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The map label for this gene is yajR [H]

Identifier: 17545140

GI number: 17545140

Start: 449389

End: 450552

Strand: Direct

Name: yajR [H]

Synonym: RSc0421

Alternate gene names: 17545140

Gene position: 449389-450552 (Clockwise)

Preceding gene: 17545137

Following gene: 17545141

Centisome position: 12.09

GC content: 68.99

Gene sequence:

>1164_bases
ATGACCGGTTTCGAGTTGCGCGCCGCCACTTCGCTGGCCGGCATCTTCGCGCTGCGCATGCTGGGCCTGTTCATGATCAT
GCCGGTGTTCGCCGTGTTCGCGAAGTCGCTGCCGGACGGCGGCAACACCCAGCTGGTCGCTTTCGCCATCGGCGTGTACG
GCCTCACGCAAGCCGTGCTCTACATCCCCTACGGCTGGCTGTCGGACCGCTTCGGGCGCAAGCCGGTCATCGTGGCGGGG
CTGCTGATCTTTGCCGCGGGCAGCTTGGTGGCGGCGTTCTCGCACAGCGTGGCGGGCATCGCGGTGGGCCGGGCCATCCA
GGGCGCCGGCGCGATCTCGTCCGCGGTGATCGCCTTCGTGGCCGACCTGACGCGCGAGGAGCACCGCACCAAGGCGATGG
CGATGATCGGCGGCAGCATCGGCGTGTCGTTCGCCGTGGCCATTGTCAGCGCGCCGGTCATCTTCCGCTGGATCGGCATG
CCGGGCATGTTCCTGGCCATCGGCATCCTGGCGCTGATCGCCATCGGCGTGGTGCTGTGGGTCGTGCCGGATGCGCCGCG
CCCGGCGGCGCACGTGAGCGCGCCGTTCCGCGAGGTGCTGCACAACCGCGAGCTGCTGCGCCTGAACTTCGGCGTGTTCG
CGCTGCATGCCACGCAGACGGCGCTGTTCGTCGTGCTGCCGCACATGCTGGAGACCGCCGGCCTGCCGGTCGATTCGCAC
TGGAAGATCTACCTGCCGGTGATGGGCGTGTCGTTCGTGCTGATGGTGCCGGCCATCATCGCCGCGGAGAAGCGCGGCAA
GATGAAGGCGGTGCTGCTGTCGGCCGTCGCGCTGGTGATGGTGGCGCAGCTGGCGCTGGGCGAGGCGCAGCCGACGTTGG
CCTCGCTGACGGTCGCGCTGCTGGTGTACTTCCTCGGCTTCAACGTGCTGGAGGCCTCGCAGCCGTCGCTGGTCTCGAAA
TATGCGCCGGGCGTGCGCAAGGGCGCCGCGATGGGCGTCTACAACACGACGCAGGCGCTCGGGCTGTTCACGGGCGGGGC
CGGCGGCGGCTGGATTCTGCTGCATGCCGGGCAGCATGCGGTGTTCTTCACCTGCGCTGGCCTGGCGGCAGCCTGGCTTA
TAATCGCCAGTCCCATGCGGATGCCGGCGCTGCGTCGTCACTAA

Upstream 100 bases:

>100_bases
CGATTCGCGGGGCCGTTCAAGTGTCCTTGCCGTCGCTCGATGGCGGCGGTCCCCGCACATGTCTTCCGCTTCCCCACTCA
TGACTTCCGCCTCCGGCCGC

Downstream 100 bases:

>100_bases
AGCCGGCCGATACGGCGGCATCACTTACTTATCTTCGGAAACTCATCATGGCGTCCGTCAACAAAGTCATCATCGTCGGC
AATCTCGGCGCCGATCCCGA

Product: multidrug-efflux transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTGFELRAATSLAGIFALRMLGLFMIMPVFAVFAKSLPDGGNTQLVAFAIGVYGLTQAVLYIPYGWLSDRFGRKPVIVAG
LLIFAAGSLVAAFSHSVAGIAVGRAIQGAGAISSAVIAFVADLTREEHRTKAMAMIGGSIGVSFAVAIVSAPVIFRWIGM
PGMFLAIGILALIAIGVVLWVVPDAPRPAAHVSAPFREVLHNRELLRLNFGVFALHATQTALFVVLPHMLETAGLPVDSH
WKIYLPVMGVSFVLMVPAIIAAEKRGKMKAVLLSAVALVMVAQLALGEAQPTLASLTVALLVYFLGFNVLEASQPSLVSK
YAPGVRKGAAMGVYNTTQALGLFTGGAGGGWILLHAGQHAVFFTCAGLAAAWLIIASPMRMPALRRH

Sequences:

>Translated_387_residues
MTGFELRAATSLAGIFALRMLGLFMIMPVFAVFAKSLPDGGNTQLVAFAIGVYGLTQAVLYIPYGWLSDRFGRKPVIVAG
LLIFAAGSLVAAFSHSVAGIAVGRAIQGAGAISSAVIAFVADLTREEHRTKAMAMIGGSIGVSFAVAIVSAPVIFRWIGM
PGMFLAIGILALIAIGVVLWVVPDAPRPAAHVSAPFREVLHNRELLRLNFGVFALHATQTALFVVLPHMLETAGLPVDSH
WKIYLPVMGVSFVLMVPAIIAAEKRGKMKAVLLSAVALVMVAQLALGEAQPTLASLTVALLVYFLGFNVLEASQPSLVSK
YAPGVRKGAAMGVYNTTQALGLFTGGAGGGWILLHAGQHAVFFTCAGLAAAWLIIASPMRMPALRRH
>Mature_386_residues
TGFELRAATSLAGIFALRMLGLFMIMPVFAVFAKSLPDGGNTQLVAFAIGVYGLTQAVLYIPYGWLSDRFGRKPVIVAGL
LIFAAGSLVAAFSHSVAGIAVGRAIQGAGAISSAVIAFVADLTREEHRTKAMAMIGGSIGVSFAVAIVSAPVIFRWIGMP
GMFLAIGILALIAIGVVLWVVPDAPRPAAHVSAPFREVLHNRELLRLNFGVFALHATQTALFVVLPHMLETAGLPVDSHW
KIYLPVMGVSFVLMVPAIIAAEKRGKMKAVLLSAVALVMVAQLALGEAQPTLASLTVALLVYFLGFNVLEASQPSLVSKY
APGVRKGAAMGVYNTTQALGLFTGGAGGGWILLHAGQHAVFFTCAGLAAAWLIIASPMRMPALRRH

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081738, Length=387, Percent_Identity=47.8036175710594, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI48994889, Length=254, Percent_Identity=30.7086614173228, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40638; Mature: 40507

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGFELRAATSLAGIFALRMLGLFMIMPVFAVFAKSLPDGGNTQLVAFAIGVYGLTQAVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHH
YIPYGWLSDRFGRKPVIVAGLLIFAAGSLVAAFSHSVAGIAVGRAIQGAGAISSAVIAFV
HCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ADLTREEHRTKAMAMIGGSIGVSFAVAIVSAPVIFRWIGMPGMFLAIGILALIAIGVVLW
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VVPDAPRPAAHVSAPFREVLHNRELLRLNFGVFALHATQTALFVVLPHMLETAGLPVDSH
HCCCCCCCCHHCCHHHHHHHCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHCCCCCCCC
WKIYLPVMGVSFVLMVPAIIAAEKRGKMKAVLLSAVALVMVAQLALGEAQPTLASLTVAL
CEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LVYFLGFNVLEASQPSLVSKYAPGVRKGAAMGVYNTTQALGLFTGGAGGGWILLHAGQHA
HHHHHCCHHHCCCCCHHHHHHCCCHHCCCCCCCCCHHHHHHEEECCCCCCEEEEECCCCE
VFFTCAGLAAAWLIIASPMRMPALRRH
EEHHHHHHHHHHHHHHCCCCCCHHCCC
>Mature Secondary Structure 
TGFELRAATSLAGIFALRMLGLFMIMPVFAVFAKSLPDGGNTQLVAFAIGVYGLTQAVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHH
YIPYGWLSDRFGRKPVIVAGLLIFAAGSLVAAFSHSVAGIAVGRAIQGAGAISSAVIAFV
HCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ADLTREEHRTKAMAMIGGSIGVSFAVAIVSAPVIFRWIGMPGMFLAIGILALIAIGVVLW
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VVPDAPRPAAHVSAPFREVLHNRELLRLNFGVFALHATQTALFVVLPHMLETAGLPVDSH
HCCCCCCCCHHCCHHHHHHHCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHCCCCCCCC
WKIYLPVMGVSFVLMVPAIIAAEKRGKMKAVLLSAVALVMVAQLALGEAQPTLASLTVAL
CEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LVYFLGFNVLEASQPSLVSKYAPGVRKGAAMGVYNTTQALGLFTGGAGGGWILLHAGQHA
HHHHHCCHHHCCCCCHHHHHHCCCHHCCCCCCCCCHHHHHHEEECCCCCCEEEEECCCCE
VFFTCAGLAAAWLIIASPMRMPALRRH
EEHHHHHHHHHHHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]