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The map label for this gene is codB [H]

Identifier: 16766628

GI number: 16766628

Start: 3501838

End: 3503091

Strand: Direct

Name: codB [H]

Synonym: STM3333

Alternate gene names: 16766628

Gene position: 3501838-3503091 (Clockwise)

Preceding gene: 16766627

Following gene: 16766629

Centisome position: 72.09

GC content: 55.5

Gene sequence:

>1254_bases
GTGTCGCAGGACAACAATTATAGCCAGGGCCCCGTCCCTCTGGCTGCGCGGAAGGGCGTGATTCCACTGACGTTTGTCAT
GTTGGGTTTAACGTTTTTTTCCGCCAGTATGTGGACCGGAGGGACACTCGGCACCGGTCTTTCTTATAATGATTTCTTCC
TCGCAGTTCTCTTCGGTAATCTCCTCCTCGGTATCTACACTGCATTTCTTGGTTACATCGGCGCAAAAACCGGACTCTCC
ACCCACCTCCTTGCACGTTACTCCTTTGGCGTTAAAGGCTCATGGCTTCCCTCGCTACTGCTAGGCGGTACTCAAGTGGG
CTGGTTTGGCGTTGGCGTAGCGATGTTCGCTATTCCGGTCAGTAAAGCGACGGGCATTGATGCCAATATTCTGATTGCCG
TTTCGGGTCTACTGATGACCCTGACCATTTTTTTCGGCATCTCGGCGCTGACCATTTTGTCTATCGTTGCCGTACCCGCG
ATCGTTATTCTGGGCAGCTACTCCGTCTGGCTGGCGGTCAGCGGCGTGGGTGGGCTGGAGCATTTAAAAACGATAGTGCC
GCAGACGCCGCTGGATTTTTCCAGCGCGCTGGCGCTGGTGGTGGGCTCGTTTGTCAGCGCCGGTACATTGACCGCCGACT
TCGTCCGCTTCGGGCGTCATGCCAAAAGCGCCGTACTGATTGCGATGGTCGCTTTTTTCCTCGGCAACTCGCTGATGTTT
ATCTTTGGCGCGGCAGGCGCTGCCGCCGTCGGTCAGGCGGATATCTCTGACGTGATGATAGCGCAGGGGCTGCTGCTGCC
CGCGATTGTGGTGCTTGGCCTGAATATCTGGACCACCAACGATAACGCGCTGTACGCATCGGGTCTGGGCTTCGCCAATA
TTACCGGTCTTTCCAGCCGTACGCTGTCGGTGGTGAACGGGATTATCGGTACCGTGTGCGCGCTGTGGCTTTACAATAAT
TTTGTCGGCTGGCTGACGTTCCTGTCATCTGCCATCCCACCGATTGGCGGAGTGATTATTGCCGACTATCTGTTGAACCG
CCGCCGCTATGCCGACTTCAACACCGTGCGCTTTATTCCCGTTAACTGGATTGCTATTCTTTCCGTCGCGCTGGGCATCG
CCGCCGGACATTATGTTCCGGGTATTGTGCCCGTCAACGCCGTACTCGGCGGCGTCTTCAGCTATATCCTGCTGAATCCA
CTTTTCAACCGCAGCCTTGCTAAATCACCAGAGGTCAGCCATGCAGAACAATAA

Upstream 100 bases:

>100_bases
TGAATAATTATCAAAAAAAATATCACACGAAAACGTTTGCTTTATTCTGGAAACTGTATATTATGCGGCGGATTTTTTGG
GCAAAATTCATGGAGGCGTT

Downstream 100 bases:

>100_bases
CATCACCATTCGTCAGACGCGTCTGCAGGGACACGAAGGATTATGGCAGATTACGATTGAAAACGGGCGCTTTAGCCGGA
TTGAGCCTCAGGAAGCCGCA

Product: cytosine permease

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSQDNNYSQGPVPLAARKGVIPLTFVMLGLTFFSASMWTGGTLGTGLSYNDFFLAVLFGNLLLGIYTAFLGYIGAKTGLS
THLLARYSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPVSKATGIDANILIAVSGLLMTLTIFFGISALTILSIVAVPA
IVILGSYSVWLAVSGVGGLEHLKTIVPQTPLDFSSALALVVGSFVSAGTLTADFVRFGRHAKSAVLIAMVAFFLGNSLMF
IFGAAGAAAVGQADISDVMIAQGLLLPAIVVLGLNIWTTNDNALYASGLGFANITGLSSRTLSVVNGIIGTVCALWLYNN
FVGWLTFLSSAIPPIGGVIIADYLLNRRRYADFNTVRFIPVNWIAILSVALGIAAGHYVPGIVPVNAVLGGVFSYILLNP
LFNRSLAKSPEVSHAEQ

Sequences:

>Translated_417_residues
MSQDNNYSQGPVPLAARKGVIPLTFVMLGLTFFSASMWTGGTLGTGLSYNDFFLAVLFGNLLLGIYTAFLGYIGAKTGLS
THLLARYSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPVSKATGIDANILIAVSGLLMTLTIFFGISALTILSIVAVPA
IVILGSYSVWLAVSGVGGLEHLKTIVPQTPLDFSSALALVVGSFVSAGTLTADFVRFGRHAKSAVLIAMVAFFLGNSLMF
IFGAAGAAAVGQADISDVMIAQGLLLPAIVVLGLNIWTTNDNALYASGLGFANITGLSSRTLSVVNGIIGTVCALWLYNN
FVGWLTFLSSAIPPIGGVIIADYLLNRRRYADFNTVRFIPVNWIAILSVALGIAAGHYVPGIVPVNAVLGGVFSYILLNP
LFNRSLAKSPEVSHAEQ
>Mature_416_residues
SQDNNYSQGPVPLAARKGVIPLTFVMLGLTFFSASMWTGGTLGTGLSYNDFFLAVLFGNLLLGIYTAFLGYIGAKTGLST
HLLARYSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPVSKATGIDANILIAVSGLLMTLTIFFGISALTILSIVAVPAI
VILGSYSVWLAVSGVGGLEHLKTIVPQTPLDFSSALALVVGSFVSAGTLTADFVRFGRHAKSAVLIAMVAFFLGNSLMFI
FGAAGAAAVGQADISDVMIAQGLLLPAIVVLGLNIWTTNDNALYASGLGFANITGLSSRTLSVVNGIIGTVCALWLYNNF
VGWLTFLSSAIPPIGGVIIADYLLNRRRYADFNTVRFIPVNWIAILSVALGIAAGHYVPGIVPVNAVLGGVFSYILLNPL
FNRSLAKSPEVSHAEQ

Specific function: Required for cytosine transport into the cell [H]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI1786530, Length=416, Percent_Identity=82.9326923076923, Blast_Score=669, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 43652; Mature: 43521

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDNNYSQGPVPLAARKGVIPLTFVMLGLTFFSASMWTGGTLGTGLSYNDFFLAVLFGN
CCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LLLGIYTAFLGYIGAKTGLSTHLLARYSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPV
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHC
SKATGIDANILIAVSGLLMTLTIFFGISALTILSIVAVPAIVILGSYSVWLAVSGVGGLE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
HLKTIVPQTPLDFSSALALVVGSFVSAGTLTADFVRFGRHAKSAVLIAMVAFFLGNSLMF
HHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IFGAAGAAAVGQADISDVMIAQGLLLPAIVVLGLNIWTTNDNALYASGLGFANITGLSSR
EEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCHHCCCCCHH
TLSVVNGIIGTVCALWLYNNFVGWLTFLSSAIPPIGGVIIADYLLNRRRYADFNTVRFIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHCCCCCCEEEEH
VNWIAILSVALGIAAGHYVPGIVPVNAVLGGVFSYILLNPLFNRSLAKSPEVSHAEQ
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SQDNNYSQGPVPLAARKGVIPLTFVMLGLTFFSASMWTGGTLGTGLSYNDFFLAVLFGN
CCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LLLGIYTAFLGYIGAKTGLSTHLLARYSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPV
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHC
SKATGIDANILIAVSGLLMTLTIFFGISALTILSIVAVPAIVILGSYSVWLAVSGVGGLE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
HLKTIVPQTPLDFSSALALVVGSFVSAGTLTADFVRFGRHAKSAVLIAMVAFFLGNSLMF
HHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IFGAAGAAAVGQADISDVMIAQGLLLPAIVVLGLNIWTTNDNALYASGLGFANITGLSSR
EEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCHHCCCCCHH
TLSVVNGIIGTVCALWLYNNFVGWLTFLSSAIPPIGGVIIADYLLNRRRYADFNTVRFIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHCCCCCCEEEEH
VNWIAILSVALGIAAGHYVPGIVPVNAVLGGVFSYILLNPLFNRSLAKSPEVSHAEQ
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]