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The map label for this gene is aroG2 [H]

Identifier: 17545462

GI number: 17545462

Start: 788720

End: 789898

Strand: Direct

Name: aroG2 [H]

Synonym: RSc0743

Alternate gene names: 17545462

Gene position: 788720-789898 (Clockwise)

Preceding gene: 161621734

Following gene: 17545464

Centisome position: 21.22

GC content: 66.33

Gene sequence:

>1179_bases
ATGGGCAATCGGCGGACTGCCCCGGTTTCGGCGCACCGCTCGTGTTTCCAGGAGTTTTCCGTGATTCGCATCGACAATCC
CCAAAGCGACCAAGAAGTCGGCGTGGCCGACGCTACCCAGGACACCACCCGCATCGATGACGTGCGCATCGGTGCGGTCC
GTCCGCTCATTTCCCCGGCACTCCTGCTCGACGAGTTGCCCGTGTCGCCCGCCGTGCAGGCGCACGTCGAAGCGAGCCGG
GCCGCGGTCACGGACATCCTGCACGGACGGGACGATCGCCTGCTTGCCGTGGTGGGCCCGTGCTCGATCCACGATCACGA
CCAGGCGCTCGACTACGCCCATCGGCTCGGGACGGCCGCGAATCGCCTGCGCGACGATCTGCTGATCGTCATGCGCGTGT
ATTTCGAAAAGCCGCGCACGACCGTCGGCTGGAAGGGCTACATCAACGATCCGCGGCTCGACGGCAGCTTCCGCATCAAC
GAAGGGCTGCGCCGTGCGCGCCAGTTGCTCCTGGAAGTCAACGCGATGGGATTGCCGGCGGCCACCGAGTTTCTCGATCT
GCTGAGTCCGCAGTACATCGCGGACCTGATTGCCTGGGGCGCGATCGGCGCCAGGACGACGGAAAGCCAGAGCCATCGGC
AGCTCGCCTCGGGACTGAGCTGTCCCATCGGCTTCAAGAACGGCACGGATGGCGGTGTCCAGATCGCGGCGGACGCGATT
CTGGCGGCGCGGTCGAGCCACTCGTTCATGGGCATGACGAAGATGGGGATGGCCGCGATTTTCGAGACGCGCGGCAACGG
TGATGCGCACGTCATTCTTCGCGGCGGCAAGAAGGGACCGAACTATGACGCGGCGGCCATCGAAGACAGCTGCGCGATTC
TCCGGGCGGCCGGGCTGCGCGAGCAGGTGATGGTCGACTGTTCGCACGCGAACTCGGGCAAGTCCCATGCCCGTCAAGCC
GACGTTGCGCGGGATCTGGCGCAGCAGCTGTCGTCCGGCGAGCGGCGCATCAGCGGCGTGATGATCGAGAGCCATCTGGA
AGAGGGGCGCCAGGATCTGAAACCCGGCGTGCCGTTGCAGCGCGGCGTGTCCATTACCGATGCCTGCCTTGGGTGGTCCC
AGACGGAACCGTTGCTGGAAACCCTCGCAACGGCTGTGCGTGCGCGGCGGCGCGGCTAG

Upstream 100 bases:

>100_bases
AAGTCCGCCTTCAGTCTGCGCATCCGAAACCCGAGCTCGACTCACTACAATACCCGCCTGCGCTGCCATCCGCCGCTCGC
CCCGCCGATTTCCGCCGTCA

Downstream 100 bases:

>100_bases
CGGGGACTCGCGTCGAGGGGGATCACCATGCTGGTTTGGCGCCTAGCATGTGTCGCTGGCGATGAGATGTCCGGCGATCT
GAAGTGCGCCGATTGGCATC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MGNRRTAPVSAHRSCFQEFSVIRIDNPQSDQEVGVADATQDTTRIDDVRIGAVRPLISPALLLDELPVSPAVQAHVEASR
AAVTDILHGRDDRLLAVVGPCSIHDHDQALDYAHRLGTAANRLRDDLLIVMRVYFEKPRTTVGWKGYINDPRLDGSFRIN
EGLRRARQLLLEVNAMGLPAATEFLDLLSPQYIADLIAWGAIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQIAADAI
LAARSSHSFMGMTKMGMAAIFETRGNGDAHVILRGGKKGPNYDAAAIEDSCAILRAAGLREQVMVDCSHANSGKSHARQA
DVARDLAQQLSSGERRISGVMIESHLEEGRQDLKPGVPLQRGVSITDACLGWSQTEPLLETLATAVRARRRG

Sequences:

>Translated_392_residues
MGNRRTAPVSAHRSCFQEFSVIRIDNPQSDQEVGVADATQDTTRIDDVRIGAVRPLISPALLLDELPVSPAVQAHVEASR
AAVTDILHGRDDRLLAVVGPCSIHDHDQALDYAHRLGTAANRLRDDLLIVMRVYFEKPRTTVGWKGYINDPRLDGSFRIN
EGLRRARQLLLEVNAMGLPAATEFLDLLSPQYIADLIAWGAIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQIAADAI
LAARSSHSFMGMTKMGMAAIFETRGNGDAHVILRGGKKGPNYDAAAIEDSCAILRAAGLREQVMVDCSHANSGKSHARQA
DVARDLAQQLSSGERRISGVMIESHLEEGRQDLKPGVPLQRGVSITDACLGWSQTEPLLETLATAVRARRRG
>Mature_391_residues
GNRRTAPVSAHRSCFQEFSVIRIDNPQSDQEVGVADATQDTTRIDDVRIGAVRPLISPALLLDELPVSPAVQAHVEASRA
AVTDILHGRDDRLLAVVGPCSIHDHDQALDYAHRLGTAANRLRDDLLIVMRVYFEKPRTTVGWKGYINDPRLDGSFRINE
GLRRARQLLLEVNAMGLPAATEFLDLLSPQYIADLIAWGAIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQIAADAIL
AARSSHSFMGMTKMGMAAIFETRGNGDAHVILRGGKKGPNYDAAAIEDSCAILRAAGLREQVMVDCSHANSGKSHARQAD
VARDLAQQLSSGERRISGVMIESHLEEGRQDLKPGVPLQRGVSITDACLGWSQTEPLLETLATAVRARRRG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=58.5507246376812, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1787996, Length=346, Percent_Identity=54.0462427745665, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1788953, Length=339, Percent_Identity=51.622418879056, Blast_Score=352, Evalue=2e-98,
Organism=Saccharomyces cerevisiae, GI6320240, Length=362, Percent_Identity=51.1049723756906, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6319726, Length=352, Percent_Identity=52.8409090909091, Blast_Score=367, Evalue=1e-102,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 42387; Mature: 42255

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRRTAPVSAHRSCFQEFSVIRIDNPQSDQEVGVADATQDTTRIDDVRIGAVRPLISPA
CCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHCCEEECHHHHHHHHH
LLLDELPVSPAVQAHVEASRAAVTDILHGRDDRLLAVVGPCSIHDHDQALDYAHRLGTAA
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
NRLRDDLLIVMRVYFEKPRTTVGWKGYINDPRLDGSFRINEGLRRARQLLLEVNAMGLPA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCH
ATEFLDLLSPQYIADLIAWGAIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQIAADAI
HHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
LAARSSHSFMGMTKMGMAAIFETRGNGDAHVILRGGKKGPNYDAAAIEDSCAILRAAGLR
HHHCCCCCHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
EQVMVDCSHANSGKSHARQADVARDLAQQLSSGERRISGVMIESHLEEGRQDLKPGVPLQ
HHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
RGVSITDACLGWSQTEPLLETLATAVRARRRG
HCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GNRRTAPVSAHRSCFQEFSVIRIDNPQSDQEVGVADATQDTTRIDDVRIGAVRPLISPA
CCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHCCEEECHHHHHHHHH
LLLDELPVSPAVQAHVEASRAAVTDILHGRDDRLLAVVGPCSIHDHDQALDYAHRLGTAA
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
NRLRDDLLIVMRVYFEKPRTTVGWKGYINDPRLDGSFRINEGLRRARQLLLEVNAMGLPA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCH
ATEFLDLLSPQYIADLIAWGAIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQIAADAI
HHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
LAARSSHSFMGMTKMGMAAIFETRGNGDAHVILRGGKKGPNYDAAAIEDSCAILRAAGLR
HHHCCCCCHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
EQVMVDCSHANSGKSHARQADVARDLAQQLSSGERRISGVMIESHLEEGRQDLKPGVPLQ
HHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
RGVSITDACLGWSQTEPLLETLATAVRARRRG
HCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]