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The map label for this gene is lsrE

Identifier: 16767346

GI number: 16767346

Start: 4289409

End: 4290173

Strand: Direct

Name: lsrE

Synonym: STM4080

Alternate gene names: 16767346

Gene position: 4289409-4290173 (Clockwise)

Preceding gene: 39546390

Following gene: 16767349

Centisome position: 88.31

GC content: 51.63

Gene sequence:

>765_bases
ATGAACAGCCAGTTTGCCGGATTAACGCGCGAAGCATGTGTGGCATTGTTAGCGTCATATCCGCTTAGTGTGGGTATTCT
GGCAGGGCAGTGGATTGCGTTGCATCGCTATCTGCAACAGTTGGAAGCGCTAAACCAGCCGCTGTTGCATTTGGATTTGA
TGGATGGTCAATTTTGCCCGCAGTTTACCGTTGGGCCATGGGCAGTTGGGCAACTGCCGCAAACCTTTATCAAAGATGTT
CATTTGATGGTAGCGGATCAATGGACGGCGGCGCAAGCCTGCGTGAAGGCGGGCGCACACTGCATCACGCTTCAGGCTGA
AGGCGATATTCATCTGCATCATACGCTAAGCTGGCTTGGTCAGCAGACCGTGCCCGTTATTGGCGGTGAAATGCCGGTGA
TCCGGGGGATTAGTTTATGCCCGGCAACGCCTCTGGATGTCATTATCCCCATTCTGAGCGACGTTGAGGTTATTCAACTA
CTGGCAGTAAACCCTGGATACGGCAGTAAAATGCGCTCCAGTGATTTGCACGAGCGCGTGGCGCAGCTTCTCTGTCTACT
TGGTGATAAACGCGAAGGTAAAATTATCGTTATTGATGGGTCGTTAACGCAGGATCAGTTGCCTTCGCTGATTGCACAGG
GCATCGATCGTGTTGTTTCTGGTAGTGCGTTATTTCGTGATGATCGGCTGGTTGAGAATACGCGGAGCTGGAGGGCGATG
TTTAAGGTTGCCGGGGATACTACTTTCTTACCCTCCACAGCATAA

Upstream 100 bases:

>100_bases
AACGCCACACTACAAAACTTGCGTGGAGCAGCTTGAACCGTTGATGACCGGTCCGCGGACAAAAAAAGTTTTTATGGGTT
TGATGCCTTAAGGAGCGCTC

Downstream 100 bases:

>100_bases
ATGCCGGATGGCGGCTTTACCTTATCAGGCCTACATAAGCACTCGGCTGGTAGGCCTGATAAGCGCAGCGCCATCAGACA
TTGATTGGCAATTAAGCCTG

Product: epimerase

Products: D-Xylulose 5-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MNSQFAGLTREACVALLASYPLSVGILAGQWIALHRYLQQLEALNQPLLHLDLMDGQFCPQFTVGPWAVGQLPQTFIKDV
HLMVADQWTAAQACVKAGAHCITLQAEGDIHLHHTLSWLGQQTVPVIGGEMPVIRGISLCPATPLDVIIPILSDVEVIQL
LAVNPGYGSKMRSSDLHERVAQLLCLLGDKREGKIIVIDGSLTQDQLPSLIAQGIDRVVSGSALFRDDRLVENTRSWRAM
FKVAGDTTFLPSTA

Sequences:

>Translated_254_residues
MNSQFAGLTREACVALLASYPLSVGILAGQWIALHRYLQQLEALNQPLLHLDLMDGQFCPQFTVGPWAVGQLPQTFIKDV
HLMVADQWTAAQACVKAGAHCITLQAEGDIHLHHTLSWLGQQTVPVIGGEMPVIRGISLCPATPLDVIIPILSDVEVIQL
LAVNPGYGSKMRSSDLHERVAQLLCLLGDKREGKIIVIDGSLTQDQLPSLIAQGIDRVVSGSALFRDDRLVENTRSWRAM
FKVAGDTTFLPSTA
>Mature_254_residues
MNSQFAGLTREACVALLASYPLSVGILAGQWIALHRYLQQLEALNQPLLHLDLMDGQFCPQFTVGPWAVGQLPQTFIKDV
HLMVADQWTAAQACVKAGAHCITLQAEGDIHLHHTLSWLGQQTVPVIGGEMPVIRGISLCPATPLDVIIPILSDVEVIQL
LAVNPGYGSKMRSSDLHERVAQLLCLLGDKREGKIIVIDGSLTQDQLPSLIAQGIDRVVSGSALFRDDRLVENTRSWRAM
FKVAGDTTFLPSTA

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family

Homologues:

Organism=Escherichia coli, GI1789788, Length=229, Percent_Identity=24.8908296943231, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17552948, Length=210, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LSRE_SALCH (Q57HD7)

Other databases:

- EMBL:   AE017220
- RefSeq:   YP_218956.1
- HSSP:   P74061
- ProteinModelPortal:   Q57HD7
- SMR:   Q57HD7
- PRIDE:   Q57HD7
- GeneID:   3336508
- GenomeReviews:   AE017220_GR
- KEGG:   sec:SC3969
- HOGENOM:   HBG495037
- OMA:   FDIADGQ
- ProtClustDB:   PRK14057
- BioCyc:   SENT321314:SCH_3969-MONOMER
- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR11749

Pfam domain/function: PF00834 Ribul_P_3_epim; SSF51366 RibP_bind_barrel

EC number: 5.1.3.1 [C]

Molecular weight: Translated: 27635; Mature: 27635

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12ef1d04)-;

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQFAGLTREACVALLASYPLSVGILAGQWIALHRYLQQLEALNQPLLHLDLMDGQFCP
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
QFTVGPWAVGQLPQTFIKDVHLMVADQWTAAQACVKAGAHCITLQAEGDIHLHHTLSWLG
CCCCCCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCEEHHHHHHHHC
QQTVPVIGGEMPVIRGISLCPATPLDVIIPILSDVEVIQLLAVNPGYGSKMRSSDLHERV
CCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCHHEEHEEEECCCCCCCCCHHHHHHHH
AQLLCLLGDKREGKIIVIDGSLTQDQLPSLIAQGIDRVVSGSALFRDDRLVENTRSWRAM
HHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHH
FKVAGDTTFLPSTA
HHCCCCCEECCCCH
>Mature Secondary Structure
MNSQFAGLTREACVALLASYPLSVGILAGQWIALHRYLQQLEALNQPLLHLDLMDGQFCP
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
QFTVGPWAVGQLPQTFIKDVHLMVADQWTAAQACVKAGAHCITLQAEGDIHLHHTLSWLG
CCCCCCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCEEHHHHHHHHC
QQTVPVIGGEMPVIRGISLCPATPLDVIIPILSDVEVIQLLAVNPGYGSKMRSSDLHERV
CCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCHHEEHEEEECCCCCCCCCHHHHHHHH
AQLLCLLGDKREGKIIVIDGSLTQDQLPSLIAQGIDRVVSGSALFRDDRLVENTRSWRAM
HHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHH
FKVAGDTTFLPSTA
HHCCCCCEECCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): 78000 [C]

Specific activity: NA

Km value (mM): 15 {D-ribulose} 2.4 {D-ribulose-5-phosphate}} [C]

Substrates: D-Ribulose 5-phosphate [C]

Specific reaction: D-Ribulose 5-phosphate <==> D-Xylulose 5-phosphate [C]

General reaction: Epimerization [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA