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The map label for this gene is ltrA [H]

Identifier: 17545261

GI number: 17545261

Start: 586608

End: 587525

Strand: Direct

Name: ltrA [H]

Synonym: RSc0542

Alternate gene names: 17545261

Gene position: 586608-587525 (Clockwise)

Preceding gene: 17545259

Following gene: 17545262

Centisome position: 15.78

GC content: 69.93

Gene sequence:

>918_bases
ATGGATCTCAACCAACTGGCGCTGTTCGTGCGCGTCGTCGAAGCGGGGAGCTTCACGGCGGCGGCGGTGCGGCTGGACTT
GCCCAAGTCGTCGGTCAGCCGGGGCATCGCCGCGCTCGAACAGGATTTGAACGTCCGGCTGCTACAGCGCACCACGCGCA
CGCTGCACCTGACCGATGCCGGCCAGAGCCTGTACCAGGTGGCGTCGCATGCACTGGAAGAGATCGAGCGCGCCACCACC
TGCGCCGGTGAACTGCAGGACCTGCCGCGCGGCAAGGTGCGCATGACGGCCCCCGAAGACGTCGGCCGGCTGCTGATCGC
GCCGATCGTGGCGCGCTTCATGCAGCAGTACCCCGACATCGACCTCGACGTGGTGCTGACGCCGCGCAACGTCGATCTCG
TGCAGGAGGGCTTCGATCTGGCGGTCCGCGTCGGGCGCCTGGCCGACAGTTCGCTGGTGGCCCGGCCGTTGGGCGTGCTG
CGCATCGGCCTGTTCGCCTCGCCGGACTACCTGCAGAAGCAGGGCGTGCCGCAGGCGGTGCGCGACCTGAGTCATCACAA
CTGCCTCGATTTCCGCGGCACCGGCCGCGGCGAGACGCAATGGCGCCTGGTCGGCCCCGACGGCCTGAAGACCGTGGCCG
TGCGCGCGCGCCTGAATGCCGACAGCCTGTCCTATCTCGAAACGCTGATCGCGAGCGGCGCCGGCATCGGCCCGCTGCCG
CTCTATGCCGGCGGCGTCGCCCGCGCCAACGCCCCGCTGCCGCGCCTGGTGCGGGTGCTGCCCGAATACGCCACCAGCGG
CGAGCCCCTGCATCTGGTCACGCCCACCGCCCGCTTCATTCCCAAGCGGGTCCGCCTGCTGATCGACATGCTGACGGAAG
CGATCCGCCACGAGCTGGACAGCAGCGATCCGGCATGA

Upstream 100 bases:

>100_bases
CCCCTTTTGCACTAGATGGGTATCGTGGGAAAAAATGTTGCCTGCAGCGGGACAATTAAACAAGGCAGGCCAGCCGGTCC
CACGATACGAGGAAGACACC

Downstream 100 bases:

>100_bases
GCCCGGCCTGGGGGCACTGACGCCGCCATCGTCAAATGTTGTGGCGCGTACGCTGTCGCGGGGCGCAGCGCGGCATGATT
CACCCCGCGCATGTCGGGCG

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDLNQLALFVRVVEAGSFTAAAVRLDLPKSSVSRGIAALEQDLNVRLLQRTTRTLHLTDAGQSLYQVASHALEEIERATT
CAGELQDLPRGKVRMTAPEDVGRLLIAPIVARFMQQYPDIDLDVVLTPRNVDLVQEGFDLAVRVGRLADSSLVARPLGVL
RIGLFASPDYLQKQGVPQAVRDLSHHNCLDFRGTGRGETQWRLVGPDGLKTVAVRARLNADSLSYLETLIASGAGIGPLP
LYAGGVARANAPLPRLVRVLPEYATSGEPLHLVTPTARFIPKRVRLLIDMLTEAIRHELDSSDPA

Sequences:

>Translated_305_residues
MDLNQLALFVRVVEAGSFTAAAVRLDLPKSSVSRGIAALEQDLNVRLLQRTTRTLHLTDAGQSLYQVASHALEEIERATT
CAGELQDLPRGKVRMTAPEDVGRLLIAPIVARFMQQYPDIDLDVVLTPRNVDLVQEGFDLAVRVGRLADSSLVARPLGVL
RIGLFASPDYLQKQGVPQAVRDLSHHNCLDFRGTGRGETQWRLVGPDGLKTVAVRARLNADSLSYLETLIASGAGIGPLP
LYAGGVARANAPLPRLVRVLPEYATSGEPLHLVTPTARFIPKRVRLLIDMLTEAIRHELDSSDPA
>Mature_305_residues
MDLNQLALFVRVVEAGSFTAAAVRLDLPKSSVSRGIAALEQDLNVRLLQRTTRTLHLTDAGQSLYQVASHALEEIERATT
CAGELQDLPRGKVRMTAPEDVGRLLIAPIVARFMQQYPDIDLDVVLTPRNVDLVQEGFDLAVRVGRLADSSLVARPLGVL
RIGLFASPDYLQKQGVPQAVRDLSHHNCLDFRGTGRGETQWRLVGPDGLKTVAVRARLNADSLSYLETLIASGAGIGPLP
LYAGGVARANAPLPRLVRVLPEYATSGEPLHLVTPTARFIPKRVRLLIDMLTEAIRHELDSSDPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=35.2542372881356, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=30.2721088435374, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=33.112582781457, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789440, Length=304, Percent_Identity=29.6052631578947, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=28.0821917808219, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=30.1369863013699, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87081978, Length=261, Percent_Identity=31.8007662835249, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=37.9310344827586, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788748, Length=186, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788706, Length=209, Percent_Identity=25.8373205741627, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788481, Length=320, Percent_Identity=25.9375, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787601, Length=125, Percent_Identity=30.4, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786448, Length=187, Percent_Identity=28.8770053475936, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI145693105, Length=159, Percent_Identity=24.5283018867925, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788297, Length=249, Percent_Identity=27.3092369477912, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33182; Mature: 33182

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNQLALFVRVVEAGSFTAAAVRLDLPKSSVSRGIAALEQDLNVRLLQRTTRTLHLTDA
CCHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEHH
GQSLYQVASHALEEIERATTCAGELQDLPRGKVRMTAPEDVGRLLIAPIVARFMQQYPDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCC
DLDVVLTPRNVDLVQEGFDLAVRVGRLADSSLVARPLGVLRIGLFASPDYLQKQGVPQAV
CEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHH
RDLSHHNCLDFRGTGRGETQWRLVGPDGLKTVAVRARLNADSLSYLETLIASGAGIGPLP
HHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEHEEEECCCHHHHHHHHHHHCCCCCCCCH
LYAGGVARANAPLPRLVRVLPEYATSGEPLHLVTPTARFIPKRVRLLIDMLTEAIRHELD
HHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
SSDPA
CCCCC
>Mature Secondary Structure
MDLNQLALFVRVVEAGSFTAAAVRLDLPKSSVSRGIAALEQDLNVRLLQRTTRTLHLTDA
CCHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEHH
GQSLYQVASHALEEIERATTCAGELQDLPRGKVRMTAPEDVGRLLIAPIVARFMQQYPDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCC
DLDVVLTPRNVDLVQEGFDLAVRVGRLADSSLVARPLGVLRIGLFASPDYLQKQGVPQAV
CEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHH
RDLSHHNCLDFRGTGRGETQWRLVGPDGLKTVAVRARLNADSLSYLETLIASGAGIGPLP
HHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEHEEEECCCHHHHHHHHHHHCCCCCCCCH
LYAGGVARANAPLPRLVRVLPEYATSGEPLHLVTPTARFIPKRVRLLIDMLTEAIRHELD
HHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
SSDPA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]