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The map label for this gene is purP [H]

Identifier: 15920482

GI number: 15920482

Start: 309208

End: 310254

Strand: Direct

Name: purP [H]

Synonym: ST0290

Alternate gene names: 15920482

Gene position: 309208-310254 (Clockwise)

Preceding gene: 15920481

Following gene: 15920483

Centisome position: 11.47

GC content: 31.04

Gene sequence:

>1047_bases
ATGGTTAGAATAGCTGCTCTTGCAAGTCATTCTGCCCTTGATGTTTTTGATGGAGCTAAAGATGAAAATTTTGAGACTAT
AGCTCTTTGTAAAAAAGGTAGAGAAAGACCTTATTTAGAATTTAAAAGAATCGTAGATGAATGCATCATTTTAGATGATT
TCAAAGAAATAGCTTCAGAAAAAATAGATAGTTACTTAACTTCTAGAGATGCTATAATAATTCCTAACAGAAGTTTAGCA
GTATATGTTGGTTATGATAATCTAGAAAAAATGAGAACTAAATATTTTGGAAATAGAAAGATGTTAAGATGGGAAGAAAG
GACTGGAGAAAAAAATTACTATAAAATATTAGATGAAGCTAAAATCAGAAGACCTAAAATATATAAACCTGAAGAAGTTG
ATGGTGCAGTTATAGTAAAATTACCCGAAGCTAAAAGAAGAGTTGAGAGAGGATTTTTCATTGCTGTTAATAAAAAAGAT
TTTGATGAGAAATTAGATTCCTTAATGAAGGCCGGTATTATAGATGAAAAAAGTGTTAATGAGATGGTAATAGAAGAGTA
TATATTGGGTGCCCATTTTAATATAAACTATTTCTATTCACCAATTTTTAATAGAGTTGAACTTTTAAGCATAGATAGAA
GAATACAGAGCGATCTAGATTCCTTTTACAGATTACCAGCTGAAATACAGCTTAAACTTAATAGATTGCCAAGATTTATA
GAAGTAGGACATGAACCAGCTACTATAAGAGAGAGTTTACTTGAAAAAGTTTTTGAAATTGGATATGCTTTTGTAGAAGC
TACAAAAAAACTAGAACCGCCTGGTATAATAGGGCCCTTTACACTTCAAGCAATGGTTACACCAGAATTAGATTTAGTAG
TATTTGATGTTGCCCCTAGAATAGGCGGCGGTACTAATGCTCATATGGGAATAGGCAGTCAATATTCTAAACTTTATTTC
GGGAAGCCTATTAGTTTAGGTAGAAGGATAGCAATTGAGATAAAAGAAGGAATAAAAAACGGAGAATCTAATAAAATTCT
TACATGA

Upstream 100 bases:

>100_bases
GTTGGCTTTATTGGGATGAACCCATGAGCGTTGGCAGAAGAATCAGTAGAGAGATAAAATTAGCAATAAACTCTAATAAG
TTAGAACAGGTGTTAACATA

Downstream 100 bases:

>100_bases
TAATTATAACGTAACTTACACATAAGACTACCTAATTTCTCAGGTATCTATAATTATAAATCAGTATTAGCTAAGTTTAT
ATATTTTTAAGAGAGATTTA

Product: 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase-like protein

Products: NA

Alternate protein names: 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MVRIAALASHSALDVFDGAKDENFETIALCKKGRERPYLEFKRIVDECIILDDFKEIASEKIDSYLTSRDAIIIPNRSLA
VYVGYDNLEKMRTKYFGNRKMLRWEERTGEKNYYKILDEAKIRRPKIYKPEEVDGAVIVKLPEAKRRVERGFFIAVNKKD
FDEKLDSLMKAGIIDEKSVNEMVIEEYILGAHFNINYFYSPIFNRVELLSIDRRIQSDLDSFYRLPAEIQLKLNRLPRFI
EVGHEPATIRESLLEKVFEIGYAFVEATKKLEPPGIIGPFTLQAMVTPELDLVVFDVAPRIGGGTNAHMGIGSQYSKLYF
GKPISLGRRIAIEIKEGIKNGESNKILT

Sequences:

>Translated_348_residues
MVRIAALASHSALDVFDGAKDENFETIALCKKGRERPYLEFKRIVDECIILDDFKEIASEKIDSYLTSRDAIIIPNRSLA
VYVGYDNLEKMRTKYFGNRKMLRWEERTGEKNYYKILDEAKIRRPKIYKPEEVDGAVIVKLPEAKRRVERGFFIAVNKKD
FDEKLDSLMKAGIIDEKSVNEMVIEEYILGAHFNINYFYSPIFNRVELLSIDRRIQSDLDSFYRLPAEIQLKLNRLPRFI
EVGHEPATIRESLLEKVFEIGYAFVEATKKLEPPGIIGPFTLQAMVTPELDLVVFDVAPRIGGGTNAHMGIGSQYSKLYF
GKPISLGRRIAIEIKEGIKNGESNKILT
>Mature_348_residues
MVRIAALASHSALDVFDGAKDENFETIALCKKGRERPYLEFKRIVDECIILDDFKEIASEKIDSYLTSRDAIIIPNRSLA
VYVGYDNLEKMRTKYFGNRKMLRWEERTGEKNYYKILDEAKIRRPKIYKPEEVDGAVIVKLPEAKRRVERGFFIAVNKKD
FDEKLDSLMKAGIIDEKSVNEMVIEEYILGAHFNINYFYSPIFNRVELLSIDRRIQSDLDSFYRLPAEIQLKLNRLPRFI
EVGHEPATIRESLLEKVFEIGYAFVEATKKLEPPGIIGPFTLQAMVTPELDLVVFDVAPRIGGGTNAHMGIGSQYSKLYF
GKPISLGRRIAIEIKEGIKNGESNKILT

Specific function: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates [H]

COG id: COG1759

COG function: function code R; ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR009720
- InterPro:   IPR010672
- InterPro:   IPR013817 [H]

Pfam domain/function: PF06849 DUF1246; PF06973 DUF1297 [H]

EC number: NA

Molecular weight: Translated: 39929; Mature: 39929

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIAALASHSALDVFDGAKDENFETIALCKKGRERPYLEFKRIVDECIILDDFKEIASE
CEEEEEECCCCCHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KIDSYLTSRDAIIIPNRSLAVYVGYDNLEKMRTKYFGNRKMLRWEERTGEKNYYKILDEA
HHHHHHHCCCEEEECCCCEEEEECCCCHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHHHH
KIRRPKIYKPEEVDGAVIVKLPEAKRRVERGFFIAVNKKDFDEKLDSLMKAGIIDEKSVN
HCCCCCCCCCCCCCCEEEEECCHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCHHH
EMVIEEYILGAHFNINYFYSPIFNRVELLSIDRRIQSDLDSFYRLPAEIQLKLNRLPRFI
HHHHHHHHHCCEEEEEEEHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHCCHHH
EVGHEPATIRESLLEKVFEIGYAFVEATKKLEPPGIIGPFTLQAMVTPELDLVVFDVAPR
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEECCCC
IGGGTNAHMGIGSQYSKLYFGKPISLGRRIAIEIKEGIKNGESNKILT
CCCCCCCCCCCCCCHHHEECCCCCCCCCEEEEEEHHHCCCCCCCCCCC
>Mature Secondary Structure
MVRIAALASHSALDVFDGAKDENFETIALCKKGRERPYLEFKRIVDECIILDDFKEIASE
CEEEEEECCCCCHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KIDSYLTSRDAIIIPNRSLAVYVGYDNLEKMRTKYFGNRKMLRWEERTGEKNYYKILDEA
HHHHHHHCCCEEEECCCCEEEEECCCCHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHHHH
KIRRPKIYKPEEVDGAVIVKLPEAKRRVERGFFIAVNKKDFDEKLDSLMKAGIIDEKSVN
HCCCCCCCCCCCCCCEEEEECCHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCHHH
EMVIEEYILGAHFNINYFYSPIFNRVELLSIDRRIQSDLDSFYRLPAEIQLKLNRLPRFI
HHHHHHHHHCCEEEEEEEHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHCCHHH
EVGHEPATIRESLLEKVFEIGYAFVEATKKLEPPGIIGPFTLQAMVTPELDLVVFDVAPR
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEECCCC
IGGGTNAHMGIGSQYSKLYFGKPISLGRRIAIEIKEGIKNGESNKILT
CCCCCCCCCCCCCCHHHEECCCCCCCCCEEEEEEHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA