| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is bacC [H]
Identifier: 41408843
GI number: 41408843
Start: 3076319
End: 3077119
Strand: Reverse
Name: bacC [H]
Synonym: MAP2745c
Alternate gene names: 41408843
Gene position: 3077119-3076319 (Counterclockwise)
Preceding gene: 41408846
Following gene: 41408842
Centisome position: 63.71
GC content: 72.66
Gene sequence:
>801_bases ATGACGGGCATGGTGAACCCCGACCGTGCCCGTTCCCGCACCTTCGTCGTGACCGGCGCCGCCTCCGGCATCGGCCTGGC CACCGCGCGGCGGCTGCTGGCCGAGGGCGGCACCGTGGTCGGCGCCGACCTGGCCGACCCGCCCGGCGGCCTGGGCCCCC GGTTCACCTTCGTGCCCGCCGACGTGACCGACGAATCCGCCGTCGCCGCGGTGCTGGCCGCTGTGCCGGGCCGCCTCGAC GGCGTCTTCCACGCCGCCGGTGTCGCCGGGGGAGGCCCGGTGCACCTGCTGGACCGAGCCGAATGGGACCGGGTGATCGG GGTCAACCTCACCGGCACCTTCCTGGTGGCCAAGGCGGCCCTGGCGCGGATGATCGACCAATCCCGCGTCGACGGCGAGC GCGGTTCGCTCGTCACGGTCGCCAGCGTCGAGGGCCTGGAGGGCACCGCCGGGGGCAGCTCCTACAACGCGGCCAAGGGC GGTGTCGTGCTGCTGACCAAGAACATCGCGCTCGACTACGGGCCCAGCGGGATCCGCGCCAACGTCATCTGCCCCGGCTT CATCGAAACGCCCATGGCGCACAACGTGTTCAGCATTCCCGGTATGGAGGCGCCGCTGGCCTCGATCACCAGGGAGCACG CCCTGCAGCGGCTGGGGCGGCCCGAAGAGATCGCCGCGATGGCCGCCTTCCTGCTGTCCACCGACGCCTCGTTCGTCAGC GGCCAGGCCATCGCCGTCGACGGCGGCTACACCGCCGGCCGCGATCACGGCGTGGTGGAACTGTTCGGCTTTCCCAGCTG A
Upstream 100 bases:
>100_bases TCGATAGGGCGCCGACGCTGGTCTGGTAAACCTCAGTGCGCCAACGTATTTCAGCAGAAACCAGCCATCGGCAACCCCGG GACCGGCGCGGTGTGCCACC
Downstream 100 bases:
>100_bases TACCAATTGGATTCAATTACCACTAAGATCCGTCCATGAGCGGTGGATTAACTCCCGACCAGGCGATCGACGCGATCCGG GGGACCGGGGGAGCCCAGCC
Product: hypothetical protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 266; Mature: 265
Protein sequence:
>266_residues MTGMVNPDRARSRTFVVTGAASGIGLATARRLLAEGGTVVGADLADPPGGLGPRFTFVPADVTDESAVAAVLAAVPGRLD GVFHAAGVAGGGPVHLLDRAEWDRVIGVNLTGTFLVAKAALARMIDQSRVDGERGSLVTVASVEGLEGTAGGSSYNAAKG GVVLLTKNIALDYGPSGIRANVICPGFIETPMAHNVFSIPGMEAPLASITREHALQRLGRPEEIAAMAAFLLSTDASFVS GQAIAVDGGYTAGRDHGVVELFGFPS
Sequences:
>Translated_266_residues MTGMVNPDRARSRTFVVTGAASGIGLATARRLLAEGGTVVGADLADPPGGLGPRFTFVPADVTDESAVAAVLAAVPGRLD GVFHAAGVAGGGPVHLLDRAEWDRVIGVNLTGTFLVAKAALARMIDQSRVDGERGSLVTVASVEGLEGTAGGSSYNAAKG GVVLLTKNIALDYGPSGIRANVICPGFIETPMAHNVFSIPGMEAPLASITREHALQRLGRPEEIAAMAAFLLSTDASFVS GQAIAVDGGYTAGRDHGVVELFGFPS >Mature_265_residues TGMVNPDRARSRTFVVTGAASGIGLATARRLLAEGGTVVGADLADPPGGLGPRFTFVPADVTDESAVAAVLAAVPGRLDG VFHAAGVAGGGPVHLLDRAEWDRVIGVNLTGTFLVAKAALARMIDQSRVDGERGSLVTVASVEGLEGTAGGSSYNAAKGG VVLLTKNIALDYGPSGIRANVICPGFIETPMAHNVFSIPGMEAPLASITREHALQRLGRPEEIAAMAAFLLSTDASFVSG QAIAVDGGYTAGRDHGVVELFGFPS
Specific function: Part of the bacABCDE operon responsible for the biosynthesis of bacilysin [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=34.8484848484849, Blast_Score=130, Evalue=2e-30, Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=35.9683794466403, Blast_Score=119, Evalue=2e-27, Organism=Homo sapiens, GI83715985, Length=249, Percent_Identity=34.136546184739, Blast_Score=106, Evalue=3e-23, Organism=Homo sapiens, GI66933014, Length=230, Percent_Identity=27.3913043478261, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=30.952380952381, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI32483357, Length=263, Percent_Identity=28.8973384030418, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=29.7297297297297, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=30.9236947791165, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI59889578, Length=211, Percent_Identity=33.175355450237, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI126723750, Length=263, Percent_Identity=28.5171102661597, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI10190704, Length=275, Percent_Identity=29.0909090909091, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI31542939, Length=235, Percent_Identity=30.6382978723404, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=30.1204819277108, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI109715829, Length=251, Percent_Identity=27.8884462151394, Blast_Score=68, Evalue=1e-11, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=36.4705882352941, Blast_Score=127, Evalue=5e