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The map label for this gene is yidY [H]

Identifier: 16767131

GI number: 16767131

Start: 4054077

End: 4055264

Strand: Direct

Name: yidY [H]

Synonym: STM3847

Alternate gene names: 16767131

Gene position: 4054077-4055264 (Clockwise)

Preceding gene: 39546377

Following gene: 16767132

Centisome position: 83.46

GC content: 55.47

Gene sequence:

>1188_bases
ATGAAACGTTTTCTACTGTGTAGTTTTGCCCTGGTTTTACTCTATCCTGCCGGTATTGATATGTATCTGGTCGGTTTACC
GCGTATAGCCGCCGATCTGAACGCCAGCGAGGCGCAGTTGCATATCGCCTTCTCCGTTTACCTGGCCGGAATGGCGACGG
CCATGCTGTTTGCCGGGAAGATAGCCGACCAGTCAGGCCGCAAGCCGGTCGCGATCGTCGGCGCGCTCGTCTTTATGATG
GCCTCACTGCTTTGTTCACGGGCGTCGGAAGGCTCGCTATTTCTGAGTGGGCGTTTTCTTCAGGGAGTAGGCGCAGGCGG
CTGCTATGTGGTGGCGTTCGCCATTCTGCGCGACACGCTCGACGAGCATCGCCGGGCGAAAGTGCTGTCATTATTGAATG
GGATTACCTGTATTGTGCCGGTACTCGCCCCGGTGGTGGGGCATTTGATTATGCTTCGTTTCCCCTGGCAAAGTCTGTTC
TATACGATGTCCGCGATGGGCATTATTGTGGGCCTGTTATCACTGTTTATCCTGCGCGAGACGCGCCCGGTAAGGCTGGC
TCCACGCGATTTATCACGATCGTCGCCCGCCGCCGAGTCGCTGATTAACCGTTTTTTCGTTAGTCGACTGGCGATCACCA
CCCTTAGCGTGTCGGTGATCCTGACCTTTGTCAATGCCTCTCCAGTGCTGCTGATGGAGGTGATGGGATTTAGCCGTGGC
GACTATGCCATTACCATGGCGCTCACCGCAGGCGTCAGTATGGTCGTCTCTTTTTCCACCCCTTTTGCGCTTGGGTTATT
TAAGCCGCGAACCTTAATGCTCGTCTCACAGGGGCTGTTTTTGACGGCTGGCGTGACGTTAAGCCTTGCTCATACCAATA
CCGTCACACTCTTTGGCCTGACGCTTATCTGCGCCGGATTCTCGGTTGGTTTTGGCGTCGCGATGAGCCAGGCGCTGGGG
CCGTTTTCGCTGCGCGCCGGAGTGGCCAGTTCCACGCTCGGTATCGCGCAGGTTTGCGGTTCATCACTGTGGATTTGGCT
GGCGGCAATACTCGGTATCAGCGCGATGAATATGCTGATCGGGATTCTGATTGGTTGTAGCATAGTGAGTATTCTGCTGA
TCTTCTCCGTCACGCCCAACAGGTCCGTAGCCGAGCATGAAGAAATCCCTTACCAATCTCGACCTTAA

Upstream 100 bases:

>100_bases
TATCTCATTGCCTCATAGGAAATCACTGTTGTCCAAATGGCAACTCGTCTCGCGCAACATCGCCCCGTATTCTTAGCGCC
ACACTTTTCGTGAGGCCGCT

Downstream 100 bases:

>100_bases
TTTGCTGTTATGCCTACAGTTACTCATGCAGGAGCGCAGCGTCACTAAAGCTGCAAAACGGATGAACGTAACGCCCTCAG
CGGTCAGCAAATCGCTGGCG

Product: multidrug efflux system protein MdtL

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMATAMLFAGKIADQSGRKPVAIVGALVFMM
ASLLCSRASEGSLFLSGRFLQGVGAGGCYVVAFAILRDTLDEHRRAKVLSLLNGITCIVPVLAPVVGHLIMLRFPWQSLF
YTMSAMGIIVGLLSLFILRETRPVRLAPRDLSRSSPAAESLINRFFVSRLAITTLSVSVILTFVNASPVLLMEVMGFSRG
DYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVSQGLFLTAGVTLSLAHTNTVTLFGLTLICAGFSVGFGVAMSQALG
PFSLRAGVASSTLGIAQVCGSSLWIWLAAILGISAMNMLIGILIGCSIVSILLIFSVTPNRSVAEHEEIPYQSRP

