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The map label for this gene is katA [H]

Identifier: 41409781

GI number: 41409781

Start: 4091900

End: 4093354

Strand: Direct

Name: katA [H]

Synonym: MAP3683

Alternate gene names: 41409781

Gene position: 4091900-4093354 (Clockwise)

Preceding gene: 41409780

Following gene: 41409782

Centisome position: 84.72

GC content: 66.8

Gene sequence:

>1455_bases
ATGGCGGAGAACCATACGACCACGAATGCGGGTGCGCCGGCGCCCAGTGACGAACTGTCCTTGACGGTGGGCCCCGACGG
GCCGCTCCTGCTGCAGGATTCCTACCTCGTCGAGCAGATGGCGGCGTTCAATCGGGAACGGGTGCCCGAGCGTCAGCCGC
ACGCCAAGGGCGCCGGGGCGTACGGGCGCTTCGAGGTGACGGCCGATGTGAGTGAGTACACCAAGGCGGCCTTCCTGCAG
CCGGGTGCGGTCACCGAGGTGTTCGCCCGTTTCTCGTCGGGCAACAGCGGCGAGCGTGGCAGTGCCGACACGGCCCGCGA
CAACCGCGGGTTTTCGGTGAAGTTTTACACCACCGAAGGCAATTTCGACCTCGTCGGCAGCGACGTCCCGGTCTTCGCGA
TCCGGGATCCGATGAAGTTTCCCAACCTGATTCGCGCCGGGGGCCGCCGCGCGGACAACGACCTGCACGACCACAACATG
GTGTGGGATTTCTGGACGAGCTGTCCCGAGACAGCGCACCTGGTGACCCTGGTGATGGGGGACCGGGGCATCCCCAGGAC
GTTTCGGCACATGAACGGCTTCGGCCTGCACGCGTTCAGTTGGGTCAATTCGGCCGGCGAGATCCATTGGGTGAAGTACC
ACTTCAAAACCGACCAGGGCATCCAATGGTTGCCCCAGGAAGAGGGTCGGCGGCTGGCCGGCACCCATCCCGACTGCTGC
GTGCGCGACCTGTACGAGGCCATCGCGCGCGGGAAGTATCCGAGCTGGTCGCTGCAGGTGCAGTTGATGCCGTTCGCCGA
CGCGAAAACCTACCGCTTCAACCCCTTTGACGTGACGAAGGTGTGGCCGCACGCCGACTACCCACCCATCGAGATCGGCA
CGATGACGTTGGACCGCAACGTCACCGATCACCACGCCGAGGTCGAGCAGGCCGCCTTCGCGCCGAGCAACCTGGTGCCC
GGCACCGGGCTGAGCCCCGACAGGCTCTTGTTGGGCCGCAGTTTCGCCTACCCCGATGCGCACCGCGCCCGCATCGGGGT
CAACCACGACCAGCTCCCGGTCAACGCCGCCCGGTGTGCGGTGCGCTCGTACGCCAAGGACGGCCGGATGCGGTTTGTCA
ACACCGCCGACCCGGTGTATGCGCCCAACTCCGCGGGCGGGCCGCAGGCCGATCCCGCACGGGCCGGCGAGGTGCACTGG
GCCGCCGACGGGCAGATGCTGCGCGCGGCGTACACTCTGCGCCGCGACGATGACGACTGGGGCCAGGCCGGCACCCTGGT
GCGCCGGGTGATGGACGATTCGCAACGGGAACGCCTGGTACACAACATCGTTGGTCACGTCTCGGCGGGTGTGAATGAAC
CCGTCCTGTCCCGTGTCTTCGCGTACTGGCGCCACGTCGACGCCGACATCGGCAGGAAGGTCGAAGAAGGCGTTCGCGCC
AATCTCAACAGCTGA

Upstream 100 bases:

>100_bases
TACTGGTACAACATCGACGCCGACATCGGCAAGAGGGTGGAAGACGGCATCCGAGCCGCCAACCTCGGCCGGTGAGCCGG
AAGCCGCCGGACCGCACGAT

Downstream 100 bases:

>100_bases
CAACATCGCGAGACCCTGATTCGTTTGCAGCGCAACGAATCACGTGCCGGCGCGCCCGGGGGATCCGCGTCGGCGGCGCG
CTTGTAGCGACCACCAAAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MAENHTTTNAGAPAPSDELSLTVGPDGPLLLQDSYLVEQMAAFNRERVPERQPHAKGAGAYGRFEVTADVSEYTKAAFLQ
PGAVTEVFARFSSGNSGERGSADTARDNRGFSVKFYTTEGNFDLVGSDVPVFAIRDPMKFPNLIRAGGRRADNDLHDHNM
VWDFWTSCPETAHLVTLVMGDRGIPRTFRHMNGFGLHAFSWVNSAGEIHWVKYHFKTDQGIQWLPQEEGRRLAGTHPDCC
VRDLYEAIARGKYPSWSLQVQLMPFADAKTYRFNPFDVTKVWPHADYPPIEIGTMTLDRNVTDHHAEVEQAAFAPSNLVP
GTGLSPDRLLLGRSFAYPDAHRARIGVNHDQLPVNAARCAVRSYAKDGRMRFVNTADPVYAPNSAGGPQADPARAGEVHW
AADGQMLRAAYTLRRDDDDWGQAGTLVRRVMDDSQRERLVHNIVGHVSAGVNEPVLSRVFAYWRHVDADIGRKVEEGVRA
NLNS

Sequences:

>Translated_484_residues
MAENHTTTNAGAPAPSDELSLTVGPDGPLLLQDSYLVEQMAAFNRERVPERQPHAKGAGAYGRFEVTADVSEYTKAAFLQ
PGAVTEVFARFSSGNSGERGSADTARDNRGFSVKFYTTEGNFDLVGSDVPVFAIRDPMKFPNLIRAGGRRADNDLHDHNM
VWDFWTSCPETAHLVTLVMGDRGIPRTFRHMNGFGLHAFSWVNSAGEIHWVKYHFKTDQGIQWLPQEEGRRLAGTHPDCC
VRDLYEAIARGKYPSWSLQVQLMPFADAKTYRFNPFDVTKVWPHADYPPIEIGTMTLDRNVTDHHAEVEQAAFAPSNLVP
GTGLSPDRLLLGRSFAYPDAHRARIGVNHDQLPVNAARCAVRSYAKDGRMRFVNTADPVYAPNSAGGPQADPARAGEVHW
AADGQMLRAAYTLRRDDDDWGQAGTLVRRVMDDSQRERLVHNIVGHVSAGVNEPVLSRVFAYWRHVDADIGRKVEEGVRA
NLNS
>Mature_483_residues
AENHTTTNAGAPAPSDELSLTVGPDGPLLLQDSYLVEQMAAFNRERVPERQPHAKGAGAYGRFEVTADVSEYTKAAFLQP
GAVTEVFARFSSGNSGERGSADTARDNRGFSVKFYTTEGNFDLVGSDVPVFAIRDPMKFPNLIRAGGRRADNDLHDHNMV
WDFWTSCPETAHLVTLVMGDRGIPRTFRHMNGFGLHAFSWVNSAGEIHWVKYHFKTDQGIQWLPQEEGRRLAGTHPDCCV
RDLYEAIARGKYPSWSLQVQLMPFADAKTYRFNPFDVTKVWPHADYPPIEIGTMTLDRNVTDHHAEVEQAAFAPSNLVPG
TGLSPDRLLLGRSFAYPDAHRARIGVNHDQLPVNAARCAVRSYAKDGRMRFVNTADPVYAPNSAGGPQADPARAGEVHWA
ADGQMLRAAYTLRRDDDDWGQAGTLVRRVMDDSQRERLVHNIVGHVSAGVNEPVLSRVFAYWRHVDADIGRKVEEGVRAN
LNS

