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The map label for this gene is pgsA3

Identifier: 41408955

GI number: 41408955

Start: 3184058

End: 3184657

Strand: Reverse

Name: pgsA3

Synonym: MAP2857c

Alternate gene names: 41408955

Gene position: 3184657-3184058 (Counterclockwise)

Preceding gene: 41408957

Following gene: 41408954

Centisome position: 65.94

GC content: 68.67

Gene sequence:

>600_bases
GTGCCGGGGCAGCCGCAGACGGGTCCGATGGTAGGGCGGGCAAACATCGCCAACCTGGCCAACACGTTGACCCTGCTGCG
GCTGGTGTTGGTGCCGGTCTTTCTGCTCGCCCTGTTCGCCGGTGACGGCCACGAGACCGGCTTCCGCATCCTGGCTTTCC
TGATCTTCGCGTTCGCCTGCATCACCGATCGGTTGGACGGGCTGCTGGCCCGCAACTACGGGATGGCCACCGAATTCGGC
GCGTTCGTCGACCCGATCGCGGACAAGACGCTGGTCGGGTCGGCGCTGATCGGGCTGTCCATGCTCGGCGAGCTGCCGTG
GTGGATCACCGTGCTGATCCTGGCCCGCGAATTCGGGGTCACCGTGCTGCGGTTGGCGGTCATCCGCCGGGGCGTGATCC
CGGCCAGCTGGGGCGGCAAGCTCAAGACGGTGGTGCAGGTGTTCGCCATCGGTTTGTTCGTGCTGCCGTGGGCGGGCACG
CCCGGGCCGTTCCGGGTGGGCGCGGCCGTGGTGATGGGCGCGGCCATCGTGCTCACGGTGATCACCGGGATCGACTACGT
GGTCTCGACGGTGCGCGAAGTGCGCCGGACCGCTGCCTGA

Upstream 100 bases:

>100_bases
GCGCGTCGAACCAGCGGCCGGTAGCGCTGCGGACTTTCGGTCACGGCTAACAGTATCGGCATCACGGACGGCTGCGCTGG
TCAACCGTTATTCTGTTGCG

Downstream 100 bases:

>100_bases
TTCGGGGTGATTCGGCATCCCCGAACGGGAACCACCGCGGCCCCGCCGGCGTTCACCTAATTGAGCACCTGCCGGAGGCG
AGTGAAGAGGCGTGCCGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MPGQPQTGPMVGRANIANLANTLTLLRLVLVPVFLLALFAGDGHETGFRILAFLIFAFACITDRLDGLLARNYGMATEFG
AFVDPIADKTLVGSALIGLSMLGELPWWITVLILAREFGVTVLRLAVIRRGVIPASWGGKLKTVVQVFAIGLFVLPWAGT
PGPFRVGAAVVMGAAIVLTVITGIDYVVSTVREVRRTAA

Sequences:

>Translated_199_residues
MPGQPQTGPMVGRANIANLANTLTLLRLVLVPVFLLALFAGDGHETGFRILAFLIFAFACITDRLDGLLARNYGMATEFG
AFVDPIADKTLVGSALIGLSMLGELPWWITVLILAREFGVTVLRLAVIRRGVIPASWGGKLKTVVQVFAIGLFVLPWAGT
PGPFRVGAAVVMGAAIVLTVITGIDYVVSTVREVRRTAA
>Mature_198_residues
PGQPQTGPMVGRANIANLANTLTLLRLVLVPVFLLALFAGDGHETGFRILAFLIFAFACITDRLDGLLARNYGMATEFGA
FVDPIADKTLVGSALIGLSMLGELPWWITVLILAREFGVTVLRLAVIRRGVIPASWGGKLKTVVQVFAIGLFVLPWAGTP
GPFRVGAAVVMGAAIVLTVITGIDYVVSTVREVRRTAA

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=140, Percent_Identity=37.1428571428571, Blast_Score=85, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24650130, Length=106, Percent_Identity=39.622641509434, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650126, Length=106, Percent_Identity=39.622641509434, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650128, Length=106, Percent_Identity=39.622641509434, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21160; Mature: 21028

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGQPQTGPMVGRANIANLANTLTLLRLVLVPVFLLALFAGDGHETGFRILAFLIFAFAC
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ITDRLDGLLARNYGMATEFGAFVDPIADKTLVGSALIGLSMLGELPWWITVLILAREFGV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TVLRLAVIRRGVIPASWGGKLKTVVQVFAIGLFVLPWAGTPGPFRVGAAVVMGAAIVLTV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ITGIDYVVSTVREVRRTAA
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PGQPQTGPMVGRANIANLANTLTLLRLVLVPVFLLALFAGDGHETGFRILAFLIFAFAC
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ITDRLDGLLARNYGMATEFGAFVDPIADKTLVGSALIGLSMLGELPWWITVLILAREFGV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TVLRLAVIRRGVIPASWGGKLKTVVQVFAIGLFVLPWAGTPGPFRVGAAVVMGAAIVLTV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ITGIDYVVSTVREVRRTAA
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]