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The map label for this gene is yfhC [C]

Identifier: 15893208

GI number: 15893208

Start: 1191796

End: 1192302

Strand: Reverse

Name: yfhC [C]

Synonym: RC1285

Alternate gene names: 15893208

Gene position: 1192302-1191796 (Counterclockwise)

Preceding gene: 15893209

Following gene: 15893207

Centisome position: 93.97

GC content: 32.94

Gene sequence:

>507_bases
GTGAATATATTGTTAGATAAAGAAGCTAATTTTAATAATTTTTTCATGGAGCAAGCTTTAAAACAAGCAAAGATTGCTTT
TGATAAAAATGAAGTCCCGGTCGGAGCGGTAGTTGTAGATAGGTTACATCAGAAAATTATTGCTAGTACCCATAACAATA
CGGAAGAAAAAAATAACGCTCTTTATCATGCTGAAATTATTGCTATTAATGAAGCATGTAATCTTATATCTTCTAAAAAT
TTAAATGATTATGATATTTACGTTACTTTAGAACCTTGTGCTATGTGTGCGGCAGCTATAGCTCATAGCAGGTTAAAACG
TTTATTTTATGGGGCTTCTGATTCCAAGCACGGAGTAGTCGAAAGTAATTTGCGATATTTTAACAGTAGTGCTTGTTTTC
ATAGACCGGAAATATATAGCGGAATTCTTGCCGAAGATTCGGGGCTATTAATGAAAGAGTTTTTTAAGAGGATAAGAACT
GTTATTTCTAGCCACAGAATGACATAA

Upstream 100 bases:

>100_bases
ATTAGCGATGAGATTGCTTTTGAAATATTGCAGGAATTTCCGGAGGCTGAAATAATTATCCACCAAGATCCTTTTGGAAT
CGAAGAACACGTAAAGTACC

Downstream 100 bases:

>100_bases
AGAAGTAAGAAAACATGCTAAAACTATTAACCCCCTATTATTTTAATAAATTATCAAAGGTTATAATACCTATATTAGCT
ATATCTACTTGCGTAATGAT

Product: cytosine deaminase

Products: uracil; NH3

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MNILLDKEANFNNFFMEQALKQAKIAFDKNEVPVGAVVVDRLHQKIIASTHNNTEEKNNALYHAEIIAINEACNLISSKN
LNDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGVVESNLRYFNSSACFHRPEIYSGILAEDSGLLMKEFFKRIRT
VISSHRMT

Sequences:

>Translated_168_residues
MNILLDKEANFNNFFMEQALKQAKIAFDKNEVPVGAVVVDRLHQKIIASTHNNTEEKNNALYHAEIIAINEACNLISSKN
LNDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGVVESNLRYFNSSACFHRPEIYSGILAEDSGLLMKEFFKRIRT
VISSHRMT
>Mature_168_residues
MNILLDKEANFNNFFMEQALKQAKIAFDKNEVPVGAVVVDRLHQKIIASTHNNTEEKNNALYHAEIIAINEACNLISSKN
LNDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGVVESNLRYFNSSACFHRPEIYSGILAEDSGLLMKEFFKRIRT
VISSHRMT

Specific function: Mutation In This Protein Makes E.Coli Resistant To The Toxic Proteins Encoded By The Gef Gene Family. [C]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=151, Percent_Identity=29.1390728476821, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI145693172, Length=160, Percent_Identity=37.5, Blast_Score=114, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17541138, Length=155, Percent_Identity=31.6129032258064, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=154, Percent_Identity=26.6233766233766, Blast_Score=69, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355527, Length=148, Percent_Identity=33.7837837837838, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.1

Molecular weight: Translated: 19015; Mature: 19015

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILLDKEANFNNFFMEQALKQAKIAFDKNEVPVGAVVVDRLHQKIIASTHNNTEEKNNA
CCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCE
LYHAEIIAINEACNLISSKNLNDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGVV
EEEEEEEEEHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ESNLRYFNSSACFHRPEIYSGILAEDSGLLMKEFFKRIRTVISSHRMT
HHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNILLDKEANFNNFFMEQALKQAKIAFDKNEVPVGAVVVDRLHQKIIASTHNNTEEKNNA
CCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCE
LYHAEIIAINEACNLISSKNLNDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGVV
EEEEEEEEEHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ESNLRYFNSSACFHRPEIYSGILAEDSGLLMKEFFKRIRTVISSHRMT
HHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytosine; H2O

Specific reaction: cytosine + H2O = uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]