Sequences:

>Translated_395_residues
MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMATAMLFAGKIADQSGRKPVAIVGALVFMM
ASLLCSRASEGSLFLSGRFLQGVGAGGCYVVAFAILRDTLDEHRRAKVLSLLNGITCIVPVLAPVVGHLIMLRFPWQSLF
YTMSAMGIIVGLLSLFILRETRPVRLAPRDLSRSSPAAESLINRFFVSRLAITTLSVSVILTFVNASPVLLMEVMGFSRG
DYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVSQGLFLTAGVTLSLAHTNTVTLFGLTLICAGFSVGFGVAMSQALG
PFSLRAGVASSTLGIAQVCGSSLWIWLAAILGISAMNMLIGILIGCSIVSILLIFSVTPNRSVAEHEEIPYQSRP
>Mature_395_residues
MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMATAMLFAGKIADQSGRKPVAIVGALVFMM
ASLLCSRASEGSLFLSGRFLQGVGAGGCYVVAFAILRDTLDEHRRAKVLSLLNGITCIVPVLAPVVGHLIMLRFPWQSLF
YTMSAMGIIVGLLSLFILRETRPVRLAPRDLSRSSPAAESLINRFFVSRLAITTLSVSVILTFVNASPVLLMEVMGFSRG
DYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVSQGLFLTAGVTLSLAHTNTVTLFGLTLICAGFSVGFGVAMSQALG
PFSLRAGVASSTLGIAQVCGSSLWIWLAAILGISAMNMLIGILIGCSIVSILLIFSVTPNRSVAEHEEIPYQSRP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790146, Length=393, Percent_Identity=77.8625954198473, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1788509, Length=241, Percent_Identity=27.8008298755187, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994889, Length=237, Percent_Identity=28.2700421940928, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790794, Length=243, Percent_Identity=26.7489711934156, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082312, Length=345, Percent_Identity=28.4057971014493, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787065, Length=237, Percent_Identity=25.7383966244726, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42028; Mature: 42028

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMATAMLFAGK
CCHHHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCCHHHEEHHHHHHHHHHHHHHHHHHH
IADQSGRKPVAIVGALVFMMASLLCSRASEGSLFLSGRFLQGVGAGGCYVVAFAILRDTL
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHCCCCCHHHHHHHHHHHHHH
DEHRRAKVLSLLNGITCIVPVLAPVVGHLIMLRFPWQSLFYTMSAMGIIVGLLSLFILRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
TRPVRLAPRDLSRSSPAAESLINRFFVSRLAITTLSVSVILTFVNASPVLLMEVMGFSRG
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
DYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVSQGLFLTAGVTLSLAHTNTVTLFGL
CEEEEEEHHHCHHHEEEECCCCEECCCCCCEEEHHHCCCEEEECCEEEEECCCHHHHHHH
TLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAILGISAMNMLI
HHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GILIGCSIVSILLIFSVTPNRSVAEHEEIPYQSRP
HHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMATAMLFAGK
CCHHHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCCHHHEEHHHHHHHHHHHHHHHHHHH
IADQSGRKPVAIVGALVFMMASLLCSRASEGSLFLSGRFLQGVGAGGCYVVAFAILRDTL
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHCCCCCHHHHHHHHHHHHHH
DEHRRAKVLSLLNGITCIVPVLAPVVGHLIMLRFPWQSLFYTMSAMGIIVGLLSLFILRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
TRPVRLAPRDLSRSSPAAESLINRFFVSRLAITTLSVSVILTFVNASPVLLMEVMGFSRG
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
DYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVSQGLFLTAGVTLSLAHTNTVTLFGL
CEEEEEEHHHCHHHEEEECCCCEECCCCCCEEEHHHCCCEEEECCEEEEECCCHHHHHHH
TLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAILGISAMNMLI
HHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GILIGCSIVSILLIFSVTPNRSVAEHEEIPYQSRP
HHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA