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The map label for this gene is tig [H]

Identifier: 17231173

GI number: 17231173

Start: 4440005

End: 4441420

Strand: Direct

Name: tig [H]

Synonym: alr3681

Alternate gene names: 17231173

Gene position: 4440005-4441420 (Clockwise)

Preceding gene: 17231168

Following gene: 17231175

Centisome position: 69.23

GC content: 44.42

Gene sequence:

>1416_bases
ATGAAAGTTACCCAGGAAAAACTTCCCGCCAGCCAAATTGGTCTGGAAATAGAGATTACACCAGAAATTACGCAAAAAAC
TTACGAACAGGTAATTAAAAATTTATCCAGAACCGTTAACATTCCTGGGTTTCGTAAAGGCAAAGTACCAAGACAAGTAT
TATTACAGCGTCTAGGTAAAACTCACATCAAAGCCGCAGCCCTGGAAGAATTGCTGCAAGATGGGATAGAGCAAGCAATC
AAGCAAGAATCCATTGCCGCAATTGGTCAACCACGCCTGCGCTCATCCTTCGATGATTTAATTAATAGTTACGAACCAGG
ACAGCCCTTGACTTTTACTGCGGCTGTGGATGTAGAACCAGAAATCAACCTAGTGCAGTACACAGGTTTAGAAGCCAAAG
CCGAAGAAATCAAGTACGATCCAGCGCGGGTTGATGAAGTTTTAGAAAAAGAACGTCAAGAATTGGCGACATTAATTCCC
GTAGAAGGAAGATCCGCCCAAATTGGTGACGTGGCTGTAGTGGACTTTAAAGGTGTAATCGCCAAAGCTGAAGGTGATGA
CGAAAATGCCGAACCCGAACCCATTCCTGGCGGTGACGCTAGCGATTTTCAGGTAGAATTACAGGAAGATAGATTTATTC
CTGGTTTTGTGACTGGCATCGTGGGCATGAATCCAGGGGACACCAAAGAAGTGTCAGCTCAATTCCCAGACCCTTACGTT
AACCAAGAATTGGCAGGGAAACCGGCAATTTTTACGGTGACTCTCAAAGAAATTAAAGAAAAAGAACTACCGGAATTAAA
TGACGACTTTGCCCAAGAAGTCAGCGATTTCGATACTCTAGAAGCGTTGCGCGCTTCTTTGGCAGAGCGTTATCAAAAAG
AAGCGGAAGACAAAACCAAGAATAATCAGCAAGAGGCTTTGTTAGGCGAACTAGTTAAGCACATAGAAGTAGATTTGCCA
GAAACCCTGATTGAGAAAGAAGTAGACGCGATGCTGACACAAACAGCTATGCGCCTATCCCAACAGGGACTGGATGTGAA
AAAATTATTCACCCAGGATATTATCCCGCAGTTACGGGAGCGATCGCGCCCTGAGGCTGTAGAACGCCTTAAACGGTCTT
TGGGTTTGCAAGAAGTCGCTAAACGCGAGTCAATTACCGTCACCCCAGAAGAAATTCAAGCCAGAGTGACAGAATTGGTG
CAACAATACCCAGACGAAGACATTGATGCAGAAAGATTGCAAACCATCGTAGAAAACGAGCTATTATCCGAAAAAATCAT
TGATTGGCTATTAGCAAATTCTACCGTTGAACTGGTACCAGAAGGCTCATTAGCTAGCCAAGAGCCAGAGATAACTGCAC
CTGAGACTGAGGCAGAAACCATAGAGGTTGCAGCAGAATCGACTACAGGGGAATAA

Upstream 100 bases:

>100_bases
TCTTGCTCAGAATTGAGAACTCAAAATCCGGCACTCATTTTGGTTAATCGCATCTTGTATGTACTTGGAGTCACAAACCC
CCAAAATTTAGAGACGAAGC

Downstream 100 bases:

>100_bases
AAAGGCAATTTTGTAGCGACTGTCTTGAAAGTCAAGCGATCGTTAACAAAAACCGGGACTCTGAACATTGACGCAACTGG
GGAACGCTGCGCTAGATTCT

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKVTQEKLPASQIGLEIEITPEITQKTYEQVIKNLSRTVNIPGFRKGKVPRQVLLQRLGKTHIKAAALEELLQDGIEQAI
KQESIAAIGQPRLRSSFDDLINSYEPGQPLTFTAAVDVEPEINLVQYTGLEAKAEEIKYDPARVDEVLEKERQELATLIP
VEGRSAQIGDVAVVDFKGVIAKAEGDDENAEPEPIPGGDASDFQVELQEDRFIPGFVTGIVGMNPGDTKEVSAQFPDPYV
NQELAGKPAIFTVTLKEIKEKELPELNDDFAQEVSDFDTLEALRASLAERYQKEAEDKTKNNQQEALLGELVKHIEVDLP
ETLIEKEVDAMLTQTAMRLSQQGLDVKKLFTQDIIPQLRERSRPEAVERLKRSLGLQEVAKRESITVTPEEIQARVTELV
QQYPDEDIDAERLQTIVENELLSEKIIDWLLANSTVELVPEGSLASQEPEITAPETEAETIEVAAESTTGE

Sequences:

>Translated_471_residues
MKVTQEKLPASQIGLEIEITPEITQKTYEQVIKNLSRTVNIPGFRKGKVPRQVLLQRLGKTHIKAAALEELLQDGIEQAI
KQESIAAIGQPRLRSSFDDLINSYEPGQPLTFTAAVDVEPEINLVQYTGLEAKAEEIKYDPARVDEVLEKERQELATLIP
VEGRSAQIGDVAVVDFKGVIAKAEGDDENAEPEPIPGGDASDFQVELQEDRFIPGFVTGIVGMNPGDTKEVSAQFPDPYV
NQELAGKPAIFTVTLKEIKEKELPELNDDFAQEVSDFDTLEALRASLAERYQKEAEDKTKNNQQEALLGELVKHIEVDLP
ETLIEKEVDAMLTQTAMRLSQQGLDVKKLFTQDIIPQLRERSRPEAVERLKRSLGLQEVAKRESITVTPEEIQARVTELV
QQYPDEDIDAERLQTIVENELLSEKIIDWLLANSTVELVPEGSLASQEPEITAPETEAETIEVAAESTTGE
>Mature_471_residues
MKVTQEKLPASQIGLEIEITPEITQKTYEQVIKNLSRTVNIPGFRKGKVPRQVLLQRLGKTHIKAAALEELLQDGIEQAI
KQESIAAIGQPRLRSSFDDLINSYEPGQPLTFTAAVDVEPEINLVQYTGLEAKAEEIKYDPARVDEVLEKERQELATLIP
VEGRSAQIGDVAVVDFKGVIAKAEGDDENAEPEPIPGGDASDFQVELQEDRFIPGFVTGIVGMNPGDTKEVSAQFPDPYV
NQELAGKPAIFTVTLKEIKEKELPELNDDFAQEVSDFDTLEALRASLAERYQKEAEDKTKNNQQEALLGELVKHIEVDLP
ETLIEKEVDAMLTQTAMRLSQQGLDVKKLFTQDIIPQLRERSRPEAVERLKRSLGLQEVAKRESITVTPEEIQARVTELV
QQYPDEDIDAERLQTIVENELLSEKIIDWLLANSTVELVPEGSLASQEPEITAPETEAETIEVAAESTTGE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=437, Percent_Identity=28.3752860411899, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 52383; Mature: 52383

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTQEKLPASQIGLEIEITPEITQKTYEQVIKNLSRTVNIPGFRKGKVPRQVLLQRLGK
CCCCHHHCCHHHCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCH
THIKAAALEELLQDGIEQAIKQESIAAIGQPRLRSSFDDLINSYEPGQPLTFTAAVDVEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCC
EINLVQYTGLEAKAEEIKYDPARVDEVLEKERQELATLIPVEGRSAQIGDVAVVDFKGVI
CCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEE
AKAEGDDENAEPEPIPGGDASDFQVELQEDRFIPGFVTGIVGMNPGDTKEVSAQFPDPYV
EECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCHHCCCCCCCCC
NQELAGKPAIFTVTLKEIKEKELPELNDDFAQEVSDFDTLEALRASLAERYQKEAEDKTK
CHHHCCCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NNQQEALLGELVKHIEVDLPETLIEKEVDAMLTQTAMRLSQQGLDVKKLFTQDIIPQLRE
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RSRPEAVERLKRSLGLQEVAKRESITVTPEEIQARVTELVQQYPDEDIDAERLQTIVENE
CCCHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LLSEKIIDWLLANSTVELVPEGSLASQEPEITAPETEAETIEVAAESTTGE
HHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCC
>Mature Secondary Structure
MKVTQEKLPASQIGLEIEITPEITQKTYEQVIKNLSRTVNIPGFRKGKVPRQVLLQRLGK
CCCCHHHCCHHHCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCH
THIKAAALEELLQDGIEQAIKQESIAAIGQPRLRSSFDDLINSYEPGQPLTFTAAVDVEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCC
EINLVQYTGLEAKAEEIKYDPARVDEVLEKERQELATLIPVEGRSAQIGDVAVVDFKGVI
CCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEE
AKAEGDDENAEPEPIPGGDASDFQVELQEDRFIPGFVTGIVGMNPGDTKEVSAQFPDPYV
EECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCHHCCCCCCCCC
NQELAGKPAIFTVTLKEIKEKELPELNDDFAQEVSDFDTLEALRASLAERYQKEAEDKTK
CHHHCCCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NNQQEALLGELVKHIEVDLPETLIEKEVDAMLTQTAMRLSQQGLDVKKLFTQDIIPQLRE
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RSRPEAVERLKRSLGLQEVAKRESITVTPEEIQARVTELVQQYPDEDIDAERLQTIVENE
CCCHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LLSEKIIDWLLANSTVELVPEGSLASQEPEITAPETEAETIEVAAESTTGE
HHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA