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The map label for this gene is nuoB

Identifier: 41409300

GI number: 41409300

Start: 3551715

End: 3552269

Strand: Direct

Name: nuoB

Synonym: MAP3202

Alternate gene names: 41409300

Gene position: 3551715-3552269 (Clockwise)

Preceding gene: 41409299

Following gene: 41409301

Centisome position: 73.54

GC content: 65.77

Gene sequence:

>555_bases
GTGGGTCTTGAGGAACAGCTGCCCGGCGGGATCCTGTTGTCGACGGTCGAGAAGGTCGCCGGCTACGTCCGCAAGAACTC
GCTGTGGCCGGCGACGTTCGGGTTGGCCTGCTGTGCCATCGAGATGATGGCAACCGCCGGGCCAAGATTCGACATCGCGC
GGTTCGGCATGGAGCGGTTCTCGGCCACTCCCCGCCAGGCTGACCTGATGATCGTCGCCGGTCGGGTGAGCCAGAAGATG
GCCCCGGTGCTGCGCCAGATCTACGACCAGATGGCCGAGCCGAAATGGGTGCTGGCCATGGGGGTGTGCGCGTCATCCGG
CGGGATGTTCAACAACTACGCGATCGTGCAGGGCGTCGACCACGTCGTCCCGGTGGACATCTACCTGCCCGGCTGCCCCC
CGCGCCCGGAAATGCTGTTGTACGCAATCCTCAAGCTGCACGAGAAGATTCAACAGATGCCGCTGGGCGTCAACCGGGAA
ACCGCCATCGCCGAAGCCGAGCAGGCGGCGCTGTCGGCCCGGCCCACCATCGAGATGCGCGGACTGCTGCGATGA

Upstream 100 bases:

>100_bases
ATGGTGGTCTTCATGCTCACGGTTTTCGTGGCCTACGCCTACGTGTGGCGCCGCGGCGGCCTGACGTGGGACTGAGGGCC
GAGAGGGGATTGAGGTAAGC

Downstream 100 bases:

>100_bases
GCTCGCCCGACCAGGACCCCCGCGAGGCGATAGCCCAGGGCGACGACGAGGTGATCGACGTTCGTCGCGGCATGTTCGGG
GCCGCCGGCACCGGCGACAC

Product: NADH dehydrogenase subunit B

Products: NA

Alternate protein names: NADH dehydrogenase I subunit B; NDH-1 subunit B

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MGLEEQLPGGILLSTVEKVAGYVRKNSLWPATFGLACCAIEMMATAGPRFDIARFGMERFSATPRQADLMIVAGRVSQKM
APVLRQIYDQMAEPKWVLAMGVCASSGGMFNNYAIVQGVDHVVPVDIYLPGCPPRPEMLLYAILKLHEKIQQMPLGVNRE
TAIAEAEQAALSARPTIEMRGLLR

Sequences:

>Translated_184_residues
MGLEEQLPGGILLSTVEKVAGYVRKNSLWPATFGLACCAIEMMATAGPRFDIARFGMERFSATPRQADLMIVAGRVSQKM
APVLRQIYDQMAEPKWVLAMGVCASSGGMFNNYAIVQGVDHVVPVDIYLPGCPPRPEMLLYAILKLHEKIQQMPLGVNRE
TAIAEAEQAALSARPTIEMRGLLR
>Mature_183_residues
GLEEQLPGGILLSTVEKVAGYVRKNSLWPATFGLACCAIEMMATAGPRFDIARFGMERFSATPRQADLMIVAGRVSQKMA
PVLRQIYDQMAEPKWVLAMGVCASSGGMFNNYAIVQGVDHVVPVDIYLPGCPPRPEMLLYAILKLHEKIQQMPLGVNRET
AIAEAEQAALSARPTIEMRGLLR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family

Homologues:

Organism=Homo sapiens, GI187281616, Length=145, Percent_Identity=53.7931034482759, Blast_Score=179, Evalue=2e-45,
Organism=Escherichia coli, GI1788624, Length=175, Percent_Identity=47.4285714285714, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1789074, Length=112, Percent_Identity=41.0714285714286, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1788834, Length=135, Percent_Identity=34.0740740740741, Blast_Score=83, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17509685, Length=141, Percent_Identity=54.6099290780142, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24651058, Length=154, Percent_Identity=51.2987012987013, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI18859983, Length=142, Percent_Identity=52.8169014084507, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24642371, Length=142, Percent_Identity=52.8169014084507, Blast_Score=178, Evalue=2e-45,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NUOB_MYCA1 (A0QJU8)

Other databases:

- EMBL:   CP000479
- RefSeq:   YP_883186.1
- ProteinModelPortal:   A0QJU8
- SMR:   A0QJU8
- STRING:   A0QJU8
- EnsemblBacteria:   EBMYCT00000010537
- GeneID:   4527457
- GenomeReviews:   CP000479_GR
- KEGG:   mav:MAV_4034
- TIGR:   MAV_4034
- eggNOG:   COG0377
- GeneTree:   EBGT00050000016353
- HOGENOM:   HBG553221
- OMA:   GKPIGSN
- PhylomeDB:   A0QJU8
- ProtClustDB:   PRK06411
- BioCyc:   MAVI243243:MAV_4034-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01356
- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406
- PANTHER:   PTHR11995:SF2
- PANTHER:   PTHR11995
- TIGRFAMs:   TIGR01957

Pfam domain/function: PF01058 Oxidored_q6

EC number: =1.6.99.5

Molecular weight: Translated: 20149; Mature: 20018

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS01150 COMPLEX1_20K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLEEQLPGGILLSTVEKVAGYVRKNSLWPATFGLACCAIEMMATAGPRFDIARFGMERF
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SATPRQADLMIVAGRVSQKMAPVLRQIYDQMAEPKWVLAMGVCASSGGMFNNYAIVQGVD
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCHHHCCCC
HVVPVDIYLPGCPPRPEMLLYAILKLHEKIQQMPLGVNRETAIAEAEQAALSARPTIEMR
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHC
GLLR
CCCC
>Mature Secondary Structure 
GLEEQLPGGILLSTVEKVAGYVRKNSLWPATFGLACCAIEMMATAGPRFDIARFGMERF
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SATPRQADLMIVAGRVSQKMAPVLRQIYDQMAEPKWVLAMGVCASSGGMFNNYAIVQGVD
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCHHHCCCC
HVVPVDIYLPGCPPRPEMLLYAILKLHEKIQQMPLGVNRETAIAEAEQAALSARPTIEMR
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHC
GLLR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA