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The map label for this gene is plsB2

Identifier: 41408396

GI number: 41408396

Start: 2574584

End: 2576938

Strand: Reverse

Name: plsB2

Synonym: MAP2298c

Alternate gene names: 41408396

Gene position: 2576938-2574584 (Counterclockwise)

Preceding gene: 41408397

Following gene: 41408395

Centisome position: 53.36

GC content: 68.32

Gene sequence:

>2355_bases
GTGACCGAACCGGCGGCAGACGCCAGCGCGCTGCTCACCGAACAAGACTCGCTGGTGTTGGCGTCCATGGCCTCTGCGGT
CGAGGTGGACCTGGTCACCGTCTGGCTGGAGCAGCAGCGCGCCGGCCACCCGGGTGCGCAATTCGAGCTGGTCAAACTGC
CCGCGCTGGACGCGCCGCCGGCGGAGATGACCGCGCTGGCCGAGCGGCTCGAGGCCGGCGACGACCGCTCGGTGGTGCCG
GTGCGGGTGTTCTGGCTGCCGCCACCGGATCGCGGGCGAATCGCCAAGCTGGCCGGGCTGGTTCCCGGCCGTGACCCCTA
CCACCCCAACCAGCGTCTGCAAGCACAGATCCTGCGCCGCGCCCCGCAGCGGGCCCGGGTGGTGGCCGGTGAGGCGGCCA
CCGTCTCCGAACTGCGCCGCCAGTGGCGCGACACCACCGTCGGCGACGACCAGCGCGACTTCGCCCAATTCGTCATCCGC
CGCGCCATCTTGGCGATGGAGCGGGTCGAATACCGGATACTGGGACCGCAATACAAGTCGCCGCGGCTGGTGAAGCCGGA
GATCTTGGCGTCCAACAGGTTTCGAGCCGGGCTGGCCAAGATCCCGGGCGCCACCGTCGAGGAAGCCGGGAAGATGCTCG
ACGAGCTCGCCACCGGGTGGAGCCGGGCATCGGTCGATTTGGTCTCGGTGCTCGGCCGGTTGATCAGCCGCGGCTTCGAC
CGCGAGATCGACTACGACGAATACCAGGTGGCGGCGATGCGCACCGCCCTGGAAGCCCACCCCGCGGTGCTGCTGTTCTC
GCACCGGTCCTACATCGACGGCGCGGTGGTGCCGGTGGCCATGCAGGAGAACCGGTTACCGCCGGTGCACGTCTTCGCCG
GCATCAACCTGTCGTTCGGGGCGATGGGGCCGCTGCTGCGGCGCTCCGGTGTCATCTTCATCCGCCGCAACATCGGCAAC
GACCAGCTCTACAAGTACGTCCTGCGAGAATACGTCGGCTACATCGTCGAGAAGCGGTTCAACCTGAGCTGGTCCATCGA
GGGCACCCGCTCGCGCACCGGCAAGATGCTGCCGCCCAAACTCGGCCTGCTGTCCTACGTTGCCGACGCCTACCTGGATG
GCCGCAGCGAAGACATTCTGCTGCAACCGGTTTCGATCAGCTTCGATCAGCTGCACGAGACCGCGGAGTACGCCGCCTAC
GCCCGCGGTGGTGAGAAGACGCCCGAAGGCGTGGGCTGGCTGTACAACTTCATCCGGGCGCAGGGCGAACGCAACTACGG
CAAGATCTACGTCCGATTCCCCGAGGCCGTGTCGATGCGCCAATACCTGGGTGCGCCGCACGGCCCGCTGGCGCAGGACC
CCGACGCCAAACGCCTTGCGCTGCAGAAGATGTCCTTCGAAGTCGCCTGGCGGATCCTGCAGGCGACGCCGGTGACGGCG
ACCGGGCTGGTGTGCGCGCTGCTGCTGACCACCCGCGGCGCGGCGTTGACCCTGCGCCAACTGCATCACACCCTGCAGGA
CTCGCTGGATTACCTGGAACGCAAACAGAATCCGATGTCGACCAGTGCCCTGCGGCTGCGCTCGCCGGACGGTGTGCGGG
CGGCGGTGGACGCGCTGTCCAACGGGCACCCCGTCACTCGGATCGACGGCGGCCGGGAGCCGGTGTGGCAGATCACGCCC
GAACACCAGCACGCCGCGGCGTTCTACCGCAACTCGGTGATCCATGCCTTTCTGGAGACCTCCATCGTCGAACTGGCGCT
GGCACACGCCAAGCACGTCGACGGCGACCGCATGCAGGCCTTCTGGGACCAGGCGATGCGGCTGCGCGATCTGCTCAAGT
TCGACTTCTACTTCGCGGACTCGGCGACGTTCCGGGACAACATCGCCGAAGAGATGGCCTGGCACGACAATTGGGAGGAC
CACGTCGCCGCCGGCGGCGACGAGATCGACGCGCTGCTGTTCGCCAAGCGGCCGCTGATGGCCGAAGCGATGCTGCGGGT
GTTCTTCGAGGCCTACGAGATCGTCGCCGACGTGCTGCGCGACGCCCCGGCGGACATCGGGAACAAGGAACTGACGCGGC
TGGCCCTGGGGGTGGGCCGGCAGTATGTGGCACAAACCCGGATCCGCAGCAGCGAATCGGTGTCGACCCTGCTGTTCGCC
ACCGCGCGTCAGGTCGTCGAGGACCAGGACCTGATAGCGGCCGCGCCTGACCTGGCCGAACGACGGGACGCGTTCCTGCG
CGAGCTGCGCGCCATCCTGCGGGACTTCGACTACGTCGGCCGCGTCGCGCGCGAGCAGTTCGTGGCCCGGGAGGCCAAGG
CGCGCCGGGAGAGCCTGGACAGTCGACCGGGATAG

