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The map label for this gene is tctD [H]

Identifier: 17545269

GI number: 17545269

Start: 595202

End: 595900

Strand: Reverse

Name: tctD [H]

Synonym: RSc0550

Alternate gene names: 17545269

Gene position: 595900-595202 (Counterclockwise)

Preceding gene: 17545279

Following gene: 17545268

Centisome position: 16.03

GC content: 70.82

Gene sequence:

>699_bases
ATGCGCATCCTGATTGCTGAAGACGACGCCACCCTGGCCGACGGGCTGACCCGTTCGTTGCGCCAGGCCGGCTATGCCGT
CGACCGGGCCGCGGACGGCGCCGCCGCCGACGCGGCCCTTTCCGCGCAGACCGCGCAAACCTACGACCTGCTGATCCTCG
ATGTCGGGCTGCCGCGCCTGTCCGGCCTGGAAGTGCTCAAGCGGCTGCGCTCGCGCGGGGCGATGCTGCCGGTGCTGATC
CTGACCGCCGCCGACAGCGTCGACGAGCGCGTCAAGGGCCTGGACCTGGGGGCCGACGACTACATGGCCAAGCCCTTTGC
GCTGTCCGAGCTGGAGGCGCGCGTGCGGGCGCTGGTGCGGCGCGGCACTGGCGGCGGCGCCACGCTGGTCCGCCACGGGC
CGCTGGCCTTCGACCAGGTCGGACGCATCGCCTACATCCGCGACCAGATGGTGGACCTGTCGGCGCGGGAGCTCGGGCTG
CTGGAGATCCTGCTGTCGCGCGCCGGCCGGCTGGTCTCGAAGGAACAGCTGGTCGACCACCTGTGCGGCTGGGGCGAAGA
AGTCAGCAACAACGCGATCGAGGTCTACGTGCACCGCCTGCGCAAGAAGATCGAGGTGGACGGCATCCGCATCGCCACCG
TGCGCGGGCTCGGCTATTGCCTGGAACGCGTGAGCGTACCGGCTGCCGTCCATGGGTGA

Upstream 100 bases:

>100_bases
AGTGGTTTTGACAAGTCTCCCGCTAGGACGTCGCGTGAAAAAATGTAGCGGGCGGGATGGACGGATCGGATGATCCGCCC
GGCATTGCGGGGAGACACGC

Downstream 100 bases:

>100_bases
CCGGCTGGCCTGGCCCTGGCGCCGGCCGCGCGCGGCGCCCGACCGCACCGCGCCGGGCGCCGACGACCACGATCTCGCCG
ACACCCTCCCCCACCTCGAG

Product: response regulator transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MRILIAEDDATLADGLTRSLRQAGYAVDRAADGAAADAALSAQTAQTYDLLILDVGLPRLSGLEVLKRLRSRGAMLPVLI
LTAADSVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGTGGGATLVRHGPLAFDQVGRIAYIRDQMVDLSARELGL
LEILLSRAGRLVSKEQLVDHLCGWGEEVSNNAIEVYVHRLRKKIEVDGIRIATVRGLGYCLERVSVPAAVHG

Sequences:

>Translated_232_residues
MRILIAEDDATLADGLTRSLRQAGYAVDRAADGAAADAALSAQTAQTYDLLILDVGLPRLSGLEVLKRLRSRGAMLPVLI
LTAADSVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGTGGGATLVRHGPLAFDQVGRIAYIRDQMVDLSARELGL
LEILLSRAGRLVSKEQLVDHLCGWGEEVSNNAIEVYVHRLRKKIEVDGIRIATVRGLGYCLERVSVPAAVHG
>Mature_232_residues
MRILIAEDDATLADGLTRSLRQAGYAVDRAADGAAADAALSAQTAQTYDLLILDVGLPRLSGLEVLKRLRSRGAMLPVLI
LTAADSVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGTGGGATLVRHGPLAFDQVGRIAYIRDQMVDLSARELGL
LEILLSRAGRLVSKEQLVDHLCGWGEEVSNNAIEVYVHRLRKKIEVDGIRIATVRGLGYCLERVSVPAAVHG

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=44.7963800904977, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=42.5339366515837, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=38.3928571428571, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=39.4736842105263, Blast_Score=143, Evalue=7e-36,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=38.3928571428571, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=35.5555555555556, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=33.4821428571429, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=32.6086956521739, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=31.981981981982, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=33.6283185840708, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=32.034632034632, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=31.4655172413793, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.004329004329, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788713, Length=118, Percent_Identity=39.8305084745763, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=35.1851851851852, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=25.2136752136752, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787487, Length=104, Percent_Identity=35.5769230769231, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790437, Length=111, Percent_Identity=36.036036036036, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788191, Length=124, Percent_Identity=31.4516129032258, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788550, Length=199, Percent_Identity=28.643216080402, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25020; Mature: 25020

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIAEDDATLADGLTRSLRQAGYAVDRAADGAAADAALSAQTAQTYDLLILDVGLPRL
CEEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCHHEEEEEEECCCCCC
SGLEVLKRLRSRGAMLPVLILTAADSVDERVKGLDLGADDYMAKPFALSELEARVRALVR
CHHHHHHHHHHCCCEEHHHEEECCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHH
RGTGGGATLVRHGPLAFDQVGRIAYIRDQMVDLSARELGLLEILLSRAGRLVSKEQLVDH
CCCCCCCEEEECCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LCGWGEEVSNNAIEVYVHRLRKKIEVDGIRIATVRGLGYCLERVSVPAAVHG
HHCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRILIAEDDATLADGLTRSLRQAGYAVDRAADGAAADAALSAQTAQTYDLLILDVGLPRL
CEEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCHHEEEEEEECCCCCC
SGLEVLKRLRSRGAMLPVLILTAADSVDERVKGLDLGADDYMAKPFALSELEARVRALVR
CHHHHHHHHHHCCCEEHHHEEECCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHH
RGTGGGATLVRHGPLAFDQVGRIAYIRDQMVDLSARELGLLEILLSRAGRLVSKEQLVDH
CCCCCCCEEEECCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LCGWGEEVSNNAIEVYVHRLRKKIEVDGIRIATVRGLGYCLERVSVPAAVHG
HHCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]