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The map label for this gene is rfbB [C]

Identifier: 17228153

GI number: 17228153

Start: 761010

End: 761945

Strand: Direct

Name: rfbB [C]

Synonym: alr0657

Alternate gene names: 17228153

Gene position: 761010-761945 (Clockwise)

Preceding gene: 17228152

Following gene: 17228154

Centisome position: 11.87

GC content: 43.91

Gene sequence:

>936_bases
ATGAGAATTTTGGTGACTGGCGGTGCAGGATTTATTGGTTCTCATCTTATTGATCGGCTGATACCTCAAGGCCATGAAGT
TATTTGTTTAGATAACTTCTACACCGGCGACAAACGCAATATCCATAAATGGGCGAACCATCCCAATTTTGAACTTATCC
GCCATGATATAACCGAACCAATTAGGTTAGAAGTCGATCAGATTTATCATTTAGCTTGTCCAGCTTCCCCAGTACACTAT
CAGTACAACCCAGTCAAAACCGTTAAAACTAACGTGATGGGTACACTAAATATGTTAGGGTTAGCCAAACGTGTCAAGGC
GAGATTTTTCCTAGCGTCCACTAGTGAAGTATACGGTGACCCTGAGATCCATCCCCAAACAGAGGAGTACCGAGGTAATG
TTAACCCTATCGGTATCCGTTCTTGCTACGACGAAGGCAAAAGAATTGCGGAAACCCTGGCATTTGATTATTACAGACAA
AATAAAGTTGATATTCGAGTTGTCCGTATATTCAACACCTACGGCCCCAGGATGTTAGAAAACGACGGGCGGGTGGTGAG
TAATTTTATAGTTCAAGCTTTACGAGGCACACCTTTAACGGTGTACGGTGATGGCTCACAAACTCGGAGTTTTTGCTATG
TCTCAGACCTGGTGGAAGGCTTTATCCGCTTGATGAATAGCGATTACGTCGGGCCAGTCAATTTAGGAAATCCTGGTGAA
TACACCATTCTAGAATTAGCGCAAGCTGTGCAAAATTTGATCAATCCAGATGCACAGATCAAGTTTGAACCATTGCCTGC
TGATGATCCACGTCGTCGCCAACCAGATATTACAAAAGCCAGAACCTTGCTCAATTGGGAACCAACCATTCCTCTAGAAG
AAGGGTTAAAGCTGACGATAGAAGATTTCCGCGATCGCATCAAGAGTGCCGTCTAG

Upstream 100 bases:

>100_bases
GGAATGAGTATTGTTCCTGCTGTATTGTCATATTTGGGCTAGATGGTTTAGAACCAATATCAAAAGCTACTAACAATATC
TATTAAGTAACTGGGAAAAT

Downstream 100 bases:

>100_bases
GATACAGGCTACTTAGGAGCCTGGGGTACTGTTCTCAAATGCTAGCTAACTTTATTTGAGCAGGTATTTCGGCAACAGTA
CAGCATGAAAAAGTGTAAAT

Product: dTDP-glucose 4-6-dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRILVTGGAGFIGSHLIDRLIPQGHEVICLDNFYTGDKRNIHKWANHPNFELIRHDITEPIRLEVDQIYHLACPASPVHY
QYNPVKTVKTNVMGTLNMLGLAKRVKARFFLASTSEVYGDPEIHPQTEEYRGNVNPIGIRSCYDEGKRIAETLAFDYYRQ
NKVDIRVVRIFNTYGPRMLENDGRVVSNFIVQALRGTPLTVYGDGSQTRSFCYVSDLVEGFIRLMNSDYVGPVNLGNPGE
YTILELAQAVQNLINPDAQIKFEPLPADDPRRRQPDITKARTLLNWEPTIPLEEGLKLTIEDFRDRIKSAV

Sequences:

>Translated_311_residues
MRILVTGGAGFIGSHLIDRLIPQGHEVICLDNFYTGDKRNIHKWANHPNFELIRHDITEPIRLEVDQIYHLACPASPVHY
QYNPVKTVKTNVMGTLNMLGLAKRVKARFFLASTSEVYGDPEIHPQTEEYRGNVNPIGIRSCYDEGKRIAETLAFDYYRQ
NKVDIRVVRIFNTYGPRMLENDGRVVSNFIVQALRGTPLTVYGDGSQTRSFCYVSDLVEGFIRLMNSDYVGPVNLGNPGE
YTILELAQAVQNLINPDAQIKFEPLPADDPRRRQPDITKARTLLNWEPTIPLEEGLKLTIEDFRDRIKSAV
>Mature_311_residues
MRILVTGGAGFIGSHLIDRLIPQGHEVICLDNFYTGDKRNIHKWANHPNFELIRHDITEPIRLEVDQIYHLACPASPVHY
QYNPVKTVKTNVMGTLNMLGLAKRVKARFFLASTSEVYGDPEIHPQTEEYRGNVNPIGIRSCYDEGKRIAETLAFDYYRQ
NKVDIRVVRIFNTYGPRMLENDGRVVSNFIVQALRGTPLTVYGDGSQTRSFCYVSDLVEGFIRLMNSDYVGPVNLGNPGE
YTILELAQAVQNLINPDAQIKFEPLPADDPRRRQPDITKARTLLNWEPTIPLEEGLKLTIEDFRDRIKSAV

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=307, Percent_Identity=64.8208469055375, Blast_Score=437, Evalue=1e-123,
Organism=Homo sapiens, GI7657641, Length=327, Percent_Identity=29.0519877675841, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI4507709, Length=324, Percent_Identity=25.6172839506173, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1788589, Length=338, Percent_Identity=27.2189349112426, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=26.9461077844311, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786974, Length=328, Percent_Identity=28.3536585365854, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788353, Length=341, Percent_Identity=26.3929618768328, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17539532, Length=308, Percent_Identity=59.4155844155844, Blast_Score=397, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17568069, Length=330, Percent_Identity=29.0909090909091, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115532424, Length=328, Percent_Identity=27.1341463414634, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71982035, Length=332, Percent_Identity=26.2048192771084, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=24.6290801186944, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356223, Length=306, Percent_Identity=64.7058823529412, Blast_Score=426, Evalue=1e-120,
Organism=Drosophila melanogaster, GI19923002, Length=346, Percent_Identity=26.0115606936416, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35388; Mature: 35388

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTGGAGFIGSHLIDRLIPQGHEVICLDNFYTGDKRNIHKWANHPNFELIRHDITEP
CEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCCCCCHHHHHHHCCCC
IRLEVDQIYHLACPASPVHYQYNPVKTVKTNVMGTLNMLGLAKRVKARFFLASTSEVYGD
CEEEHHHEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHCCC
PEIHPQTEEYRGNVNPIGIRSCYDEGKRIAETLAFDYYRQNKVDIRVVRIFNTYGPRMLE
CCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEC
NDGRVVSNFIVQALRGTPLTVYGDGSQTRSFCYVSDLVEGFIRLMNSDYVGPVNLGNPGE
CCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
YTILELAQAVQNLINPDAQIKFEPLPADDPRRRQPDITKARTLLNWEPTIPLEEGLKLTI
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHEECCCCCCCHHHCCEEEH
EDFRDRIKSAV
HHHHHHHHHCC
>Mature Secondary Structure
MRILVTGGAGFIGSHLIDRLIPQGHEVICLDNFYTGDKRNIHKWANHPNFELIRHDITEP
CEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCCCCCHHHHHHHCCCC
IRLEVDQIYHLACPASPVHYQYNPVKTVKTNVMGTLNMLGLAKRVKARFFLASTSEVYGD
CEEEHHHEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHCCC
PEIHPQTEEYRGNVNPIGIRSCYDEGKRIAETLAFDYYRQNKVDIRVVRIFNTYGPRMLE
CCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEC
NDGRVVSNFIVQALRGTPLTVYGDGSQTRSFCYVSDLVEGFIRLMNSDYVGPVNLGNPGE
CCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
YTILELAQAVQNLINPDAQIKFEPLPADDPRRRQPDITKARTLLNWEPTIPLEEGLKLTI
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHEECCCCCCCHHHCCEEEH
EDFRDRIKSAV
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]