Upstream 100 bases:

>100_bases
ACCCGGAAGTCGCCGCGTCGCACAACGGGGAAGTGAGCCCCTCCCGCGCGGCCGACCCGATCGGCGCCGAACCACCCGAA
GCGCCGCCCCGAGGGCGTCC

Downstream 100 bases:

>100_bases
CCGACCGCCCCGCCAATACCCTGGGGGGATGACCGTCGCCCCGCCGGCCGGCACCGCCTCGACCGAGGCGGTCCCGCAGC
ACCGCACGCTGGTGTGGCCG

Product: glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: GPAT [H]

Number of amino acids: Translated: 784; Mature: 783

Protein sequence:

>784_residues
MTEPAADASALLTEQDSLVLASMASAVEVDLVTVWLEQQRAGHPGAQFELVKLPALDAPPAEMTALAERLEAGDDRSVVP
VRVFWLPPPDRGRIAKLAGLVPGRDPYHPNQRLQAQILRRAPQRARVVAGEAATVSELRRQWRDTTVGDDQRDFAQFVIR
RAILAMERVEYRILGPQYKSPRLVKPEILASNRFRAGLAKIPGATVEEAGKMLDELATGWSRASVDLVSVLGRLISRGFD
REIDYDEYQVAAMRTALEAHPAVLLFSHRSYIDGAVVPVAMQENRLPPVHVFAGINLSFGAMGPLLRRSGVIFIRRNIGN
DQLYKYVLREYVGYIVEKRFNLSWSIEGTRSRTGKMLPPKLGLLSYVADAYLDGRSEDILLQPVSISFDQLHETAEYAAY
ARGGEKTPEGVGWLYNFIRAQGERNYGKIYVRFPEAVSMRQYLGAPHGPLAQDPDAKRLALQKMSFEVAWRILQATPVTA
TGLVCALLLTTRGAALTLRQLHHTLQDSLDYLERKQNPMSTSALRLRSPDGVRAAVDALSNGHPVTRIDGGREPVWQITP
EHQHAAAFYRNSVIHAFLETSIVELALAHAKHVDGDRMQAFWDQAMRLRDLLKFDFYFADSATFRDNIAEEMAWHDNWED
HVAAGGDEIDALLFAKRPLMAEAMLRVFFEAYEIVADVLRDAPADIGNKELTRLALGVGRQYVAQTRIRSSESVSTLLFA
TARQVVEDQDLIAAAPDLAERRDAFLRELRAILRDFDYVGRVAREQFVAREAKARRESLDSRPG

Sequences:

>Translated_784_residues
MTEPAADASALLTEQDSLVLASMASAVEVDLVTVWLEQQRAGHPGAQFELVKLPALDAPPAEMTALAERLEAGDDRSVVP
VRVFWLPPPDRGRIAKLAGLVPGRDPYHPNQRLQAQILRRAPQRARVVAGEAATVSELRRQWRDTTVGDDQRDFAQFVIR
RAILAMERVEYRILGPQYKSPRLVKPEILASNRFRAGLAKIPGATVEEAGKMLDELATGWSRASVDLVSVLGRLISRGFD
REIDYDEYQVAAMRTALEAHPAVLLFSHRSYIDGAVVPVAMQENRLPPVHVFAGINLSFGAMGPLLRRSGVIFIRRNIGN
DQLYKYVLREYVGYIVEKRFNLSWSIEGTRSRTGKMLPPKLGLLSYVADAYLDGRSEDILLQPVSISFDQLHETAEYAAY
ARGGEKTPEGVGWLYNFIRAQGERNYGKIYVRFPEAVSMRQYLGAPHGPLAQDPDAKRLALQKMSFEVAWRILQATPVTA
TGLVCALLLTTRGAALTLRQLHHTLQDSLDYLERKQNPMSTSALRLRSPDGVRAAVDALSNGHPVTRIDGGREPVWQITP
EHQHAAAFYRNSVIHAFLETSIVELALAHAKHVDGDRMQAFWDQAMRLRDLLKFDFYFADSATFRDNIAEEMAWHDNWED
HVAAGGDEIDALLFAKRPLMAEAMLRVFFEAYEIVADVLRDAPADIGNKELTRLALGVGRQYVAQTRIRSSESVSTLLFA
TARQVVEDQDLIAAAPDLAERRDAFLRELRAILRDFDYVGRVAREQFVAREAKARRESLDSRPG
>Mature_783_residues
TEPAADASALLTEQDSLVLASMASAVEVDLVTVWLEQQRAGHPGAQFELVKLPALDAPPAEMTALAERLEAGDDRSVVPV
RVFWLPPPDRGRIAKLAGLVPGRDPYHPNQRLQAQILRRAPQRARVVAGEAATVSELRRQWRDTTVGDDQRDFAQFVIRR
AILAMERVEYRILGPQYKSPRLVKPEILASNRFRAGLAKIPGATVEEAGKMLDELATGWSRASVDLVSVLGRLISRGFDR
EIDYDEYQVAAMRTALEAHPAVLLFSHRSYIDGAVVPVAMQENRLPPVHVFAGINLSFGAMGPLLRRSGVIFIRRNIGND
QLYKYVLREYVGYIVEKRFNLSWSIEGTRSRTGKMLPPKLGLLSYVADAYLDGRSEDILLQPVSISFDQLHETAEYAAYA
RGGEKTPEGVGWLYNFIRAQGERNYGKIYVRFPEAVSMRQYLGAPHGPLAQDPDAKRLALQKMSFEVAWRILQATPVTAT
GLVCALLLTTRGAALTLRQLHHTLQDSLDYLERKQNPMSTSALRLRSPDGVRAAVDALSNGHPVTRIDGGREPVWQITPE
HQHAAAFYRNSVIHAFLETSIVELALAHAKHVDGDRMQAFWDQAMRLRDLLKFDFYFADSATFRDNIAEEMAWHDNWEDH
VAAGGDEIDALLFAKRPLMAEAMLRVFFEAYEIVADVLRDAPADIGNKELTRLALGVGRQYVAQTRIRSSESVSTLLFAT
ARQVVEDQDLIAAAPDLAERRDAFLRELRAILRDFDYVGRVAREQFVAREAKARRESLDSRPG

Specific function: De novo phospholipid biosynthesis; first step. [C]

COG id: COG2937

COG function: function code I; Glycerol-3-phosphate O-acyltransferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPAT/DAPAT family [H]

Homologues:

Organism=Homo sapiens, GI7657134, Length=539, Percent_Identity=25.7884972170686, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI190358539, Length=429, Percent_Identity=24.009324009324, Blast_Score=91, Evalue=4e-18,
Organism=Escherichia coli, GI87082362, Length=403, Percent_Identity=28.7841191066998, Blast_Score=145, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI25147672, Length=338, Percent_Identity=26.0355029585799, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71988723, Length=503, Percent_Identity=22.4652087475149, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71988728, Length=415, Percent_Identity=23.1325301204819, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17864692, Length=343, Percent_Identity=26.530612244898, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24650754, Length=376, Percent_Identity=28.1914893617021, Blast_Score=109, Evalue=7e-24,
Organism=Drosophila melanogaster, GI21357731, Length=376, Percent_Identity=28.1914893617021, Blast_Score=109, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24650752, Length=376, Percent_Identity=28.1914893617021, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR022284 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.15 [H]

Molecular weight: Translated: 87717; Mature: 87586

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPAADASALLTEQDSLVLASMASAVEVDLVTVWLEQQRAGHPGAQFELVKLPALDAPP
CCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCH
AEMTALAERLEAGDDRSVVPVRVFWLPPPDRGRIAKLAGLVPGRDPYHPNQRLQAQILRR
HHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHH
APQRARVVAGEAATVSELRRQWRDTTVGDDQRDFAQFVIRRAILAMERVEYRILGPQYKS
CCHHHHEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
PRLVKPEILASNRFRAGLAKIPGATVEEAGKMLDELATGWSRASVDLVSVLGRLISRGFD
CCCCCHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
REIDYDEYQVAAMRTALEAHPAVLLFSHRSYIDGAVVPVAMQENRLPPVHVFAGINLSFG
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCCCEEEEECCCCCHH
AMGPLLRRSGVIFIRRNIGNDQLYKYVLREYVGYIVEKRFNLSWSIEGTRSRTGKMLPPK
HHCHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCH
LGLLSYVADAYLDGRSEDILLQPVSISFDQLHETAEYAAYARGGEKTPEGVGWLYNFIRA
HHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
QGERNYGKIYVRFPEAVSMRQYLGAPHGPLAQDPDAKRLALQKMSFEVAWRILQATPVTA
CCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
TGLVCALLLTTRGAALTLRQLHHTLQDSLDYLERKQNPMSTSALRLRSPDGVRAAVDALS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHC
NGHPVTRIDGGREPVWQITPEHQHAAAFYRNSVIHAFLETSIVELALAHAKHVDGDRMQA
CCCCEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FWDQAMRLRDLLKFDFYFADSATFRDNIAEEMAWHDNWEDHVAAGGDEIDALLFAKRPLM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHCCCHH
AEAMLRVFFEAYEIVADVLRDAPADIGNKELTRLALGVGRQYVAQTRIRSSESVSTLLFA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TARQVVEDQDLIAAAPDLAERRDAFLRELRAILRDFDYVGRVAREQFVAREAKARRESLD
HHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRPG
CCCC
>Mature Secondary Structure 
TEPAADASALLTEQDSLVLASMASAVEVDLVTVWLEQQRAGHPGAQFELVKLPALDAPP
CCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCH
AEMTALAERLEAGDDRSVVPVRVFWLPPPDRGRIAKLAGLVPGRDPYHPNQRLQAQILRR
HHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHH
APQRARVVAGEAATVSELRRQWRDTTVGDDQRDFAQFVIRRAILAMERVEYRILGPQYKS
CCHHHHEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
PRLVKPEILASNRFRAGLAKIPGATVEEAGKMLDELATGWSRASVDLVSVLGRLISRGFD
CCCCCHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
REIDYDEYQVAAMRTALEAHPAVLLFSHRSYIDGAVVPVAMQENRLPPVHVFAGINLSFG
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCCCEEEEECCCCCHH
AMGPLLRRSGVIFIRRNIGNDQLYKYVLREYVGYIVEKRFNLSWSIEGTRSRTGKMLPPK
HHCHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCH
LGLLSYVADAYLDGRSEDILLQPVSISFDQLHETAEYAAYARGGEKTPEGVGWLYNFIRA
HHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
QGERNYGKIYVRFPEAVSMRQYLGAPHGPLAQDPDAKRLALQKMSFEVAWRILQATPVTA
CCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
TGLVCALLLTTRGAALTLRQLHHTLQDSLDYLERKQNPMSTSALRLRSPDGVRAAVDALS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHC
NGHPVTRIDGGREPVWQITPEHQHAAAFYRNSVIHAFLETSIVELALAHAKHVDGDRMQA
CCCCEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FWDQAMRLRDLLKFDFYFADSATFRDNIAEEMAWHDNWEDHVAAGGDEIDALLFAKRPLM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHCCCHH
AEAMLRVFFEAYEIVADVLRDAPADIGNKELTRLALGVGRQYVAQTRIRSSESVSTLLFA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TARQVVEDQDLIAAAPDLAERRDAFLRELRAILRDFDYVGRVAREQFVAREAKARRESLD
HHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRPG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA