Click here to switch to the map view.

The map label for this gene is katA [H]

Identifier: 41409780

GI number: 41409780

Start: 4090417

End: 4091874

Strand: Direct

Name: katA [H]

Synonym: MAP3682

Alternate gene names: 41409780

Gene position: 4090417-4091874 (Clockwise)

Preceding gene: 41409779

Following gene: 41409781

Centisome position: 84.69

GC content: 64.68

Gene sequence:

>1458_bases
ATGACGGAGAATTTCACGACGACGAATGCGGGCGCCCCGGCGCCCAGCGACGAACTGTCGTTGACGCTGGGTCCCGATGG
CCCGGTACTGCTGCAGGATTTCTATCTCATCGAGCAGTTGGCCGCGTTCAACCGCGAGCGGGTCCCCGAGCGCCAGCCGC
ACGCCAAGGGGACCGGCGCGTTCGGCCGGTTCGAGGTCACCAATGACCTGAGCGCCTACACCAAAGCCGCGGTGTTTCAG
CCGGGCACCAAGACCGACGTGTTCGTGCGGCTGTCGGGGAACGCCGGCGAGCGCGGCAGCGCCGACACCGTGCGGGACAC
GCGCGGGTTTTCGGTGAAGTTCTACACCACCGAGGGCAACTTCGACCTCGTCGGCCTCGACTTCCCGGTCTTCGTCATCC
GGGACCCGATCAAGTTCCCGCAGATGGTCCGCTCGGCCAAACGCCGCGCGAACAACGACTGCCGTGACCACAACATGCAG
TGGGATTTTTGGACGCTCTCCCCGGAGTCGGCGCACCAGGTGGCCATGATCATGAGCGATCGCGGTATTCCCAAGACGTT
TCGTCACATGCACGGCTTCGGCCTGCACACCTTCAGCTTCCTCAACGCCGCCGGCGAGATCTCGTGGGTGAAGTTTCATT
TCAAGTCCAATCAGGGCATCGAATGGTTGACCCAGGAAGAGGGCGATCGGCTGGCCGGCACCGACCCGGACTACTGCATC
CGGGATCTGTACGAGGCGATCGAGCGCGGGGACCATCCGAGCTGGTCGGTGAAGGTGCAGATCATGCCGTTCGAGGAGGC
CAAGACGTATCGGTTCAACCCGTTCGACGTGACCAAGGTGTGGCCGCATGCCGACTATCCGCTCATCGATCTGGGCACCA
TGACGCTGGACCGCAACGTCACCGACCACCACACCGAGGTCGAGCAGGTGACCTTCGCGCCGCATGCGCTGGTGCCCGGG
ATCGGGCTGAGCCCGGACAAGCTTTTGCTGGGGCGCAGTTTCGCCTACGCCGACGCGCACCGCTACCGGGTCGGGGCCAA
TCACAACCAAATTCCGGTCAACGCCCCGCGGTGTCCGGTGCGCAGCTATTCCAAGGACGGACAGATGCGCTTCGTCAACT
CCACCGACCCGGTGTATGCGCCCAACTCCTACGGCGGGCCGAAGGCCGATCCCGACCGGGCGTCCGTGGTGAAATGGGCC
GTCGACGGCGGAATGATGGTGCGCGCGCCCTACACGCTGCGACCAGACGACGACGACTGGGGCCAGGCCGGCGCCCTGGT
GCGCGACGTGATGGACGACGCCGAGCGGGAACGACTGGTGCACAACATCGTTCACCATGTCACCGACGGCGTGAAAGAAC
CCGTGCTGTCACGCGTCGTCGAATACTGGTACAACATCGACGCCGACATCGGCAAGAGGGTGGAAGACGGCATCCGAGCC
GCCAACCTCGGCCGGTGA

Upstream 100 bases:

>100_bases
TCGTATCGAAAGTTCCAGTAGCGGACCGCTCGTCGACGACGGCGGCGGGGCCGCCGAATTTCTTTGATTGCCCACTGATT
TCGAGCTAGGGAGGACACTG

Downstream 100 bases:

>100_bases
GCCGGAAGCCGCCGGACCGCACGATATGGCGGAGAACCATACGACCACGAATGCGGGTGCGCCGGCGCCCAGTGACGAAC
TGTCCTTGACGGTGGGCCCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTENFTTTNAGAPAPSDELSLTLGPDGPVLLQDFYLIEQLAAFNRERVPERQPHAKGTGAFGRFEVTNDLSAYTKAAVFQ
PGTKTDVFVRLSGNAGERGSADTVRDTRGFSVKFYTTEGNFDLVGLDFPVFVIRDPIKFPQMVRSAKRRANNDCRDHNMQ
WDFWTLSPESAHQVAMIMSDRGIPKTFRHMHGFGLHTFSFLNAAGEISWVKFHFKSNQGIEWLTQEEGDRLAGTDPDYCI
RDLYEAIERGDHPSWSVKVQIMPFEEAKTYRFNPFDVTKVWPHADYPLIDLGTMTLDRNVTDHHTEVEQVTFAPHALVPG
IGLSPDKLLLGRSFAYADAHRYRVGANHNQIPVNAPRCPVRSYSKDGQMRFVNSTDPVYAPNSYGGPKADPDRASVVKWA
VDGGMMVRAPYTLRPDDDDWGQAGALVRDVMDDAERERLVHNIVHHVTDGVKEPVLSRVVEYWYNIDADIGKRVEDGIRA
ANLGR

Sequences:

>Translated_485_residues
MTENFTTTNAGAPAPSDELSLTLGPDGPVLLQDFYLIEQLAAFNRERVPERQPHAKGTGAFGRFEVTNDLSAYTKAAVFQ
PGTKTDVFVRLSGNAGERGSADTVRDTRGFSVKFYTTEGNFDLVGLDFPVFVIRDPIKFPQMVRSAKRRANNDCRDHNMQ
WDFWTLSPESAHQVAMIMSDRGIPKTFRHMHGFGLHTFSFLNAAGEISWVKFHFKSNQGIEWLTQEEGDRLAGTDPDYCI
RDLYEAIERGDHPSWSVKVQIMPFEEAKTYRFNPFDVTKVWPHADYPLIDLGTMTLDRNVTDHHTEVEQVTFAPHALVPG
IGLSPDKLLLGRSFAYADAHRYRVGANHNQIPVNAPRCPVRSYSKDGQMRFVNSTDPVYAPNSYGGPKADPDRASVVKWA
VDGGMMVRAPYTLRPDDDDWGQAGALVRDVMDDAERERLVHNIVHHVTDGVKEPVLSRVVEYWYNIDADIGKRVEDGIRA
ANLGR
>Mature_484_residues
TENFTTTNAGAPAPSDELSLTLGPDGPVLLQDFYLIEQLAAFNRERVPERQPHAKGTGAFGRFEVTNDLSAYTKAAVFQP
GTKTDVFVRLSGNAGERGSADTVRDTRGFSVKFYTTEGNFDLVGLDFPVFVIRDPIKFPQMVRSAKRRANNDCRDHNMQW
DFWTLSPESAHQVAMIMSDRGIPKTFRHMHGFGLHTFSFLNAAGEISWVKFHFKSNQGIEWLTQEEGDRLAGTDPDYCIR
DLYEAIERGDHPSWSVKVQIMPFEEAKTYRFNPFDVTKVWPHADYPLIDLGTMTLDRNVTDHHTEVEQVTFAPHALVPGI
GLSPDKLLLGRSFAYADAHRYRVGANHNQIPVNAPRCPVRSYSKDGQMRFVNSTDPVYAPNSYGGPKADPDRASVVKWAV
DGGMMVRAPYTLRPDDDDWGQAGALVRDVMDDAERERLVHNIVHHVTDGVKEPVLSRVVEYWYNIDADIGKRVEDGIRAA
NLGR

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=473, Percent_Identity=47.7801268498943, Blast_Score=444, Evalue=1e-125,
Organism=Escherichia coli, GI48994891, Length=390, Percent_Identity=43.3333333333333, Blast_Score=308, Evalue=7e-85,
Organism=Caenorhabditis elegans, GI71998444, Length=476, Percent_Identity=45.3781512605042, Blast_Score=420, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI25147792, Length=469, Percent_Identity=46.0554371002132, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI25151141, Length=472, Percent_Identity=45.7627118644068, Blast_Score=406, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6320462, Length=490, Percent_Identity=41.0204081632653, Blast_Score=356, Evalue=4e-99,
Organism=Saccharomyces cerevisiae, GI6321525, Length=507, Percent_Identity=37.0808678500986, Blast_Score=315, Evalue=1e-86,
Organism=Drosophila melanogaster, GI17981717, Length=483, Percent_Identity=45.5486542443064, Blast_Score=437, Evalue=1e-123,
Organism=Drosophila melanogaster, GI19920968, Length=483, Percent_Identity=43.8923395445135, Blast_Score=431, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54519; Mature: 54387

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENFTTTNAGAPAPSDELSLTLGPDGPVLLQDFYLIEQLAAFNRERVPERQPHAKGTGA
CCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
FGRFEVTNDLSAYTKAAVFQPGTKTDVFVRLSGNAGERGSADTVRDTRGFSVKFYTTEGN
CEEEEECCCHHHHHHHHEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCC
FDLVGLDFPVFVIRDPIKFPQMVRSAKRRANNDCRDHNMQWDFWTLSPESAHQVAMIMSD
EEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCHHHCCCEEEEEECCCCCCCEEEEEECC
RGIPKTFRHMHGFGLHTFSFLNAAGEISWVKFHFKSNQGIEWLTQEEGDRLAGTDPDYCI
CCCCHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEECCCCCEEEECCCCCCCCCCCHHHHH
RDLYEAIERGDHPSWSVKVQIMPFEEAKTYRFNPFDVTKVWPHADYPLIDLGTMTLDRNV
HHHHHHHHCCCCCCEEEEEEEEECCCCCCEECCCCEEEEECCCCCCCEEEECEEEECCCC
TDHHTEVEQVTFAPHALVPGIGLSPDKLLLGRSFAYADAHRYRVGANHNQIPVNAPRCPV
CCCCCCHHHEEECCHHHCCCCCCCCCCEECCCCCHHCCCCEEEECCCCCCCCCCCCCCCC
RSYSKDGQMRFVNSTDPVYAPNSYGGPKADPDRASVVKWAVDGGMMVRAPYTLRPDDDDW
CCCCCCCCEEEECCCCCEECCCCCCCCCCCCCHHHEEEEEECCCEEEECCEEECCCCCCC
GQAGALVRDVMDDAERERLVHNIVHHVTDGVKEPVLSRVVEYWYNIDADIGKRVEDGIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ANLGR
HCCCC
>Mature Secondary Structure 
TENFTTTNAGAPAPSDELSLTLGPDGPVLLQDFYLIEQLAAFNRERVPERQPHAKGTGA
CCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
FGRFEVTNDLSAYTKAAVFQPGTKTDVFVRLSGNAGERGSADTVRDTRGFSVKFYTTEGN
CEEEEECCCHHHHHHHHEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCC
FDLVGLDFPVFVIRDPIKFPQMVRSAKRRANNDCRDHNMQWDFWTLSPESAHQVAMIMSD
EEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCHHHCCCEEEEEECCCCCCCEEEEEECC
RGIPKTFRHMHGFGLHTFSFLNAAGEISWVKFHFKSNQGIEWLTQEEGDRLAGTDPDYCI
CCCCHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEECCCCCEEEECCCCCCCCCCCHHHHH
RDLYEAIERGDHPSWSVKVQIMPFEEAKTYRFNPFDVTKVWPHADYPLIDLGTMTLDRNV
HHHHHHHHCCCCCCEEEEEEEEECCCCCCEECCCCEEEEECCCCCCCEEEECEEEECCCC
TDHHTEVEQVTFAPHALVPGIGLSPDKLLLGRSFAYADAHRYRVGANHNQIPVNAPRCPV
CCCCCCHHHEEECCHHHCCCCCCCCCCEECCCCCHHCCCCEEEECCCCCCCCCCCCCCCC
RSYSKDGQMRFVNSTDPVYAPNSYGGPKADPDRASVVKWAVDGGMMVRAPYTLRPDDDDW
CCCCCCCCEEEECCCCCEECCCCCCCCCCCCCHHHEEEEEECCCEEEECCEEECCCCCCC
GQAGALVRDVMDDAERERLVHNIVHHVTDGVKEPVLSRVVEYWYNIDADIGKRVEDGIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ANLGR
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1426241; 12454454 [H]