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The map label for this gene is cbiC [H]

Identifier: 15922136

GI number: 15922136

Start: 1836234

End: 1837235

Strand: Reverse

Name: cbiC [H]

Synonym: ST1824

Alternate gene names: 15922136

Gene position: 1837235-1836234 (Counterclockwise)

Preceding gene: 15922137

Following gene: 15922135

Centisome position: 68.18

GC content: 35.03

Gene sequence:

>1002_bases
GTGAGCAATTCAGCTATTATAATAATCACACATGGTTCTAGAAGAAATACCTTTGTAGAGGACATGGTAAATCTAGCAAG
ATATATAGAAGAAAAACTAGAAGTACCAGTTTTTTTATCACATAATGAATATACCGAACCTAATTGGAGGAATATTGTAT
CCGAATTACTTTCAAAGGGAATTAATCACATAGTCTTTGCTTTAGCTTTTTTGGGAAGGGGAAATCATGTAGCTAAAGAC
ATTATGGGAAGTTTTGGTGTTAGTGAGTTTTATAAATGGGTTAAGAGTACTTATGAGGGTAAAGAAATTAACGTCTATTT
TACAAAGCCTTTAGCGGACTCAAACCTAGTGAAATTAGCACTTTTTTACAGAGTTTCTACAGCGTTTCCTCAACAAGAAA
ATGAGTACATAGAAGACCCAGAAGAAATTGAAGAAAGAACAATGAAATTTATCAGGGAAAAAGTCAGAGAACGATTTCCA
TATATGGGTGACAGAGAGATAGAGATAATAGCCAGAGCAGTATATGCGTCTGGTAATCTTGATTTAGCAGATAAAATCTA
TATTTCGCAAGATGCAGTTGATATTGGAATAGAAAGTTTGAAAACAGGCATTTCAATTTTGACTGATGTAAAGATGGTTT
CTGCAGGAATAAGATGGAATAAAGTTGAAAATTACCTAGATAAAGCCTCAGAATTAGCTAAGGAAATGAGAATTACTAGA
ACCGCGGCCGGTATAAGACTTGGTTTATCTTCTCCAAAGATTGTAGTTATTGGAAACGCTCCAACAGCTGTTGCCGAAGT
TTTAAAAATAAGGAAAGAAGGTGTAGAGATACCTTTGGTTATTGCTACTCCACCAGGATTTACAAATGCCGTTGAGGTTA
AGGAGGATTTAATAAGATCTGGCATACCATGTATAGTGTTAAGAGGAACTTACGGTGGTAGTAGTATAGCAGTATCAATC
ATAAATGAGCTAATTAGAATGGTGAGGAGTTATGGCGGGTAA

Upstream 100 bases:

>100_bases
TAACGCGTGATCTAAAATTTAGTGATCTTACTATAGTTTATATTCCTCCTTGTTCCTTTTCTTAGAAATATTTTTATATT
TGGATAAGCTATCCAATACC

Downstream 100 bases:

>100_bases
AATTTACATAATCGGTATTGGTCCTGGAGATGAAAAAAACCGTACTTTAAGAATGCTAGAGGCTATAAAAGAAAGTGACG
TTATAATTGCGTACACGACT

Product: bifunctional sirohydrochlorin cobalt chelatase/precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSNSAIIIITHGSRRNTFVEDMVNLARYIEEKLEVPVFLSHNEYTEPNWRNIVSELLSKGINHIVFALAFLGRGNHVAKD
IMGSFGVSEFYKWVKSTYEGKEINVYFTKPLADSNLVKLALFYRVSTAFPQQENEYIEDPEEIEERTMKFIREKVRERFP
YMGDREIEIIARAVYASGNLDLADKIYISQDAVDIGIESLKTGISILTDVKMVSAGIRWNKVENYLDKASELAKEMRITR
TAAGIRLGLSSPKIVVIGNAPTAVAEVLKIRKEGVEIPLVIATPPGFTNAVEVKEDLIRSGIPCIVLRGTYGGSSIAVSI
INELIRMVRSYGG

Sequences:

>Translated_333_residues
MSNSAIIIITHGSRRNTFVEDMVNLARYIEEKLEVPVFLSHNEYTEPNWRNIVSELLSKGINHIVFALAFLGRGNHVAKD
IMGSFGVSEFYKWVKSTYEGKEINVYFTKPLADSNLVKLALFYRVSTAFPQQENEYIEDPEEIEERTMKFIREKVRERFP
YMGDREIEIIARAVYASGNLDLADKIYISQDAVDIGIESLKTGISILTDVKMVSAGIRWNKVENYLDKASELAKEMRITR
TAAGIRLGLSSPKIVVIGNAPTAVAEVLKIRKEGVEIPLVIATPPGFTNAVEVKEDLIRSGIPCIVLRGTYGGSSIAVSI
INELIRMVRSYGG
>Mature_332_residues
SNSAIIIITHGSRRNTFVEDMVNLARYIEEKLEVPVFLSHNEYTEPNWRNIVSELLSKGINHIVFALAFLGRGNHVAKDI
MGSFGVSEFYKWVKSTYEGKEINVYFTKPLADSNLVKLALFYRVSTAFPQQENEYIEDPEEIEERTMKFIREKVRERFPY
MGDREIEIIARAVYASGNLDLADKIYISQDAVDIGIESLKTGISILTDVKMVSAGIRWNKVENYLDKASELAKEMRITRT
AAGIRLGLSSPKIVVIGNAPTAVAEVLKIRKEGVEIPLVIATPPGFTNAVEVKEDLIRSGIPCIVLRGTYGGSSIAVSII
NELIRMVRSYGG

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 37285; Mature: 37153

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSAIIIITHGSRRNTFVEDMVNLARYIEEKLEVPVFLSHNEYTEPNWRNIVSELLSKG
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHH
INHIVFALAFLGRGNHVAKDIMGSFGVSEFYKWVKSTYEGKEINVYFTKPLADSNLVKLA
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHH
LFYRVSTAFPQQENEYIEDPEEIEERTMKFIREKVRERFPYMGDREIEIIARAVYASGNL
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
DLADKIYISQDAVDIGIESLKTGISILTDVKMVSAGIRWNKVENYLDKASELAKEMRITR
CCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
TAAGIRLGLSSPKIVVIGNAPTAVAEVLKIRKEGVEIPLVIATPPGFTNAVEVKEDLIRS
HHCCEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHC
GIPCIVLRGTYGGSSIAVSIINELIRMVRSYGG
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNSAIIIITHGSRRNTFVEDMVNLARYIEEKLEVPVFLSHNEYTEPNWRNIVSELLSKG
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHH
INHIVFALAFLGRGNHVAKDIMGSFGVSEFYKWVKSTYEGKEINVYFTKPLADSNLVKLA
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHH
LFYRVSTAFPQQENEYIEDPEEIEERTMKFIREKVRERFPYMGDREIEIIARAVYASGNL
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
DLADKIYISQDAVDIGIESLKTGISILTDVKMVSAGIRWNKVENYLDKASELAKEMRITR
CCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
TAAGIRLGLSSPKIVVIGNAPTAVAEVLKIRKEGVEIPLVIATPPGFTNAVEVKEDLIRS
HHCCEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHC
GIPCIVLRGTYGGSSIAVSIINELIRMVRSYGG
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]