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The map label for this gene is kefC [C]

Identifier: 17228152

GI number: 17228152

Start: 758587

End: 760725

Strand: Direct

Name: kefC [C]

Synonym: alr0656

Alternate gene names: 17228152

Gene position: 758587-760725 (Clockwise)

Preceding gene: 17228151

Following gene: 17228153

Centisome position: 11.83

GC content: 42.17

Gene sequence:

>2139_bases
ATGGAACCCTCATCACTAGTTCTTGCTCTAGAACAAACTTCTGAAGTTCTTGGCAAAGAACCAATTGTTCCTTTCGCAAT
TTTACTGGTAGTCCTCTTAGTTGTACCCATCCTCTTTGAAAGGCTAAGATTACCAGGAATAGTGGGTTTAGTCCTCTCTG
GATTAGTCTTAGGTCCATCGGGGTGGAACCTATTCCATACAAAATCACCGATGATTAGCCTGCTATCAGATATTGGCTTA
GTTTATTTGATGTTTGTCGCAGGTCTAGAGGTAGATTTAGAATTGTGGCGGCGGCGGCAAAGACGTGCTTTAGGGTTTGG
CTGCGTTAGTTTTACTATACCGTTGTTGATTGGCACTTTAGTAGGAAGATTTTTTCACTTTGGTTGGAATACTTCCGTAT
TAATCGGCTCACTTTTAACTTCTTATAGTCTGTTAGCTTATCCTATTATCAACCGATTAGGTGTCATCAGTAACCAAGCA
GTCACAATTACAATTGGGGCTACAGTTTTTACAGATATTAGCGCACTTATAGTATTAGCTATTTGCATTCCAGCTTTTCA
AATGGGAATGTCAAATATTTACCAGATACTCTCCCTCTTAGGTTGGTTAATTATTTACTCGATCGTGATTTTAGTGGGAT
TTGATTGGGCTGGGAGAGAATTTTTTCGGCGTTCGGGAGACGATGAAGGTAACAAATTTTTATTTGTCTTACTCACCGTA
TTTCTAGCAGTTGTAGTAGCTCAACTGATTGGGATAGAAAAAATTCTGGGAGCTTTTTTAGCAGGTTTAGCAGTAAATGA
GGCTGTTGGTGAGGGGCCTGTTAAAGAAAAAATAGTTTTTGTTGGTAGTGTCTTATTTATTCCGATTTTTTTTATTAACC
TCGGCTTGCTGATTGACTTGCCTGGTTTAGTTAATAGTCTGTTTACTCTCCAGTTAACCAGTTTGATTGTTATCAGCTTG
GTTGCTAGCAAATTTATCGCCGCTTGGTTAGCTAAGGTGTTTTATGGCTACAGTTGGCAGGAAATGTTGACTATGTGGTC
GCTATCTATTCCCCAGGTTGGTACAACATTAGCTGCTACCTTCGTAGGGTATCACACAGGTTTACTTTCATCGGCAGTTT
TAACTAGTGTTGTGATCTTAATGTTAATCACTGCAACCTTAGGCCCATTGATTACTAGTCGCACCGCCAGAGCTTTAACT
ACCGTATCAATTACAGAATCGGTGGATGCAAATCTGCCTGAGCCACAGGTAATAGAAACCCAAAATGGTAACTTTACTAT
CGTTGTACCGATTTATAATCCCCATACTCAACAATATTTGGTGGAAATGGCAGCATTGCTAGCACATCAAGCTCAAGGGC
GAATCATACCATTAACGATCGCCACAGCTGCGGCTCATATGGATGCACCCCAACTAGAATCAACATTGCAAAGAAGTGAG
CGATTATTAGCCAAAGCCACCAGCCAAAGTCAAGCCTTGGGTGTAGCAGCCTCGCCATTACTCCGCATTGACGATGCTTC
TGCGCCGGGAATTAGTAGAGCAGCGCGTGAGCAAAAAGCCAATTTAATTGTTATGGGTTGGGGTAAACGGACTGGTTTAA
GAGCGCGGTTATTTGGCAATGTCATTGATAATGTTTTGTGGTCGTCCCATTGTCCAGTGGCGGTAACACGTCTTGTAGAA
TCACCCAAGAAAATTCAACGTATCCTAGTACCGGTGGAAAACTTAATCACACCAACATTACAGCCTGTACAATTTGCCCA
GATGTTAGCAGAAGCCAATCAAGCCCAAGTGACAGTGTTGAATGTGTGCGATCGCCGCACAAGTTCCAGTAAAATTGCTT
CTAGGCGATCGCAACTTGCTTTATTAGTATCTAAATTAGCTTTGCCCAACTCACCCGAAGTGCAAATTATTGCTCATGAA
AATGCTGCTCAAGCCATTTTGCAAGCAGCGCGATTATATGACCTAGTAGTTTTACCCTTTATCCGTAACCGAACAAGTCC
TGGAGGATTAGCTCTCAGCGATGTCACCACTCAGTTAGCCAGTCAACTCACCTGCTCCATCGTCATGTTAGGAGAACCGC
AACGCCTGCAAACAGGTAATATCACCTCTGTAGCTCCTAACACTACGACAGCAGTATAA

Upstream 100 bases:

>100_bases
TTTTATTTTTTACAGGGTAGCTTTCATAGTTATGTATGATTGATCGGACGATTACCTCAGGGTAATCCCCGCCTTCCCGT
CGCCCTTTCACATTCCACTT

Downstream 100 bases:

>100_bases
ACACCCCTACACCCTTACACCCCCATACCCTTAATTCCTGACAACGTACTCTAACAAGACTTTATTTTGTTGAAGATTTG
ATGAATTATTGATCAAAAGA

Product: Na+/H+ antiporter

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: MjNapA [H]

Number of amino acids: Translated: 712; Mature: 712

Protein sequence:

>712_residues
MEPSSLVLALEQTSEVLGKEPIVPFAILLVVLLVVPILFERLRLPGIVGLVLSGLVLGPSGWNLFHTKSPMISLLSDIGL
VYLMFVAGLEVDLELWRRRQRRALGFGCVSFTIPLLIGTLVGRFFHFGWNTSVLIGSLLTSYSLLAYPIINRLGVISNQA
VTITIGATVFTDISALIVLAICIPAFQMGMSNIYQILSLLGWLIIYSIVILVGFDWAGREFFRRSGDDEGNKFLFVLLTV
FLAVVVAQLIGIEKILGAFLAGLAVNEAVGEGPVKEKIVFVGSVLFIPIFFINLGLLIDLPGLVNSLFTLQLTSLIVISL
VASKFIAAWLAKVFYGYSWQEMLTMWSLSIPQVGTTLAATFVGYHTGLLSSAVLTSVVILMLITATLGPLITSRTARALT
TVSITESVDANLPEPQVIETQNGNFTIVVPIYNPHTQQYLVEMAALLAHQAQGRIIPLTIATAAAHMDAPQLESTLQRSE
RLLAKATSQSQALGVAASPLLRIDDASAPGISRAAREQKANLIVMGWGKRTGLRARLFGNVIDNVLWSSHCPVAVTRLVE
SPKKIQRILVPVENLITPTLQPVQFAQMLAEANQAQVTVLNVCDRRTSSSKIASRRSQLALLVSKLALPNSPEVQIIAHE
NAAQAILQAARLYDLVVLPFIRNRTSPGGLALSDVTTQLASQLTCSIVMLGEPQRLQTGNITSVAPNTTTAV

Sequences:

>Translated_712_residues
MEPSSLVLALEQTSEVLGKEPIVPFAILLVVLLVVPILFERLRLPGIVGLVLSGLVLGPSGWNLFHTKSPMISLLSDIGL
VYLMFVAGLEVDLELWRRRQRRALGFGCVSFTIPLLIGTLVGRFFHFGWNTSVLIGSLLTSYSLLAYPIINRLGVISNQA
VTITIGATVFTDISALIVLAICIPAFQMGMSNIYQILSLLGWLIIYSIVILVGFDWAGREFFRRSGDDEGNKFLFVLLTV
FLAVVVAQLIGIEKILGAFLAGLAVNEAVGEGPVKEKIVFVGSVLFIPIFFINLGLLIDLPGLVNSLFTLQLTSLIVISL
VASKFIAAWLAKVFYGYSWQEMLTMWSLSIPQVGTTLAATFVGYHTGLLSSAVLTSVVILMLITATLGPLITSRTARALT
TVSITESVDANLPEPQVIETQNGNFTIVVPIYNPHTQQYLVEMAALLAHQAQGRIIPLTIATAAAHMDAPQLESTLQRSE
RLLAKATSQSQALGVAASPLLRIDDASAPGISRAAREQKANLIVMGWGKRTGLRARLFGNVIDNVLWSSHCPVAVTRLVE
SPKKIQRILVPVENLITPTLQPVQFAQMLAEANQAQVTVLNVCDRRTSSSKIASRRSQLALLVSKLALPNSPEVQIIAHE
NAAQAILQAARLYDLVVLPFIRNRTSPGGLALSDVTTQLASQLTCSIVMLGEPQRLQTGNITSVAPNTTTAV
>Mature_712_residues
MEPSSLVLALEQTSEVLGKEPIVPFAILLVVLLVVPILFERLRLPGIVGLVLSGLVLGPSGWNLFHTKSPMISLLSDIGL
VYLMFVAGLEVDLELWRRRQRRALGFGCVSFTIPLLIGTLVGRFFHFGWNTSVLIGSLLTSYSLLAYPIINRLGVISNQA
VTITIGATVFTDISALIVLAICIPAFQMGMSNIYQILSLLGWLIIYSIVILVGFDWAGREFFRRSGDDEGNKFLFVLLTV
FLAVVVAQLIGIEKILGAFLAGLAVNEAVGEGPVKEKIVFVGSVLFIPIFFINLGLLIDLPGLVNSLFTLQLTSLIVISL
VASKFIAAWLAKVFYGYSWQEMLTMWSLSIPQVGTTLAATFVGYHTGLLSSAVLTSVVILMLITATLGPLITSRTARALT
TVSITESVDANLPEPQVIETQNGNFTIVVPIYNPHTQQYLVEMAALLAHQAQGRIIPLTIATAAAHMDAPQLESTLQRSE
RLLAKATSQSQALGVAASPLLRIDDASAPGISRAAREQKANLIVMGWGKRTGLRARLFGNVIDNVLWSSHCPVAVTRLVE
SPKKIQRILVPVENLITPTLQPVQFAQMLAEANQAQVTVLNVCDRRTSSSKIASRRSQLALLVSKLALPNSPEVQIIAHE
NAAQAILQAARLYDLVVLPFIRNRTSPGGLALSDVTTQLASQLTCSIVMLGEPQRLQTGNITSVAPNTTTAV

Specific function: This is probably a Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Escherichia coli, GI1786232, Length=292, Percent_Identity=28.4246575342466, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322367, Length=391, Percent_Identity=25.5754475703325, Blast_Score=101, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 76962; Mature: 76962

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPSSLVLALEQTSEVLGKEPIVPFAILLVVLLVVPILFERLRLPGIVGLVLSGLVLGPS
CCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEECCC
GWNLFHTKSPMISLLSDIGLVYLMFVAGLEVDLELWRRRQRRALGFGCVSFTIPLLIGTL
CCCCEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGRFFHFGWNTSVLIGSLLTSYSLLAYPIINRLGVISNQAVTITIGATVFTDISALIVLA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHH
ICIPAFQMGMSNIYQILSLLGWLIIYSIVILVGFDWAGREFFRRSGDDEGNKFLFVLLTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHH
FLAVVVAQLIGIEKILGAFLAGLAVNEAVGEGPVKEKIVFVGSVLFIPIFFINLGLLIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGLVNSLFTLQLTSLIVISLVASKFIAAWLAKVFYGYSWQEMLTMWSLSIPQVGTTLAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
FVGYHTGLLSSAVLTSVVILMLITATLGPLITSRTARALTTVSITESVDANLPEPQVIET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHCCCCCCCCCEEEE
QNGNFTIVVPIYNPHTQQYLVEMAALLAHQAQGRIIPLTIATAAAHMDAPQLESTLQRSE
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCHHHHHHHHHHH
RLLAKATSQSQALGVAASPLLRIDDASAPGISRAAREQKANLIVMGWGKRTGLRARLFGN
HHHHHHCCHHHHCCHHCCCCEEECCCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHH
VIDNVLWSSHCPVAVTRLVESPKKIQRILVPVENLITPTLQPVQFAQMLAEANQAQVTVL
HHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEE
NVCDRRTSSSKIASRRSQLALLVSKLALPNSPEVQIIAHENAAQAILQAARLYDLVVLPF
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
IRNRTSPGGLALSDVTTQLASQLTCSIVMLGEPQRLQTGNITSVAPNTTTAV
HHCCCCCCCEEHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEECCCCCCCC
>Mature Secondary Structure
MEPSSLVLALEQTSEVLGKEPIVPFAILLVVLLVVPILFERLRLPGIVGLVLSGLVLGPS
CCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEECCC
GWNLFHTKSPMISLLSDIGLVYLMFVAGLEVDLELWRRRQRRALGFGCVSFTIPLLIGTL
CCCCEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGRFFHFGWNTSVLIGSLLTSYSLLAYPIINRLGVISNQAVTITIGATVFTDISALIVLA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHH
ICIPAFQMGMSNIYQILSLLGWLIIYSIVILVGFDWAGREFFRRSGDDEGNKFLFVLLTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHH
FLAVVVAQLIGIEKILGAFLAGLAVNEAVGEGPVKEKIVFVGSVLFIPIFFINLGLLIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGLVNSLFTLQLTSLIVISLVASKFIAAWLAKVFYGYSWQEMLTMWSLSIPQVGTTLAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
FVGYHTGLLSSAVLTSVVILMLITATLGPLITSRTARALTTVSITESVDANLPEPQVIET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHCCCCCCCCCEEEE
QNGNFTIVVPIYNPHTQQYLVEMAALLAHQAQGRIIPLTIATAAAHMDAPQLESTLQRSE
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCHHHHHHHHHHH
RLLAKATSQSQALGVAASPLLRIDDASAPGISRAAREQKANLIVMGWGKRTGLRARLFGN
HHHHHHCCHHHHCCHHCCCCEEECCCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHH
VIDNVLWSSHCPVAVTRLVESPKKIQRILVPVENLITPTLQPVQFAQMLAEANQAQVTVL
HHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEE
NVCDRRTSSSKIASRRSQLALLVSKLALPNSPEVQIIAHENAAQAILQAARLYDLVVLPF
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
IRNRTSPGGLALSDVTTQLASQLTCSIVMLGEPQRLQTGNITSVAPNTTTAV
HHCCCCCCCEEHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]