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The map label for this gene is oxaA

Identifier: 17544723

GI number: 17544723

Start: 1431

End: 3092

Strand: Direct

Name: oxaA

Synonym: RSc0004

Alternate gene names: 17544723

Gene position: 1431-3092 (Clockwise)

Preceding gene: 17544722

Following gene: 17544724

Centisome position: 0.04

GC content: 65.76

Gene sequence:

>1662_bases
ATGGATATCAAACGCACCATTCTCTGGGTGATCTTCTCGCTGTCGGTTGTCCTGCTGTTCGACAACTGGCAACGCGCGAA
CGGCCACCAGTCGATGTTCTTCCCGACGCCGCAGACGGTCACCACGACCGCCGCCGCACCGGGCGGTACGCCCGCGGGCG
ATGTGCCCAAGGCCGCCGCGCCGGCCGCCGCCGGCAGCCAGGCGGCCCCGGCCACCGGTGCCGTCTCGCAGACGCCGGCT
TCGGAAAAGATCGTCGTCACGACGGACGTGATCCGCGCAACGGTGGATACGGCCGGTGCCATCGTCACCAAGCTTGAGCT
GCTGACGCAGAAGGACCACGACGGCAACCCGATGGTGCTGTTCGACCGCAGCCTGGAGCGTACCTATCTGGCGCGCTCGG
GCCTGATCGGCGGCGATTTCCCGAACCACACCACGGTGTTCACGGCGTCCGCCGGCCCGCGTGACCTGGGCACCGGCGGC
GAAGTCTCGCTCACGCTCACCGCCGACAAGGGCGGCGCCAAGCTGGCCAAGACCTACGTCTTCAAGCGCGGCAGCTATGT
GATCGACACGCGCTTCGACGTGACCAACGACGGTGCCGCGCCGATCAACCCGACGCTGTACATGGAACTGGCGCGCGACG
GCGGCGCGGTGGAGCAATCGCGCTTCTACAGCACGTTCACCGGTCCGGCCGTCTACACCGACACCGACCACTATCACAAG
ATCACCTTCGCCGACATCGACAAGAGCAAGGCTCACGTGCCGGCCCCGACCGACAGCGGCTGGGTGGCGATGGTGCAGCA
CTACTTTGCATCGGCATGGATTCCGGCGGCCAGCGCCAAGCGCGAGTTCTACGTCGACCGCATCGACACCAACTTCTACC
GCGTCGGCATGCAGCAGGCGCTGGGCACGGTGGCGCCGGGCGCGAGCGTGTCGGCCACGGCACGCCTGTTCGCCGGTCCG
CAGGAAGAGCGCATGCTCGAGGGCATCACCCCGGGCCTGGAACTGGTGAAGGACTACGGCTGGCTGACCATCATCGCCAA
GCCGCTGTTCTGGCTGCTCGAGAAGATCCACAAGCTGCTGGGCAACTGGGGCTGGTCGATCGTGGCGCTGACCGTGCTGG
TCAAGCTGGTGTTCTTCCCGCTGTCGGCCACCAGCTACCGCTCGATGGCCAAGATGAAGGACCTGCAGCCGCGCATGACG
GCCATCCGCGAGCGCCACAAGGGCGACCCGCAGAAGATGAACCAGGAGATGATGACGCTGTATCGCACCGAGAAGGTCAA
TCCGCTCGGCGGCTGCCTGCCGATCGTGATCCAGATCCCGGTGTTCATCGCGCTGTACTGGGTGCTGCTGTCGTCCGTGG
AAATGCGCGGCGCGCCGTGGCTGGGCTGGGTGCACGACCTGGCCTCGCCGGACCCGTTCTACATCCTGCCGATCCTGATG
GCCGTGTCGATGTTCGTGCAGACCCGCCTGAACCCGACCCCGCCGGACCCCGTGCAGGCCAAGATGATGATGTTCATGCC
GATCGCGTTCTCGGTGATGTTCTTCTTCTTCCCGGCCGGCCTGGTGCTGTACTGGGTGGTCAACAACTGCCTGTCGATCG
CGCAGCAGTGGTCGATCAACCGCATGCTGGGCACCAATAAGAAGGCCGCGGCCGCCAAGTAA

Upstream 100 bases:

>100_bases
CGCTGCGCTGCGCTCCACCGATTCCGCATCGACCGAGACGACCGCAGCCGACGCACCGGCCGCGCGGCCGTCGATTCACC
TTCCCAGACCGTAATCCGAC

Downstream 100 bases:

>100_bases
GGCAGATCGGCCGCAGCAGGAAGGGCACCCTCGGGTGCCCTTTTTTCATGCCGGTGCGCGGCGGGCTGTCGTGCATCGTA
TCGAATGGACGCTGACACTT

Product: inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MDIKRTILWVIFSLSVVLLFDNWQRANGHQSMFFPTPQTVTTTAAAPGGTPAGDVPKAAAPAAAGSQAAPATGAVSQTPA
SEKIVVTTDVIRATVDTAGAIVTKLELLTQKDHDGNPMVLFDRSLERTYLARSGLIGGDFPNHTTVFTASAGPRDLGTGG
EVSLTLTADKGGAKLAKTYVFKRGSYVIDTRFDVTNDGAAPINPTLYMELARDGGAVEQSRFYSTFTGPAVYTDTDHYHK
ITFADIDKSKAHVPAPTDSGWVAMVQHYFASAWIPAASAKREFYVDRIDTNFYRVGMQQALGTVAPGASVSATARLFAGP
QEERMLEGITPGLELVKDYGWLTIIAKPLFWLLEKIHKLLGNWGWSIVALTVLVKLVFFPLSATSYRSMAKMKDLQPRMT
AIRERHKGDPQKMNQEMMTLYRTEKVNPLGGCLPIVIQIPVFIALYWVLLSSVEMRGAPWLGWVHDLASPDPFYILPILM
AVSMFVQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYWVVNNCLSIAQQWSINRMLGTNKKAAAAK

Sequences:

>Translated_553_residues
MDIKRTILWVIFSLSVVLLFDNWQRANGHQSMFFPTPQTVTTTAAAPGGTPAGDVPKAAAPAAAGSQAAPATGAVSQTPA
SEKIVVTTDVIRATVDTAGAIVTKLELLTQKDHDGNPMVLFDRSLERTYLARSGLIGGDFPNHTTVFTASAGPRDLGTGG
EVSLTLTADKGGAKLAKTYVFKRGSYVIDTRFDVTNDGAAPINPTLYMELARDGGAVEQSRFYSTFTGPAVYTDTDHYHK
ITFADIDKSKAHVPAPTDSGWVAMVQHYFASAWIPAASAKREFYVDRIDTNFYRVGMQQALGTVAPGASVSATARLFAGP
QEERMLEGITPGLELVKDYGWLTIIAKPLFWLLEKIHKLLGNWGWSIVALTVLVKLVFFPLSATSYRSMAKMKDLQPRMT
AIRERHKGDPQKMNQEMMTLYRTEKVNPLGGCLPIVIQIPVFIALYWVLLSSVEMRGAPWLGWVHDLASPDPFYILPILM
AVSMFVQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYWVVNNCLSIAQQWSINRMLGTNKKAAAAK
>Mature_553_residues
MDIKRTILWVIFSLSVVLLFDNWQRANGHQSMFFPTPQTVTTTAAAPGGTPAGDVPKAAAPAAAGSQAAPATGAVSQTPA
SEKIVVTTDVIRATVDTAGAIVTKLELLTQKDHDGNPMVLFDRSLERTYLARSGLIGGDFPNHTTVFTASAGPRDLGTGG
EVSLTLTADKGGAKLAKTYVFKRGSYVIDTRFDVTNDGAAPINPTLYMELARDGGAVEQSRFYSTFTGPAVYTDTDHYHK
ITFADIDKSKAHVPAPTDSGWVAMVQHYFASAWIPAASAKREFYVDRIDTNFYRVGMQQALGTVAPGASVSATARLFAGP
QEERMLEGITPGLELVKDYGWLTIIAKPLFWLLEKIHKLLGNWGWSIVALTVLVKLVFFPLSATSYRSMAKMKDLQPRMT
AIRERHKGDPQKMNQEMMTLYRTEKVNPLGGCLPIVIQIPVFIALYWVLLSSVEMRGAPWLGWVHDLASPDPFYILPILM
AVSMFVQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYWVVNNCLSIAQQWSINRMLGTNKKAAAAK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=506, Percent_Identity=38.7351778656126, Blast_Score=356, Evalue=2e-99,
Organism=Drosophila melanogaster, GI24662345, Length=193, Percent_Identity=28.4974093264249, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21356443, Length=193, Percent_Identity=28.4974093264249, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_RALSO (Q8Y3H6)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_518125.1
- ProteinModelPortal:   Q8Y3H6
- SMR:   Q8Y3H6
- GeneID:   1218806
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0004
- NMPDR:   fig|267608.1.peg.4
- HOGENOM:   HBG507812
- OMA:   NVEKEAF
- ProtClustDB:   PRK01318
- BioCyc:   RSOL267608:RSC0004-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 60628; Mature: 60628

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xbca00cc)-; HASH(0xbca030c)-; HASH(0xbca9528)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKRTILWVIFSLSVVLLFDNWQRANGHQSMFFPTPQTVTTTAAAPGGTPAGDVPKAAA
CCHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCC
PAAAGSQAAPATGAVSQTPASEKIVVTTDVIRATVDTAGAIVTKLELLTQKDHDGNPMVL
CCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
FDRSLERTYLARSGLIGGDFPNHTTVFTASAGPRDLGTGGEVSLTLTADKGGAKLAKTYV
EECCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHH
FKRGSYVIDTRFDVTNDGAAPINPTLYMELARDGGAVEQSRFYSTFTGPAVYTDTDHYHK
EECCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHEECCCCEEECCCCCEEE
ITFADIDKSKAHVPAPTDSGWVAMVQHYFASAWIPAASAKREFYVDRIDTNFYRVGMQQA
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHEEEEHHCCHHHHHHHHHH
LGTVAPGASVSATARLFAGPQEERMLEGITPGLELVKDYGWLTIIAKPLFWLLEKIHKLL
HHHCCCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GNWGWSIVALTVLVKLVFFPLSATSYRSMAKMKDLQPRMTAIRERHKGDPQKMNQEMMTL
HCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
YRTEKVNPLGGCLPIVIQIPVFIALYWVLLSSVEMRGAPWLGWVHDLASPDPFYILPILM
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHH
AVSMFVQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYWVVNNCLSIAQQWSIN
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
RMLGTNKKAAAAK
HHHCCCCHHCCCH
>Mature Secondary Structure
MDIKRTILWVIFSLSVVLLFDNWQRANGHQSMFFPTPQTVTTTAAAPGGTPAGDVPKAAA
CCHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCC
PAAAGSQAAPATGAVSQTPASEKIVVTTDVIRATVDTAGAIVTKLELLTQKDHDGNPMVL
CCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
FDRSLERTYLARSGLIGGDFPNHTTVFTASAGPRDLGTGGEVSLTLTADKGGAKLAKTYV
EECCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHH
FKRGSYVIDTRFDVTNDGAAPINPTLYMELARDGGAVEQSRFYSTFTGPAVYTDTDHYHK
EECCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHEECCCCEEECCCCCEEE
ITFADIDKSKAHVPAPTDSGWVAMVQHYFASAWIPAASAKREFYVDRIDTNFYRVGMQQA
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHEEEEHHCCHHHHHHHHHH
LGTVAPGASVSATARLFAGPQEERMLEGITPGLELVKDYGWLTIIAKPLFWLLEKIHKLL
HHHCCCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GNWGWSIVALTVLVKLVFFPLSATSYRSMAKMKDLQPRMTAIRERHKGDPQKMNQEMMTL
HCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
YRTEKVNPLGGCLPIVIQIPVFIALYWVLLSSVEMRGAPWLGWVHDLASPDPFYILPILM
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHH
AVSMFVQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYWVVNNCLSIAQQWSIN
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
RMLGTNKKAAAAK
HHHCCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852