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The map label for this gene is srpA [H]

Identifier: 41408842

GI number: 41408842

Start: 3075342

End: 3076283

Strand: Reverse

Name: srpA [H]

Synonym: MAP2744c

Alternate gene names: 41408842

Gene position: 3076283-3075342 (Counterclockwise)

Preceding gene: 41408843

Following gene: 41408841

Centisome position: 63.69

GC content: 70.91

Gene sequence:

>942_bases
ATGAGCGGTGGATTAACTCCCGACCAGGCGATCGACGCGATCCGGGGGACCGGGGGAGCCCAGCCCGGCTGCCGCGCACT
GCACGCCAAGGGCACGCTGTACCGCGGCACGTTCACCGCCACCCGGGATGCGGTGATGCTTTCGGCCGCACCGCATCTCG
ACGGCTCGACGGTCCCGGCGCTGATCCGCTTCTCCAACGGATCGGGCAACCCGAAGCAACGCGACGGCGCGCCCGGGGTG
CGCGGGATGGCGGTCAAGTTCACCCTGCCGGACGGCTCCACCACCGACGTCTCGGCGCAGACCGCGCGGCTGTTAGTCTC
CAGCACCCCGGAGGGGTTTATCGATCTGCTCAAGGCGATGCGGCCCGGCCTGACCACGCCGCTGCGGTTGGCCACCCACC
TGCTCACCCATCCGCGGCTGCTCGGGGCGCTGCCCCTGCTGCGGGAGGCCAACCGGATCCCGGCCAGCTACGCCACCACC
GAGTACCACGGCCTGCACGCCTTCCGCTGGATCGCCGCCGACGGCAGCGCGAGATTCGTTCGCTATCACCTGGTTCCGAC
CGCGGCCGAGGAATACCTGTCGGCCTCCGACGCCCGCGGCAAGGACCCGGACTTTCTCACCGACGAGCTGGCGGCGCGAC
TGCAGGACGGGCCGGTGCGGTTCGACTTCCGGGTGCAGATCGCCGGGCCCACGGACTCGACGGTGGACCCCTCGTCGGCC
TGGCAGAGCACGCAGATCGTCACCGTCGGCACCGTGACGATCACCGGCCCCGACACCGAACGCGAGCACGGCGGCGACAT
CGTCGTCTTCGACCCGATGCGCGTCACCGACGGCATCGAGCCCTCCGACGATCCGGTGCTGCGGTTCCGGACCCTGGTGT
ACTCGGCGTCGGTCAAGTTGCGGACCGGGGTGGATCGCGGCGCGCAAGCCCCGCCGGTGTGA

Upstream 100 bases:

>100_bases
TCGACGGCGGCTACACCGCCGGCCGCGATCACGGCGTGGTGGAACTGTTCGGCTTTCCCAGCTGATACCAATTGGATTCA
ATTACCACTAAGATCCGTCC

Downstream 100 bases:

>100_bases
CCTTGGCCCCTTGGTCTGCGCCGAAATCGGCGGCAGGCTAAGGTTTTTCTCCGGTGTCGCCATTTCAGATGTTCGTCATA
TGCCTGGCCGGGCTGGCCGC

Product: hypothetical protein

Products: H2O; O2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSGGLTPDQAIDAIRGTGGAQPGCRALHAKGTLYRGTFTATRDAVMLSAAPHLDGSTVPALIRFSNGSGNPKQRDGAPGV
RGMAVKFTLPDGSTTDVSAQTARLLVSSTPEGFIDLLKAMRPGLTTPLRLATHLLTHPRLLGALPLLREANRIPASYATT
EYHGLHAFRWIAADGSARFVRYHLVPTAAEEYLSASDARGKDPDFLTDELAARLQDGPVRFDFRVQIAGPTDSTVDPSSA
WQSTQIVTVGTVTITGPDTEREHGGDIVVFDPMRVTDGIEPSDDPVLRFRTLVYSASVKLRTGVDRGAQAPPV

Sequences:

>Translated_313_residues
MSGGLTPDQAIDAIRGTGGAQPGCRALHAKGTLYRGTFTATRDAVMLSAAPHLDGSTVPALIRFSNGSGNPKQRDGAPGV
RGMAVKFTLPDGSTTDVSAQTARLLVSSTPEGFIDLLKAMRPGLTTPLRLATHLLTHPRLLGALPLLREANRIPASYATT
EYHGLHAFRWIAADGSARFVRYHLVPTAAEEYLSASDARGKDPDFLTDELAARLQDGPVRFDFRVQIAGPTDSTVDPSSA
WQSTQIVTVGTVTITGPDTEREHGGDIVVFDPMRVTDGIEPSDDPVLRFRTLVYSASVKLRTGVDRGAQAPPV
>Mature_312_residues
SGGLTPDQAIDAIRGTGGAQPGCRALHAKGTLYRGTFTATRDAVMLSAAPHLDGSTVPALIRFSNGSGNPKQRDGAPGVR
GMAVKFTLPDGSTTDVSAQTARLLVSSTPEGFIDLLKAMRPGLTTPLRLATHLLTHPRLLGALPLLREANRIPASYATTE
YHGLHAFRWIAADGSARFVRYHLVPTAAEEYLSASDARGKDPDFLTDELAARLQDGPVRFDFRVQIAGPTDSTVDPSSAW
QSTQIVTVGTVTITGPDTEREHGGDIVVFDPMRVTDGIEPSDDPVLRFRTLVYSASVKLRTGVDRGAQAPPV

Specific function: Decomposes Hydrogen Peroxide Into Water And Oxygen; Serves To Protect Cells From The Toxic Effects Of Hydrogen Peroxide. [C]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=297, Percent_Identity=24.2424242424242, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI48994891, Length=305, Percent_Identity=25.9016393442623, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71998444, Length=303, Percent_Identity=24.7524752475248, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19920968, Length=299, Percent_Identity=24.7491638795987, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17981717, Length=297, Percent_Identity=23.5690235690236, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020835
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase [H]

EC number: 1.11.1.6 [C]

Molecular weight: Translated: 33321; Mature: 33190

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGLTPDQAIDAIRGTGGAQPGCRALHAKGTLYRGTFTATRDAVMLSAAPHLDGSTVPA
CCCCCCHHHHHHHHHCCCCCCCCCEEEECCCEEEECEECCCCCEEEEEECCCCCCCCCEE
LIRFSNGSGNPKQRDGAPGVRGMAVKFTLPDGSTTDVSAQTARLLVSSTPEGFIDLLKAM
EEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHEEEEECCCHHHHHHHHHH
RPGLTTPLRLATHLLTHPRLLGALPLLREANRIPASYATTEYHGLHAFRWIAADGSARFV
CCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCEEE
RYHLVPTAAEEYLSASDARGKDPDFLTDELAARLQDGPVRFDFRVQIAGPTDSTVDPSSA
EEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCC
WQSTQIVTVGTVTITGPDTEREHGGDIVVFDPMRVTDGIEPSDDPVLRFRTLVYSASVKL
CCCEEEEEEEEEEEECCCCCHHCCCCEEEECCHHHCCCCCCCCCHHHHHEEHHHCCCEEE
RTGVDRGAQAPPV
ECCCCCCCCCCCC
>Mature Secondary Structure 
SGGLTPDQAIDAIRGTGGAQPGCRALHAKGTLYRGTFTATRDAVMLSAAPHLDGSTVPA
CCCCCHHHHHHHHHCCCCCCCCCEEEECCCEEEECEECCCCCEEEEEECCCCCCCCCEE
LIRFSNGSGNPKQRDGAPGVRGMAVKFTLPDGSTTDVSAQTARLLVSSTPEGFIDLLKAM
EEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHEEEEECCCHHHHHHHHHH
RPGLTTPLRLATHLLTHPRLLGALPLLREANRIPASYATTEYHGLHAFRWIAADGSARFV
CCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCEEE
RYHLVPTAAEEYLSASDARGKDPDFLTDELAARLQDGPVRFDFRVQIAGPTDSTVDPSSA
EEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCC
WQSTQIVTVGTVTITGPDTEREHGGDIVVFDPMRVTDGIEPSDDPVLRFRTLVYSASVKL
CCCEEEEEEEEEEEECCCCCHHCCCCEEEECCHHHCCCCCCCCCHHHHHEEHHHCCCEEE
RTGVDRGAQAPPV
ECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Heme Group. [C]

Metal ions: NA

Kcat value (1/min): 980000 [C]

Specific activity: NA

Km value (mM): 18.2 {H2O2}} 10 {H2O2}} 3.7 {H2O2}} [C]

Substrates: Hydrogen peroxide [C]

Specific reaction: (2) Hydrogen peroxide --> (2) H2O + O2 [C]

General reaction: Redox reaction [C]

Inhibitor: 3-Amino-1-H-1, 2, 4-triazolecoli, Rhodopseudomonascapsulata; Dianisidine; H2O2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7536734 [H]