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The map label for this gene is cutL [H]

Identifier: 15920271

GI number: 15920271

Start: 116017

End: 118305

Strand: Direct

Name: cutL [H]

Synonym: ST0093

Alternate gene names: 15920271

Gene position: 116017-118305 (Clockwise)

Preceding gene: 15920270

Following gene: 15920272

Centisome position: 4.31

GC content: 35.26

Gene sequence:

>2289_bases
ATGTATATTGAAGGATTACGTGCTGTTAATGGTGAAGGAGAATACATAAATGACCTACCAGATTTAGCTGGCACACTATA
CATGGCTATTTACAGAAGTCCCATTGCACACGGAAAAATAAAGAAAATAGATCTTAGCGACGTCAAACTTCACGGTGGTA
TTGCTTTTGGGCCAGAAGAATTAAGTAAAGTTATTGTAAATCCTTTTCCTAATACCGTAGAGTTACCAATAAAATACTAT
CCTTTTGCAAAAGATAAAGTTAGATTTGTTGGTGAACCGATAGCTGTAGTTTTAGCCAAAGATTATTATAAGGCTATTGA
TCTGCTGGATTATATAAACGTTGAAATCGAGGAATTACCACCCGTTATCACAATTGAGGATTCTTTAAAAAATGAGGTTT
TACTACATGAAGAAGTTAAAACGAATATCGCAATGCATAAAATTATGAGATTTGGTAATATAGAAAGAGCTTTTTCCGAA
TCACCTATCGTTATCTCTCATACGTTTAAATTTGGAAGGCATTCAGCATTACCCCTTGAAACTTACGGGGTGTTAGCTAA
ATTTGGTGAAGAGTTAGAGGTTTGGGCAAATATACAAGGACCCATGTTACAAGTCTATTTCTTAAGTAGAGCACTTAATA
TACCTATAAATAAGATTAAATTATTTTCACCCAGAGATATAGGTGGGAGTTTTGGAAACAAATATTCTCTTTATCCATAC
ATTACTTTAGCTGCAGCAGCCTCAAAATTAACGGGAAAACCGATCAGATGGTTTGAAAGTAGAGCTGAGAGTTTTATAGC
CAGTTCAGCTGGAGGGGAAAGAAAAGGAAATGTTGAAATTGCAGCAACAAAAGATGGGGTAATAAAAGGTATACGATACA
CTTTTTATGAAGATGTTGGAGCATACGTTAGACCACCTGAGCCTGGAGTATTATTTAGAGTTCAAGGTAATTTAAACGGG
GCTTACGATATTAGGGCTATTGAAGCCGAATATTATGTAGTTCTAACTAATAAATCTCCTACTGGTTTAAATAGGGGTTA
TGGAGGACCTCCATTTTATTTTGCCTTAGAGACTGCAGTTGATAAACTTGCTGACGAAGTTGGAATTGATCCTTTGGAAT
TAAGGTTAAAGAACTTAATTAAGGTTTTTGACAAAGAGATTAACGGACAAAGATTTTATGAGACTGTTTCTGGAGGACTT
TATCCAGAACAAGACTACGTTAAAGTTGTAAAAGCTATTGAGGATGAGTATAAGAAATGGAAGAGTATGAAAGATGTGGG
AGTTGGCATAGCTGTAATTGTAGAACCTAGTGGAACTAATTTGGCTTATGTAGATTTGGCACTAAATAAGATAAAAAATC
CTCATTCAGCCTCTAGTGACTATGTCACTATAGCTCTTAATCCAGATGGTTCGGTATCTGTATTTGTTAATGGTACTAAT
GAGGGTTTAGGACATGAGACCACAATAGCTGAATTTATTTCAAAAGAACTTGGAATAGATGAAAGTCTTATTCATGTGGA
AAATAGGGTTGATACTACACAGCCTTGGAACTTGGCTAGTGGTAGTTATTCAAGTAGATTTGCACCAATCGTAATGAGTG
CGGTAAAGAGCGGTGTAGATGAGCTTAAGAAAAGATTAGCAGAATTAGCTAAAAAGTATCTAGAAACTGAAGAAATAATA
TTCGAAAATGGAAGATTTTATGATGCTAAGAACAAGGAAAAGTATGTAGATATTAAGAGATTAGTCTCAGCTTACCACTG
GAACCCATCTGAATTTAATTATGATAAAGCTCTCTCTGTTACCTCATACTTTTATTCTCCCCTTCTAAAACCTCCTCAAG
ATAATAAGATAAATTCTTCCTTAGGATATGCTATTCAAGCCCATTTAGCTATTGTAAAAAGGGATGAGGTTACTGGTGAA
TTTAAAATAGTTAAGTACGTTATCTCACATGACGCTGGGAGAATATTAAATAAGAATTTACTTGAAGGGCAAATGTACGG
AGGACTTTTACATGGTATTGCGTTAACATTTTATGAGGAATTGAAATATGATGAAAGAGGAAATCCTTTAGTAACCCTCT
TTGATTCTTATGAATCGCCAACTTTATCTGAAGTTATAGATACACAAGTTGAGTTCATTCATTTTGAAACTCCAGCAAAA
TATATCCCAACCGGTGCATATGGGGGTGGAGAAGGACCAATAATGGCTGCTCCAGCTGCATTGGCTAATGCAATCTCAAG
GCTTATAGGAAAAAGAATAAGTGAAGTGCCTATTAGGGTGATTGAATGA

Upstream 100 bases:

>100_bases
GTTTCAAAGGTTGATGTTAGTAATAAGAAAAATGAGTTAAAGGACGAAAAATATGACCTAAGTAAATTAAGTTTATAAAG
AATGTTTCGCTCTATTTTTT

Downstream 100 bases:

>100_bases
GCTTTGTGTTAGGTATTCCTAAAAAGTTTAAGTACATTAAGGTTAACTCTCTTGATGAAGCCTTAGAGTTACTTAGAGAT
GGATCAAAAGTATTAGCTGG

Product: xanthine dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 762; Mature: 762

Protein sequence:

>762_residues
MYIEGLRAVNGEGEYINDLPDLAGTLYMAIYRSPIAHGKIKKIDLSDVKLHGGIAFGPEELSKVIVNPFPNTVELPIKYY
PFAKDKVRFVGEPIAVVLAKDYYKAIDLLDYINVEIEELPPVITIEDSLKNEVLLHEEVKTNIAMHKIMRFGNIERAFSE
SPIVISHTFKFGRHSALPLETYGVLAKFGEELEVWANIQGPMLQVYFLSRALNIPINKIKLFSPRDIGGSFGNKYSLYPY
ITLAAAASKLTGKPIRWFESRAESFIASSAGGERKGNVEIAATKDGVIKGIRYTFYEDVGAYVRPPEPGVLFRVQGNLNG
AYDIRAIEAEYYVVLTNKSPTGLNRGYGGPPFYFALETAVDKLADEVGIDPLELRLKNLIKVFDKEINGQRFYETVSGGL
YPEQDYVKVVKAIEDEYKKWKSMKDVGVGIAVIVEPSGTNLAYVDLALNKIKNPHSASSDYVTIALNPDGSVSVFVNGTN
EGLGHETTIAEFISKELGIDESLIHVENRVDTTQPWNLASGSYSSRFAPIVMSAVKSGVDELKKRLAELAKKYLETEEII
FENGRFYDAKNKEKYVDIKRLVSAYHWNPSEFNYDKALSVTSYFYSPLLKPPQDNKINSSLGYAIQAHLAIVKRDEVTGE
FKIVKYVISHDAGRILNKNLLEGQMYGGLLHGIALTFYEELKYDERGNPLVTLFDSYESPTLSEVIDTQVEFIHFETPAK
YIPTGAYGGGEGPIMAAPAALANAISRLIGKRISEVPIRVIE

Sequences:

>Translated_762_residues
MYIEGLRAVNGEGEYINDLPDLAGTLYMAIYRSPIAHGKIKKIDLSDVKLHGGIAFGPEELSKVIVNPFPNTVELPIKYY
PFAKDKVRFVGEPIAVVLAKDYYKAIDLLDYINVEIEELPPVITIEDSLKNEVLLHEEVKTNIAMHKIMRFGNIERAFSE
SPIVISHTFKFGRHSALPLETYGVLAKFGEELEVWANIQGPMLQVYFLSRALNIPINKIKLFSPRDIGGSFGNKYSLYPY
ITLAAAASKLTGKPIRWFESRAESFIASSAGGERKGNVEIAATKDGVIKGIRYTFYEDVGAYVRPPEPGVLFRVQGNLNG
AYDIRAIEAEYYVVLTNKSPTGLNRGYGGPPFYFALETAVDKLADEVGIDPLELRLKNLIKVFDKEINGQRFYETVSGGL
YPEQDYVKVVKAIEDEYKKWKSMKDVGVGIAVIVEPSGTNLAYVDLALNKIKNPHSASSDYVTIALNPDGSVSVFVNGTN
EGLGHETTIAEFISKELGIDESLIHVENRVDTTQPWNLASGSYSSRFAPIVMSAVKSGVDELKKRLAELAKKYLETEEII
FENGRFYDAKNKEKYVDIKRLVSAYHWNPSEFNYDKALSVTSYFYSPLLKPPQDNKINSSLGYAIQAHLAIVKRDEVTGE
FKIVKYVISHDAGRILNKNLLEGQMYGGLLHGIALTFYEELKYDERGNPLVTLFDSYESPTLSEVIDTQVEFIHFETPAK
YIPTGAYGGGEGPIMAAPAALANAISRLIGKRISEVPIRVIE
>Mature_762_residues
MYIEGLRAVNGEGEYINDLPDLAGTLYMAIYRSPIAHGKIKKIDLSDVKLHGGIAFGPEELSKVIVNPFPNTVELPIKYY
PFAKDKVRFVGEPIAVVLAKDYYKAIDLLDYINVEIEELPPVITIEDSLKNEVLLHEEVKTNIAMHKIMRFGNIERAFSE
SPIVISHTFKFGRHSALPLETYGVLAKFGEELEVWANIQGPMLQVYFLSRALNIPINKIKLFSPRDIGGSFGNKYSLYPY
ITLAAAASKLTGKPIRWFESRAESFIASSAGGERKGNVEIAATKDGVIKGIRYTFYEDVGAYVRPPEPGVLFRVQGNLNG
AYDIRAIEAEYYVVLTNKSPTGLNRGYGGPPFYFALETAVDKLADEVGIDPLELRLKNLIKVFDKEINGQRFYETVSGGL
YPEQDYVKVVKAIEDEYKKWKSMKDVGVGIAVIVEPSGTNLAYVDLALNKIKNPHSASSDYVTIALNPDGSVSVFVNGTN
EGLGHETTIAEFISKELGIDESLIHVENRVDTTQPWNLASGSYSSRFAPIVMSAVKSGVDELKKRLAELAKKYLETEEII
FENGRFYDAKNKEKYVDIKRLVSAYHWNPSEFNYDKALSVTSYFYSPLLKPPQDNKINSSLGYAIQAHLAIVKRDEVTGE
FKIVKYVISHDAGRILNKNLLEGQMYGGLLHGIALTFYEELKYDERGNPLVTLFDSYESPTLSEVIDTQVEFIHFETPAK
YIPTGAYGGGEGPIMAAPAALANAISRLIGKRISEVPIRVIE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=751, Percent_Identity=25.1664447403462, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI71773480, Length=734, Percent_Identity=24.3869209809264, Blast_Score=144, Evalue=4e-34,
Organism=Escherichia coli, GI1789230, Length=797, Percent_Identity=24.8431618569636, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI1789246, Length=795, Percent_Identity=23.1446540880503, Blast_Score=155, Evalue=9e-39,
Organism=Escherichia coli, GI1786478, Length=639, Percent_Identity=22.2222222222222, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=718, Percent_Identity=22.5626740947075, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=771, Percent_Identity=22.4383916990921, Blast_Score=102, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=752, Percent_Identity=22.3404255319149, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17737937, Length=721, Percent_Identity=23.7170596393897, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24647193, Length=742, Percent_Identity=23.3153638814016, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24647201, Length=754, Percent_Identity=22.4137931034483, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84853; Mature: 84853

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIEGLRAVNGEGEYINDLPDLAGTLYMAIYRSPIAHGKIKKIDLSDVKLHGGIAFGPEE
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECCEEECHHH
LSKVIVNPFPNTVELPIKYYPFAKDKVRFVGEPIAVVLAKDYYKAIDLLDYINVEIEELP
HHHHHCCCCCCCEECCEEECCCCCCHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCHHHCC
PVITIEDSLKNEVLLHEEVKTNIAMHKIMRFGNIERAFSESPIVISHTFKFGRHSALPLE
CEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEECCCCCCCCCHH
TYGVLAKFGEELEVWANIQGPMLQVYFLSRALNIPINKIKLFSPRDIGGSFGNKYSLYPY
HHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEECHH
ITLAAAASKLTGKPIRWFESRAESFIASSAGGERKGNVEIAATKDGVIKGIRYTFYEDVG
HEEHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCC
AYVRPPEPGVLFRVQGNLNGAYDIRAIEAEYYVVLTNKSPTGLNRGYGGPPFYFALETAV
CEECCCCCCEEEEEECCCCCEEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCEEHHHHHH
DKLADEVGIDPLELRLKNLIKVFDKEINGQRFYETVSGGLYPEQDYVKVVKAIEDEYKKW
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
KSMKDVGVGIAVIVEPSGTNLAYVDLALNKIKNPHSASSDYVTIALNPDGSVSVFVNGTN
HHHHHCCCEEEEEECCCCCCEEEEEEEHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCC
EGLGHETTIAEFISKELGIDESLIHVENRVDTTQPWNLASGSYSSRFAPIVMSAVKSGVD
CCCCCHHHHHHHHHHHHCCCHHHEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ELKKRLAELAKKYLETEEIIFENGRFYDAKNKEKYVDIKRLVSAYHWNPSEFNYDKALSV
HHHHHHHHHHHHHHCHHHHEEECCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
TSYFYSPLLKPPQDNKINSSLGYAIQAHLAIVKRDEVTGEFKIVKYVISHDAGRILNKNL
HHHHHHHCCCCCCCCCCCCHHCCEEEEEEEEEECCCCCCCHHEEHHHHHCCCHHHHHHHH
LEGQMYGGLLHGIALTFYEELKYDERGNPLVTLFDSYESPTLSEVIDTQVEFIHFETPAK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHCCEEEEEEECCCC
YIPTGAYGGGEGPIMAAPAALANAISRLIGKRISEVPIRVIE
CCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MYIEGLRAVNGEGEYINDLPDLAGTLYMAIYRSPIAHGKIKKIDLSDVKLHGGIAFGPEE
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECCEEECHHH
LSKVIVNPFPNTVELPIKYYPFAKDKVRFVGEPIAVVLAKDYYKAIDLLDYINVEIEELP
HHHHHCCCCCCCEECCEEECCCCCCHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCHHHCC
PVITIEDSLKNEVLLHEEVKTNIAMHKIMRFGNIERAFSESPIVISHTFKFGRHSALPLE
CEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEECCCCCCCCCHH
TYGVLAKFGEELEVWANIQGPMLQVYFLSRALNIPINKIKLFSPRDIGGSFGNKYSLYPY
HHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEECHH
ITLAAAASKLTGKPIRWFESRAESFIASSAGGERKGNVEIAATKDGVIKGIRYTFYEDVG
HEEHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCC
AYVRPPEPGVLFRVQGNLNGAYDIRAIEAEYYVVLTNKSPTGLNRGYGGPPFYFALETAV
CEECCCCCCEEEEEECCCCCEEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCEEHHHHHH
DKLADEVGIDPLELRLKNLIKVFDKEINGQRFYETVSGGLYPEQDYVKVVKAIEDEYKKW
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
KSMKDVGVGIAVIVEPSGTNLAYVDLALNKIKNPHSASSDYVTIALNPDGSVSVFVNGTN
HHHHHCCCEEEEEECCCCCCEEEEEEEHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCC
EGLGHETTIAEFISKELGIDESLIHVENRVDTTQPWNLASGSYSSRFAPIVMSAVKSGVD
CCCCCHHHHHHHHHHHHCCCHHHEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ELKKRLAELAKKYLETEEIIFENGRFYDAKNKEKYVDIKRLVSAYHWNPSEFNYDKALSV
HHHHHHHHHHHHHHCHHHHEEECCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
TSYFYSPLLKPPQDNKINSSLGYAIQAHLAIVKRDEVTGEFKIVKYVISHDAGRILNKNL
HHHHHHHCCCCCCCCCCCCHHCCEEEEEEEEEECCCCCCCHHEEHHHHHCCCHHHHHHHH
LEGQMYGGLLHGIALTFYEELKYDERGNPLVTLFDSYESPTLSEVIDTQVEFIHFETPAK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHCCEEEEEEECCCC
YIPTGAYGGGEGPIMAAPAALANAISRLIGKRISEVPIRVIE
CCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]