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The map label for this gene is ipk [H]

Identifier: 17545115

GI number: 17545115

Start: 423179

End: 424048

Strand: Reverse

Name: ipk [H]

Synonym: RSc0396

Alternate gene names: 17545115

Gene position: 424048-423179 (Counterclockwise)

Preceding gene: 17545116

Following gene: 17545114

Centisome position: 11.41

GC content: 65.75

Gene sequence:

>870_bases
ATGCCCTCCGCGCCCACCGAACTGCGCGACTGTCCCGCGCCCGCCAAGCTCAACCTGTTCCTGCACGTGGTCGGCCGCCG
GCCGGACGGCTATCACCTGCTGCAGACCGTGTTCCAGCTGATCGACTGGTGCGACACCCTGCACTTCGGCCGCCGCGCCG
ACGGCCGCTTGGTGCGCACCACCGACATCCCCGGCGTTCCGGCGGACGAAGACCTGGTCATCCGCGCCGCCCGCCTGCTG
CAGGCGGAGACCGGCTGCGCCTACGGCGCCGACATCGCGCTGGAAAAGCGCCTGCCGATGGGCGGCGGCATCGGCGGCGG
CTCGTCCGATGCGGCGACGGCGCTGCTGGCGCTCAACCGCCTGTGGGGGCTCGACCTGCCGCGCGCGAAGCTGATGTCGC
TGGGCCTGCGCCTGGGCGCTGACGTGCCTTTCTTCCTGTTCGGCCAGAACGCATTTGCCGAGGGCATCGGTGAAGCGCTG
ACACCGATCGCGCTGCCGCCGGCGACCTTTGTGGTCATCCATCCGCGCGTCCATGTCCCCACCCCCGAAATTTTTTCCGA
TGAGGGGTTGACACGTAACACTCCCCTCACCATAATTACGGACTTTCCTGACCAACAAATTGTTTTCGCTTACGGTCGCA
ACGATCTGCAAGCGGTGGCGGAAAGGAAATACGGCGAAATCGCCCGAGCTCTTGCCTGGCTGCGTCAGTTCAGCCCACTG
GCAAGGATGACCGGATCCGGCGCCTGCGTGTTCGCACCGTTTGATCGTGCAGAACAGGCACAAGCGGTGGCGGATCAGGT
GCCTTCCGAATGGGAAGGTCGGTGTGCGGCAGGTCTGACGCATCACCCGCTCGCGATGTTCGCTGTATAA

Upstream 100 bases:

>100_bases
ACGCCGGCTGGATCTCGACCGGCCCCAGGGCGCGGGCGGCGCGCCGGGCCCGCTGTCCGTGCGCCTCGTGCTCGACCAGT
AAGACCGTCACCATCCCGCC

Downstream 100 bases:

>100_bases
GGTTTGCAGCTTTTGCTTCTGCAACGGAAGCAAGGGCCGATCGGTTGTGTAGGGGAGTCGCCAAGTTGGTTAAGGCACCG
GATTTTGATTCCGGCATGCG

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MPSAPTELRDCPAPAKLNLFLHVVGRRPDGYHLLQTVFQLIDWCDTLHFGRRADGRLVRTTDIPGVPADEDLVIRAARLL
QAETGCAYGADIALEKRLPMGGGIGGGSSDAATALLALNRLWGLDLPRAKLMSLGLRLGADVPFFLFGQNAFAEGIGEAL
TPIALPPATFVVIHPRVHVPTPEIFSDEGLTRNTPLTIITDFPDQQIVFAYGRNDLQAVAERKYGEIARALAWLRQFSPL
ARMTGSGACVFAPFDRAEQAQAVADQVPSEWEGRCAAGLTHHPLAMFAV

Sequences:

>Translated_289_residues
MPSAPTELRDCPAPAKLNLFLHVVGRRPDGYHLLQTVFQLIDWCDTLHFGRRADGRLVRTTDIPGVPADEDLVIRAARLL
QAETGCAYGADIALEKRLPMGGGIGGGSSDAATALLALNRLWGLDLPRAKLMSLGLRLGADVPFFLFGQNAFAEGIGEAL
TPIALPPATFVVIHPRVHVPTPEIFSDEGLTRNTPLTIITDFPDQQIVFAYGRNDLQAVAERKYGEIARALAWLRQFSPL
ARMTGSGACVFAPFDRAEQAQAVADQVPSEWEGRCAAGLTHHPLAMFAV
>Mature_288_residues
PSAPTELRDCPAPAKLNLFLHVVGRRPDGYHLLQTVFQLIDWCDTLHFGRRADGRLVRTTDIPGVPADEDLVIRAARLLQ
AETGCAYGADIALEKRLPMGGGIGGGSSDAATALLALNRLWGLDLPRAKLMSLGLRLGADVPFFLFGQNAFAEGIGEALT
PIALPPATFVVIHPRVHVPTPEIFSDEGLTRNTPLTIITDFPDQQIVFAYGRNDLQAVAERKYGEIARALAWLRQFSPLA
RMTGSGACVFAPFDRAEQAQAVADQVPSEWEGRCAAGLTHHPLAMFAV

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=279, Percent_Identity=46.5949820788531, Blast_Score=228, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 31257; Mature: 31126

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSAPTELRDCPAPAKLNLFLHVVGRRPDGYHLLQTVFQLIDWCDTLHFGRRADGRLVRT
CCCCCCCHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
TDIPGVPADEDLVIRAARLLQAETGCAYGADIALEKRLPMGGGIGGGSSDAATALLALNR
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
LWGLDLPRAKLMSLGLRLGADVPFFLFGQNAFAEGIGEALTPIALPPATFVVIHPRVHVP
HHCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCCCCCCEEEEECCEEECC
TPEIFSDEGLTRNTPLTIITDFPDQQIVFAYGRNDLQAVAERKYGEIARALAWLRQFSPL
CCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHH
ARMTGSGACVFAPFDRAEQAQAVADQVPSEWEGRCAAGLTHHPLAMFAV
HHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
PSAPTELRDCPAPAKLNLFLHVVGRRPDGYHLLQTVFQLIDWCDTLHFGRRADGRLVRT
CCCCCCHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
TDIPGVPADEDLVIRAARLLQAETGCAYGADIALEKRLPMGGGIGGGSSDAATALLALNR
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
LWGLDLPRAKLMSLGLRLGADVPFFLFGQNAFAEGIGEALTPIALPPATFVVIHPRVHVP
HHCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCCCCCCEEEEECCEEECC
TPEIFSDEGLTRNTPLTIITDFPDQQIVFAYGRNDLQAVAERKYGEIARALAWLRQFSPL
CCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHH
ARMTGSGACVFAPFDRAEQAQAVADQVPSEWEGRCAAGLTHHPLAMFAV
HHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA