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The map label for this gene is lolB

Identifier: 17545116

GI number: 17545116

Start: 424067

End: 424696

Strand: Reverse

Name: lolB

Synonym: RSc0397

Alternate gene names: 17545116

Gene position: 424696-424067 (Counterclockwise)

Preceding gene: 17545117

Following gene: 17545115

Centisome position: 11.43

GC content: 72.7

Gene sequence:

>630_bases
ATGGCGACCGTGTTTTCGCGAGCGCTCGGCGCGCTGGTGCTGGGTGTTGCGTGCGCGCTGCTTGCAGGCTGCGCCAGCGT
ACGGCCGGCCAACGACCTCTTCGCCGGCACGCAAGACGGCGACGCCACCATCACGCGCTACCAGGGCCGCTTTTCGGCGC
GCTACGTGCAGGACGACGCGCAGCAGAGCGCGGTTGGCAGCTTCCTGTGGCGCGAACGGGGGGCGGACGTGCAGCTGGAG
CTGATGTCGCCGCTGGGCCAGACGCTCGCCATCGTCAGCCAGAACCGGCAGGGCGCCACCCTGGAACTGCCTAACCAGCC
GCCGCGCCGCGCCGCCGAAGTGGATACGCTGATGCAGGACGCGCTCGGCTTCTCGCTGCCGGTCTCCGGCCTGCGCGACT
GGCTGCGCGCGCGCCCCACGCCCGGCACGCCGGCCCGCGTGGCGCGCGACGCGCAATCGCGCCCCGAGACCATTGAGCAG
AACGGGTGGACGGTGCACTACGTCGCCTGGAGCGACGATGGCGACAACAGCACCGCCAATGCCCGCGTACGCCGGCTGGA
TCTCGACCGGCCCCAGGGCGCGGGCGGCGCGCCGGGCCCGCTGTCCGTGCGCCTCGTGCTCGACCAGTAA

Upstream 100 bases:

>100_bases
GGACCGAAGCCGCCAAGCTCGATATCAACGACACGACCCTGCGCGAGACACTGCACCGCTTCAGCCAGCCGCTGCCGGAC
GCGCCCACGAGCGCGAACTG

Downstream 100 bases:

>100_bases
GACCGTCACCATCCCGCCATGCCCTCCGCGCCCACCGAACTGCGCGACTGTCCCGCGCCCGCCAAGCTCAACCTGTTCCT
GCACGTGGTCGGCCGCCGGC

Product: outer membrane lipoprotein LolB

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MATVFSRALGALVLGVACALLAGCASVRPANDLFAGTQDGDATITRYQGRFSARYVQDDAQQSAVGSFLWRERGADVQLE
LMSPLGQTLAIVSQNRQGATLELPNQPPRRAAEVDTLMQDALGFSLPVSGLRDWLRARPTPGTPARVARDAQSRPETIEQ
NGWTVHYVAWSDDGDNSTANARVRRLDLDRPQGAGGAPGPLSVRLVLDQ

Sequences:

>Translated_209_residues
MATVFSRALGALVLGVACALLAGCASVRPANDLFAGTQDGDATITRYQGRFSARYVQDDAQQSAVGSFLWRERGADVQLE
LMSPLGQTLAIVSQNRQGATLELPNQPPRRAAEVDTLMQDALGFSLPVSGLRDWLRARPTPGTPARVARDAQSRPETIEQ
NGWTVHYVAWSDDGDNSTANARVRRLDLDRPQGAGGAPGPLSVRLVLDQ
>Mature_208_residues
ATVFSRALGALVLGVACALLAGCASVRPANDLFAGTQDGDATITRYQGRFSARYVQDDAQQSAVGSFLWRERGADVQLEL
MSPLGQTLAIVSQNRQGATLELPNQPPRRAAEVDTLMQDALGFSLPVSGLRDWLRARPTPGTPARVARDAQSRPETIEQN
GWTVHYVAWSDDGDNSTANARVRRLDLDRPQGAGGAPGPLSVRLVLDQ

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LOLB_RALSO (Q8Y2D9)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_518518.1
- ProteinModelPortal:   Q8Y2D9
- SMR:   Q8Y2D9
- GeneID:   1219201
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0397
- NMPDR:   fig|267608.1.peg.397
- HOGENOM:   HBG451855
- OMA:   KPPLDIK
- ProtClustDB:   PRK00022
- BioCyc:   RSOL267608:RSC0397-MONOMER
- HAMAP:   MF_00233
- InterPro:   IPR004565
- TIGRFAMs:   TIGR00548

Pfam domain/function: PF03550 LolB

EC number: NA

Molecular weight: Translated: 22438; Mature: 22307

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVFSRALGALVLGVACALLAGCASVRPANDLFAGTQDGDATITRYQGRFSARYVQDDA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHH
QQSAVGSFLWRERGADVQLELMSPLGQTLAIVSQNRQGATLELPNQPPRRAAEVDTLMQD
HHHHHHHHHHHHCCCCEEEEEHHHCHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHH
ALGFSLPVSGLRDWLRARPTPGTPARVARDAQSRPETIEQNGWTVHYVAWSDDGDNSTAN
HHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHCCCCEEEEEEECCCCCCCCCC
ARVRRLDLDRPQGAGGAPGPLSVRLVLDQ
CEEEEEECCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
ATVFSRALGALVLGVACALLAGCASVRPANDLFAGTQDGDATITRYQGRFSARYVQDDA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHH
QQSAVGSFLWRERGADVQLELMSPLGQTLAIVSQNRQGATLELPNQPPRRAAEVDTLMQD
HHHHHHHHHHHHCCCCEEEEEHHHCHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHH
ALGFSLPVSGLRDWLRARPTPGTPARVARDAQSRPETIEQNGWTVHYVAWSDDGDNSTAN
HHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHCCCCEEEEEEECCCCCCCCCC
ARVRRLDLDRPQGAGGAPGPLSVRLVLDQ
CEEEEEECCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852