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The map label for this gene is mcr

Identifier: 41408736

GI number: 41408736

Start: 2971676

End: 2972758

Strand: Reverse

Name: mcr

Synonym: MAP2638c

Alternate gene names: 41408736

Gene position: 2972758-2971676 (Counterclockwise)

Preceding gene: 41408738

Following gene: 41408735

Centisome position: 61.55

GC content: 71.47

Gene sequence:

>1083_bases
ATGGCTGGACCGTTGCAGGGACTGCGTGTTGTCGAGTTGTCCGGCATCGGGCCGGGCCCGCACGCCGCGATGATCCTGGG
GGACCTGGGCGCCGACGTGGTGCGCATCGACCGGCCATCCGGCGCCCCCGGCGGTGTCGTCAAGGACGCCATGAGCCGCA
ATCGCCGCATCGTCACCGCCGACCTGAAATCCGACCAGGGGCGCGAGCTCGTGCTCAAACTGGTCGCCAAGGCCGACGTG
CTGATCGAGGGCTACCGCCCGGGCGTCACCGAGCGGCTCGGCCTGGGCCCGCAGGACTGCGCCAAGGTCAACGACCGGCT
GATCTACGCCCGGATGACCGGCTGGGGGCAGACCGGCCCGCGCAGCCAGCAGGCCGGCCACGACATCAACTACATCTCGC
TGAACGGCATCCTGCACGCCATCGGCCGGGCGAACGAACGCCCCGTTCCGCCGCTGAACCTGGTCGGCGATTTCGGCGGC
GGCTCGATGTTCCTGCTGCTCGGCATCCTGTCCGCACTGTGGGAGCGGCAGAGCTCCGGCAAGGGCCAGGTCGTCGACGC
CGCCATGGTGGACGGCTCCAGCGTGCTGGTCCAGATGATGTGGCAGATGCGGGCCTCGGGGATGTGGACCGACGCGCGCG
GCACCAACCTGCTCGACGGCGGCGCGCCCTACTACGACACCTACGAGTGCGCCGACGGGCGCTACGTCGCGGTCGGCGCC
ATCGAGCCGCAGTTCTACGCGGCGATGCTGGCCGGGCTGGGCCTGGACGGTGCCGACCTGCCCGGGCAGAACGACGTCAG
CCGCTGGCCCGAGCTGCGCGCCGCGCTGACCGAGAAGTTCGCCAGCCGCGACCGCGACCACTGGGCCAAGGTGTTCGCCG
ACTCCGACGCCTGCGTGACGCCGGTGCTGGCCTTCGGCGAGGTGCAGACCGAGCCGCACATCACCGAGCGCAACACCTTC
TACGAGGTGGACGGGGGACTGCAGCCGCTGCCGGCGCCGCGGTTCTCCCGCACCGCCCCGCAGACGCCGCGCCCCGCGGC
GCCGGTGACCGACGCGACGGCCATACTCGACGAGTGGGTATAG

Upstream 100 bases:

>100_bases
GGGGTGCGCGGGCTTACGGCACGGCTGCGAAGATGTCGATCGACCGGTTGTTAGAGGCGAACGGTCGACGGCGTCAGAGC
GGACGAAAGGTCGATGGATC

Downstream 100 bases:

>100_bases
TCCCGACCAACCAGTTGGCTGGCTAGGGCTCGGGATTCGAAGGGAATTCAGGAAGGACTCGCATGGAGATCAAGGACGCC
GTCGCCGTTGTCACCGGGGG

Product: Mcr

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MAGPLQGLRVVELSGIGPGPHAAMILGDLGADVVRIDRPSGAPGGVVKDAMSRNRRIVTADLKSDQGRELVLKLVAKADV
LIEGYRPGVTERLGLGPQDCAKVNDRLIYARMTGWGQTGPRSQQAGHDINYISLNGILHAIGRANERPVPPLNLVGDFGG
GSMFLLLGILSALWERQSSGKGQVVDAAMVDGSSVLVQMMWQMRASGMWTDARGTNLLDGGAPYYDTYECADGRYVAVGA
IEPQFYAAMLAGLGLDGADLPGQNDVSRWPELRAALTEKFASRDRDHWAKVFADSDACVTPVLAFGEVQTEPHITERNTF
YEVDGGLQPLPAPRFSRTAPQTPRPAAPVTDATAILDEWV

Sequences:

>Translated_360_residues
MAGPLQGLRVVELSGIGPGPHAAMILGDLGADVVRIDRPSGAPGGVVKDAMSRNRRIVTADLKSDQGRELVLKLVAKADV
LIEGYRPGVTERLGLGPQDCAKVNDRLIYARMTGWGQTGPRSQQAGHDINYISLNGILHAIGRANERPVPPLNLVGDFGG
GSMFLLLGILSALWERQSSGKGQVVDAAMVDGSSVLVQMMWQMRASGMWTDARGTNLLDGGAPYYDTYECADGRYVAVGA
IEPQFYAAMLAGLGLDGADLPGQNDVSRWPELRAALTEKFASRDRDHWAKVFADSDACVTPVLAFGEVQTEPHITERNTF
YEVDGGLQPLPAPRFSRTAPQTPRPAAPVTDATAILDEWV
>Mature_359_residues
AGPLQGLRVVELSGIGPGPHAAMILGDLGADVVRIDRPSGAPGGVVKDAMSRNRRIVTADLKSDQGRELVLKLVAKADVL
IEGYRPGVTERLGLGPQDCAKVNDRLIYARMTGWGQTGPRSQQAGHDINYISLNGILHAIGRANERPVPPLNLVGDFGGG
SMFLLLGILSALWERQSSGKGQVVDAAMVDGSSVLVQMMWQMRASGMWTDARGTNLLDGGAPYYDTYECADGRYVAVGAI
EPQFYAAMLAGLGLDGADLPGQNDVSRWPELRAALTEKFASRDRDHWAKVFADSDACVTPVLAFGEVQTEPHITERNTFY
EVDGGLQPLPAPRFSRTAPQTPRPAAPVTDATAILDEWV

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI42794625, Length=358, Percent_Identity=45.2513966480447, Blast_Score=323, Evalue=2e-88,
Organism=Homo sapiens, GI266456254, Length=358, Percent_Identity=45.2513966480447, Blast_Score=322, Evalue=3e-88,
Organism=Homo sapiens, GI266458393, Length=250, Percent_Identity=50.4, Blast_Score=258, Evalue=4e-69,
Organism=Homo sapiens, GI266458397, Length=248, Percent_Identity=50, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI300863128, Length=374, Percent_Identity=27.807486631016, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI300863124, Length=336, Percent_Identity=28.2738095238095, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI266458395, Length=137, Percent_Identity=48.1751824817518, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI42822893, Length=137, Percent_Identity=48.1751824817518, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI300863126, Length=369, Percent_Identity=25.2032520325203, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI13376042, Length=336, Percent_Identity=24.702380952381, Blast_Score=98, Evalue=9e-21,
Organism=Escherichia coli, GI87082093, Length=369, Percent_Identity=25.2032520325203, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788717, Length=206, Percent_Identity=28.6407766990291, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786222, Length=336, Percent_Identity=26.1904761904762, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32564160, Length=336, Percent_Identity=36.9047619047619, Blast_Score=225, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI115535051, Length=327, Percent_Identity=37.6146788990826, Blast_Score=219, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24585488, Length=362, Percent_Identity=45.0276243093923, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24648431, Length=347, Percent_Identity=29.6829971181556, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 38573; Mature: 38442

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGPLQGLRVVELSGIGPGPHAAMILGDLGADVVRIDRPSGAPGGVVKDAMSRNRRIVTA
CCCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEE
DLKSDQGRELVLKLVAKADVLIEGYRPGVTERLGLGPQDCAKVNDRLIYARMTGWGQTGP
ECCCCCCHHHHHHHHHHHHHEEECCCCCCHHHHCCCHHHHHHHCCEEEEEEECCCCCCCC
RSQQAGHDINYISLNGILHAIGRANERPVPPLNLVGDFGGGSMFLLLGILSALWERQSSG
CCHHCCCCCCEEEHHHHHHHHCCCCCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHCCCC
KGQVVDAAMVDGSSVLVQMMWQMRASGMWTDARGTNLLDGGAPYYDTYECADGRYVAVGA
CCCEEEEEEECCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCEECCCCCEEEEEC
IEPQFYAAMLAGLGLDGADLPGQNDVSRWPELRAALTEKFASRDRDHWAKVFADSDACVT
CCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHH
PVLAFGEVQTEPHITERNTFYEVDGGLQPLPAPRFSRTAPQTPRPAAPVTDATAILDEWV
HHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
AGPLQGLRVVELSGIGPGPHAAMILGDLGADVVRIDRPSGAPGGVVKDAMSRNRRIVTA
CCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEE
DLKSDQGRELVLKLVAKADVLIEGYRPGVTERLGLGPQDCAKVNDRLIYARMTGWGQTGP
ECCCCCCHHHHHHHHHHHHHEEECCCCCCHHHHCCCHHHHHHHCCEEEEEEECCCCCCCC
RSQQAGHDINYISLNGILHAIGRANERPVPPLNLVGDFGGGSMFLLLGILSALWERQSSG
CCHHCCCCCCEEEHHHHHHHHCCCCCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHCCCC
KGQVVDAAMVDGSSVLVQMMWQMRASGMWTDARGTNLLDGGAPYYDTYECADGRYVAVGA
CCCEEEEEEECCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCEECCCCCEEEEEC
IEPQFYAAMLAGLGLDGADLPGQNDVSRWPELRAALTEKFASRDRDHWAKVFADSDACVT
CCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHH
PVLAFGEVQTEPHITERNTFYEVDGGLQPLPAPRFSRTAPQTPRPAAPVTDATAILDEWV
HHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]