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=447, Percent_Identity=48.5458612975391, Blast_Score=426, Evalue=1e-119,
Organism=Escherichia coli, GI48994891, Length=397, Percent_Identity=41.3098236775819, Blast_Score=288, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI71998444, Length=484, Percent_Identity=44.2148760330579, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI25147792, Length=472, Percent_Identity=44.4915254237288, Blast_Score=387, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI25151141, Length=472, Percent_Identity=44.2796610169491, Blast_Score=386, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6320462, Length=485, Percent_Identity=39.7938144329897, Blast_Score=338, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6321525, Length=510, Percent_Identity=34.3137254901961, Blast_Score=290, Evalue=2e-79,
Organism=Drosophila melanogaster, GI17981717, Length=475, Percent_Identity=46.1052631578947, Blast_Score=416, Evalue=1e-116,
Organism=Drosophila melanogaster, GI19920968, Length=482, Percent_Identity=41.9087136929461, Blast_Score=390, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 53707; Mature: 53576

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENHTTTNAGAPAPSDELSLTVGPDGPLLLQDSYLVEQMAAFNRERVPERQPHAKGAGA
CCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YGRFEVTADVSEYTKAAFLQPGAVTEVFARFSSGNSGERGSADTARDNRGFSVKFYTTEG
CCEEEEEECHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECC
NFDLVGSDVPVFAIRDPMKFPNLIRAGGRRADNDLHDHNMVWDFWTSCPETAHLVTLVMG
CEEEECCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCHHEEEEEEEC
DRGIPRTFRHMNGFGLHAFSWVNSAGEIHWVKYHFKTDQGIQWLPQEEGRRLAGTHPDCC
CCCCCHHHHHCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHCCCEECCCCCHHH
VRDLYEAIARGKYPSWSLQVQLMPFADAKTYRFNPFDVTKVWPHADYPPIEIGTMTLDRN
HHHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCCCEEEEECCCCCCCCCEEEEEEECCC
VTDHHAEVEQAAFAPSNLVPGTGLSPDRLLLGRSFAYPDAHRARIGVNHDQLPVNAARCA
CCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCHHEEECCCCCCCCCHHHHHH
VRSYAKDGRMRFVNTADPVYAPNSAGGPQADPARAGEVHWAADGQMLRAAYTLRRDDDDW
HHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEHHHHHCCCCCCH
GQAGTLVRRVMDDSQRERLVHNIVGHVSAGVNEPVLSRVFAYWRHVDADIGRKVEEGVRA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHC
NLNS
CCCC
>Mature Secondary Structure 
AENHTTTNAGAPAPSDELSLTVGPDGPLLLQDSYLVEQMAAFNRERVPERQPHAKGAGA
CCCCCCCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YGRFEVTADVSEYTKAAFLQPGAVTEVFARFSSGNSGERGSADTARDNRGFSVKFYTTEG
CCEEEEEECHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECC
NFDLVGSDVPVFAIRDPMKFPNLIRAGGRRADNDLHDHNMVWDFWTSCPETAHLVTLVMG
CEEEECCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCHHEEEEEEEC
DRGIPRTFRHMNGFGLHAFSWVNSAGEIHWVKYHFKTDQGIQWLPQEEGRRLAGTHPDCC
CCCCCHHHHHCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHCCCEECCCCCHHH
VRDLYEAIARGKYPSWSLQVQLMPFADAKTYRFNPFDVTKVWPHADYPPIEIGTMTLDRN
HHHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCCCEEEEECCCCCCCCCEEEEEEECCC
VTDHHAEVEQAAFAPSNLVPGTGLSPDRLLLGRSFAYPDAHRARIGVNHDQLPVNAARCA
CCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCHHEEECCCCCCCCCHHHHHH
VRSYAKDGRMRFVNTADPVYAPNSAGGPQADPARAGEVHWAADGQMLRAAYTLRRDDDDW
HHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEHHHHHCCCCCCH
GQAGTLVRRVMDDSQRERLVHNIVGHVSAGVNEPVLSRVFAYWRHVDADIGRKVEEGVRA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHC
NLNS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1426241; 12454454 [H]