Click here to switch to the map view.

The map label for this gene is nuoC

Identifier: 41409301

GI number: 41409301

Start: 3552266

End: 3552973

Strand: Direct

Name: nuoC

Synonym: MAP3203

Alternate gene names: 41409301

Gene position: 3552266-3552973 (Clockwise)

Preceding gene: 41409300

Following gene: 41409302

Centisome position: 73.55

GC content: 67.51

Gene sequence:

>708_bases
ATGAGCTCGCCCGACCAGGACCCCCGCGAGGCGATAGCCCAGGGCGACGACGAGGTGATCGACGTTCGTCGCGGCATGTT
CGGGGCCGCCGGCACCGGCGACACGTCCGGCTACGGGCGGCTGGTGCGCACGGTCACCCTGCCCGGCAGCAGCCCGCGAC
CCTACGGCAGCTACTTCGACGACGTCGTCGACACGTTGACCGAGTCGTTGCAGAGCAACGGCATCGAATTCCACCAGGCG
ATCGAGAAGGTCGTGGTGTACCGCGACGAGCTCACCCTGCACGTCGACCGGGCCGCACTGCCGCACGTGGCCCAGCACCT
TCGCGACGACCCGCGGCTGCGTTTCGAGATGTGCCTGGGCGTTAGCGGCGTGCACTACCCGCACGAGACGGGTCGCGAAC
TGCACGCCGTCTATCCGCTGCAATCCATCACGCACAACCGCCGCGTCCGCCTGGAAGTGGCTGTGCCCGACGAGGATCCG
CACATCCCGTCGCTGTACCGGATCTATCCGACCACCGACTGGCACGAGCGCGAGACCTACGACTTCTTCGGCATCGTCTT
CGACGGGCACCCGTCGCTGACCCGCATCGAGATGCCGGACGACTGGCACGGGCATCCGCAGCGCAAGGACTACCCGCTCG
GCGGGATCCCGGTCGAATACAAAGGCGCACAGATACCCCCGCCCGACGAGCGGAGAGCGTACAACTGA

Upstream 100 bases:

>100_bases
AACAGATGCCGCTGGGCGTCAACCGGGAAACCGCCATCGCCGAAGCCGAGCAGGCGGCGCTGTCGGCCCGGCCCACCATC
GAGATGCGCGGACTGCTGCG

Downstream 100 bases:

>100_bases
TGAGCACCACCACCGAATCGACGCACGACGGCGCCGGCGAGACTCTCGTGGTCGCGGGCGGCCAGGACTGGGACAAGGTC
GTCGAGGCTGCCCGCAGCGC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSSPDQDPREAIAQGDDEVIDVRRGMFGAAGTGDTSGYGRLVRTVTLPGSSPRPYGSYFDDVVDTLTESLQSNGIEFHQA
IEKVVVYRDELTLHVDRAALPHVAQHLRDDPRLRFEMCLGVSGVHYPHETGRELHAVYPLQSITHNRRVRLEVAVPDEDP
HIPSLYRIYPTTDWHERETYDFFGIVFDGHPSLTRIEMPDDWHGHPQRKDYPLGGIPVEYKGAQIPPPDERRAYN

Sequences:

>Translated_235_residues
MSSPDQDPREAIAQGDDEVIDVRRGMFGAAGTGDTSGYGRLVRTVTLPGSSPRPYGSYFDDVVDTLTESLQSNGIEFHQA
IEKVVVYRDELTLHVDRAALPHVAQHLRDDPRLRFEMCLGVSGVHYPHETGRELHAVYPLQSITHNRRVRLEVAVPDEDP
HIPSLYRIYPTTDWHERETYDFFGIVFDGHPSLTRIEMPDDWHGHPQRKDYPLGGIPVEYKGAQIPPPDERRAYN
>Mature_234_residues
SSPDQDPREAIAQGDDEVIDVRRGMFGAAGTGDTSGYGRLVRTVTLPGSSPRPYGSYFDDVVDTLTESLQSNGIEFHQAI
EKVVVYRDELTLHVDRAALPHVAQHLRDDPRLRFEMCLGVSGVHYPHETGRELHAVYPLQSITHNRRVRLEVAVPDEDPH
IPSLYRIYPTTDWHERETYDFFGIVFDGHPSLTRIEMPDDWHGHPQRKDYPLGGIPVEYKGAQIPPPDERRAYN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=202, Percent_Identity=30.6930693069307, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI145693162, Length=124, Percent_Identity=41.1290322580645, Blast_Score=101, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71990788, Length=127, Percent_Identity=36.2204724409449, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32563621, Length=127, Percent_Identity=36.2204724409449, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24656494, Length=127, Percent_Identity=33.8582677165354, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 26694; Mature: 26563

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPDQDPREAIAQGDDEVIDVRRGMFGAAGTGDTSGYGRLVRTVTLPGSSPRPYGSYFD
CCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHH
DVVDTLTESLQSNGIEFHQAIEKVVVYRDELTLHVDRAALPHVAQHLRDDPRLRFEMCLG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECC
VSGVHYPHETGRELHAVYPLQSITHNRRVRLEVAVPDEDPHIPSLYRIYPTTDWHERETY
CCCCCCCCCCCCCEEEECCHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCE
DFFGIVFDGHPSLTRIEMPDDWHGHPQRKDYPLGGIPVEYKGAQIPPPDERRAYN
EEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSPDQDPREAIAQGDDEVIDVRRGMFGAAGTGDTSGYGRLVRTVTLPGSSPRPYGSYFD
CCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHH
DVVDTLTESLQSNGIEFHQAIEKVVVYRDELTLHVDRAALPHVAQHLRDDPRLRFEMCLG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECC
VSGVHYPHETGRELHAVYPLQSITHNRRVRLEVAVPDEDPHIPSLYRIYPTTDWHERETY
CCCCCCCCCCCCCEEEECCHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCE
DFFGIVFDGHPSLTRIEMPDDWHGHPQRKDYPLGGIPVEYKGAQIPPPDERRAYN
EEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA