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The map label for this gene is plsC [H]

Identifier: 41408397

GI number: 41408397

Start: 2576935

End: 2578008

Strand: Reverse

Name: plsC [H]

Synonym: MAP2299c

Alternate gene names: 41408397

Gene position: 2578008-2576935 (Counterclockwise)

Preceding gene: 41408398

Following gene: 41408396

Centisome position: 53.38

GC content: 69.37

Gene sequence:

>1074_bases
CTGCGGTTCAGCAGCCGCGGCCCGGTGGGTCTGCGGCGGCAGTTGCGCACCCTCGCCGGATTCGGGTCGATGTTCCCGGT
CGCGGCCGGTGCGGTGGGCGTCGGTGTGCTGACCCGCAACCGGCGCCGCGGCGTCAACTTCTTCACCTCCACGTTCTCCC
AGTTGTCGCTGGCCATCGCCGGGGTGCATCTCAACGTCATCGGCAAGGAGAACCTGACCGCCCAACGCCCCGCGGTCTTC
ATCTTCAACCACCGCAACCAGGTCGACCCGGTGATCGCCGGGGCGCTGGTGCGCGACAACTGGGTTGCGGTGGGCAAGAA
GGAACTCGAGAAGGACCCGGTGATGGGCACGCTGGGCAAGTTGCTGGACGGCGTGTTCATCGACCGCGACGACCCCGCCG
CCGCGGTGGAGACGCTGCACACGGTCGAAGACCGGGCCCGCAACGGCCTGTCGATCCTGATTGCCCCCGAGGGCACCCGG
GTCGACACCACCGAGGTCGGCCCATTCAAGAAGGGGCCCTTCAGGATTGCGATGGCCGCCGGGATCCCGATCGTGCCGAT
CGTGATCCGCAACGCCGAACTCGTCGCCGCCCGGAACTCGACCGTCATCAACCCCGGCACCGTCGACGTGGCCGTCTTTC
CGCCGATCTCGGTGCAGGACTGGACACTTGACACGCTGCCGGAGCGCATCGCCGAGGTGCGCCAGCTCTATCTGGACACC
CTGGCCAACTGGCCGGTCGGCGAACTGCCCGAGGTCGACCTGTACGCGGAGAAGAAAGCGGCGCAAAAGGCGCGCGGCCG
GGCCGCCAAAAGCCCCGCGACAAGCCCTGCCAAACCCCCCGCCAAGAGCCCCGCGAAACGCCCCGCCAAGAAATCGGCGG
CGAAGAAGACCGCGGCCACCTCGGCGGCCAAGACGCGCGCGAAAAAGACTGTGGTCGAACCGAAGTCGCGCACCACCCCG
GCCGCACCGAACCCGGAAGTCGCCGCGTCGCACAACGGGGAAGTGAGCCCCTCCCGCGCGGCCGACCCGATCGGCGCCGA
ACCACCCGAAGCGCCGCCCCGAGGGCGTCCGTGA

Upstream 100 bases:

>100_bases
TGACGAGGACGTCGCCCTGATGTATCTGGTCGGCAATCCGCGGCCGACCAATCCCGAGGGCAAGATGGCCGCCGTCGCCA
AGCGCCGCGGTTGGCCGATC

Downstream 100 bases:

>100_bases
CCGAACCGGCGGCAGACGCCAGCGCGCTGCTCACCGAACAAGACTCGCTGGTGTTGGCGTCCATGGCCTCTGCGGTCGAG
GTGGACCTGGTCACCGTCTG

Product: hypothetical protein

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRFSSRGPVGLRRQLRTLAGFGSMFPVAAGAVGVGVLTRNRRRGVNFFTSTFSQLSLAIAGVHLNVIGKENLTAQRPAVF
IFNHRNQVDPVIAGALVRDNWVAVGKKELEKDPVMGTLGKLLDGVFIDRDDPAAAVETLHTVEDRARNGLSILIAPEGTR
VDTTEVGPFKKGPFRIAMAAGIPIVPIVIRNAELVAARNSTVINPGTVDVAVFPPISVQDWTLDTLPERIAEVRQLYLDT
LANWPVGELPEVDLYAEKKAAQKARGRAAKSPATSPAKPPAKSPAKRPAKKSAAKKTAATSAAKTRAKKTVVEPKSRTTP
AAPNPEVAASHNGEVSPSRAADPIGAEPPEAPPRGRP

Sequences:

>Translated_357_residues
MRFSSRGPVGLRRQLRTLAGFGSMFPVAAGAVGVGVLTRNRRRGVNFFTSTFSQLSLAIAGVHLNVIGKENLTAQRPAVF
IFNHRNQVDPVIAGALVRDNWVAVGKKELEKDPVMGTLGKLLDGVFIDRDDPAAAVETLHTVEDRARNGLSILIAPEGTR
VDTTEVGPFKKGPFRIAMAAGIPIVPIVIRNAELVAARNSTVINPGTVDVAVFPPISVQDWTLDTLPERIAEVRQLYLDT
LANWPVGELPEVDLYAEKKAAQKARGRAAKSPATSPAKPPAKSPAKRPAKKSAAKKTAATSAAKTRAKKTVVEPKSRTTP
AAPNPEVAASHNGEVSPSRAADPIGAEPPEAPPRGRP
>Mature_357_residues
MRFSSRGPVGLRRQLRTLAGFGSMFPVAAGAVGVGVLTRNRRRGVNFFTSTFSQLSLAIAGVHLNVIGKENLTAQRPAVF
IFNHRNQVDPVIAGALVRDNWVAVGKKELEKDPVMGTLGKLLDGVFIDRDDPAAAVETLHTVEDRARNGLSILIAPEGTR
VDTTEVGPFKKGPFRIAMAAGIPIVPIVIRNAELVAARNSTVINPGTVDVAVFPPISVQDWTLDTLPERIAEVRQLYLDT
LANWPVGELPEVDLYAEKKAAQKARGRAAKSPATSPAKPPAKSPAKRPAKKSAAKKTAATSAAKTRAKKTVVEPKSRTTP
AAPNPEVAASHNGEVSPSRAADPIGAEPPEAPPRGRP

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI6041665, Length=173, Percent_Identity=28.9017341040462, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI5453718, Length=178, Percent_Identity=26.9662921348315, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI15100175, Length=178, Percent_Identity=26.9662921348315, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1789395, Length=160, Percent_Identity=35, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17564032, Length=170, Percent_Identity=31.1764705882353, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17568319, Length=180, Percent_Identity=27.2222222222222, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=206, Percent_Identity=32.0388349514563, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24641614, Length=200, Percent_Identity=28, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24641612, Length=200, Percent_Identity=28, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281364648, Length=229, Percent_Identity=26.6375545851528, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582856, Length=229, Percent_Identity=26.6375545851528, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582854, Length=229, Percent_Identity=26.6375545851528, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 37936; Mature: 37936

Theoretical pI: Translated: 11.06; Mature: 11.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFSSRGPVGLRRQLRTLAGFGSMFPVAAGAVGVGVLTRNRRRGVNFFTSTFSQLSLAIA
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHE
GVHLNVIGKENLTAQRPAVFIFNHRNQVDPVIAGALVRDNWVAVGKKELEKDPVMGTLGK
EEEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCEEECCHHHHHCCCHHHHHHH
LLDGVFIDRDDPAAAVETLHTVEDRARNGLSILIAPEGTRVDTTEVGPFKKGPFRIAMAA
HHCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEC
GIPIVPIVIRNAELVAARNSTVINPGTVDVAVFPPISVQDWTLDTLPERIAEVRQLYLDT
CCCEEEEEEECCEEEEECCCEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
LANWPVGELPEVDLYAEKKAAQKARGRAAKSPATSPAKPPAKSPAKRPAKKSAAKKTAAT
HCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SAAKTRAKKTVVEPKSRTTPAAPNPEVAASHNGEVSPSRAADPIGAEPPEAPPRGRP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRFSSRGPVGLRRQLRTLAGFGSMFPVAAGAVGVGVLTRNRRRGVNFFTSTFSQLSLAIA
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHE
GVHLNVIGKENLTAQRPAVFIFNHRNQVDPVIAGALVRDNWVAVGKKELEKDPVMGTLGK
EEEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCEEECCHHHHHCCCHHHHHHH
LLDGVFIDRDDPAAAVETLHTVEDRARNGLSILIAPEGTRVDTTEVGPFKKGPFRIAMAA
HHCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEC
GIPIVPIVIRNAELVAARNSTVINPGTVDVAVFPPISVQDWTLDTLPERIAEVRQLYLDT
CCCEEEEEEECCEEEEECCCEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
LANWPVGELPEVDLYAEKKAAQKARGRAAKSPATSPAKPPAKSPAKRPAKKSAAKKTAAT
HCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SAAKTRAKKTVVEPKSRTTPAAPNPEVAASHNGEVSPSRAADPIGAEPPEAPPRGRP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]