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The map label for this gene is codA [H]

Identifier: 16766629

GI number: 16766629

Start: 3503078

End: 3504358

Strand: Direct

Name: codA [H]

Synonym: STM3334

Alternate gene names: 16766629

Gene position: 3503078-3504358 (Clockwise)

Preceding gene: 16766628

Following gene: 16766642

Centisome position: 72.12

GC content: 55.5

Gene sequence:

>1281_bases
ATGCAGAACAATAACATCACCATTCGTCAGACGCGTCTGCAGGGACACGAAGGATTATGGCAGATTACGATTGAAAACGG
GCGCTTTAGCCGGATTGAGCCTCAGGAAGCCGCATCGTTACCGCAGGGCGAAGTGCTTGATGCCGAAGGCGGTCTGGCTA
TTCCACCGTTTGTTGAGCCACATATCCACCTGGATACCACGCAAACGGCGGGTGAACCGAGCTGGAACCAGTCCGGCACA
CTGTTTGAAGGGATTGAGCGCTGGGCAGAACGTAAAGCAATGCTCACGCATGAAGATGTGAAAGCGCGCGCGATGCAGAC
CCTGAAATGGCAGATGGCTAACGGCATCCAGTACGTTCGTACTCACGTTGACGTTTCAGATCCTACGCTCACCGCGCTGA
AAGCCATGCTGGAAGTGAAGCAAGAGGTTGCGCCGTGGGTAGACCTACAAATCGTCGCCTTTCCGCAAGAAGGTGTTCTG
TCTTATCCCAACGGTGAAGCGCTGTTAGAGGAAGCCGTGCGTTTGGGCGCTGACGTTATTGGCGCCATTCCGCACTTTGA
GTTCACGCGGGAATATGGCGTTGAATCGCTGCACAAAATCTTTGCACTGGCGCAGAAATACGATCGCTTGATCGATGTGC
ACTGCGACGAAATTGATGACGAGCAGTCTCGCTTTGTCGAAACGGTCGCGGCGCTGGCGCATCGTGATAGCATGGGGGCG
CGCGTGACCGCCAGCCACACCACGGCTATGCACTCGTACAACGGCGCGTATGCGTCACGCCTGTTCCGCCTGTTGAAAAT
GTCGGGGATTAACTTCGTCGCCAACCCGCTGGTGAATATTCATCTGCAAGGGCGGTTTGACACTTACCCGAAACGTCGTG
GCGTCACGCGGGTGAAAGAGATGCTGGAAGCGGGGATCAATGTCTGCTTTGGCCATGATGACGTCTTCGACCCGTGGTAT
CCATTAGGCACCGCCAATATGCTGCAGGTGCTGCATATGGGGTTACACGTTTGCCAGTTGATGGGGTATGGGCAAATCAA
CGACGGGTTAAATCTGATCACTATCCACAGCGCAAAAACTTTGCACCTGCAGGACTACGGTCTGAGCGTCGGCAATGCCG
CGAATCTGGTTATCTTACCCGCTGAGAATGGATTCGACGCGGTACGTCGCCAGACGCCTGCCCGTTACTCGATTCGCCAC
GGGCGGGTAATTGCCGAGACGGTGCCGAGCCAGACGACGCTGCACCTGACCCAGCCGGAAGCCGTGACGTTTAAGCGTTA
A

Upstream 100 bases:

>100_bases
GGTATTGTGCCCGTCAACGCCGTACTCGGCGGCGTCTTCAGCTATATCCTGCTGAATCCACTTTTCAACCGCAGCCTTGC
TAAATCACCAGAGGTCAGCC

Downstream 100 bases:

>100_bases
CCCGTCATACCCGCGCTCTCCGGCACATTCACCACGCAGCCCCGTAAGGGGCTGCGTTCGGAAGACTGCTCCGGCAAGAG
ATTCAGGCCGCCAGCAGACT

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MQNNNITIRQTRLQGHEGLWQITIENGRFSRIEPQEAASLPQGEVLDAEGGLAIPPFVEPHIHLDTTQTAGEPSWNQSGT
LFEGIERWAERKAMLTHEDVKARAMQTLKWQMANGIQYVRTHVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGVL
SYPNGEALLEEAVRLGADVIGAIPHFEFTREYGVESLHKIFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHRDSMGA
RVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGVTRVKEMLEAGINVCFGHDDVFDPWY
PLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITIHSAKTLHLQDYGLSVGNAANLVILPAENGFDAVRRQTPARYSIRH
GRVIAETVPSQTTLHLTQPEAVTFKR

Sequences:

>Translated_426_residues
MQNNNITIRQTRLQGHEGLWQITIENGRFSRIEPQEAASLPQGEVLDAEGGLAIPPFVEPHIHLDTTQTAGEPSWNQSGT
LFEGIERWAERKAMLTHEDVKARAMQTLKWQMANGIQYVRTHVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGVL
SYPNGEALLEEAVRLGADVIGAIPHFEFTREYGVESLHKIFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHRDSMGA
RVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGVTRVKEMLEAGINVCFGHDDVFDPWY
PLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITIHSAKTLHLQDYGLSVGNAANLVILPAENGFDAVRRQTPARYSIRH
GRVIAETVPSQTTLHLTQPEAVTFKR
>Mature_426_residues
MQNNNITIRQTRLQGHEGLWQITIENGRFSRIEPQEAASLPQGEVLDAEGGLAIPPFVEPHIHLDTTQTAGEPSWNQSGT
LFEGIERWAERKAMLTHEDVKARAMQTLKWQMANGIQYVRTHVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGVL
SYPNGEALLEEAVRLGADVIGAIPHFEFTREYGVESLHKIFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHRDSMGA
RVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGVTRVKEMLEAGINVCFGHDDVFDPWY
PLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITIHSAKTLHLQDYGLSVGNAANLVILPAENGFDAVRRQTPARYSIRH
GRVIAETVPSQTTLHLTQPEAVTFKR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=427, Percent_Identity=82.903981264637, Blast_Score=748, Evalue=0.0,
Organism=Escherichia coli, GI1786517, Length=394, Percent_Identity=24.6192893401015, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 47627; Mature: 47627

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNNNITIRQTRLQGHEGLWQITIENGRFSRIEPQEAASLPQGEVLDAEGGLAIPPFVEP
CCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHCCCCCCEEECCCCEECCCCCCC
HIHLDTTQTAGEPSWNQSGTLFEGIERWAERKAMLTHEDVKARAMQTLKWQMANGIQYVR
CEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEHH
THVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGVLSYPNGEALLEEAVRLGADVI
EECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHH
GAIPHFEFTREYGVESLHKIFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHRDSMGA
HCCCCHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
RVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGVTRVKE
EEEECHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCCHHHHHH
MLEAGINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITIHSAKT
HHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEE
LHLQDYGLSVGNAANLVILPAENGFDAVRRQTPARYSIRHGRVIAETVPSQTTLHLTQPE
EEEEECCCCCCCCCCEEEEECCCCHHHHHHCCCCCEECCCCEEEEECCCCCEEEEEECCC
AVTFKR
CCCCCC
>Mature Secondary Structure
MQNNNITIRQTRLQGHEGLWQITIENGRFSRIEPQEAASLPQGEVLDAEGGLAIPPFVEP
CCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHCCCCCCEEECCCCEECCCCCCC
HIHLDTTQTAGEPSWNQSGTLFEGIERWAERKAMLTHEDVKARAMQTLKWQMANGIQYVR
CEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEHH
THVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGVLSYPNGEALLEEAVRLGADVI
EECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHH
GAIPHFEFTREYGVESLHKIFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHRDSMGA
HCCCCHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
RVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGVTRVKE
EEEECHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCCHHHHHH
MLEAGINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITIHSAKT
HHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEE
LHLQDYGLSVGNAANLVILPAENGFDAVRRQTPARYSIRHGRVIAETVPSQTTLHLTQPE
EEEEECCCCCCCCCCEEEEECCCCHHHHHHCCCCCEECCCCEEEEECCCCCEEEEEECCC
AVTFKR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]