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The map label for this gene is metH [H]

Identifier: 17227804

GI number: 17227804

Start: 350779

End: 354315

Strand: Direct

Name: metH [H]

Synonym: alr0308

Alternate gene names: 17227804

Gene position: 350779-354315 (Clockwise)

Preceding gene: 17227800

Following gene: 17227805

Centisome position: 5.47

GC content: 45.55

Gene sequence:

>3537_bases
ATGACTCATCCTTTCCTGAAACGCCTGCACAGTCCGGAACTTCCGGTTATCGTCTTCGACGGTGCAATGGGAACTAACCT
ACAAACCCAAAACCTCACGGCTGAGGATTTCGGCGGTGTGCAGTATGAAGGTTGTAACGAATACCTAGTCCACACCAAAC
CCGAAGCTGTCGCCAAGGTTCACCGCGACTTTCTCGCTGTGGGTGCAGATGTCATCGAAACCGACACTTTCGGTGCGACA
TCCATTGTTTTGGCGGAATATGACTTAGCAGACCAAACATATTACCTGAACAAGAAAGCCGCCGAACTGGCGAAAAGTGT
CGCTGCTGAATTTTCCACACCAGATAAACCCCGGTTTGTTGCTGGTTCCATCGGCCCCACAACCAAACTTCCCACCTTGG
GACATATCGACTTTGACACTCTCAAAACTTGCTTTGCTGAACAAGCAGAAGCGCTGTTAGATGGTGGCGTGGATTTACTT
TTGGTGGAGACTTGTCAAGATGTGCTGCAAATCAAAGCGGCGCTGAATGGGATAGAAGAAGTCTTTGGCAAGAGAGGGGA
ACGCATACCCTTGATGGTGTCCGTGACAATGGAAAGCATGGGGACAATGTTGGTCGGTTCCGAAATCAACGCCGTCCTGA
CAATTTTAGAACCTTTCCCAATTGACATTCTCGGTCTGAACTGTGCCACAGGCCCAGACTTGATGAAACCACATATTAAA
TATTTGGCTGAACATTCGCCGTTTGTGGTTTCTTGTATTCCTAACGCGGGTTTACCAGAAAACGTTGGTGGTCAAGCACA
TTATCGCTTAACACCAATGGAATTACGCATGGCGTTGATGCACTTTGTTGAAGATTTGGGTGTCCAAGTGATCGGGGGTT
GCTGTGGGACACGTCCAGAACACATTCAACAATTAGCAGAAATTGCCAAGGATTTAAAGCCAAAGGTGAGACAGCCAAGT
TTAGAACCTGCGGCTGCATCAATATATAGTACTCAACCCTACGAACAAGATAATTCTTTCTTGATTGTGGGTGAACGCCT
CAACGCCAGTGGTTCCAAGAAATGCCGTGATTTGCTGAATGCGGAAGATTGGGACGGATTGGTATCAATGGCGCGATCGC
AAGTCAAGGAAGGCGCACATATCCTTGATGTCAACGTTGATTATGTGGGACGGGACGGTGTGCGGGATATGCACGAACTA
GTTTCCCGCATTGTGAATAATGTTACACTCCCCTTAATGCTCGACTCCACCGAATGGGAAAAGATGGAGGCGGGTTTAAA
GGTGGCTGGTGGTAAGTGTTTGCTGAACTCCACCAACTACGAAGATGGGGAACCACGTTTCTTAAAAGTGTTGGAGTTGG
CGAAGAAATATGGCGCGGGTGTTGTTATTGGCACAATTGACGAAGAAGGGATGGCGCGGACAGCCGAGAAAAAGTTTCAA
ATTGCCCAGCGTGCCTATCGTCAATCGGTAGAATATGGGATTCCCCCCACAGAAATATTCTTTGATACCTTAGCTTTACC
AATTTCTACCGGGATTGAAGAAGACCGGGAAAATGGCAAGGCGACAATTGAATCAATTAGCCGTATCCGTAAAGAATTGC
CAGGGTGTCATGTTATTTTAGGCGTGTCAAATATATCCTTTGGCTTAAATTCAGCCTCGCGGATGGTCTTAAACTCCGTG
TTTCTCCATGAAGCAATGACTGCTGGCATGGATGCGGCGATCGTCAGTGCTAGCAAGATTCTACCACTGTCGAAGATTGA
AGAGCGTCATCAAGAAGTCTGCCGCCAGTTAATTTATGACCAGCGTAAATTTGAGGGTGATATCTGCATCTATGACCCCT
TAACAGAACTAACTAAATTGTTTGAGGGAGTCACCACCAAACGTAACAAAGGCGTTGATGAAAGCTTACCCATCGAAGAA
CGACTCAAGCGTCACATTATCGACGGCGAACGCATTGGTTTAGAAGCGCAACTGACAAAAGCCTTAGAACAATATCCACC
CCTAGAAATTATCAACACTTTCCTACTAGATGGGATGAAAGTAGTCGGGGAATTGTTCGGTTCAGGACAAATGCAGCTAC
CTTTCGTTTTACAGTCAGCCGAAACCATGAAAGCGGCGGTAGCCTACCTAGAACCGTTCATGGAAAAATCGGAAAGTGGC
AACAATGCCAAAGGTAAAGTAATTATTGCCACCGTGAAAGGCGATGTTCACGACATTGGTAAAAACCTAGTAGACATTAT
CTTGTCCAACAACGGCTACAAGGTAATTAACCTGGGAATTAAACAGCCGGTGGAAAATATCATCGAGGCTTACAACCAAC
ACAAAGCTGATTGTATTGCCATGAGTGGCTTGCTGGTAAAATCCACCGCATTCATGAAAGAAAATTTGGAGGTCTTCAAC
GAAAAAGGCATTAATGTTCCTGTAATTTTAGGTGGTGCGGCATTAACCCCGAAATTCGTGCATAAAGATTGCCAAAATAC
CTACAAAGGTAAAGTCATTTATGGCAAAGATGCTTTCTCAGACCTGCATTTCATGGATAAATTAATGCCAGCCAAAGCCA
CTGGCAAATGGGACAATTCCTTAGGATTCTTGGATGAAGTAGAAACCGAGGAAACAGAACCTACCAATCACAAATCCCCA
ATCCCCAGTCCCCAATCCCCAGTCCCCAGTCCCCAGTCCCCAGTCCCTATAGACACCCGACGTTCCGAAGCTGTAGCCAT
AGACATTCCCCGTCCCACACCACCATTCTGGGGAACGCAATTATTACAGCCTAGCGATATTTCCTTAGAGGAAATATTCT
GGCACATGGATTTGCAAGCCTTGATTGCGGGACAATGGCAATTCCGCAAACCCAAAGAACAATCAAAGGAAGAATATCAA
GCTTTCTTGAATGAGAAAGTGTATCCAGTTCTAGAAACTTGGAAACAGCGCATCATTGCAGAAAACTTGTTACATCCCCA
GGTAATTTATGGGTATTTTCCTTGTCAATCTGAGGGTAATACTTTATATGTTTACGAAACAAACAGCCCAAATGCCACAG
AAATCACTCAGTTTGAATTCCCCCGACAAAAGTCATCAAAACGATTATGTATTGCCGATTTCTTTGCACCGAAAGATTCA
GGAATCATTGATGTCTTCCCCATGCAGGCGGTGACTGTAGGCGAAATTGCTACAGAGTTCGCGCAAAAATTGTTTGCAAA
CAATCAATACACTGATTATCTGTATTTTCACGGTTTGGCGGTGCAAGTAGCAGAAGCCTTGGCCGAGTGGACACACGCCA
GAATCCGCCGTGAGTTAGGGTTCGGTGCTGAAGAACCGGATAATATCCGGGATATTTTGGCACAACGCTATCAGGGTTCC
CGGTATAGTTTTGGCTACCCAGCTTGTCCCAATATTCAAGACCAGTTTAAGCAGCTGGATTTGTTGGAGACTAGCAGAAT
TAACTTATACATGGATGAAAGTGAGCAACTTTATCCAGAACAGTCTACGACGGCGATTATTACTTATCACCCAGTAGCTA
AGTACTTCACCGCGTAA

Upstream 100 bases:

>100_bases
CCAATACTCAGCATACGAAACTCTGGCAATTATGGAAAATAATATATGTAAGTCGAGTATCGTAAGACTCACTTGATTTC
CTCATTTCCTCTAGGAAAAT

Downstream 100 bases:

>100_bases
TCCCAGTTTTCTCCTCCTCCTGTGTCTACCCCATAAATGTATGAGGAGGAGAATTTGGTCAAAAATATCTGTCACTGTTA
TATGAAGAACCTACACTTGT

Product: 5-methyltetrahydrofolate--homocysteine S-methyltransferase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1178; Mature: 1177

Protein sequence:

>1178_residues
MTHPFLKRLHSPELPVIVFDGAMGTNLQTQNLTAEDFGGVQYEGCNEYLVHTKPEAVAKVHRDFLAVGADVIETDTFGAT
SIVLAEYDLADQTYYLNKKAAELAKSVAAEFSTPDKPRFVAGSIGPTTKLPTLGHIDFDTLKTCFAEQAEALLDGGVDLL
LVETCQDVLQIKAALNGIEEVFGKRGERIPLMVSVTMESMGTMLVGSEINAVLTILEPFPIDILGLNCATGPDLMKPHIK
YLAEHSPFVVSCIPNAGLPENVGGQAHYRLTPMELRMALMHFVEDLGVQVIGGCCGTRPEHIQQLAEIAKDLKPKVRQPS
LEPAAASIYSTQPYEQDNSFLIVGERLNASGSKKCRDLLNAEDWDGLVSMARSQVKEGAHILDVNVDYVGRDGVRDMHEL
VSRIVNNVTLPLMLDSTEWEKMEAGLKVAGGKCLLNSTNYEDGEPRFLKVLELAKKYGAGVVIGTIDEEGMARTAEKKFQ
IAQRAYRQSVEYGIPPTEIFFDTLALPISTGIEEDRENGKATIESISRIRKELPGCHVILGVSNISFGLNSASRMVLNSV
FLHEAMTAGMDAAIVSASKILPLSKIEERHQEVCRQLIYDQRKFEGDICIYDPLTELTKLFEGVTTKRNKGVDESLPIEE
RLKRHIIDGERIGLEAQLTKALEQYPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPFMEKSESG
NNAKGKVIIATVKGDVHDIGKNLVDIILSNNGYKVINLGIKQPVENIIEAYNQHKADCIAMSGLLVKSTAFMKENLEVFN
EKGINVPVILGGAALTPKFVHKDCQNTYKGKVIYGKDAFSDLHFMDKLMPAKATGKWDNSLGFLDEVETEETEPTNHKSP
IPSPQSPVPSPQSPVPIDTRRSEAVAIDIPRPTPPFWGTQLLQPSDISLEEIFWHMDLQALIAGQWQFRKPKEQSKEEYQ
AFLNEKVYPVLETWKQRIIAENLLHPQVIYGYFPCQSEGNTLYVYETNSPNATEITQFEFPRQKSSKRLCIADFFAPKDS
GIIDVFPMQAVTVGEIATEFAQKLFANNQYTDYLYFHGLAVQVAEALAEWTHARIRRELGFGAEEPDNIRDILAQRYQGS
RYSFGYPACPNIQDQFKQLDLLETSRINLYMDESEQLYPEQSTTAIITYHPVAKYFTA

Sequences:

>Translated_1178_residues
MTHPFLKRLHSPELPVIVFDGAMGTNLQTQNLTAEDFGGVQYEGCNEYLVHTKPEAVAKVHRDFLAVGADVIETDTFGAT
SIVLAEYDLADQTYYLNKKAAELAKSVAAEFSTPDKPRFVAGSIGPTTKLPTLGHIDFDTLKTCFAEQAEALLDGGVDLL
LVETCQDVLQIKAALNGIEEVFGKRGERIPLMVSVTMESMGTMLVGSEINAVLTILEPFPIDILGLNCATGPDLMKPHIK
YLAEHSPFVVSCIPNAGLPENVGGQAHYRLTPMELRMALMHFVEDLGVQVIGGCCGTRPEHIQQLAEIAKDLKPKVRQPS
LEPAAASIYSTQPYEQDNSFLIVGERLNASGSKKCRDLLNAEDWDGLVSMARSQVKEGAHILDVNVDYVGRDGVRDMHEL
VSRIVNNVTLPLMLDSTEWEKMEAGLKVAGGKCLLNSTNYEDGEPRFLKVLELAKKYGAGVVIGTIDEEGMARTAEKKFQ
IAQRAYRQSVEYGIPPTEIFFDTLALPISTGIEEDRENGKATIESISRIRKELPGCHVILGVSNISFGLNSASRMVLNSV
FLHEAMTAGMDAAIVSASKILPLSKIEERHQEVCRQLIYDQRKFEGDICIYDPLTELTKLFEGVTTKRNKGVDESLPIEE
RLKRHIIDGERIGLEAQLTKALEQYPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPFMEKSESG
NNAKGKVIIATVKGDVHDIGKNLVDIILSNNGYKVINLGIKQPVENIIEAYNQHKADCIAMSGLLVKSTAFMKENLEVFN
EKGINVPVILGGAALTPKFVHKDCQNTYKGKVIYGKDAFSDLHFMDKLMPAKATGKWDNSLGFLDEVETEETEPTNHKSP
IPSPQSPVPSPQSPVPIDTRRSEAVAIDIPRPTPPFWGTQLLQPSDISLEEIFWHMDLQALIAGQWQFRKPKEQSKEEYQ
AFLNEKVYPVLETWKQRIIAENLLHPQVIYGYFPCQSEGNTLYVYETNSPNATEITQFEFPRQKSSKRLCIADFFAPKDS
GIIDVFPMQAVTVGEIATEFAQKLFANNQYTDYLYFHGLAVQVAEALAEWTHARIRRELGFGAEEPDNIRDILAQRYQGS
RYSFGYPACPNIQDQFKQLDLLETSRINLYMDESEQLYPEQSTTAIITYHPVAKYFTA
>Mature_1177_residues
THPFLKRLHSPELPVIVFDGAMGTNLQTQNLTAEDFGGVQYEGCNEYLVHTKPEAVAKVHRDFLAVGADVIETDTFGATS
IVLAEYDLADQTYYLNKKAAELAKSVAAEFSTPDKPRFVAGSIGPTTKLPTLGHIDFDTLKTCFAEQAEALLDGGVDLLL
VETCQDVLQIKAALNGIEEVFGKRGERIPLMVSVTMESMGTMLVGSEINAVLTILEPFPIDILGLNCATGPDLMKPHIKY
LAEHSPFVVSCIPNAGLPENVGGQAHYRLTPMELRMALMHFVEDLGVQVIGGCCGTRPEHIQQLAEIAKDLKPKVRQPSL
EPAAASIYSTQPYEQDNSFLIVGERLNASGSKKCRDLLNAEDWDGLVSMARSQVKEGAHILDVNVDYVGRDGVRDMHELV
SRIVNNVTLPLMLDSTEWEKMEAGLKVAGGKCLLNSTNYEDGEPRFLKVLELAKKYGAGVVIGTIDEEGMARTAEKKFQI
AQRAYRQSVEYGIPPTEIFFDTLALPISTGIEEDRENGKATIESISRIRKELPGCHVILGVSNISFGLNSASRMVLNSVF
LHEAMTAGMDAAIVSASKILPLSKIEERHQEVCRQLIYDQRKFEGDICIYDPLTELTKLFEGVTTKRNKGVDESLPIEER
LKRHIIDGERIGLEAQLTKALEQYPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPFMEKSESGN
NAKGKVIIATVKGDVHDIGKNLVDIILSNNGYKVINLGIKQPVENIIEAYNQHKADCIAMSGLLVKSTAFMKENLEVFNE
KGINVPVILGGAALTPKFVHKDCQNTYKGKVIYGKDAFSDLHFMDKLMPAKATGKWDNSLGFLDEVETEETEPTNHKSPI
PSPQSPVPSPQSPVPIDTRRSEAVAIDIPRPTPPFWGTQLLQPSDISLEEIFWHMDLQALIAGQWQFRKPKEQSKEEYQA
FLNEKVYPVLETWKQRIIAENLLHPQVIYGYFPCQSEGNTLYVYETNSPNATEITQFEFPRQKSSKRLCIADFFAPKDSG
IIDVFPMQAVTVGEIATEFAQKLFANNQYTDYLYFHGLAVQVAEALAEWTHARIRRELGFGAEEPDNIRDILAQRYQGSR
YSFGYPACPNIQDQFKQLDLLETSRINLYMDESEQLYPEQSTTAIITYHPVAKYFTA

