGNMEVHLERRLAEKRVYPAINL
HHHHCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCEEC
NKSGTRREELLIKPDILQKVWILRKFIHDMDEVEAMEFLLDKLKSTKNNAEFFDMMRRGS
CCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MHLTELKSLHVSQLLEMAGQLEIDNAQRMRKQELMFAILKKKAKQGETIFGDGTLEVLPD
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEECCC
GFGFLRSPETSYLASTDDIYISPSQIRRFNLHTGDTIEGEVRTPKDGERYFALVKVDKVN
CCCCCCCCCCCEEECCCCEEECHHHHEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCC
AQPPEAVKNRIMFENLTPLHPNRTLTLERDIKAEENITGRIIDMIAPIGRGQRALLVASP
CCCHHHHHHCEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEEEECC
KSGKTVMLQHIAHAITANHPEAELFVLLIDERPEEVTEMQRTVRGEVVASTFDEPAVRHV
CCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
QVAEMVIEKAKRLVELKKDVVIVLDSITRLARAYNTVVPTSGKVLTGGVDANALQRPKRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHH
FGAARNLEEGGSLTIIGTALIETGSRMDDVIYEEFKGTGNMEVHLERRLAEKRVYPAINL
HHHHCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCEEC
NKSGTRREELLIKPDILQKVWILRKFIHDMDEVEAMEFLLDKLKSTKNNAEFFDMMRRGS
CCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]