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The map label for this gene is ftsK

Identifier: 41408957

GI number: 41408957

Start: 3185327

End: 3188014

Strand: Reverse

Name: ftsK

Synonym: MAP2859c

Alternate gene names: 41408957

Gene position: 3188014-3185327 (Counterclockwise)

Preceding gene: 41408961

Following gene: 41408955

Centisome position: 66.01

GC content: 71.06

Gene sequence:

>2688_bases
TTGTGGCCTCCTGGGCGCTCCGGGGGTGGGGTGACGAGCACGACTTCTCGCACCGGATGTCACCCTACTCACGCGAATTC
GGGGCCCATCCCGCAGCTGCCGCAAAGCCTGGTCGTTACCAGTGTGGCGGGTGGTGTAGATGATGCCGTTGCGACTACCC
TTGCCGTCATGCCCAGTAAGACCGCCGCCCGCTCCGGAAACCGAACGAGCAGGTCAAAGGCCACTTCGCGGTCCAACGGG
TCGCGCGGCGCGCGACCGGCGGCGCCCCGCCGCAAGCCCGGCAGGCCCACCCGGCGGCGGCAGCACCCGCCGCTAGTCGC
CGCGGGCCTGACCTGCGGCCGCGCCCTGCGCGCCGGCTGGATGCTGGCCGCCCGGGGCACCGGCGGCGCGGCCCGGTCGA
TCGGGCGGGCCCGCGACATCGACCCCGGGCACCGCCGCGACGGCATCGCGCTGCTGCTGCTGGGCTTCTCGGTGGTGGTC
GCCGCCAGCTCGTGGTTCCACGCCGCCGGGCCGGTCGGGGCCTGGGTGGACACCGCGCTGCGGACGTTCATCGGCGCGGG
CGTGCTGGCGCTGCCGGTCGTCACGGCCGCGGTGGCGGTGACGCTGATGCGCACCGAGCCCGATCCCGACGTGCGGCCCA
GGCTGATCCTGGGCGCCGGGCTGATCGCCCTGTCGGTGCTGGGCCTGCGCCACCTGTGGTCGGGATCGCCGGGCGACCCC
GACGCGCGCCGCCGCGCGGCCGGATTCATCGGCTTCGCCATCGGCGGCCCGCTCTCCGACGGGCTGACGCCCTGGATCGC
GGCGCCGCTGCTGTTCATCGGCTTCATGTTCGGGCTGCTGCTGTTGACCGGCACCACCATCCGCGAGCTGCCCGTGGTGA
TGCGCAACCTGTTCCACACCCGGTTCGTCGAGGACTACACCGACGAGGACTACACCGACGAGGACTACACCGACGGGGAC
TACGGCGACGAGCCCTACGACTACGCCGGCGAATTCGACGACGCGGCCGCGCAACCGGAGCCGGAACCGGCGGCGTGGGC
GCCCGACGACGACGCCCAGGCCGCGCTGCAGGACGACATCCCCACCGTGCCCGAGCCCGCCGTCAAAACCGGGCGCGGCC
GCAAGCGGGGACGCGCGGCCGACAACTCCGACACCATCGAGCTGGACCGGGTGGTCGAGGGACCCTACGTGCTGCCGTCG
CTGAGCCTGCTGGTGGCCGGGGACCCGCCGAAGAAGCGCAGCGCCGCGAACAACGTCATGGCCGACGCCATCACCGAGGT
GCTCAACCAGTTCAAGGTGGACGCCGCCGTCACCGGCTGCACCCGCGGGCCGACCGTGACCCGCTACGAGGTGGAGCTGG
GGCCCGGGGTGAAGGTGGAGAAGATCACCGCCCTGCAGAAGAACATCGCGTACGCGGTGGCCACCGAGAGCGTGCGGATG
CTGGCGCCCATCCCCGGCAAGTCGGCCGTCGGCATCGAGGTGCCCAACACCGACCGCGAGATGGTGCGGCTGGCCGACGT
GCTGACCGCCCCGTCCACCCGTCGCGACCACCACCCGCTGGTGATCGGCCTGGGCAAGGACATCGAGGGCGACTTCATTT
CGGCGAACCTGGCCAAGATGCCGCACCTGCTGGTGGCCGGCTCCACCGGCTCCGGCAAGTCCAGCTTCGTCAACTCGATG
CTGATCTCGCTGCTGGCCCGGGCCACCCCGGAAGAGGTCAGGATGATCCTGATCGACCCGAAGATGGTGGAACTGACGCC
CTACGAAGGCATTCCGCATCTGATCACCCCGATCATCACCCAGCCCAAGAAGGCCGCCGCTGCGCTGGCCTGGCTGGTCG
AGGAGATGGAGCAGCGCTACCAGGACATGCAGGCCTCCCGGGTGCGCCACATCGACGACTTCAACGCCAAGGTGCGCTCC
GGTGAGATCACCGCGCCGCTGGGCAGCCAGCGCGAATACCGGCCCTACCCGTACGTCGTCGCGATCGTCGACGAGCTGGC
CGACCTGATGATGACCGCGCCGCGCGACGTCGAGGACGCCATCGTGCGGATCACCCAGAAGGCCCGCGCCGCGGGCATTC
ACCTGGTGCTGGCCACCCAGCGCCCGTCCGTCGACGTCGTCACCGGCCTGATCAAGACCAACGTGCCGTCCCGGCTGGCG
TTCGCGACGTCGTCGCTCACCGACTCCCGGGTGATCCTGGACCAGGCCGGCGCGGAGAAGCTGATCGGCATGGGCGACGG
CCTGTTCCTGCCGATGGGCGCGTCCAAGCCGATCCGGTTGCAGGGCGCCTTCATCACCGACGAGGAGATCCAGGCCGTCG
TCGCCGCCTGCAAGGACCAGGCCGAACCCGAGTACACCGAGGGCGTCACCGCCGTCAAAACCAGCAGCGAACGCGCCGAC
GTCGACCCCGACATCGGCGACGACATGGACGTGTTCCTGCAGGCCGTCGAGCTGGTGGTGTCCAGCCAGTTCGGCTCCAC
CTCGATGCTGCAGCGCAAGCTGCGGGTCGGGTTCGCCAAGGCCGGCCGGCTGATGGACCTGATGGAGACCCGCGGCATCG
TCGGGCCCTCCGAGGGATCCAAGGCGCGCGAGGTGCTGGTCAAGCCCGATGAGCTGGCCGGCACGCTGGCGCTGATCCGC
GGCTCCGGGGCCGGATCGGCCGACGCCGACGGCGGCGATCCCGACTAG

Upstream 100 bases:

>100_bases
TCGTCGTGCACCTCTTCGACCGCACGAGTCAGGATGTCGCGGACGGTGTCGACCGATTCCGGTTTGACGGTCATGGTGGC
GACGACGACGACGGGCATGC

Downstream 100 bases:

>100_bases
CGCGGTTTAGCGCCGAACGTCACGCCAGCGTGACGTTCCGGCGCCAGCGTCACGCCAGCGTGACTGTCGCGCGGCGCGAG
CGCGAGCGTTACAGCACCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 895; Mature: 895

Protein sequence:

>895_residues
MWPPGRSGGGVTSTTSRTGCHPTHANSGPIPQLPQSLVVTSVAGGVDDAVATTLAVMPSKTAARSGNRTSRSKATSRSNG
SRGARPAAPRRKPGRPTRRRQHPPLVAAGLTCGRALRAGWMLAARGTGGAARSIGRARDIDPGHRRDGIALLLLGFSVVV
AASSWFHAAGPVGAWVDTALRTFIGAGVLALPVVTAAVAVTLMRTEPDPDVRPRLILGAGLIALSVLGLRHLWSGSPGDP
DARRRAAGFIGFAIGGPLSDGLTPWIAAPLLFIGFMFGLLLLTGTTIRELPVVMRNLFHTRFVEDYTDEDYTDEDYTDGD
YGDEPYDYAGEFDDAAAQPEPEPAAWAPDDDAQAALQDDIPTVPEPAVKTGRGRKRGRAADNSDTIELDRVVEGPYVLPS
LSLLVAGDPPKKRSAANNVMADAITEVLNQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRM
LAPIPGKSAVGIEVPNTDREMVRLADVLTAPSTRRDHHPLVIGLGKDIEGDFISANLAKMPHLLVAGSTGSGKSSFVNSM
LISLLARATPEEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNAKVRS
GEITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLA
FATSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPIRLQGAFITDEEIQAVVAACKDQAEPEYTEGVTAVKTSSERAD
VDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIR
GSGAGSADADGGDPD

Sequences:

>Translated_895_residues
MWPPGRSGGGVTSTTSRTGCHPTHANSGPIPQLPQSLVVTSVAGGVDDAVATTLAVMPSKTAARSGNRTSRSKATSRSNG
SRGARPAAPRRKPGRPTRRRQHPPLVAAGLTCGRALRAGWMLAARGTGGAARSIGRARDIDPGHRRDGIALLLLGFSVVV
AASSWFHAAGPVGAWVDTALRTFIGAGVLALPVVTAAVAVTLMRTEPDPDVRPRLILGAGLIALSVLGLRHLWSGSPGDP
DARRRAAGFIGFAIGGPLSDGLTPWIAAPLLFIGFMFGLLLLTGTTIRELPVVMRNLFHTRFVEDYTDEDYTDEDYTDGD
YGDEPYDYAGEFDDAAAQPEPEPAAWAPDDDAQAALQDDIPTVPEPAVKTGRGRKRGRAADNSDTIELDRVVEGPYVLPS
LSLLVAGDPPKKRSAANNVMADAITEVLNQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRM
LAPIPGKSAVGIEVPNTDREMVRLADVLTAPSTRRDHHPLVIGLGKDIEGDFISANLAKMPHLLVAGSTGSGKSSFVNSM
LISLLARATPEEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNAKVRS
GEITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLA
FATSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPIRLQGAFITDEEIQAVVAACKDQAEPEYTEGVTAVKTSSERAD
VDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIR
GSGAGSADADGGDPD
>Mature_895_residues
MWPPGRSGGGVTSTTSRTGCHPTHANSGPIPQLPQSLVVTSVAGGVDDAVATTLAVMPSKTAARSGNRTSRSKATSRSNG
SRGARPAAPRRKPGRPTRRRQHPPLVAAGLTCGRALRAGWMLAARGTGGAARSIGRARDIDPGHRRDGIALLLLGFSVVV
AASSWFHAAGPVGAWVDTALRTFIGAGVLALPVVTAAVAVTLMRTEPDPDVRPRLILGAGLIALSVLGLRHLWSGSPGDP
DARRRAAGFIGFAIGGPLSDGLTPWIAAPLLFIGFMFGLLLLTGTTIRELPVVMRNLFHTRFVEDYTDEDYTDEDYTDGD
YGDEPYDYAGEFDDAAAQPEPEPAAWAPDDDAQAALQDDIPTVPEPAVKTGRGRKRGRAADNSDTIELDRVVEGPYVLPS
LSLLVAGDPPKKRSAANNVMADAITEVLNQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRM
LAPIPGKSAVGIEVPNTDREMVRLADVLTAPSTRRDHHPLVIGLGKDIEGDFISANLAKMPHLLVAGSTGSGKSSFVNSM
LISLLARATPEEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNAKVRS
GEITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLA
FATSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPIRLQGAFITDEEIQAVVAACKDQAEPEYTEGVTAVKTSSERAD
VDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIR
GSGAGSADADGGDPD

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=490, Percent_Identity=46.3265306122449, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 94993; Mature: 94993

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWPPGRSGGGVTSTTSRTGCHPTHANSGPIPQLPQSLVVTSVAGGVDDAVATTLAVMPSK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCH
TAARSGNRTSRSKATSRSNGSRGARPAAPRRKPGRPTRRRQHPPLVAAGLTCGRALRAGW
HHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCE
MLAARGTGGAARSIGRARDIDPGHRRDGIALLLLGFSVVVAASSWFHAAGPVGAWVDTAL
EEEECCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RTFIGAGVLALPVVTAAVAVTLMRTEPDPDVRPRLILGAGLIALSVLGLRHLWSGSPGDP
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCH
DARRRAAGFIGFAIGGPLSDGLTPWIAAPLLFIGFMFGLLLLTGTTIRELPVVMRNLFHT
HHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RFVEDYTDEDYTDEDYTDGDYGDEPYDYAGEFDDAAAQPEPEPAAWAPDDDAQAALQDDI
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC
PTVPEPAVKTGRGRKRGRAADNSDTIELDRVVEGPYVLPSLSLLVAGDPPKKRSAANNVM
CCCCCCHHHCCCCCCCCCCCCCCCCEEEEHHCCCCEECCCCEEEEECCCCHHHHHHHHHH
ADAITEVLNQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRM
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEECCCEEE
LAPIPGKSAVGIEVPNTDREMVRLADVLTAPSTRRDHHPLVIGLGKDIEGDFISANLAKM
EECCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEECCHHHC
PHLLVAGSTGSGKSSFVNSMLISLLARATPEEVRMILIDPKMVELTPYEGIPHLITPIIT
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCCCHHHHHHHHC
QPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNAKVRSGEITAPLGSQREYRPYPYVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEECCCCCCCCCCCCCHHH
AIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCHHHH
FATSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPIRLQGAFITDEEIQAVVAACKDQ
HHHCCCCCCCHHHHHCCCHHHHCCCCCEEEECCCCCCEEEEEEEECHHHHHHHHHHHHHC
AEPEYTEGVTAVKTSSERADVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAK
CCCCHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIRGSGAGSADADGGDPD
HHHHHHHHHHCCCCCCCCCCHHHHEECCCHHHHCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MWPPGRSGGGVTSTTSRTGCHPTHANSGPIPQLPQSLVVTSVAGGVDDAVATTLAVMPSK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCH
TAARSGNRTSRSKATSRSNGSRGARPAAPRRKPGRPTRRRQHPPLVAAGLTCGRALRAGW
HHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCE
MLAARGTGGAARSIGRARDIDPGHRRDGIALLLLGFSVVVAASSWFHAAGPVGAWVDTAL
EEEECCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RTFIGAGVLALPVVTAAVAVTLMRTEPDPDVRPRLILGAGLIALSVLGLRHLWSGSPGDP
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCH
DARRRAAGFIGFAIGGPLSDGLTPWIAAPLLFIGFMFGLLLLTGTTIRELPVVMRNLFHT
HHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RFVEDYTDEDYTDEDYTDGDYGDEPYDYAGEFDDAAAQPEPEPAAWAPDDDAQAALQDDI
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC
PTVPEPAVKTGRGRKRGRAADNSDTIELDRVVEGPYVLPSLSLLVAGDPPKKRSAANNVM
CCCCCCHHHCCCCCCCCCCCCCCCCEEEEHHCCCCEECCCCEEEEECCCCHHHHHHHHHH
ADAITEVLNQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRM
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEECCCEEE
LAPIPGKSAVGIEVPNTDREMVRLADVLTAPSTRRDHHPLVIGLGKDIEGDFISANLAKM
EECCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEECCHHHC
PHLLVAGSTGSGKSSFVNSMLISLLARATPEEVRMILIDPKMVELTPYEGIPHLITPIIT
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCCCHHHHHHHHC
QPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNAKVRSGEITAPLGSQREYRPYPYVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEECCCCCCCCCCCCCHHH
AIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCHHHH
FATSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPIRLQGAFITDEEIQAVVAACKDQ
HHHCCCCCCCHHHHHCCCHHHHCCCCCEEEECCCCCCEEEEEEEECHHHHHHHHHHHHHC
AEPEYTEGVTAVKTSSERADVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAK
CCCCHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIRGSGAGSADADGGDPD
HHHHHHHHHHCCCCCCCCCCHHHHEECCCHHHHCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]