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The map label for this gene is alr

Identifier: 41410356

GI number: 41410356

Start: 4727880

End: 4729055

Strand: Direct

Name: alr

Synonym: MAP4258

Alternate gene names: 41410356

Gene position: 4727880-4729055 (Clockwise)

Preceding gene: 41410355

Following gene: 41410357

Centisome position: 97.89

GC content: 71.94

Gene sequence:

>1176_bases
ATGGCCGCCGTGGCCGTTACGCCGATATCCCTGACCCCGGGCGTCCTCGCCGAGGCGCTGGTCGACCTGGGCGCCATCGA
GCACAACGTGCGGCTGCTGTGCGAGCAGGCCCGCGGCGCGCAGGTGATGGCCGTGGTCAAGGCCGACGGCTACGGCCACG
GGGCCGTGCAGACGGCGCGTGCCGCGCTGGCCGCCGGGGCCGCCGAGCTGGGCGTGGCCACCGTCGACGAGGCGCTGGCG
CTGCGCGCCGCGGGGATCAGCGCGCCGGTGCTGGCCTGGCTGCATCCGCCCGGCATCGACTTCCGGCCCGCGCTGCTGGC
CGGCGTGCAGATCGGCCTCTCCTCGCAGCGCCAGCTCGACGAGCTGCTGACCGCGGTGCGCGACACCGGCCGGACCGCCA
CGGTCACCGTCAAGGTCGACACCAGGCTGAACCGCAACGGCGTGCCGCCGGCGCAGTACCCGTCGATGCTGACCGCGCTG
CGCCGCGCCGTCGCCGAGGAGGCCATCGTGCCGCGCGGCCTGATGTCTCACATGGTGTACGCCGACCAACCCGCCAACCC
GGTGAATGACGTTCAGGCGCAACGGTTCACCGACATGCTGGCCCAGGCGCGCGAGCAGGGGGTGCGCTTCGAGGTGGCCC
ACCTGTCGAATTCGTCGGCCACCATGTCGCGTCCCGACCTGGCCTTCGACATGGTGCGCCCGGGTATCGCGGTGTACGGC
CTCAGCCCTGTCCCCGAGCTGGGCGACATGGGCCTGGTGCCCGCGATGACGGTGAAATGTACTGTGGCACTGGTGAAGTC
GATACGTGCGGGGGAAAGCGTGTCATACGGACACACCTGGACGGCGCAGCGCGACACCAACCTGGCGCTGCTGCCGGTGG
GCTACGCCGACGGCATCTTCCGGTCGCTGGGCGGGCGGCTGCAGGTGTCGATCAACGGCCGGCGGCGGCCGGGCGTCGGC
CGGATCTGCATGGACCAGTTCGTCGTCGACCTGGGCCCGGGCCGCCCCGACGTGGCCGAGGGCGACGAGGCGATCCTGTT
CGGGCCGGGCAGCAACGGTGAACCCACCGCCCAGGATTGGGCCGATCTGCTCGGCACCATCCACTACGAAGTGGTGACCA
GCCCCCGCGGGCGGATCACCAGGACCTACCGCGAGGCGCACACCGTTGAGTCCTGA

Upstream 100 bases:

>100_bases
ACTTTGCGCCGAGCGTGCAGCCACGGCGATTTTTTCGCGATTTTTTCGCCATGAGTGCACGTTGGGCACTGGGAGAGAGC
ACGCGCGCGTTTCTGGGACA

Downstream 100 bases:

>100_bases
CCGAACCCGCAAGCGCCACAAGGGCAGGACCTGGCTTGCGGGGGGCGCGGGGGTGACCGCGGTCGCCACCATCGTCGGGG
CCTCGGCCCGCCGGTCCATG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MAAVAVTPISLTPGVLAEALVDLGAIEHNVRLLCEQARGAQVMAVVKADGYGHGAVQTARAALAAGAAELGVATVDEALA
LRAAGISAPVLAWLHPPGIDFRPALLAGVQIGLSSQRQLDELLTAVRDTGRTATVTVKVDTRLNRNGVPPAQYPSMLTAL
RRAVAEEAIVPRGLMSHMVYADQPANPVNDVQAQRFTDMLAQAREQGVRFEVAHLSNSSATMSRPDLAFDMVRPGIAVYG
LSPVPELGDMGLVPAMTVKCTVALVKSIRAGESVSYGHTWTAQRDTNLALLPVGYADGIFRSLGGRLQVSINGRRRPGVG
RICMDQFVVDLGPGRPDVAEGDEAILFGPGSNGEPTAQDWADLLGTIHYEVVTSPRGRITRTYREAHTVES

Sequences:

>Translated_391_residues
MAAVAVTPISLTPGVLAEALVDLGAIEHNVRLLCEQARGAQVMAVVKADGYGHGAVQTARAALAAGAAELGVATVDEALA
LRAAGISAPVLAWLHPPGIDFRPALLAGVQIGLSSQRQLDELLTAVRDTGRTATVTVKVDTRLNRNGVPPAQYPSMLTAL
RRAVAEEAIVPRGLMSHMVYADQPANPVNDVQAQRFTDMLAQAREQGVRFEVAHLSNSSATMSRPDLAFDMVRPGIAVYG
LSPVPELGDMGLVPAMTVKCTVALVKSIRAGESVSYGHTWTAQRDTNLALLPVGYADGIFRSLGGRLQVSINGRRRPGVG
RICMDQFVVDLGPGRPDVAEGDEAILFGPGSNGEPTAQDWADLLGTIHYEVVTSPRGRITRTYREAHTVES
>Mature_390_residues
AAVAVTPISLTPGVLAEALVDLGAIEHNVRLLCEQARGAQVMAVVKADGYGHGAVQTARAALAAGAAELGVATVDEALAL
RAAGISAPVLAWLHPPGIDFRPALLAGVQIGLSSQRQLDELLTAVRDTGRTATVTVKVDTRLNRNGVPPAQYPSMLTALR
RAVAEEAIVPRGLMSHMVYADQPANPVNDVQAQRFTDMLAQAREQGVRFEVAHLSNSSATMSRPDLAFDMVRPGIAVYGL
SPVPELGDMGLVPAMTVKCTVALVKSIRAGESVSYGHTWTAQRDTNLALLPVGYADGIFRSLGGRLQVSINGRRRPGVGR
ICMDQFVVDLGPGRPDVAEGDEAILFGPGSNGEPTAQDWADLLGTIHYEVVTSPRGRITRTYREAHTVES

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=373, Percent_Identity=34.8525469168901, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI1787439, Length=366, Percent_Identity=31.1475409836066, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41344; Mature: 41213

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVAVTPISLTPGVLAEALVDLGAIEHNVRLLCEQARGAQVMAVVKADGYGHGAVQTAR
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHH
AALAAGAAELGVATVDEALALRAAGISAPVLAWLHPPGIDFRPALLAGVQIGLSSQRQLD
HHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCHHHHH
ELLTAVRDTGRTATVTVKVDTRLNRNGVPPAQYPSMLTALRRAVAEEAIVPRGLMSHMVY
HHHHHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHEE
ADQPANPVNDVQAQRFTDMLAQAREQGVRFEVAHLSNSSATMSRPDLAFDMVRPGIAVYG
CCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHCCCEEEEE
LSPVPELGDMGLVPAMTVKCTVALVKSIRAGESVSYGHTWTAQRDTNLALLPVGYADGIF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEECCHHHHHH
RSLGGRLQVSINGRRRPGVGRICMDQFVVDLGPGRPDVAEGDEAILFGPGSNGEPTAQDW
HHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCHHHH
ADLLGTIHYEVVTSPRGRITRTYREAHTVES
HHHHHHEEEEEEECCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
AAVAVTPISLTPGVLAEALVDLGAIEHNVRLLCEQARGAQVMAVVKADGYGHGAVQTAR
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHH
AALAAGAAELGVATVDEALALRAAGISAPVLAWLHPPGIDFRPALLAGVQIGLSSQRQLD
HHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCHHHHH
ELLTAVRDTGRTATVTVKVDTRLNRNGVPPAQYPSMLTALRRAVAEEAIVPRGLMSHMVY
HHHHHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHEE
ADQPANPVNDVQAQRFTDMLAQAREQGVRFEVAHLSNSSATMSRPDLAFDMVRPGIAVYG
CCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHCCCEEEEE
LSPVPELGDMGLVPAMTVKCTVALVKSIRAGESVSYGHTWTAQRDTNLALLPVGYADGIF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEECCHHHHHH
RSLGGRLQVSINGRRRPGVGRICMDQFVVDLGPGRPDVAEGDEAILFGPGSNGEPTAQDW
HHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCHHHH
ADLLGTIHYEVVTSPRGRITRTYREAHTVES
HHHHHHEEEEEEECCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA