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The map label for this gene is betA [C]

Identifier: 41409782

GI number: 41409782

Start: 4093517

End: 4095373

Strand: Direct

Name: betA [C]

Synonym: MAP3684

Alternate gene names: 41409782

Gene position: 4093517-4095373 (Clockwise)

Preceding gene: 41409781

Following gene: 41409786

Centisome position: 84.76

GC content: 64.78

Gene sequence:

>1857_bases
ATGCTGCTAACTGCGGGTCGGAATCCGTATCCCGGTAGGCAACGAGGGTTTCCACGCGTGCGGTGCGGCCCGCTGAACAC
CCGAGTTTTCGAGGAGGAAATCATGTCACACGCGCAACCAAATGTCGTCGACGGGGCTCACTTTGACTTCGTCGTCGTCG
GGGGCGGCACCGCGGGTAACGTCGTCGCCGGACGCCTCGCCGAGAACCCGAACGTCAGCGTCCTGGTCGTCGAGGCCGGT
GTCGGTAACCCCTGGGAGCTTGACGGGGTGAACACCCCGGGAACGGCCATGGAGCTGCGCCACAGCCCGTACGACTGGGA
TTACCTGGCCAAGTTCGTCGACCGTGGCGTCTGGCAGCGCATCGACAAGCAGGAGACCCGGGGCAAGATCCTCGGCGGCA
GCTCCGCGGCCAACTACTTCAGCTGGATTCCCGGCTGCAAGCCGACCTACGACCGGTGGGCGGAATACGGTGGCCCGGAA
TGGACCTGGCAGCCGCTGCTTCCCTACCTGCGCAAGAGCGCCACCTATCACGACGACCACGGGACGTTCTCGCCCGACAT
GAAGCGGATCGGCGCCGGCGGTCCGCTGCCCATCTCGCACAACAACATCCCCGAGTTGCAGCCCTTCCGCGACGTCGTCG
CGCAGGCGTGGAAGTCGCGGGGCCTGCCGGTGACGGAGAACATCTACGACGGTGAGATGAACGGCCTCACCCACGCGGTC
AGCACCATCTATCGGGGTGTGCGTTCCGGCAGCTACCTGTTCGTGAAGGACCGGCCCAACATCACGATCCTGCCCGAGGT
TCGGTCCAAGCGGCTGATCATCGACTATGCCGACCGCACCTGCAAGGGTGTGACCGTCATCGACGCCTCCGGCACCGAGC
GCAGCTTCTACGCCAACCGGGAGGTCATCCTCTCCCAGGGTGTTTTCGAGAGCCCGAAGCTGTTGATGCTCAGCGGTATC
GGCCCCGGACGCGAGCTGGCCAAGCACGGCATCCCCGTGGTCGTCGATTCTCGCCATGTCGGCCAGCACCTGTTCGATCA
CCCGGGCGTCCCGTTCGTGCTGCGGATCAAGGAGGGCTACGCCATCGACGACTACCTGCGCCCCGGTGCGAAGCACGACT
CCGCCGTTGCCGATTACCAGAAGGACCACCAGGGTCCGCTGGGCTCCGGTCTGCTGGAGATGATCGGCTTCCCCCGCGTG
GACGAATACCTGGATCGGGATCCGATTTACCGTGAGGCCAAGGCCGCCAACGGCGGGCTCGACCCCTTCTCGCCGGAGGG
ACAGCCGCACTTCGAGCTCGACTTCGTTCCCGCGTTCGGCAGTGCGTTCCAGTGGCAGTACCCCACCCCGCCGGAGGGCG
ACCACATCACCGTGATGGTCGACCTGGTCCGCCCGGCCTACGACGGCGGCGGCGAGGTGACACTCAACAGCACCGACCCG
TTCATGCAGCCCAACCTCAACCTGAATTACCTGTCCAACGAGCTCGACATCATCGCCCTGCGCGAGGGCATCAGGCTGGC
CTACGACATTCTCACCAAGGGCGACGGCTTCAAGGACCTCGTCATCAGCCAGTACCCGTGGGATATGCCGCTGCACTCCG
ACGAGCTGATGAGGACGTCCATCCAGGACCGGGTGCAGACGTCCTACCACCCGTGCGGCACCAACCGGCTGTCCAAGAAC
ATCGACCAAGGCGTGGTGGATCCCAAGCTGAAGGTCCACGGCGTCAACAAACTCCGCGTTGTCGACGCCTCCGTCTTCCC
GATCATCCCGGACTGCCGCATCCAGAACACCGTGTACATGGTCGGCGAGAAGGGCGCGGACGCGATCAAGGCCGACCACA
CGGACCTGTACAAGTAG

Upstream 100 bases:

>100_bases
ATCCGCGTCGGCGGCGCGCTTGTAGCGACCACCAAAGCGCGGCGGGAATTTCGGCCGAATTACGGAGTGAACTACATGGA
GTTCAACGCGGCGCCCGAAC

Downstream 100 bases:

>100_bases
GGGCCGGGGGCTTCGGCCTGGAGTGTGTACTCATGGCGAGATTCCGGCCGAAATCCCGCCGTGAGTACACACTGAAATCC
CTAGCTACACACTCGAATTC

Product: hypothetical protein

Products: NA

Alternate protein names: SDH [H]

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MLLTAGRNPYPGRQRGFPRVRCGPLNTRVFEEEIMSHAQPNVVDGAHFDFVVVGGGTAGNVVAGRLAENPNVSVLVVEAG
VGNPWELDGVNTPGTAMELRHSPYDWDYLAKFVDRGVWQRIDKQETRGKILGGSSAANYFSWIPGCKPTYDRWAEYGGPE
WTWQPLLPYLRKSATYHDDHGTFSPDMKRIGAGGPLPISHNNIPELQPFRDVVAQAWKSRGLPVTENIYDGEMNGLTHAV
STIYRGVRSGSYLFVKDRPNITILPEVRSKRLIIDYADRTCKGVTVIDASGTERSFYANREVILSQGVFESPKLLMLSGI
GPGRELAKHGIPVVVDSRHVGQHLFDHPGVPFVLRIKEGYAIDDYLRPGAKHDSAVADYQKDHQGPLGSGLLEMIGFPRV
DEYLDRDPIYREAKAANGGLDPFSPEGQPHFELDFVPAFGSAFQWQYPTPPEGDHITVMVDLVRPAYDGGGEVTLNSTDP
FMQPNLNLNYLSNELDIIALREGIRLAYDILTKGDGFKDLVISQYPWDMPLHSDELMRTSIQDRVQTSYHPCGTNRLSKN
IDQGVVDPKLKVHGVNKLRVVDASVFPIIPDCRIQNTVYMVGEKGADAIKADHTDLYK

Sequences:

>Translated_618_residues
MLLTAGRNPYPGRQRGFPRVRCGPLNTRVFEEEIMSHAQPNVVDGAHFDFVVVGGGTAGNVVAGRLAENPNVSVLVVEAG
VGNPWELDGVNTPGTAMELRHSPYDWDYLAKFVDRGVWQRIDKQETRGKILGGSSAANYFSWIPGCKPTYDRWAEYGGPE
WTWQPLLPYLRKSATYHDDHGTFSPDMKRIGAGGPLPISHNNIPELQPFRDVVAQAWKSRGLPVTENIYDGEMNGLTHAV
STIYRGVRSGSYLFVKDRPNITILPEVRSKRLIIDYADRTCKGVTVIDASGTERSFYANREVILSQGVFESPKLLMLSGI
GPGRELAKHGIPVVVDSRHVGQHLFDHPGVPFVLRIKEGYAIDDYLRPGAKHDSAVADYQKDHQGPLGSGLLEMIGFPRV
DEYLDRDPIYREAKAANGGLDPFSPEGQPHFELDFVPAFGSAFQWQYPTPPEGDHITVMVDLVRPAYDGGGEVTLNSTDP
FMQPNLNLNYLSNELDIIALREGIRLAYDILTKGDGFKDLVISQYPWDMPLHSDELMRTSIQDRVQTSYHPCGTNRLSKN
IDQGVVDPKLKVHGVNKLRVVDASVFPIIPDCRIQNTVYMVGEKGADAIKADHTDLYK
>Mature_618_residues
MLLTAGRNPYPGRQRGFPRVRCGPLNTRVFEEEIMSHAQPNVVDGAHFDFVVVGGGTAGNVVAGRLAENPNVSVLVVEAG
VGNPWELDGVNTPGTAMELRHSPYDWDYLAKFVDRGVWQRIDKQETRGKILGGSSAANYFSWIPGCKPTYDRWAEYGGPE
WTWQPLLPYLRKSATYHDDHGTFSPDMKRIGAGGPLPISHNNIPELQPFRDVVAQAWKSRGLPVTENIYDGEMNGLTHAV
STIYRGVRSGSYLFVKDRPNITILPEVRSKRLIIDYADRTCKGVTVIDASGTERSFYANREVILSQGVFESPKLLMLSGI
GPGRELAKHGIPVVVDSRHVGQHLFDHPGVPFVLRIKEGYAIDDYLRPGAKHDSAVADYQKDHQGPLGSGLLEMIGFPRV
DEYLDRDPIYREAKAANGGLDPFSPEGQPHFELDFVPAFGSAFQWQYPTPPEGDHITVMVDLVRPAYDGGGEVTLNSTDP
FMQPNLNLNYLSNELDIIALREGIRLAYDILTKGDGFKDLVISQYPWDMPLHSDELMRTSIQDRVQTSYHPCGTNRLSKN
IDQGVVDPKLKVHGVNKLRVVDASVFPIIPDCRIQNTVYMVGEKGADAIKADHTDLYK

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=576, Percent_Identity=29.8611111111111, Blast_Score=181, Evalue=2e-45,
Organism=Escherichia coli, GI1786503, Length=578, Percent_Identity=28.719723183391, Blast_Score=184, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17532301, Length=588, Percent_Identity=27.2108843537415, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24642048, Length=596, Percent_Identity=31.8791946308725, Blast_Score=219, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24642055, Length=626, Percent_Identity=30.0319488817891, Blast_Score=218, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24642042, Length=587, Percent_Identity=32.0272572402044, Blast_Score=215, Evalue=8e-56,
Organism=Drosophila melanogaster, GI24642059, Length=624, Percent_Identity=31.5705128205128, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24642051, Length=587, Percent_Identity=29.9829642248722, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI45549471, Length=614, Percent_Identity=30.1302931596091, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI45551458, Length=609, Percent_Identity=30.5418719211823, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI18859993, Length=607, Percent_Identity=29.8187808896211, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24642039, Length=615, Percent_Identity=29.1056910569106, Blast_Score=199, Evalue=6e-51,
Organism=Drosophila melanogaster, GI24642037, Length=614, Percent_Identity=29.3159609120521, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI18859995, Length=600, Percent_Identity=29, Blast_Score=196, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24642035, Length=623, Percent_Identity=29.8555377207063, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24650267, Length=612, Percent_Identity=29.2483660130719, Blast_Score=172, Evalue=7e-43,
Organism=Drosophila melanogaster, GI17137792, Length=588, Percent_Identity=27.2108843537415, Blast_Score=169, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24642057, Length=605, Percent_Identity=27.4380165289256, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24645930, Length=589, Percent_Identity=27.1646859083192, Blast_Score=114, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.32 [H]

Molecular weight: Translated: 68675; Mature: 68675

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTAGRNPYPGRQRGFPRVRCGPLNTRVFEEEIMSHAQPNVVDGAHFDFVVVGGGTAGN
CEECCCCCCCCCHHCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCC
VVAGRLAENPNVSVLVVEAGVGNPWELDGVNTPGTAMELRHSPYDWDYLAKFVDRGVWQR
CEEHEECCCCCEEEEEEECCCCCCEEECCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHH
IDKQETRGKILGGSSAANYFSWIPGCKPTYDRWAEYGGPEWTWQPLLPYLRKSATYHDDH
HHHHHHCCEEECCCCHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCEECCC
GTFSPDMKRIGAGGPLPISHNNIPELQPFRDVVAQAWKSRGLPVTENIYDGEMNGLTHAV
CCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
STIYRGVRSGSYLFVKDRPNITILPEVRSKRLIIDYADRTCKGVTVIDASGTERSFYANR
HHHHHHHCCCCEEEEECCCCEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCEECCCC
EVILSQGVFESPKLLMLSGIGPGRELAKHGIPVVVDSRHVGQHLFDHPGVPFVLRIKEGY
EEEEECCCCCCCCEEEEECCCCHHHHHHCCCCEEECCHHHHHHHHCCCCCCEEEEECCCC
AIDDYLRPGAKHDSAVADYQKDHQGPLGSGLLEMIGFPRVDEYLDRDPIYREAKAANGGL
EEHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCCCHHHHHHCCCCC
DPFSPEGQPHFELDFVPAFGSAFQWQYPTPPEGDHITVMVDLVRPAYDGGGEVTLNSTDP
CCCCCCCCCCEEEEEECCCCCCEECCCCCCCCCCEEEEEEEEECCCCCCCCEEEECCCCC
FMQPNLNLNYLSNELDIIALREGIRLAYDILTKGDGFKDLVISQYPWDMPLHSDELMRTS
CCCCCCCEEEECCCCEEEEEHHCHHEEHHHHHCCCCHHHHEECCCCCCCCCCHHHHHHHH
IQDRVQTSYHPCGTNRLSKNIDQGVVDPKLKVHGVNKLRVVDASVFPIIPDCRIQNTVYM
HHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCCCCEECCEEEE
VGEKGADAIKADHTDLYK
EECCCCCCCCCCCHHCCC
>Mature Secondary Structure
MLLTAGRNPYPGRQRGFPRVRCGPLNTRVFEEEIMSHAQPNVVDGAHFDFVVVGGGTAGN
CEECCCCCCCCCHHCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCC
VVAGRLAENPNVSVLVVEAGVGNPWELDGVNTPGTAMELRHSPYDWDYLAKFVDRGVWQR
CEEHEECCCCCEEEEEEECCCCCCEEECCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHH
IDKQETRGKILGGSSAANYFSWIPGCKPTYDRWAEYGGPEWTWQPLLPYLRKSATYHDDH
HHHHHHCCEEECCCCHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCEECCC
GTFSPDMKRIGAGGPLPISHNNIPELQPFRDVVAQAWKSRGLPVTENIYDGEMNGLTHAV
CCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
STIYRGVRSGSYLFVKDRPNITILPEVRSKRLIIDYADRTCKGVTVIDASGTERSFYANR
HHHHHHHCCCCEEEEECCCCEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCEECCCC
EVILSQGVFESPKLLMLSGIGPGRELAKHGIPVVVDSRHVGQHLFDHPGVPFVLRIKEGY
EEEEECCCCCCCCEEEEECCCCHHHHHHCCCCEEECCHHHHHHHHCCCCCCEEEEECCCC
AIDDYLRPGAKHDSAVADYQKDHQGPLGSGLLEMIGFPRVDEYLDRDPIYREAKAANGGL
EEHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCCCHHHHHHCCCCC
DPFSPEGQPHFELDFVPAFGSAFQWQYPTPPEGDHITVMVDLVRPAYDGGGEVTLNSTDP
CCCCCCCCCCEEEEEECCCCCCEECCCCCCCCCCEEEEEEEEECCCCCCCCEEEECCCCC
FMQPNLNLNYLSNELDIIALREGIRLAYDILTKGDGFKDLVISQYPWDMPLHSDELMRTS
CCCCCCCEEEECCCCEEEEEHHCHHEEHHHHHCCCCHHHHEECCCCCCCCCCHHHHHHHH
IQDRVQTSYHPCGTNRLSKNIDQGVVDPKLKVHGVNKLRVVDASVFPIIPDCRIQNTVYM
HHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCCCCEECCEEEE
VGEKGADAIKADHTDLYK
EECCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9023923 [H]