Click here to switch to the map view.

The map label for this gene is ygbM [C]

Identifier: 17544739

GI number: 17544739

Start: 23149

End: 23937

Strand: Reverse

Name: ygbM [C]

Synonym: RSc0020

Alternate gene names: 17544739

Gene position: 23937-23149 (Counterclockwise)

Preceding gene: 17544740

Following gene: 17544735

Centisome position: 0.64

GC content: 68.95

Gene sequence:

>789_bases
ATGCCACGCTTTGCCGCCAACCTGACGATGATGTACCCGGAACATGCGTTCCTCGACCGCTTCACCGCCGCCGCGCGCGA
TGGGTTCGAAGGCGTGGAATTCCTGTTCCCTTACGACTACGACAAGACCGAGCTGCGAACGCGGCTGGACGACAACGGCC
TCGCACAGGCGCTGTTCAACGCACCGCCGGGCGACTGGGCGGGCGGCGAGCGCGGCATCGCCTCGCTGCCCGGCCGCGAA
GACGAATTCAAGCGCGGCATCGCCACCGCGCTCGACTACGCACAGGCGCTCGGCAATACGCGCGTGCACGTCGTGGCCGG
CCTGATCGGCCCGCACGACGATCGTGCCCGCCACCACGCCACCTACGTGCAGAACCTCGCCCATGCGGCGCGCGAGGCGG
CCAGCGCCGGCATCACCATCGTGCTGGAGCCGATCAACACGCGCGACATGCCGGGCTTCTTCCTCACGCACCAGGCCCAG
GCGCACGCGGTCTGCCGGGAAGTCGGCGCGCCCAACCTGAAGGTGCAGTTCGACCTGTATCACGCGCAGATCATGGAGGG
CGACCTGTCGGTCAAGCTGCGCGAGTACCTCGACGGCATCGGCCACGTGCAGATCGCGGGCGTCCCCGATCGCCACGAGC
CGGACGAGGGCGAGCTGAACTATCCGCACCTCTTCGCGCTGATGGATGCGCTCGGCTACCGCGGCTGGGTCGGCTGCGAA
TACCGGCCGCGCGCCGGCACCAGCGAAGGGCTGGGATGGTTCAAGCGCTGGCGCGCGCACCAGCGCTGA

Upstream 100 bases:

>100_bases
CAGGCCGAGCTGGTGAAGTTCGCGGTGGAAGCGGGCAAGGAGCGCTGAGGCTCGCCGCTCATCAGCCCATCGCCGCCCCC
CGATCCGAGGAGCCCCTGTC

Downstream 100 bases:

>100_bases
CCGCGCCCGGCAAAAGCAGCGGCCGGCACTGTCTGCACAGGCCGGCCGCGCTGGTCTGGCACACCGTGCCGGGTTACGAC
TTGCAGGCGCCCAGGTAGCG

Product: hypothetical protein

Products: 2-hydroxy-3-oxopropanoate

Alternate protein names: ORF4 [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MPRFAANLTMMYPEHAFLDRFTAAARDGFEGVEFLFPYDYDKTELRTRLDDNGLAQALFNAPPGDWAGGERGIASLPGRE
DEFKRGIATALDYAQALGNTRVHVVAGLIGPHDDRARHHATYVQNLAHAAREAASAGITIVLEPINTRDMPGFFLTHQAQ
AHAVCREVGAPNLKVQFDLYHAQIMEGDLSVKLREYLDGIGHVQIAGVPDRHEPDEGELNYPHLFALMDALGYRGWVGCE
YRPRAGTSEGLGWFKRWRAHQR

Sequences:

>Translated_262_residues
MPRFAANLTMMYPEHAFLDRFTAAARDGFEGVEFLFPYDYDKTELRTRLDDNGLAQALFNAPPGDWAGGERGIASLPGRE
DEFKRGIATALDYAQALGNTRVHVVAGLIGPHDDRARHHATYVQNLAHAAREAASAGITIVLEPINTRDMPGFFLTHQAQ
AHAVCREVGAPNLKVQFDLYHAQIMEGDLSVKLREYLDGIGHVQIAGVPDRHEPDEGELNYPHLFALMDALGYRGWVGCE
YRPRAGTSEGLGWFKRWRAHQR
>Mature_261_residues
PRFAANLTMMYPEHAFLDRFTAAARDGFEGVEFLFPYDYDKTELRTRLDDNGLAQALFNAPPGDWAGGERGIASLPGRED
EFKRGIATALDYAQALGNTRVHVVAGLIGPHDDRARHHATYVQNLAHAAREAASAGITIVLEPINTRDMPGFFLTHQAQA
HAVCREVGAPNLKVQFDLYHAQIMEGDLSVKLREYLDGIGHVQIAGVPDRHEPDEGELNYPHLFALMDALGYRGWVGCEY
RPRAGTSEGLGWFKRWRAHQR

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=262, Percent_Identity=44.6564885496183, Blast_Score=218, Evalue=4e-57,
Organism=Homo sapiens, GI300068964, Length=243, Percent_Identity=44.0329218106996, Blast_Score=193, Evalue=1e-49,
Organism=Escherichia coli, GI1789095, Length=258, Percent_Identity=48.4496124031008, Blast_Score=261, Evalue=3e-71,
Organism=Escherichia coli, GI1786718, Length=258, Percent_Identity=48.8372093023256, Blast_Score=260, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI17552022, Length=240, Percent_Identity=38.3333333333333, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI17530883, Length=260, Percent_Identity=35.3846153846154, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: 5.3.1.22

Molecular weight: Translated: 29237; Mature: 29106

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFAANLTMMYPEHAFLDRFTAAARDGFEGVEFLFPYDYDKTELRTRLDDNGLAQALFN
CCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHC
APPGDWAGGERGIASLPGREDEFKRGIATALDYAQALGNTRVHVVAGLIGPHDDRARHHA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHH
TYVQNLAHAAREAASAGITIVLEPINTRDMPGFFLTHQAQAHAVCREVGAPNLKVQFDLY
HHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEEEE
HAQIMEGDLSVKLREYLDGIGHVQIAGVPDRHEPDEGELNYPHLFALMDALGYRGWVGCE
EHHHHCCCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
YRPRAGTSEGLGWFKRWRAHQR
CCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
PRFAANLTMMYPEHAFLDRFTAAARDGFEGVEFLFPYDYDKTELRTRLDDNGLAQALFN
CCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHC
APPGDWAGGERGIASLPGREDEFKRGIATALDYAQALGNTRVHVVAGLIGPHDDRARHHA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHH
TYVQNLAHAAREAASAGITIVLEPINTRDMPGFFLTHQAQAHAVCREVGAPNLKVQFDLY
HHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEEEE
HAQIMEGDLSVKLREYLDGIGHVQIAGVPDRHEPDEGELNYPHLFALMDALGYRGWVGCE
EHHHHCCCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
YRPRAGTSEGLGWFKRWRAHQR
CCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate

Specific reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate; Other Name(s): hydroxypyruvate ketol-isomerase

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7851418 [H]