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The map label for this gene is nuoA

Identifier: 41409299

GI number: 41409299

Start: 3551312

End: 3551689

Strand: Direct

Name: nuoA

Synonym: MAP3201

Alternate gene names: 41409299

Gene position: 3551312-3551689 (Clockwise)

Preceding gene: 41409298

Following gene: 41409300

Centisome position: 73.53

GC content: 63.23

Gene sequence:

>378_bases
TTGAACGTCTACATACCCATCCTGGTGCTGGGGGCGATCGCCACCGCCTTTGCCGTGGGCTCGGTGGTGATCGCGAGCCT
GGCCGGCCCGTCACGTTTCAACAAATCGAAGATGGCGGCCTACGAGTGCGGCATCGAGCCCACCGAAACCTCGGTGAGCG
GCCCGCGCGCCACGGCCGGACAGCGGTTTCCGGTGAAGTACTACCTGACCGCGATGCTGTTCATCGTCTTCGACATCGAA
ATCGTGTTCCTGTACCCGTGGGCGGTCAGCTACGACGCGCTGGGCACGTTTGCTCTGATCGAGATGGTGGTCTTCATGCT
CACGGTTTTCGTGGCCTACGCCTACGTGTGGCGCCGCGGCGGCCTGACGTGGGACTGA

Upstream 100 bases:

>100_bases
GTTGAAGATCACTGTGACGGTCCCGAAACCGGGTTCGTCACAGCAGCCCGGTTACCGCCTGGCCGCTGCAGGCGGCTCGC
ACGACGGATCATGGAGCGAG

Downstream 100 bases:

>100_bases
GGGCCGAGAGGGGATTGAGGTAAGCGTGGGTCTTGAGGAACAGCTGCCCGGCGGGATCCTGTTGTCGACGGTCGAGAAGG
TCGCCGGCTACGTCCGCAAG

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MNVYIPILVLGAIATAFAVGSVVIASLAGPSRFNKSKMAAYECGIEPTETSVSGPRATAGQRFPVKYYLTAMLFIVFDIE
IVFLYPWAVSYDALGTFALIEMVVFMLTVFVAYAYVWRRGGLTWD

Sequences:

>Translated_125_residues
MNVYIPILVLGAIATAFAVGSVVIASLAGPSRFNKSKMAAYECGIEPTETSVSGPRATAGQRFPVKYYLTAMLFIVFDIE
IVFLYPWAVSYDALGTFALIEMVVFMLTVFVAYAYVWRRGGLTWD
>Mature_125_residues
MNVYIPILVLGAIATAFAVGSVVIASLAGPSRFNKSKMAAYECGIEPTETSVSGPRATAGQRFPVKYYLTAMLFIVFDIE
IVFLYPWAVSYDALGTFALIEMVVFMLTVFVAYAYVWRRGGLTWD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13767; Mature: 13767

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVYIPILVLGAIATAFAVGSVVIASLAGPSRFNKSKMAAYECGIEPTETSVSGPRATAG
CCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
QRFPVKYYLTAMLFIVFDIEIVFLYPWAVSYDALGTFALIEMVVFMLTVFVAYAYVWRRG
CCCCHHHHHHHHHHHHHHHHHEEEECCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLTWD
CCCCC
>Mature Secondary Structure
MNVYIPILVLGAIATAFAVGSVVIASLAGPSRFNKSKMAAYECGIEPTETSVSGPRATAG
CCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
QRFPVKYYLTAMLFIVFDIEIVFLYPWAVSYDALGTFALIEMVVFMLTVFVAYAYVWRRG
CCCCHHHHHHHHHHHHHHHHHEEEECCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLTWD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]