-31, Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=31.404958677686, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=32.2709163346614, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=29.2682926829268, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=27.4193548387097, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=32.6612903225806, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=31.3492063492063, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=27.2, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=30.4, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1789057, Length=202, Percent_Identity=30.1980198019802, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=30.3846153846154, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=22.9571984435798, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787526, Length=261, Percent_Identity=26.8199233716475, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1786701, Length=196, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=31.8548387096774, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=32.9365079365079, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=31.2, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=32.156862745098, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=27.9527559055118, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=30.1960784313725, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=24.8995983935743, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17561402, Length=265, Percent_Identity=27.9245283018868, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=26.5682656826568, Blast_Score=72, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=176, Percent_Identity=33.5227272727273, Blast_Score=72, Evalue=9e-14, Organism=Saccharomyces cerevisiae, GI6322861, Length=258, Percent_Identity=25.968992248062, Blast_Score=66, Evalue=5e-12, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=35.2226720647773, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=34.5528455284553, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=34.5238095238095, Blast_Score=116, Evalue=2e-26, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=32.520325203252, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI28571526, Length=261, Percent_Identity=31.4176245210728, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=31.1538461538462, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=30.4, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=29.1338582677165, Blast_Score=91, Evalue=7e-19, Organism=Drosophila melanogaster, GI24644337, Length=178, Percent_Identity=34.8314606741573, Blast_Score=87, Evalue=1e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 27019; Mature: 26888
Theoretical pI: Translated: 5.29; Mature: 5.29
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTGMVNPDRARSRTFVVTGAASGIGLATARRLLAEGGTVVGADLADPPGGLGPRFTFVPA CCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEEC DVTDESAVAAVLAAVPGRLDGVFHAAGVAGGGPVHLLDRAEWDRVIGVNLTGTFLVAKAA CCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHH LARMIDQSRVDGERGSLVTVASVEGLEGTAGGSSYNAAKGGVVLLTKNIALDYGPSGIRA HHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECEEEEECCCCCEE NVICPGFIETPMAHNVFSIPGMEAPLASITREHALQRLGRPEEIAAMAAFLLSTDASFVS EEECCCHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHC GQAIAVDGGYTAGRDHGVVELFGFPS CCEEEEECCCCCCCCCCEEEEECCCC >Mature Secondary Structure TGMVNPDRARSRTFVVTGAASGIGLATARRLLAEGGTVVGADLADPPGGLGPRFTFVPA CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEEC DVTDESAVAAVLAAVPGRLDGVFHAAGVAGGGPVHLLDRAEWDRVIGVNLTGTFLVAKAA CCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHH LARMIDQSRVDGERGSLVTVASVEGLEGTAGGSSYNAAKGGVVLLTKNIALDYGPSGIRA HHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECEEEEECCCCCEE NVICPGFIETPMAHNVFSIPGMEAPLASITREHALQRLGRPEEIAAMAAFLLSTDASFVS EEECCCHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHC GQAIAVDGGYTAGRDHGVVELFGFPS CCEEEEECCCCCCCCCCEEEEECCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA