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The map label for this gene is omt

Identifier: 41409314

GI number: 41409314

Start: 3567488

End: 3568318

Strand: Direct

Name: omt

Synonym: MAP3216

Alternate gene names: 41409314

Gene position: 3567488-3568318 (Clockwise)

Preceding gene: 41409312

Following gene: 41409319

Centisome position: 73.86

GC content: 64.5

Gene sequence:

>831_bases
ATGGGAATTGACACCAGCGCCATCACCCCGGAGGAAGAGACCGCATTTTTGACGTTGCAGGCCCGCGCGATCAACAACGG
GTGGGCACGCCCCATCCTGCCCGACCCGGGCGCCGCCGATGCCGTGACAAAGATCGACTACGACTTCGACGGCCTGGGGC
TCGTGACGCCCGTCGTTTGTCAAACATCCCTGCGCGCAAAACTTCTCGACGACCGGGTGCGCGCGTTCATCGCCCAACAC
GCCGATGCCGTGGTGGTCGATCTGGGCGCCGGGCTCGACGACGGGTACGCCCGTGTCAAGCCGCCGGACACCGTCGACTG
GTACAGCGTCGAGCTGCCCGGGCTGGCGGCCCTGCGCGACAAGGTGATGCCACCGGGACCTCACGAACACACCATCGGAA
TCTCCGTGACCGATCCCGAGTGGATATCGGCGATTCCGGCGGACCGCCCCGCCATCGTCATCGCCGACGGATTGTTCCCC
TTCCTCAACAAGGAGCAGATCATCGCGGTGATGCGCGCGATCACCGATCACTTCCCCGCCGGACAGCTGGCGTTCAACGA
CTACGGACGCATGGTGATTGGCGTGTGGATCTCGAAGTTGTTCCCGCAGCGGATGTTCAAGAAGGTGAACCAGCTCCGTG
CGTTCGAGGGTTACAACGACCCGCACACGCCGGAACGCTGGAACCCCAAACTCACCCTCGTCGAGGAGACCAGCCTGGCG
AGTGTGCCCGAGGTGGACCTGTTCCCGACGTGGTTGCGGATCGCGACACGGATGGCCGGGTGGAGCAAGCGGACGGCACG
GTCCGCGCGCATCCTCAGGTTCAGCTTTTAG

Upstream 100 bases:

>100_bases
CGTCGGGATCTGTCGTGGTCATTGCGTCAGACTATACGATTGGACAATAAACTACACAGATGTATAGTCGGGGCAAACCG
GAGTTCAGGGAGGCACGGAT

Downstream 100 bases:

>100_bases
CGCCTTCCGCGCGTCGGGGGTGCCGCTCCGGTCGCGTCGTGCGGCCGGCGCCGGCGGTCAGCTCAGGAACGGCCGGATGG
CCAGCAGGTAGATCGCCAGC

Product: Omt

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MGIDTSAITPEEETAFLTLQARAINNGWARPILPDPGAADAVTKIDYDFDGLGLVTPVVCQTSLRAKLLDDRVRAFIAQH
ADAVVVDLGAGLDDGYARVKPPDTVDWYSVELPGLAALRDKVMPPGPHEHTIGISVTDPEWISAIPADRPAIVIADGLFP
FLNKEQIIAVMRAITDHFPAGQLAFNDYGRMVIGVWISKLFPQRMFKKVNQLRAFEGYNDPHTPERWNPKLTLVEETSLA
SVPEVDLFPTWLRIATRMAGWSKRTARSARILRFSF

Sequences:

>Translated_276_residues
MGIDTSAITPEEETAFLTLQARAINNGWARPILPDPGAADAVTKIDYDFDGLGLVTPVVCQTSLRAKLLDDRVRAFIAQH
ADAVVVDLGAGLDDGYARVKPPDTVDWYSVELPGLAALRDKVMPPGPHEHTIGISVTDPEWISAIPADRPAIVIADGLFP
FLNKEQIIAVMRAITDHFPAGQLAFNDYGRMVIGVWISKLFPQRMFKKVNQLRAFEGYNDPHTPERWNPKLTLVEETSLA
SVPEVDLFPTWLRIATRMAGWSKRTARSARILRFSF
>Mature_275_residues
GIDTSAITPEEETAFLTLQARAINNGWARPILPDPGAADAVTKIDYDFDGLGLVTPVVCQTSLRAKLLDDRVRAFIAQHA
DAVVVDLGAGLDDGYARVKPPDTVDWYSVELPGLAALRDKVMPPGPHEHTIGISVTDPEWISAIPADRPAIVIADGLFPF
LNKEQIIAVMRAITDHFPAGQLAFNDYGRMVIGVWISKLFPQRMFKKVNQLRAFEGYNDPHTPERWNPKLTLVEETSLAS
VPEVDLFPTWLRIATRMAGWSKRTARSARILRFSF

Specific function: O-methyltransferase that catalyzes the methylation of the C-9 carboxy group of tetracenomycin E (TCM E) to yield TCM A2. Catalyzes as well the following side reactions:methylation of 8- O-methyl-TCM D3 to 9-carboxymethyl-8-O-methyl-TCM D3; and of TCM B3 t

COG id: COG3315

COG function: function code Q; O-Methyltransferase involved in polyketide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007213
- InterPro:   IPR016874 [H]

Pfam domain/function: PF04072 LCM [H]

EC number: NA

Molecular weight: Translated: 30587; Mature: 30456

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIDTSAITPEEETAFLTLQARAINNGWARPILPDPGAADAVTKIDYDFDGLGLVTPVVC
CCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHH
QTSLRAKLLDDRVRAFIAQHADAVVVDLGAGLDDGYARVKPPDTVDWYSVELPGLAALRD
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHH
KVMPPGPHEHTIGISVTDPEWISAIPADRPAIVIADGLFPFLNKEQIIAVMRAITDHFPA
CCCCCCCCCCEEEEEECCHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
GQLAFNDYGRMVIGVWISKLFPQRMFKKVNQLRAFEGYNDPHTPERWNPKLTLVEETSLA
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCC
SVPEVDLFPTWLRIATRMAGWSKRTARSARILRFSF
CCCCCCCHHHHHHHHHHHCCCCHHHHHHEEEEEECC
>Mature Secondary Structure 
GIDTSAITPEEETAFLTLQARAINNGWARPILPDPGAADAVTKIDYDFDGLGLVTPVVC
CCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHH
QTSLRAKLLDDRVRAFIAQHADAVVVDLGAGLDDGYARVKPPDTVDWYSVELPGLAALRD
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHH
KVMPPGPHEHTIGISVTDPEWISAIPADRPAIVIADGLFPFLNKEQIIAVMRAITDHFPA
CCCCCCCCCCEEEEEECCHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
GQLAFNDYGRMVIGVWISKLFPQRMFKKVNQLRAFEGYNDPHTPERWNPKLTLVEETSLA
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCC
SVPEVDLFPTWLRIATRMAGWSKRTARSARILRFSF
CCCCCCCHHHHHHHHHHHCCCCHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8509339 [H]