Click here to switch to the map view.

The map label for this gene is intA [H]

Identifier: 16766052

GI number: 16766052

Start: 2878169

End: 2879233

Strand: Direct

Name: intA [H]

Synonym: STM2740

Alternate gene names: 16766052

Gene position: 2878169-2879233 (Clockwise)

Preceding gene: 16766051

Following gene: 39546348

Centisome position: 59.25

GC content: 56.53

Gene sequence:

>1065_bases
ATGCCTAACCAACTGAAACCCTTAACAAATGTGGAGATCGCTGGCGCGAAGCCCCGTAGCACAGACTATGAGCTACGGGA
CGGTGAAGGCCTGTACTTGCTGGTTAAGACTTCAGGGAGGAAGGCCTGGCATTTCGAGTATTATCATCCCGTCACCAAAA
AGCGCACCAAAACCAGCCTTGGCCCTTACCCGGTCGTTACACTGGCCATGGCTCGCGAAACTCGCACGAAATACAGACGA
CTGCTCTATCAGGGCATCGATCCCCGTCAACACTTAGCAGGAATAGCTGAAGAAAAACGCATCCAGAATGAATGCACGCT
GGAAAAAGTTGCGGAACAGTGGCTCAAAGAGAAGAAACGGACCAGCGATCTTAGCGAAGATCACGCCAAAGATGTCTGGC
GCTCGCTGGAGATGCACGTCTTCCCCTCTCTGGGTAACACACCCGTTACCGAGATCCGCCCGAAGATGCTCAAGGAACAC
CTCACCCCGCTGGAAGAACAGGGCATCCTCGAAACGCTGCGGCGAGTCATCTCACGGCTTAATGAAATCTTCCGTTTTGC
CATCTCCGAAGAGCTCATCGAATTCAATCCGGCTGACAACCTGGTCGCCCGCTTCAAGAAACCAAAAAAGCAGAACATGC
CCGCCCTTCACCCCAGTGAACTGGGCAGGCTAATGCTGGCGCTACAGAACGCTTCTATCCGCAAGGAAACCCGCTGCCTT
ATCGAATGGGAGCTACTGACCTGGGTTCGCCCCGGCGAGGCCGTCAGCGCCCGCTGGTGCGACATCGACATGAAAAAAGC
AGAATGGCGCATCCCCGATACCTTTATGAAGATGAACCGTTCGCACACGGTGCCGCTTAGCAAACAGGCGCTGCGCGTTC
TTCAGATCATGGAGCCCGTCAGCCGCCATCGTCCGTGGGTCTTCCCCAGCATCCGCAAACCACTGGAGCATATGCACCAG
CAGACCGCGAACGCCGCGCTTATCCGCATGGGGTTCGGCGGCGAACTGGTCGCCCACGGCATGCGCAGCCGCCAGGACCG
CAGGCGCAGGTCATTTTCCCCGTGA

Upstream 100 bases:

>100_bases
TTGTTGCATGTGTGGTCATGATCTCTGTATGAATCTTGAGCTTTTGGCACCATGTTTAGCACCACGGTATCGTGGGGCTA
AAAAAGCGTGGTGCTAAAAC

Downstream 100 bases:

>100_bases
AGTCCTGGAATCTGTGCTGGCACACCAGAAAGAAGACGAGATCGAAGCGGCCTACAACCGCAGCGACTATCTGGAACAAA
GGCGACCGCTGATGCAGTGG

Product: integrase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MPNQLKPLTNVEIAGAKPRSTDYELRDGEGLYLLVKTSGRKAWHFEYYHPVTKKRTKTSLGPYPVVTLAMARETRTKYRR
LLYQGIDPRQHLAGIAEEKRIQNECTLEKVAEQWLKEKKRTSDLSEDHAKDVWRSLEMHVFPSLGNTPVTEIRPKMLKEH
LTPLEEQGILETLRRVISRLNEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLALQNASIRKETRCL
IEWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPVSRHRPWVFPSIRKPLEHMHQ
QTANAALIRMGFGGELVAHGMRSRQDRRRRSFSP

Sequences:

>Translated_354_residues
MPNQLKPLTNVEIAGAKPRSTDYELRDGEGLYLLVKTSGRKAWHFEYYHPVTKKRTKTSLGPYPVVTLAMARETRTKYRR
LLYQGIDPRQHLAGIAEEKRIQNECTLEKVAEQWLKEKKRTSDLSEDHAKDVWRSLEMHVFPSLGNTPVTEIRPKMLKEH
LTPLEEQGILETLRRVISRLNEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLALQNASIRKETRCL
IEWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPVSRHRPWVFPSIRKPLEHMHQ
QTANAALIRMGFGGELVAHGMRSRQDRRRRSFSP
>Mature_353_residues
PNQLKPLTNVEIAGAKPRSTDYELRDGEGLYLLVKTSGRKAWHFEYYHPVTKKRTKTSLGPYPVVTLAMARETRTKYRRL
LYQGIDPRQHLAGIAEEKRIQNECTLEKVAEQWLKEKKRTSDLSEDHAKDVWRSLEMHVFPSLGNTPVTEIRPKMLKEHL
TPLEEQGILETLRRVISRLNEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLALQNASIRKETRCLI
EWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPVSRHRPWVFPSIRKPLEHMHQQ
TANAALIRMGFGGELVAHGMRSRQDRRRRSFSP

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=343, Percent_Identity=46.9387755102041, Blast_Score=331, Evalue=4e-92,
Organism=Escherichia coli, GI145693166, Length=347, Percent_Identity=32.5648414985591, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1788690, Length=341, Percent_Identity=28.1524926686217, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 41337; Mature: 41205

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNQLKPLTNVEIAGAKPRSTDYELRDGEGLYLLVKTSGRKAWHFEYYHPVTKKRTKTSL
CCCCCCCCCCEEECCCCCCCCCCEEECCCCEEEEEEECCCCEEEEEHHCCHHHHHHHCCC
GPYPVVTLAMARETRTKYRRLLYQGIDPRQHLAGIAEEKRIQNECTLEKVAEQWLKEKKR
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSDLSEDHAKDVWRSLEMHVFPSLGNTPVTEIRPKMLKEHLTPLEEQGILETLRRVISRL
HCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
NEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLALQNASIRKETRCL
HHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
IEWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPV
EEEHHHHHCCCCCHHCCEECCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SRHRPWVFPSIRKPLEHMHQQTANAALIRMGFGGELVAHGMRSRQDRRRRSFSP
HHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PNQLKPLTNVEIAGAKPRSTDYELRDGEGLYLLVKTSGRKAWHFEYYHPVTKKRTKTSL
CCCCCCCCCEEECCCCCCCCCCEEECCCCEEEEEEECCCCEEEEEHHCCHHHHHHHCCC
GPYPVVTLAMARETRTKYRRLLYQGIDPRQHLAGIAEEKRIQNECTLEKVAEQWLKEKKR
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSDLSEDHAKDVWRSLEMHVFPSLGNTPVTEIRPKMLKEHLTPLEEQGILETLRRVISRL
HCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
NEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLALQNASIRKETRCL
HHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
IEWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPV
EEEHHHHHCCCCCHHCCEECCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SRHRPWVFPSIRKPLEHMHQQTANAALIRMGFGGELVAHGMRSRQDRRRRSFSP
HHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]