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The map label for this gene is regX3 [H]

Identifier: 17545262

GI number: 17545262

Start: 587961

End: 588701

Strand: Direct

Name: regX3 [H]

Synonym: RSc0543

Alternate gene names: 17545262

Gene position: 587961-588701 (Clockwise)

Preceding gene: 17545261

Following gene: 17545265

Centisome position: 15.82

GC content: 68.15

Gene sequence:

>741_bases
ATGCGCATCGCCTTGCTTGAGGACGATCCCTTCCAGAGCGAAGTCATCGCCCAGATCCTGTCCCAGTCCGGCCACGACGT
GGTGACGTTCACCAATGGCGCCACGCTGCTGCGCATGCTGGGCCGCTCGTCGTACGACATGCTCGTGCTCGACTGGCACA
CGCCCGGCATGCTGGGCATCGATCTGCTGAGTGTCGTGCGCAGCCGGCACCAGGAAGTCCTGCCGATCCTCTTCGTCACG
GCCGAGGCCCGCGAGCGGGGCCTGGTGCGGGCGCTGGGCCAGGGCGCGGACGACTACATCACCAAGCCGTTCCACATCCC
CGAGTTGCGCGCCCGTGTCGAAGCCCTGCTGCGCCGGGCCCACCCGGTACCGTACGCCGGCATGCCGTTCGCGGTCGGCC
CGTATTACTTCCATCCGCAGCGCCGGCTGGTCACGCTGCACGGCGCGCCGCTCGCGCTCACCGGCATCGAGTTCCAGCTG
GCCATGCTGCTGTTCGCCAACGCGGGCCGCACGCTGTCGCGCGACCACATCTTCGGGCAGGTCTGGGGCCGCAATTCGGC
GGAGTACACGCGCACGATCGACAGCCATGTGTCGCGCATCCGCCTGAAGCTGCGCCTCGAGCCGGTGAACGAGGTCCGGC
TGGTGGCGGTGTACAAGCACGGCTACCGCCTGGATCACCTGAGCGTCGCAGACAAGACCGGCACCCTGGCAGTATCCGTC
GCGGAACCCGCGGTGATCTAG

Upstream 100 bases:

>100_bases
GAAAATGCGGGCAGTGCAATCCATGCCACGGAGCGCATCCCGTCATGCCGGCCCGTCGTGACGCGCATGTGGCGCCTGCC
GCTTTTCATGGAGCCCGATC

Downstream 100 bases:

>100_bases
CGCCGCGGGTTGGAGGTCCGGCGACAAGCCAAGCACTAAGCGTGCGCTTCGGCCAGTTGCCGGATCCGCTGCAGCAGCAT
CCGGCGGATCAAGCCGCTGG

Product: response regulator transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRIALLEDDPFQSEVIAQILSQSGHDVVTFTNGATLLRMLGRSSYDMLVLDWHTPGMLGIDLLSVVRSRHQEVLPILFVT
AEARERGLVRALGQGADDYITKPFHIPELRARVEALLRRAHPVPYAGMPFAVGPYYFHPQRRLVTLHGAPLALTGIEFQL
AMLLFANAGRTLSRDHIFGQVWGRNSAEYTRTIDSHVSRIRLKLRLEPVNEVRLVAVYKHGYRLDHLSVADKTGTLAVSV
AEPAVI

Sequences:

>Translated_246_residues
MRIALLEDDPFQSEVIAQILSQSGHDVVTFTNGATLLRMLGRSSYDMLVLDWHTPGMLGIDLLSVVRSRHQEVLPILFVT
AEARERGLVRALGQGADDYITKPFHIPELRARVEALLRRAHPVPYAGMPFAVGPYYFHPQRRLVTLHGAPLALTGIEFQL
AMLLFANAGRTLSRDHIFGQVWGRNSAEYTRTIDSHVSRIRLKLRLEPVNEVRLVAVYKHGYRLDHLSVADKTGTLAVSV
AEPAVI
>Mature_246_residues
MRIALLEDDPFQSEVIAQILSQSGHDVVTFTNGATLLRMLGRSSYDMLVLDWHTPGMLGIDLLSVVRSRHQEVLPILFVT
AEARERGLVRALGQGADDYITKPFHIPELRARVEALLRRAHPVPYAGMPFAVGPYYFHPQRRLVTLHGAPLALTGIEFQL
AMLLFANAGRTLSRDHIFGQVWGRNSAEYTRTIDSHVSRIRLKLRLEPVNEVRLVAVYKHGYRLDHLSVADKTGTLAVSV
AEPAVI

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=204, Percent_Identity=38.2352941176471, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=32.8888888888889, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790860, Length=213, Percent_Identity=32.3943661971831, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=31.5315315315315, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=31.5789473684211, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1786784, Length=204, Percent_Identity=33.8235294117647, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=31.0810810810811, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367329, Length=211, Percent_Identity=33.6492890995261, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=29.5964125560538, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=27.9475982532751, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786911, Length=180, Percent_Identity=31.1111111111111, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787229, Length=209, Percent_Identity=28.7081339712919, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790299, Length=153, Percent_Identity=32.6797385620915, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=25.4310344827586, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=26.4462809917355, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27519; Mature: 27519

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIALLEDDPFQSEVIAQILSQSGHDVVTFTNGATLLRMLGRSSYDMLVLDWHTPGMLGI
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCEEEEEECCCCHHHH
DLLSVVRSRHQEVLPILFVTAEARERGLVRALGQGADDYITKPFHIPELRARVEALLRRA
HHHHHHHHHHHHEEEEEEEEECHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHC
HPVPYAGMPFAVGPYYFHPQRRLVTLHGAPLALTGIEFQLAMLLFANAGRTLSRDHIFGQ
CCCCCCCCCCCCCCEEECCCCEEEEEECCCEEEECHHHHHHHHHHHCCCCCCCCCCEEEE
VWGRNSAEYTRTIDSHVSRIRLKLRLEPVNEVRLVAVYKHGYRLDHLSVADKTGTLAVSV
ECCCCCCHHHHHHHHHHHEEEEEEEECCCCCEEEEEEEECCEEECEEEECCCCCEEEEEE
AEPAVI
CCCCCC
>Mature Secondary Structure
MRIALLEDDPFQSEVIAQILSQSGHDVVTFTNGATLLRMLGRSSYDMLVLDWHTPGMLGI
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCEEEEEECCCCHHHH
DLLSVVRSRHQEVLPILFVTAEARERGLVRALGQGADDYITKPFHIPELRARVEALLRRA
HHHHHHHHHHHHEEEEEEEEECHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHC
HPVPYAGMPFAVGPYYFHPQRRLVTLHGAPLALTGIEFQLAMLLFANAGRTLSRDHIFGQ
CCCCCCCCCCCCCCEEECCCCEEEEEECCCEEEECHHHHHHHHHHHCCCCCCCCCCEEEE
VWGRNSAEYTRTIDSHVSRIRLKLRLEPVNEVRLVAVYKHGYRLDHLSVADKTGTLAVSV
ECCCCCCHHHHHHHHHHHEEEEEEEECCCCCEEEEEEEECCEEECEEEECCCCCEEEEEE
AEPAVI
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA