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The map label for this gene is ubiH [H]

Identifier: 17545227

GI number: 17545227

Start: 543199

End: 544434

Strand: Reverse

Name: ubiH [H]

Synonym: RSc0508

Alternate gene names: 17545227

Gene position: 544434-543199 (Counterclockwise)

Preceding gene: 17545228

Following gene: 17545226

Centisome position: 14.65

GC content: 75.08

Gene sequence:

>1236_bases
ATGACCGATACCGCGGCGGCCACGCCGGACTTCGACATCGCCATCGTCGGCGCCGGGCCGGTCGGTCTGGCGCTGGCCAA
CTGGCTGCTGCGCGACACCGACTGGCGCATCGCCCTGTTCGATGCCCGCGACGCCGAGGCCGCCGCCCGCGACCCGCGCG
CGCTGGCGCTGTCGCACGGCTCGCGCGTGCTGCTCGAAGCGATCGGCAGCTGGCCGGCGCGCGCCACGCCGATCACGCAT
ATCCACGTCTCGCAGCGCGGCCACTTCGGCCAGACCCACATCCGCCGCGAGGACTACGACATCCCCGCGCTCGGCCACGT
CGTCCAGTACGGCGACCTGAGCGCCGCGCTCAACGCGGCGCTGGCCACGCAGGTGCAGCGCTACCCGGACCGGCTCGCAC
GCTACGACCACACGCCGGTCGAGCGCGTCGAGCAGCTGCCGCGCGCCGACGGCTCCGTGGCGCCGGCGCGCGTGCGGGCG
GCGCGCGAAGGGCGGCACCCGCTGGCCGTCGAAACCGCGGTCGTCATCCAGGCCGAAGGCGGCCTGTTCGACGATGCGCG
CCGGCAGGCCGCGAGGTCGTCGTACCTGCATCACACGCGGCACCGCGACTACGGCCAGACCGCCATCGTCGCCCACGTGC
GCTGCGCCGCGCCGCTCGAAGGCTGGGCGTGGGAGCGCTTCACCACCGAAGGACCGCTCGCGCTGCTGCCGCAGCACGAC
GCGGACGGCCCCGGCTACGCGCTGGTCTGGTGCTGCGCGCCCGACCAGGCGCGCCGCCGTGCCGGCCTGCCCGATGCGGC
CTTCCTGGCGGAGCTGGGTGCGGCCTTCGGCGAGCGCATGGGACGCTTCACGCAGGTCGGCCCGCGCCACACCTTCGCGC
TCGGGCTGCACGCCCGGCGTACGCCGGTCGACCGCCGCGTGGTCGCCATCGGCAATGCCGCGCAGACCATCCACCCGGTC
GCCGGCCAGGGCTTCAACCTGGGCCTGCGCGACGCCTTCGAACTGGCGCGTGCGCTGCGCGACGCCGTCACGCCGGCCGC
GCTCGCGCGCTTTGCCCGCGAACGCGCGTTCGACCGCGCCGTCACCATCGGCCTGACCGACCTGCTGCCGCGCGCCTTTG
CCGTGCCGGGCCGGCCGGTCGGGCACCTGCGCGGCATCGCGCTGACACTGCTCGAATGCGTGCCGCCGCTCAAGCACGAA
CTGGCGCGGCAGATGATGTTCGGGCAACGGGGCTAG

Upstream 100 bases:

>100_bases
TCGAGGACGATGCCATCGTCACGCCGCAGGGCTGCGAGCTGATCACGCGCGATGTGCCGGTGGCCGCGGACGACATCGAA
GCGCTGATGCGCAGCCAGGC

Downstream 100 bases:

>100_bases
CGCCGCCATCCAGCTTATGCACAGCGACACAGCGGCCCCGGCCGGGCGACGGGCCATCACGGTGGTGGGCGCCGGCATCG
TCGGCGTGTCATGCGCCTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTDTAAATPDFDIAIVGAGPVGLALANWLLRDTDWRIALFDARDAEAAARDPRALALSHGSRVLLEAIGSWPARATPITH
IHVSQRGHFGQTHIRREDYDIPALGHVVQYGDLSAALNAALATQVQRYPDRLARYDHTPVERVEQLPRADGSVAPARVRA
AREGRHPLAVETAVVIQAEGGLFDDARRQAARSSYLHHTRHRDYGQTAIVAHVRCAAPLEGWAWERFTTEGPLALLPQHD
ADGPGYALVWCCAPDQARRRAGLPDAAFLAELGAAFGERMGRFTQVGPRHTFALGLHARRTPVDRRVVAIGNAAQTIHPV
AGQGFNLGLRDAFELARALRDAVTPAALARFARERAFDRAVTIGLTDLLPRAFAVPGRPVGHLRGIALTLLECVPPLKHE
LARQMMFGQRG

Sequences:

>Translated_411_residues
MTDTAAATPDFDIAIVGAGPVGLALANWLLRDTDWRIALFDARDAEAAARDPRALALSHGSRVLLEAIGSWPARATPITH
IHVSQRGHFGQTHIRREDYDIPALGHVVQYGDLSAALNAALATQVQRYPDRLARYDHTPVERVEQLPRADGSVAPARVRA
AREGRHPLAVETAVVIQAEGGLFDDARRQAARSSYLHHTRHRDYGQTAIVAHVRCAAPLEGWAWERFTTEGPLALLPQHD
ADGPGYALVWCCAPDQARRRAGLPDAAFLAELGAAFGERMGRFTQVGPRHTFALGLHARRTPVDRRVVAIGNAAQTIHPV
AGQGFNLGLRDAFELARALRDAVTPAALARFARERAFDRAVTIGLTDLLPRAFAVPGRPVGHLRGIALTLLECVPPLKHE
LARQMMFGQRG
>Mature_410_residues
TDTAAATPDFDIAIVGAGPVGLALANWLLRDTDWRIALFDARDAEAAARDPRALALSHGSRVLLEAIGSWPARATPITHI
HVSQRGHFGQTHIRREDYDIPALGHVVQYGDLSAALNAALATQVQRYPDRLARYDHTPVERVEQLPRADGSVAPARVRAA
REGRHPLAVETAVVIQAEGGLFDDARRQAARSSYLHHTRHRDYGQTAIVAHVRCAAPLEGWAWERFTTEGPLALLPQHDA
DGPGYALVWCCAPDQARRRAGLPDAAFLAELGAAFGERMGRFTQVGPRHTFALGLHARRTPVDRRVVAIGNAAQTIHPVA
GQGFNLGLRDAFELARALRDAVTPAALARFARERAFDRAVTIGLTDLLPRAFAVPGRPVGHLRGIALTLLECVPPLKHEL
ARQMMFGQRG

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967307, Length=249, Percent_Identity=27.710843373494, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI32967305, Length=405, Percent_Identity=24.1975308641975, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789274, Length=416, Percent_Identity=35.3365384615385, Blast_Score=178, Evalue=7e-46,
Organism=Escherichia coli, GI1789273, Length=419, Percent_Identity=29.8329355608592, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1786883, Length=409, Percent_Identity=27.6283618581907, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920760, Length=226, Percent_Identity=28.7610619469027, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 44727; Mature: 44596

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTAAATPDFDIAIVGAGPVGLALANWLLRDTDWRIALFDARDAEAAARDPRALALSHG
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCEEEECCC
SRVLLEAIGSWPARATPITHIHVSQRGHFGQTHIRREDYDIPALGHVVQYGDLSAALNAA
CHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHCCHHHHHHHH
LATQVQRYPDRLARYDHTPVERVEQLPRADGSVAPARVRAAREGRHPLAVETAVVIQAEG
HHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEECC
GLFDDARRQAARSSYLHHTRHRDYGQTAIVAHVRCAAPLEGWAWERFTTEGPLALLPQHD
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCC
ADGPGYALVWCCAPDQARRRAGLPDAAFLAELGAAFGERMGRFTQVGPRHTFALGLHARR
CCCCCEEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
TPVDRRVVAIGNAAQTIHPVAGQGFNLGLRDAFELARALRDAVTPAALARFARERAFDRA
CCCCCEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VTIGLTDLLPRAFAVPGRPVGHLRGIALTLLECVPPLKHELARQMMFGQRG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDTAAATPDFDIAIVGAGPVGLALANWLLRDTDWRIALFDARDAEAAARDPRALALSHG
CCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCEEEECCC
SRVLLEAIGSWPARATPITHIHVSQRGHFGQTHIRREDYDIPALGHVVQYGDLSAALNAA
CHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHCCHHHHHHHH
LATQVQRYPDRLARYDHTPVERVEQLPRADGSVAPARVRAAREGRHPLAVETAVVIQAEG
HHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEECC
GLFDDARRQAARSSYLHHTRHRDYGQTAIVAHVRCAAPLEGWAWERFTTEGPLALLPQHD
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCC
ADGPGYALVWCCAPDQARRRAGLPDAAFLAELGAAFGERMGRFTQVGPRHTFALGLHARR
CCCCCEEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
TPVDRRVVAIGNAAQTIHPVAGQGFNLGLRDAFELARALRDAVTPAALARFARERAFDRA
CCCCCEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VTIGLTDLLPRAFAVPGRPVGHLRGIALTLLECVPPLKHELARQMMFGQRG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]