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1244, Percent_Identity=31.9131832797428, Blast_Score=547, Evalue=1e-155,
Organism=Escherichia coli, GI1790450, Length=1203, Percent_Identity=31.6708229426434, Blast_Score=576, Evalue=1e-165,
Organism=Escherichia coli, GI1786456, Length=313, Percent_Identity=26.1980830670927, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17535405, Length=1234, Percent_Identity=32.4149108589951, Blast_Score=565, Evalue=1e-161,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 130958; Mature: 130827

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPFLKRLHSPELPVIVFDGAMGTNLQTQNLTAEDFGGVQYEGCNEYLVHTKPEAVAKV
CCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCCEEECCCCCCEEECCHHHHHHH
HRDFLAVGADVIETDTFGATSIVLAEYDLADQTYYLNKKAAELAKSVAAEFSTPDKPRFV
HHHHHHHCCHHHCCCCCCCEEEEEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCEE
AGSIGPTTKLPTLGHIDFDTLKTCFAEQAEALLDGGVDLLLVETCQDVLQIKAALNGIEE
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
VFGKRGERIPLMVSVTMESMGTMLVGSEINAVLTILEPFPIDILGLNCATGPDLMKPHIK
HHCCCCCCCEEEEEEEHHHHCCEEECCCHHHHEEEECCCCEEEEECCCCCCCHHHHHHHH
YLAEHSPFVVSCIPNAGLPENVGGQAHYRLTPMELRMALMHFVEDLGVQVIGGCCGTRPE
HHHCCCCEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCHHEEHHHCCCCHH
HIQQLAEIAKDLKPKVRQPSLEPAAASIYSTQPYEQDNSFLIVGERLNASGSKKCRDLLN
HHHHHHHHHHHCCCHHCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHCC
AEDWDGLVSMARSQVKEGAHILDVNVDYVGRDGVRDMHELVSRIVNNVTLPLMLDSTEWE
CCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHH
KMEAGLKVAGGKCLLNSTNYEDGEPRFLKVLELAKKYGAGVVIGTIDEEGMARTAEKKFQ
HHHCCCEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHH
IAQRAYRQSVEYGIPPTEIFFDTLALPISTGIEEDRENGKATIESISRIRKELPGCHVIL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCCCEEEE
GVSNISFGLNSASRMVLNSVFLHEAMTAGMDAAIVSASKILPLSKIEERHQEVCRQLIYD
EECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
QRKFEGDICIYDPLTELTKLFEGVTTKRNKGVDESLPIEERLKRHIIDGERIGLEAQLTK
HHHCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCHHCCHHHHHHH
ALEQYPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPFMEKSESG
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
NNAKGKVIIATVKGDVHDIGKNLVDIILSNNGYKVINLGIKQPVENIIEAYNQHKADCIA
CCCCCEEEEEEECCCHHHHHHHHHHHEECCCCEEEEECCHHHHHHHHHHHHHCCCHHHHH
MSGLLVKSTAFMKENLEVFNEKGINVPVILGGAALTPKFVHKDCQNTYKGKVIYGKDAFS
HCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCHHH
DLHFMDKLMPAKATGKWDNSLGFLDEVETEETEPTNHKSPIPSPQSPVPSPQSPVPIDTR
HHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RSEAVAIDIPRPTPPFWGTQLLQPSDISLEEIFWHMDLQALIAGQWQFRKPKEQSKEEYQ
CCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
AFLNEKVYPVLETWKQRIIAENLLHPQVIYGYFPCQSEGNTLYVYETNSPNATEITQFEF
HHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCCCCEEEEEEC
PRQKSSKRLCIADFFAPKDSGIIDVFPMQAVTVGEIATEFAQKLFANNQYTDYLYFHGLA
CCCCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHH
VQVAEALAEWTHARIRRELGFGAEEPDNIRDILAQRYQGSRYSFGYPACPNIQDQFKQLD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LLETSRINLYMDESEQLYPEQSTTAIITYHPVAKYFTA
HHCCCCEEEEECCCCCCCCCCCCEEEEEECCHHHHHCC
>Mature Secondary Structure 
THPFLKRLHSPELPVIVFDGAMGTNLQTQNLTAEDFGGVQYEGCNEYLVHTKPEAVAKV
CCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCCEEECCCCCCEEECCHHHHHHH
HRDFLAVGADVIETDTFGATSIVLAEYDLADQTYYLNKKAAELAKSVAAEFSTPDKPRFV
HHHHHHHCCHHHCCCCCCCEEEEEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCEE
AGSIGPTTKLPTLGHIDFDTLKTCFAEQAEALLDGGVDLLLVETCQDVLQIKAALNGIEE
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
VFGKRGERIPLMVSVTMESMGTMLVGSEINAVLTILEPFPIDILGLNCATGPDLMKPHIK
HHCCCCCCCEEEEEEEHHHHCCEEECCCHHHHEEEECCCCEEEEECCCCCCCHHHHHHHH
YLAEHSPFVVSCIPNAGLPENVGGQAHYRLTPMELRMALMHFVEDLGVQVIGGCCGTRPE
HHHCCCCEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCHHEEHHHCCCCHH
HIQQLAEIAKDLKPKVRQPSLEPAAASIYSTQPYEQDNSFLIVGERLNASGSKKCRDLLN
HHHHHHHHHHHCCCHHCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHCC
AEDWDGLVSMARSQVKEGAHILDVNVDYVGRDGVRDMHELVSRIVNNVTLPLMLDSTEWE
CCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHH
KMEAGLKVAGGKCLLNSTNYEDGEPRFLKVLELAKKYGAGVVIGTIDEEGMARTAEKKFQ
HHHCCCEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHH
IAQRAYRQSVEYGIPPTEIFFDTLALPISTGIEEDRENGKATIESISRIRKELPGCHVIL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCCCEEEE
GVSNISFGLNSASRMVLNSVFLHEAMTAGMDAAIVSASKILPLSKIEERHQEVCRQLIYD
EECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
QRKFEGDICIYDPLTELTKLFEGVTTKRNKGVDESLPIEERLKRHIIDGERIGLEAQLTK
HHHCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCHHCCHHHHHHH
ALEQYPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPFMEKSESG
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
NNAKGKVIIATVKGDVHDIGKNLVDIILSNNGYKVINLGIKQPVENIIEAYNQHKADCIA
CCCCCEEEEEEECCCHHHHHHHHHHHEECCCCEEEEECCHHHHHHHHHHHHHCCCHHHHH
MSGLLVKSTAFMKENLEVFNEKGINVPVILGGAALTPKFVHKDCQNTYKGKVIYGKDAFS
HCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCHHH
DLHFMDKLMPAKATGKWDNSLGFLDEVETEETEPTNHKSPIPSPQSPVPSPQSPVPIDTR
HHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RSEAVAIDIPRPTPPFWGTQLLQPSDISLEEIFWHMDLQALIAGQWQFRKPKEQSKEEYQ
CCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
AFLNEKVYPVLETWKQRIIAENLLHPQVIYGYFPCQSEGNTLYVYETNSPNATEITQFEF
HHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCCCCEEEEEEC
PRQKSSKRLCIADFFAPKDSGIIDVFPMQAVTVGEIATEFAQKLFANNQYTDYLYFHGLA
CCCCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHH
VQVAEALAEWTHARIRRELGFGAEEPDNIRDILAQRYQGSRYSFGYPACPNIQDQFKQLD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LLETSRINLYMDESEQLYPEQSTTAIITYHPVAKYFTA
HHCCCCEEEEECCCCCCCCCCCCEEEEEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]