Click here to switch to the map view.

The map label for this gene is kdgR [H]

Identifier: 41409125

GI number: 41409125

Start: 3367363

End: 3368064

Strand: Direct

Name: kdgR [H]

Synonym: MAP3027

Alternate gene names: 41409125

Gene position: 3367363-3368064 (Clockwise)

Preceding gene: 41409121

Following gene: 41409126

Centisome position: 69.72

GC content: 73.93

Gene sequence:

>702_bases
GTGAGACAGCATAGCGGCATCGGCGTCCTGGACAAAGCGGTGGGTGTGCTGCACACCGTCGCCCAATCACCCTGTGGGTT
GGCCGAACTCTGCGAGCGGACCGAGCTGCCCCGCGCCACCGCCTACCGGTTGGCGGCCGCGCTCGAGGTGCATCGCCTGC
TGGCGCGCGGCGACGACGGGCGCTGGCGGCTCGGCCCGGCGGTCACCGAACTGGCGGCACACGTCAACGATCCGCTGCTG
GCCGCCGGCAGCGCGGTGCTGCCGCTGTTGCGCGAGACCACCGGCGAGAGCGTGCAGCTGTACCGGCGCGAGGGCACCGA
CCGGGTGTGTGTGGCCGCACTGGAACCCGCTGCGGGCCTTAGGGATACGGTTCCGGTCGGGGCGCGGCTGCCGATGACCG
CGGGGTCGGGCGCCAAGGTGTTGCTCGCCCACAGCGACGCCGCCACCCAGAAGGCGGTGCTGGCAAACGCGAAATTCACC
GAGCGCACGCTGGCCGAGGTGAGGCGGCGCGGCTGGGCGCAAAGCGTGGCCGAACGCGAGCCGGGGGTGGCCAGCGTGTC
GGCGCCGGTGCGCGACAGCCGCGGTGCTGTCATCGCGGCCATCTCGGTGTCGGGCCCCATCGACCGGATCGGCCGGCGCC
CCGGGGCGCGCTGGGCCGCCGATCTGGTGTCCGCCGCCGAAGCGCTCACCCGCCGCCTCTAG

Upstream 100 bases:

>100_bases
GTGTCGATTCCCATCTCGAACTCGCCTCAATTCGCTTGGTCCGCGGCTCGCCGATCCGTCGGGCTGGTGATCTCATAATG
CGAGACGCTAGTATCTCGTT

Downstream 100 bases:

>100_bases
TTCTTTCTCGCGAGCAGACACAAAAGTCCCCTTTTCGGACGACTTTCGCGTGCTTTTGCGTCTGCTCGCGAGGGGACACA
GCGGACCTGACAGACTGACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRQHSGIGVLDKAVGVLHTVAQSPCGLAELCERTELPRATAYRLAAALEVHRLLARGDDGRWRLGPAVTELAAHVNDPLL
AAGSAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGLRDTVPVGARLPMTAGSGAKVLLAHSDAATQKAVLANAKFT
ERTLAEVRRRGWAQSVAEREPGVASVSAPVRDSRGAVIAAISVSGPIDRIGRRPGARWAADLVSAAEALTRRL

Sequences:

>Translated_233_residues
MRQHSGIGVLDKAVGVLHTVAQSPCGLAELCERTELPRATAYRLAAALEVHRLLARGDDGRWRLGPAVTELAAHVNDPLL
AAGSAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGLRDTVPVGARLPMTAGSGAKVLLAHSDAATQKAVLANAKFT
ERTLAEVRRRGWAQSVAEREPGVASVSAPVRDSRGAVIAAISVSGPIDRIGRRPGARWAADLVSAAEALTRRL
>Mature_233_residues
MRQHSGIGVLDKAVGVLHTVAQSPCGLAELCERTELPRATAYRLAAALEVHRLLARGDDGRWRLGPAVTELAAHVNDPLL
AAGSAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGLRDTVPVGARLPMTAGSGAKVLLAHSDAATQKAVLANAKFT
ERTLAEVRRRGWAQSVAEREPGVASVSAPVRDSRGAVIAAISVSGPIDRIGRRPGARWAADLVSAAEALTRRL

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=249, Percent_Identity=25.3012048192771, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786715, Length=229, Percent_Identity=26.2008733624454, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082359, Length=241, Percent_Identity=25.7261410788382, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788581, Length=249, Percent_Identity=25.3012048192771, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786468, Length=245, Percent_Identity=25.3061224489796, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 24504; Mature: 24504

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQHSGIGVLDKAVGVLHTVAQSPCGLAELCERTELPRATAYRLAAALEVHRLLARGDDG
CCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
RWRLGPAVTELAAHVNDPLLAAGSAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGL
CEECCHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCCEEHHHHCCCCEEEEEECCCCCCC
RDTVPVGARLPMTAGSGAKVLLAHSDAATQKAVLANAKFTERTLAEVRRRGWAQSVAERE
CCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
PGVASVSAPVRDSRGAVIAAISVSGPIDRIGRRPGARWAADLVSAAEALTRRL
CCCEECCCCCCCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRQHSGIGVLDKAVGVLHTVAQSPCGLAELCERTELPRATAYRLAAALEVHRLLARGDDG
CCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
RWRLGPAVTELAAHVNDPLLAAGSAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGL
CEECCHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCCEEHHHHCCCCEEEEEECCCCCCC
RDTVPVGARLPMTAGSGAKVLLAHSDAATQKAVLANAKFTERTLAEVRRRGWAQSVAERE
CCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
PGVASVSAPVRDSRGAVIAAISVSGPIDRIGRRPGARWAADLVSAAEALTRRL
CCCEECCCCCCCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]