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The map label for this gene is ywlC [H]

Identifier: 15921819

GI number: 15921819

Start: 1518949

End: 1520007

Strand: Reverse

Name: ywlC [H]

Synonym: ST1526

Alternate gene names: 15921819

Gene position: 1520007-1518949 (Counterclockwise)

Preceding gene: 15921821

Following gene: 15921818

Centisome position: 56.41

GC content: 35.22

Gene sequence:

>1059_bases
ATGACTCAAATAATTAAGATCGATCCATTGAACCCAGAAATTGATAAAATAAAAATAGCTGCTGATGTTATAAGGAATGG
TGGAACAGTAGCTTTTCCTACAGAAACTGTTTACGGTTTAGGTGCTAATGCTTTTGATGGAAATGCGTGTTTAAAAATAT
TTCAAGCTAAAAACAGACCAGTTGATAACCCACTAATTGTCCATATTGCAGATTTTAACCAGCTGTTTGAAGTTGCTAAA
GATATACCAGATAAAGTATTGGAGATAGCACAAATTGTTTGGCCAGGCCCTCTTACATTTGTTCTAAAAAAGACCGAGAG
AGTTCCTAAAGAAGTTACTGCTGGTCTGGATACTGTTGCCGTTAGGATGCCAGCTCATCCAATAGCATTACAATTAATAC
GTGAGAGCGGGGTTCCAATAGCTGCACCTAGTGCTAATTTAGCTACTAGACCAAGTCCTACAAAGGCTGAAGATGTAATT
GTAGATCTAAATGGAAGGGTAGACGTAATTATCGATGGTGGACATACGTTCTTTGGTGTTGAAAGCACAATAATTAACGT
AACAGTTGAACCACCGGTACTTCTTCGACCTGGACCTTTCACAATTGAGGAACTAAAGAAGCTCTTTGGTGAAATAGTTA
TTCCAGAATTTGCTCAAGGAAAGAAAGAAGCTGAAATAGCCTTAGCACCTGGAATGAAATATAAACATTACGCGCCTAAT
ACAAGATTACTATTAGTAGAAAATAGGAATATATTTAAAGATGTAGTGTCTTTGTTGAGTAAGAAATATAAGGTTGCACT
TCTTATACCTAAAGAACTAAGTAAAGAGTTTGAAGGTTTACAACAAATAATCCTTGGCAGTGATGAAAATTTATACGAAG
TAGCAAGGAATTTATTTGATTCTTTCAGAGAACTAGATAAACTAAACGTTGACTTAGGCATTATGATAGGTTTTCCAGAA
AGAGGAATAGGATTTGCTATCATGAATAGGGCAAGAAAAGCATCAGGCTTTTCAATTATCAAAGCTATTAGTGATGTGTA
TAAGTATGTTAATATTTAA

Upstream 100 bases:

>100_bases
TCAACTAAATCAGTATAGAGCGCCTCAGACATCATAATCCTCAATACTAATTTCTCATCACTGTTTAAATTTAAAAAGTA
GCATACTATTAACATTTTTT

Downstream 100 bases:

>100_bases
GTTTCCTAGTGTAACTTCAACTCAAGATTTAGCTGAAGCAATATATCAAATAATAAACGCAGATGAGTTTGTAATTGTTG
CTGAAGAGCAAACTAGGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTQIIKIDPLNPEIDKIKIAADVIRNGGTVAFPTETVYGLGANAFDGNACLKIFQAKNRPVDNPLIVHIADFNQLFEVAK
DIPDKVLEIAQIVWPGPLTFVLKKTERVPKEVTAGLDTVAVRMPAHPIALQLIRESGVPIAAPSANLATRPSPTKAEDVI
VDLNGRVDVIIDGGHTFFGVESTIINVTVEPPVLLRPGPFTIEELKKLFGEIVIPEFAQGKKEAEIALAPGMKYKHYAPN
TRLLLVENRNIFKDVVSLLSKKYKVALLIPKELSKEFEGLQQIILGSDENLYEVARNLFDSFRELDKLNVDLGIMIGFPE
RGIGFAIMNRARKASGFSIIKAISDVYKYVNI

Sequences:

>Translated_352_residues
MTQIIKIDPLNPEIDKIKIAADVIRNGGTVAFPTETVYGLGANAFDGNACLKIFQAKNRPVDNPLIVHIADFNQLFEVAK
DIPDKVLEIAQIVWPGPLTFVLKKTERVPKEVTAGLDTVAVRMPAHPIALQLIRESGVPIAAPSANLATRPSPTKAEDVI
VDLNGRVDVIIDGGHTFFGVESTIINVTVEPPVLLRPGPFTIEELKKLFGEIVIPEFAQGKKEAEIALAPGMKYKHYAPN
TRLLLVENRNIFKDVVSLLSKKYKVALLIPKELSKEFEGLQQIILGSDENLYEVARNLFDSFRELDKLNVDLGIMIGFPE
RGIGFAIMNRARKASGFSIIKAISDVYKYVNI
>Mature_351_residues
TQIIKIDPLNPEIDKIKIAADVIRNGGTVAFPTETVYGLGANAFDGNACLKIFQAKNRPVDNPLIVHIADFNQLFEVAKD
IPDKVLEIAQIVWPGPLTFVLKKTERVPKEVTAGLDTVAVRMPAHPIALQLIRESGVPIAAPSANLATRPSPTKAEDVIV
DLNGRVDVIIDGGHTFFGVESTIINVTVEPPVLLRPGPFTIEELKKLFGEIVIPEFAQGKKEAEIALAPGMKYKHYAPNT
RLLLVENRNIFKDVVSLLSKKYKVALLIPKELSKEFEGLQQIILGSDENLYEVARNLFDSFRELDKLNVDLGIMIGFPER
GIGFAIMNRARKASGFSIIKAISDVYKYVNI

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI87081864, Length=201, Percent_Identity=29.3532338308458, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367210, Length=151, Percent_Identity=33.7748344370861, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17537239, Length=209, Percent_Identity=30.1435406698565, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321269, Length=408, Percent_Identity=37.0098039215686, Blast_Score=216, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 38803; Mature: 38672

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQIIKIDPLNPEIDKIKIAADVIRNGGTVAFPTETVYGLGANAFDGNACLKIFQAKNRP
CCEEEEECCCCCCHHHEEHHHHHHHCCCEEEECCCHHEECCCCCCCCHHHHEEEHHCCCC
VDNPLIVHIADFNQLFEVAKDIPDKVLEIAQIVWPGPLTFVLKKTERVPKEVTAGLDTVA
CCCCEEEEEECHHHHHHHHHHCHHHHHHHHHHHCCCCHHEEEHHHHHCCHHHHCCCCEEE
VRMPAHPIALQLIRESGVPIAAPSANLATRPSPTKAEDVIVDLNGRVDVIIDGGHTFFGV
EECCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCEEEEE
ESTIINVTVEPPVLLRPGPFTIEELKKLFGEIVIPEFAQGKKEAEIALAPGMKYKHYAPN
EEEEEEEEECCCEEECCCCCCHHHHHHHHHHCCCCHHHCCCCCCEEEECCCCCEEEECCC
TRLLLVENRNIFKDVVSLLSKKYKVALLIPKELSKEFEGLQQIILGSDENLYEVARNLFD
CEEEEEECCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SFRELDKLNVDLGIMIGFPERGIGFAIMNRARKASGFSIIKAISDVYKYVNI
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQIIKIDPLNPEIDKIKIAADVIRNGGTVAFPTETVYGLGANAFDGNACLKIFQAKNRP
CEEEEECCCCCCHHHEEHHHHHHHCCCEEEECCCHHEECCCCCCCCHHHHEEEHHCCCC
VDNPLIVHIADFNQLFEVAKDIPDKVLEIAQIVWPGPLTFVLKKTERVPKEVTAGLDTVA
CCCCEEEEEECHHHHHHHHHHCHHHHHHHHHHHCCCCHHEEEHHHHHCCHHHHCCCCEEE
VRMPAHPIALQLIRESGVPIAAPSANLATRPSPTKAEDVIVDLNGRVDVIIDGGHTFFGV
EECCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCEEEEE
ESTIINVTVEPPVLLRPGPFTIEELKKLFGEIVIPEFAQGKKEAEIALAPGMKYKHYAPN
EEEEEEEEECCCEEECCCCCCHHHHHHHHHHCCCCHHHCCCCCCEEEECCCCCEEEECCC
TRLLLVENRNIFKDVVSLLSKKYKVALLIPKELSKEFEGLQQIILGSDENLYEVARNLFD
CEEEEEECCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SFRELDKLNVDLGIMIGFPERGIGFAIMNRARKASGFSIIKAISDVYKYVNI
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]