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The map label for this gene is soxB [H]

Identifier: 15920314

GI number: 15920314

Start: 155202

End: 156776

Strand: Direct

Name: soxB [H]

Synonym: ST0136

Alternate gene names: 15920314

Gene position: 155202-156776 (Clockwise)

Preceding gene: 15920313

Following gene: 15920315

Centisome position: 5.76

GC content: 35.87

Gene sequence:

>1575_bases
ATGAATATTTGGGAAATTTTGGATAGAATTACAATTTCACTCGTTGAATTTATAAACAAAGCAAAAAAAGTAGTAAACCC
GAAAGATACTGTAGGTTTAGTATGGCTTTATATTTTAGGTTCAGTAACATGGCTCATAATTCTAGGAACTGCTGCTATGA
ATCTAAGAACTTACTTAACGTATGACGCTAACTCACCATCTGTAGGACCTATCTACTATACAATGCTAACAATACACGGA
TGGAGTGCAATGTTGGGATTGGTACCAGACGCTGCTTTAGGAATAATAATATTCTCTATGTATAAAAGTGGACTCTCAGT
AGTTCACAGAAGATTGATTACCGCTATGTTCTGGATTTCTAATTTAGCTCTGGCTTTTGCACTTTTTGGAGGCCCAGATA
CAGCATGGTACATGTATCCTCCACTAGCTATAGAAGATAATGCAGTATTCCAAGCATTTAGACTTTATCACGGTGCAATG
ATGGGGGCTGCTTATTTAGCCTTAGCACTTAACAGTGCTTGTGCTTCAATAGCTGCATTAGTCTTAGTTATTGATGCATA
TCTAACAAAACCAAAAGACAAAAAGATAAACATTTTCGCAGCCTATGGTGTAGCATTTTCTTTAGTTATAGCAATAACAT
TACCAGCATTAACAGCTGCTGAGTTATGGTATACAGCAGCAATATGGTTCCCCAGCCTTGTTAAAGTAAACCCATTACTT
TGGGTTATACTGTTCTGGTTCTATGGACACCCAGTAGTCTATTACGTACCATTCCCCTTATTTGGGGCCTTATACTATTA
TATACCAATTTATGCAAAAAGACCTTTGTTTAGTGAGAAATGGGCAAGATGGAACATATTCCTTTTAGCTATAGGATCAA
TGCTAATATGGGTTCACCACTTACAAACATTTCCATTACCAGTAGATTTAAGAGCATGGATAACTGTATCCACGTTACTA
CTAGCCAGTGGTTCTGGATTAACGGTACTTAATCTAGGTTTAACAATACTAACTTCTAAAGGATATGATTATAAAGATCC
TTTAGGACTAACATTTCTAATTGCATTAATAGGTTTCATAATTGGTGGAGTACAAGCATTACCACAACCTATAAATCTTA
TAAATGGTGTAGTACACAATACATACTACATTGTTGGACATTTCCACCTTATAATCTGGACTCTAATACTTGTAGGATTT
ACTGGAGTATTTCTTGATTTACTTAAAGTTTCTAACCCGAATCTTAACTTTAGTCAAAAAGCTAGAAAACTTATGGTAGC
CGGTTTAATAGTTTGGACAGTACCATTTGTAACAATTGGTTACCTTATGAGTATAGCAGGCTATTTGGGCTTACTAAGAA
GAGTAATTGCTTACCCACCAATGTTTACACCGTATATGGATGGAATGTCATTTTTAGCAGAGATAGGAATACCAGGGTTA
GTAATAACAATTGCCACTGGGATAGCAGAGTATATAAAAACAGCAACACCTTCTACCACTCAAGTTTCTACATTCCCTCC
AAGCAGTTTTACCCTTTCCTTGAATGGAAAGGATATGGTAAAAGAGGTGAAGTAA

Upstream 100 bases:

>100_bases
CGTAACACCCCCGACTCCAGGTAATTTCACTTGGAGGGATTCGGAATATTCCGCATATAATTTCTCTTATTTCACTGGAA
CATTAGAGGTGATGTAAAAA

Downstream 100 bases:

>100_bases
ATGGAGGAGAGACAAGAGAGGAAAGAAGAACAACAACAAAAGAAGTCAGGATTTTTTGATGCAATCCTTGACAGAATAGG
GATAAACGAAGCACCACTAT

Product: quinol oxidase polypeptide I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Oxidase aa(3) subunit 1; Quinol oxidase polypeptide I [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MNIWEILDRITISLVEFINKAKKVVNPKDTVGLVWLYILGSVTWLIILGTAAMNLRTYLTYDANSPSVGPIYYTMLTIHG
WSAMLGLVPDAALGIIIFSMYKSGLSVVHRRLITAMFWISNLALAFALFGGPDTAWYMYPPLAIEDNAVFQAFRLYHGAM
MGAAYLALALNSACASIAALVLVIDAYLTKPKDKKINIFAAYGVAFSLVIAITLPALTAAELWYTAAIWFPSLVKVNPLL
WVILFWFYGHPVVYYVPFPLFGALYYYIPIYAKRPLFSEKWARWNIFLLAIGSMLIWVHHLQTFPLPVDLRAWITVSTLL
LASGSGLTVLNLGLTILTSKGYDYKDPLGLTFLIALIGFIIGGVQALPQPINLINGVVHNTYYIVGHFHLIIWTLILVGF
TGVFLDLLKVSNPNLNFSQKARKLMVAGLIVWTVPFVTIGYLMSIAGYLGLLRRVIAYPPMFTPYMDGMSFLAEIGIPGL
VITIATGIAEYIKTATPSTTQVSTFPPSSFTLSLNGKDMVKEVK

Sequences:

>Translated_524_residues
MNIWEILDRITISLVEFINKAKKVVNPKDTVGLVWLYILGSVTWLIILGTAAMNLRTYLTYDANSPSVGPIYYTMLTIHG
WSAMLGLVPDAALGIIIFSMYKSGLSVVHRRLITAMFWISNLALAFALFGGPDTAWYMYPPLAIEDNAVFQAFRLYHGAM
MGAAYLALALNSACASIAALVLVIDAYLTKPKDKKINIFAAYGVAFSLVIAITLPALTAAELWYTAAIWFPSLVKVNPLL
WVILFWFYGHPVVYYVPFPLFGALYYYIPIYAKRPLFSEKWARWNIFLLAIGSMLIWVHHLQTFPLPVDLRAWITVSTLL
LASGSGLTVLNLGLTILTSKGYDYKDPLGLTFLIALIGFIIGGVQALPQPINLINGVVHNTYYIVGHFHLIIWTLILVGF
TGVFLDLLKVSNPNLNFSQKARKLMVAGLIVWTVPFVTIGYLMSIAGYLGLLRRVIAYPPMFTPYMDGMSFLAEIGIPGL
VITIATGIAEYIKTATPSTTQVSTFPPSSFTLSLNGKDMVKEVK
>Mature_524_residues
MNIWEILDRITISLVEFINKAKKVVNPKDTVGLVWLYILGSVTWLIILGTAAMNLRTYLTYDANSPSVGPIYYTMLTIHG
WSAMLGLVPDAALGIIIFSMYKSGLSVVHRRLITAMFWISNLALAFALFGGPDTAWYMYPPLAIEDNAVFQAFRLYHGAM
MGAAYLALALNSACASIAALVLVIDAYLTKPKDKKINIFAAYGVAFSLVIAITLPALTAAELWYTAAIWFPSLVKVNPLL
WVILFWFYGHPVVYYVPFPLFGALYYYIPIYAKRPLFSEKWARWNIFLLAIGSMLIWVHHLQTFPLPVDLRAWITVSTLL
LASGSGLTVLNLGLTILTSKGYDYKDPLGLTFLIALIGFIIGGVQALPQPINLINGVVHNTYYIVGHFHLIIWTLILVGF
TGVFLDLLKVSNPNLNFSQKARKLMVAGLIVWTVPFVTIGYLMSIAGYLGLLRRVIAYPPMFTPYMDGMSFLAEIGIPGL
VITIATGIAEYIKTATPSTTQVSTFPPSSFTLSLNGKDMVKEVK

Specific function: Subunit I binds heme a and the bimetallic center [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=235, Percent_Identity=26.8085106382979, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1786634, Length=387, Percent_Identity=21.9638242894057, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6226519, Length=245, Percent_Identity=28.9795918367347, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6226524, Length=95, Percent_Identity=32.6315789473684, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.9.3.-

Molecular weight: Translated: 58043; Mature: 58043

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIWEILDRITISLVEFINKAKKVVNPKDTVGLVWLYILGSVTWLIILGTAAMNLRTYLT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEE
YDANSPSVGPIYYTMLTIHGWSAMLGLVPDAALGIIIFSMYKSGLSVVHRRLITAMFWIS
ECCCCCCCCHHEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLALAFALFGGPDTAWYMYPPLAIEDNAVFQAFRLYHGAMMGAAYLALALNSACASIAAL
HHHHHHHHCCCCCCCEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVIDAYLTKPKDKKINIFAAYGVAFSLVIAITLPALTAAELWYTAAIWFPSLVKVNPLL
HHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVILFWFYGHPVVYYVPFPLFGALYYYIPIYAKRPLFSEKWARWNIFLLAIGSMLIWVHH
HHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LQTFPLPVDLRAWITVSTLLLASGSGLTVLNLGLTILTSKGYDYKDPLGLTFLIALIGFI
HHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECEEEEECCCCCCCCCHHHHHHHHHHHHH
IGGVQALPQPINLINGVVHNTYYIVGHFHLIIWTLILVGFTGVFLDLLKVSNPNLNFSQK
HHHHHHCCCHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ARKLMVAGLIVWTVPFVTIGYLMSIAGYLGLLRRVIAYPPMFTPYMDGMSFLAEIGIPGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHH
VITIATGIAEYIKTATPSTTQVSTFPPSSFTLSLNGKDMVKEVK
HHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCHHHHHHCC
>Mature Secondary Structure
MNIWEILDRITISLVEFINKAKKVVNPKDTVGLVWLYILGSVTWLIILGTAAMNLRTYLT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEE
YDANSPSVGPIYYTMLTIHGWSAMLGLVPDAALGIIIFSMYKSGLSVVHRRLITAMFWIS
ECCCCCCCCHHEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLALAFALFGGPDTAWYMYPPLAIEDNAVFQAFRLYHGAMMGAAYLALALNSACASIAAL
HHHHHHHHCCCCCCCEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVIDAYLTKPKDKKINIFAAYGVAFSLVIAITLPALTAAELWYTAAIWFPSLVKVNPLL
HHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVILFWFYGHPVVYYVPFPLFGALYYYIPIYAKRPLFSEKWARWNIFLLAIGSMLIWVHH
HHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LQTFPLPVDLRAWITVSTLLLASGSGLTVLNLGLTILTSKGYDYKDPLGLTFLIALIGFI
HHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECEEEEECCCCCCCCCHHHHHHHHHHHHH
IGGVQALPQPINLINGVVHNTYYIVGHFHLIIWTLILVGFTGVFLDLLKVSNPNLNFSQK
HHHHHHCCCHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ARKLMVAGLIVWTVPFVTIGYLMSIAGYLGLLRRVIAYPPMFTPYMDGMSFLAEIGIPGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHH
VITIATGIAEYIKTATPSTTQVSTFPPSSFTLSLNGKDMVKEVK
HHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1372250 [H]