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The map label for this gene is ygjG [C]

Identifier: 41409545

GI number: 41409545

Start: 3825978

End: 3827291

Strand: Direct

Name: ygjG [C]

Synonym: MAP3447

Alternate gene names: 41409545

Gene position: 3825978-3827291 (Clockwise)

Preceding gene: 41409543

Following gene: 41409546

Centisome position: 79.22

GC content: 68.65

Gene sequence:

>1314_bases
CTGCACTTCGCCCGGCACGGCCCGGACATCACGCCGCCGATCATCACCCGCGGCCACGGCGTCACCATCTACGACGACCG
CGGCAACAGCTACCTCGACGGCCTGTCCGGGCTGTTCACCGTGCAGGTCGGCCACGGCCGCGCCGAACTCGCCGAGGCCG
CCGCCCGGCAGGCGGGCACGCTGGCGTTCTTCCCGCTGTGGGGGTACGCCACGCCGCCCGCGATCGAGCTCGCCGAGCGG
CTGGCCGGCTACGCCCCGGGCGATTTGAACCGGGTGTTCTTCACCACCGGAGGCACCGAGGCCGTCGAGACGGCGTGGAA
GCTGGCCAAGCAGTACTTCAAGCTCACCGGCAAACCCGGTAAGCACAAAGTGATTTCGCGCGCGGTCGCCTACCACGGCA
CCACCCAGGGCGCGCTGGCGATCACCGGCCTGCCGCGCTACAAGGCGCCGTTCGAGCCGGTGACGCCCGGCGGGTTCCGG
GTGCCTAACACCAACTTCTACCGGGCACCCGAAGCATTCGCCAACGACCCCAAGGGTTTTGGGCTGTGGGCGGCGGACCG
GATCGCCGAGGCGATCGAGTTCGAGGGCCCCGACACCGTGGCCGCGGTGTTCGTCGAACCGGTGCAGAACGCGGGCGGCA
GCATCCCGCCGCCCCCAGGCTATTTCGAGCGGGTCCGCGAAATCTGCGACCGCTACGACGTGCTGCTGGTCTCCGACGAG
GTGATCTGCGCGTTCGGCCGGATCGGCTCGATGTTCGCCTGTGCCGACTTCGGCTATGTGCCCGACATGATCACCTGCGC
CAAGGGCATGACGTCGGGCTACTCGCCGATCGGCGCGATGATCGCCAGCGAGAGGTTGTTCGAGCCGTTCGACGACGGCG
ACACCATGTTCCCGCACGGCTATACCTTTGGCGGCCACCCGGTTTCGGCGGCGGTCGGGCTGGTCAACCTCGACATCTTC
GAGCGCGAGGGGCTCAACGACCGGGTCAGGACCCTGGCGCCGACATTCCGCGCCACTCTGGAAAAGCTGTACGACCTGCC
CATCGTCGGCGACGTCCGCGGCGAGGGCTTCTTCTACGGCGTGGAACTGGTCAAGGATCGGGCCACCAAGCAGACCTTCA
CCGATTCCGAACGCCGCGCGCTGCTGGGACGGGTCGGTGCCGCGCTGTTCGAGGCCGGATTGTATTGCCGTACCGACGAT
CGCGGCGATTCCGTCATCCAGCTGGCGCCGCCGCTGATCAGCGGTCAGGCCGAGTTCGACACCATCGAGGCGGCGCTGCG
CGGCGTGCTCAGCGACGAGTGCCGCCGGCTGTAG

Upstream 100 bases:

>100_bases
CGTCCTGCCCGTGCCGGCGCAGCCACGCGTCCTGGACGATGTCCTCGGCGTCGGCGACCGTACCGGTCAGCCGGTAGGCG
ACCGACATGAGCACCTCTGG

Downstream 100 bases:

>100_bases
CCAGCACCCGCTTGACCTCGTAGGCGGCCAACAGCACCTCGCGGGAATGCGCCGCCGACGGGCTGTTCGCGATCCGCGAT
TGCGCGTTGCACAGCCAGGT

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MHFARHGPDITPPIITRGHGVTIYDDRGNSYLDGLSGLFTVQVGHGRAELAEAAARQAGTLAFFPLWGYATPPAIELAER
LAGYAPGDLNRVFFTTGGTEAVETAWKLAKQYFKLTGKPGKHKVISRAVAYHGTTQGALAITGLPRYKAPFEPVTPGGFR
VPNTNFYRAPEAFANDPKGFGLWAADRIAEAIEFEGPDTVAAVFVEPVQNAGGSIPPPPGYFERVREICDRYDVLLVSDE
VICAFGRIGSMFACADFGYVPDMITCAKGMTSGYSPIGAMIASERLFEPFDDGDTMFPHGYTFGGHPVSAAVGLVNLDIF
EREGLNDRVRTLAPTFRATLEKLYDLPIVGDVRGEGFFYGVELVKDRATKQTFTDSERRALLGRVGAALFEAGLYCRTDD
RGDSVIQLAPPLISGQAEFDTIEAALRGVLSDECRRL

Sequences:

>Translated_437_residues
MHFARHGPDITPPIITRGHGVTIYDDRGNSYLDGLSGLFTVQVGHGRAELAEAAARQAGTLAFFPLWGYATPPAIELAER
LAGYAPGDLNRVFFTTGGTEAVETAWKLAKQYFKLTGKPGKHKVISRAVAYHGTTQGALAITGLPRYKAPFEPVTPGGFR
VPNTNFYRAPEAFANDPKGFGLWAADRIAEAIEFEGPDTVAAVFVEPVQNAGGSIPPPPGYFERVREICDRYDVLLVSDE
VICAFGRIGSMFACADFGYVPDMITCAKGMTSGYSPIGAMIASERLFEPFDDGDTMFPHGYTFGGHPVSAAVGLVNLDIF
EREGLNDRVRTLAPTFRATLEKLYDLPIVGDVRGEGFFYGVELVKDRATKQTFTDSERRALLGRVGAALFEAGLYCRTDD
RGDSVIQLAPPLISGQAEFDTIEAALRGVLSDECRRL
>Mature_437_residues
MHFARHGPDITPPIITRGHGVTIYDDRGNSYLDGLSGLFTVQVGHGRAELAEAAARQAGTLAFFPLWGYATPPAIELAER
LAGYAPGDLNRVFFTTGGTEAVETAWKLAKQYFKLTGKPGKHKVISRAVAYHGTTQGALAITGLPRYKAPFEPVTPGGFR
VPNTNFYRAPEAFANDPKGFGLWAADRIAEAIEFEGPDTVAAVFVEPVQNAGGSIPPPPGYFERVREICDRYDVLLVSDE
VICAFGRIGSMFACADFGYVPDMITCAKGMTSGYSPIGAMIASERLFEPFDDGDTMFPHGYTFGGHPVSAAVGLVNLDIF
EREGLNDRVRTLAPTFRATLEKLYDLPIVGDVRGEGFFYGVELVKDRATKQTFTDSERRALLGRVGAALFEAGLYCRTDD
RGDSVIQLAPPLISGQAEFDTIEAALRGVLSDECRRL

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI24119277, Length=435, Percent_Identity=29.8850574712644, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI37574042, Length=412, Percent_Identity=28.8834951456311, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI13994255, Length=446, Percent_Identity=26.6816143497758, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI226442705, Length=412, Percent_Identity=28.8834951456311, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI226442709, Length=381, Percent_Identity=28.8713910761155, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI4557809, Length=434, Percent_Identity=27.1889400921659, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI284507298, Length=337, Percent_Identity=28.486646884273, Blast_Score=115, Evalue=5e-26,
Organism=Escherichia coli, GI145693181, Length=352, Percent_Identity=35.2272727272727, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1789759, Length=412, Percent_Identity=30.8252427184466, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1788044, Length=413, Percent_Identity=28.8135593220339, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789016, Length=364, Percent_Identity=29.6703296703297, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1786991, Length=425, Percent_Identity=28, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787560, Length=423, Percent_Identity=29.3144208037825, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786349, Length=330, Percent_Identity=27.8787878787879, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=31.2785388127854, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI25144271, Length=436, Percent_Identity=25.9174311926606, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71992977, Length=443, Percent_Identity=26.410835214447, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=304, Percent_Identity=26.3157894736842, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17541228, Length=450, Percent_Identity=22.6666666666667, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=364, Percent_Identity=29.1208791208791, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6323470, Length=432, Percent_Identity=26.3888888888889, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324386, Length=341, Percent_Identity=27.8592375366569, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI161085790, Length=449, Percent_Identity=29.6213808463252, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI28574759, Length=377, Percent_Identity=31.2997347480106, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21356575, Length=432, Percent_Identity=28.2407407407407, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI21357415, Length=434, Percent_Identity=26.7281105990783, Blast_Score=138, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 47383; Mature: 47383

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFARHGPDITPPIITRGHGVTIYDDRGNSYLDGLSGLFTVQVGHGRAELAEAAARQAGT
CCCCCCCCCCCCCCEECCCCEEEEECCCCCHHHCCCCEEEEEECCCHHHHHHHHHHHCCC
LAFFPLWGYATPPAIELAERLAGYAPGDLNRVFFTTGGTEAVETAWKLAKQYFKLTGKPG
EEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
KHKVISRAVAYHGTTQGALAITGLPRYKAPFEPVTPGGFRVPNTNFYRAPEAFANDPKGF
HHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCEECCCCCCEECCHHHCCCCCCC
GLWAADRIAEAIEFEGPDTVAAVFVEPVQNAGGSIPPPPGYFERVREICDRYDVLLVSDE
CCHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEECCH
VICAFGRIGSMFACADFGYVPDMITCAKGMTSGYSPIGAMIASERLFEPFDDGDTMFPHG
HHHHHHHHCCCHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
YTFGGHPVSAAVGLVNLDIFEREGLNDRVRTLAPTFRATLEKLYDLPIVGDVRGEGFFYG
CCCCCCHHHHHHHEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEH
VELVKDRATKQTFTDSERRALLGRVGAALFEAGLYCRTDDRGDSVIQLAPPLISGQAEFD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEECCCCCCCCCHHH
TIEAALRGVLSDECRRL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHFARHGPDITPPIITRGHGVTIYDDRGNSYLDGLSGLFTVQVGHGRAELAEAAARQAGT
CCCCCCCCCCCCCCEECCCCEEEEECCCCCHHHCCCCEEEEEECCCHHHHHHHHHHHCCC
LAFFPLWGYATPPAIELAERLAGYAPGDLNRVFFTTGGTEAVETAWKLAKQYFKLTGKPG
EEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
KHKVISRAVAYHGTTQGALAITGLPRYKAPFEPVTPGGFRVPNTNFYRAPEAFANDPKGF
HHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCEECCCCCCEECCHHHCCCCCCC
GLWAADRIAEAIEFEGPDTVAAVFVEPVQNAGGSIPPPPGYFERVREICDRYDVLLVSDE
CCHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEECCH
VICAFGRIGSMFACADFGYVPDMITCAKGMTSGYSPIGAMIASERLFEPFDDGDTMFPHG
HHHHHHHHCCCHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
YTFGGHPVSAAVGLVNLDIFEREGLNDRVRTLAPTFRATLEKLYDLPIVGDVRGEGFFYG
CCCCCCHHHHHHHEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEH
VELVKDRATKQTFTDSERRALLGRVGAALFEAGLYCRTDDRGDSVIQLAPPLISGQAEFD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEECCCCCCCCCHHH
TIEAALRGVLSDECRRL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]