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The map label for this gene is qseC [H]

Identifier: 17545268

GI number: 17545268

Start: 593668

End: 595209

Strand: Reverse

Name: qseC [H]

Synonym: RSc0549

Alternate gene names: 17545268

Gene position: 595209-593668 (Counterclockwise)

Preceding gene: 17545269

Following gene: 17545267

Centisome position: 16.02

GC content: 70.56

Gene sequence:

>1542_bases
ATGGGTGACCGGCTGGCCTGGCCCTGGCGCCGGCCGCGCGCGGCGCCCGACCGCACCGCGCCGGGCGCCGACGACCACGA
TCTCGCCGACACCCTCCCCCACCTCGAGAACGACGCCACCCGGCCCATCGCCCGCTCACTGTTCGGCGAGATTCTCGACT
GGATGCTCGCGCCGCTGCTGCTGCTGTGGCCGATGAGCATTGCGGTGACCTACCTGGTGGCCAAGTCGATCGCCAATGCG
CCGTACGACCGCGCGCTGGAATCGAGCGCCATCGTGCTCAGCCAGCAATTGCACGAGGTCAACGGGCGCGTGACGTTGCA
GTTGCCGATCTCTGCGCGGGAGATTCTGCGCGCGGACGAGACCGACAACATCTATTACCAGGTGCTCGGCAGCAGCGGCG
AGTTCGTCTCCGGCGACCGCGATCTGCCGCTGCCCCCCGAGGAGGACGCCGGCGCCGGCAGCCTGGTGCAACTGCGCGAC
GACCGTATCCACGGTGCGGAGATCCGCGTGGCGTACACCTATGTGCAGCAGCCCGGCGCCCGGCCCGCGCTGGTGCAGGT
GGCCGAGACGCTGGACAAGCGCGCGCAGCTGGCCAACGAGATCATCAAGGGTGTGATCCTGCCGCAGTTCGTGATCCTGC
CGCTGGCGGTGATCCTGGTGTGGTTCGGGCTCACGCGCGGACTGGCGCCGCTCAACGCGATCCAGGAGCGCATCCGCGCG
CGCAGCCCGGGCGACACGAGCCCCATCGACGAAGGCGCGGCGCCGCAAGAGCTGACGCCCCTGGTCGCCTCATTCAACGA
GCTGCTCGGGCGCCTGGAGCAATCGGTGCAGACGCAGAAGCGCTTCATCGCCGATGCCGCGCACCAGATGAAGACGCCGC
TGGCCGGCCTGCGCATGCAGGCGGAGCTGGCGCAGCGCGAGCAGTCGCCCGACGAGCTGCGCCGCACCCTGGCTCACATC
GCCGACAGCTCGGAGCGCACCGCGCACCTGGTCAAGCAGCTGCTGTCGCTGGCGCGCATGGAGAACATGGGCGCGGCCGA
CGGCATGGTGCCGCTGGACCTGTGCGCGCTGTCGCGGCAGGTGGTAGCCGAGTGGCTGCCCAAGGCCTGGGCCAAGCAGA
TCGACCTGGGCTTCGAGGAGCCCGGCGCGCCGGTGACAACCTCCGGCAACGCCACCATGCTGGCCGAGATGCTCAACAAC
CTGCTCGACAACGCGATCCGCTACACGCCCGACGGCGGCCATGTCACGGTGCGCGTGACCACCGCGCCGTTCGAGCCCTT
CGTGTTCCTGGATGTGGAGGACACCGGCCCCGGCATTCCGGCGGGCGAGCGCGAGCGGGTCATGCAGCGCTTCTATCGCA
TCCTCGGCACGCAGGCCGAGGGCAGCGGACTGGGCCTGGCGATCGTGCGCGAGATCGTGCAGCAGCACGGCGGCGACATC
GCGGTGCTGGACTACGTCTACCAGTCGTCGCCGCGGCTGGCGGGGGCGCGGTTCCGCATCACCCTGCCGCACGGCACGCC
GGGCGAGGGGGCCTCGGCGTGA

Upstream 100 bases:

>100_bases
CACCGCCTGCGCAAGAAGATCGAGGTGGACGGCATCCGCATCGCCACCGTGCGCGGGCTCGGCTATTGCCTGGAACGCGT
GAGCGTACCGGCTGCCGTCC

Downstream 100 bases:

>100_bases
CGCCCGACGCCGCATCGGACGCACCGACGCCCGCGCGCTGGCGCTGGATCTCCAACATACGCTGGATCGCCGCGCTGCTG
GGCGTGTGGTTCGTGGTGAC

Product: transmembrane sensor histidine kinase transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MGDRLAWPWRRPRAAPDRTAPGADDHDLADTLPHLENDATRPIARSLFGEILDWMLAPLLLLWPMSIAVTYLVAKSIANA
PYDRALESSAIVLSQQLHEVNGRVTLQLPISAREILRADETDNIYYQVLGSSGEFVSGDRDLPLPPEEDAGAGSLVQLRD
DRIHGAEIRVAYTYVQQPGARPALVQVAETLDKRAQLANEIIKGVILPQFVILPLAVILVWFGLTRGLAPLNAIQERIRA
RSPGDTSPIDEGAAPQELTPLVASFNELLGRLEQSVQTQKRFIADAAHQMKTPLAGLRMQAELAQREQSPDELRRTLAHI
ADSSERTAHLVKQLLSLARMENMGAADGMVPLDLCALSRQVVAEWLPKAWAKQIDLGFEEPGAPVTTSGNATMLAEMLNN
LLDNAIRYTPDGGHVTVRVTTAPFEPFVFLDVEDTGPGIPAGERERVMQRFYRILGTQAEGSGLGLAIVREIVQQHGGDI
AVLDYVYQSSPRLAGARFRITLPHGTPGEGASA

Sequences:

>Translated_513_residues
MGDRLAWPWRRPRAAPDRTAPGADDHDLADTLPHLENDATRPIARSLFGEILDWMLAPLLLLWPMSIAVTYLVAKSIANA
PYDRALESSAIVLSQQLHEVNGRVTLQLPISAREILRADETDNIYYQVLGSSGEFVSGDRDLPLPPEEDAGAGSLVQLRD
DRIHGAEIRVAYTYVQQPGARPALVQVAETLDKRAQLANEIIKGVILPQFVILPLAVILVWFGLTRGLAPLNAIQERIRA
RSPGDTSPIDEGAAPQELTPLVASFNELLGRLEQSVQTQKRFIADAAHQMKTPLAGLRMQAELAQREQSPDELRRTLAHI
ADSSERTAHLVKQLLSLARMENMGAADGMVPLDLCALSRQVVAEWLPKAWAKQIDLGFEEPGAPVTTSGNATMLAEMLNN
LLDNAIRYTPDGGHVTVRVTTAPFEPFVFLDVEDTGPGIPAGERERVMQRFYRILGTQAEGSGLGLAIVREIVQQHGGDI
AVLDYVYQSSPRLAGARFRITLPHGTPGEGASA
>Mature_512_residues
GDRLAWPWRRPRAAPDRTAPGADDHDLADTLPHLENDATRPIARSLFGEILDWMLAPLLLLWPMSIAVTYLVAKSIANAP
YDRALESSAIVLSQQLHEVNGRVTLQLPISAREILRADETDNIYYQVLGSSGEFVSGDRDLPLPPEEDAGAGSLVQLRDD
RIHGAEIRVAYTYVQQPGARPALVQVAETLDKRAQLANEIIKGVILPQFVILPLAVILVWFGLTRGLAPLNAIQERIRAR
SPGDTSPIDEGAAPQELTPLVASFNELLGRLEQSVQTQKRFIADAAHQMKTPLAGLRMQAELAQREQSPDELRRTLAHIA
DSSERTAHLVKQLLSLARMENMGAADGMVPLDLCALSRQVVAEWLPKAWAKQIDLGFEEPGAPVTTSGNATMLAEMLNNL
LDNAIRYTPDGGHVTVRVTTAPFEPFVFLDVEDTGPGIPAGERERVMQRFYRILGTQAEGSGLGLAIVREIVQQHGGDIA
VLDYVYQSSPRLAGARFRITLPHGTPGEGASA

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=366, Percent_Identity=29.5081967213115, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1786783, Length=322, Percent_Identity=32.9192546583851, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790551, Length=302, Percent_Identity=28.8079470198675, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=30.1158301158301, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=29.5081967213115, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790346, Length=260, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788279, Length=332, Percent_Identity=26.8072289156627, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=30.6382978723404, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790861, Length=312, Percent_Identity=28.8461538461538, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=29.1666666666667, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=31.5126050420168, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787374, Length=305, Percent_Identity=25.2459016393443, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787894, Length=319, Percent_Identity=26.3322884012539, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082128, Length=311, Percent_Identity=26.3665594855305, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=29.4642857142857, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=24.7863247863248, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081816, Length=257, Percent_Identity=26.8482490272374, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789808, Length=288, Percent_Identity=25, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56014; Mature: 55882

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDRLAWPWRRPRAAPDRTAPGADDHDLADTLPHLENDATRPIARSLFGEILDWMLAPLL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LLWPMSIAVTYLVAKSIANAPYDRALESSAIVLSQQLHEVNGRVTLQLPISAREILRADE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCC
TDNIYYQVLGSSGEFVSGDRDLPLPPEEDAGAGSLVQLRDDRIHGAEIRVAYTYVQQPGA
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEEECCCCC
RPALVQVAETLDKRAQLANEIIKGVILPQFVILPLAVILVWFGLTRGLAPLNAIQERIRA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
RSPGDTSPIDEGAAPQELTPLVASFNELLGRLEQSVQTQKRFIADAAHQMKTPLAGLRMQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AELAQREQSPDELRRTLAHIADSSERTAHLVKQLLSLARMENMGAADGMVPLDLCALSRQ
HHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VVAEWLPKAWAKQIDLGFEEPGAPVTTSGNATMLAEMLNNLLDNAIRYTPDGGHVTVRVT
HHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEE
TAPFEPFVFLDVEDTGPGIPAGERERVMQRFYRILGTQAEGSGLGLAIVREIVQQHGGDI
ECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
AVLDYVYQSSPRLAGARFRITLPHGTPGEGASA
EEEHHHHHCCCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
GDRLAWPWRRPRAAPDRTAPGADDHDLADTLPHLENDATRPIARSLFGEILDWMLAPLL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LLWPMSIAVTYLVAKSIANAPYDRALESSAIVLSQQLHEVNGRVTLQLPISAREILRADE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCC
TDNIYYQVLGSSGEFVSGDRDLPLPPEEDAGAGSLVQLRDDRIHGAEIRVAYTYVQQPGA
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEEECCCCC
RPALVQVAETLDKRAQLANEIIKGVILPQFVILPLAVILVWFGLTRGLAPLNAIQERIRA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
RSPGDTSPIDEGAAPQELTPLVASFNELLGRLEQSVQTQKRFIADAAHQMKTPLAGLRMQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AELAQREQSPDELRRTLAHIADSSERTAHLVKQLLSLARMENMGAADGMVPLDLCALSRQ
HHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VVAEWLPKAWAKQIDLGFEEPGAPVTTSGNATMLAEMLNNLLDNAIRYTPDGGHVTVRVT
HHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEE
TAPFEPFVFLDVEDTGPGIPAGERERVMQRFYRILGTQAEGSGLGLAIVREIVQQHGGDI
ECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
AVLDYVYQSSPRLAGARFRITLPHGTPGEGASA
EEEHHHHHCCCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]