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The map label for this gene is tig

Identifier: 41408380

GI number: 41408380

Start: 2551239

End: 2552633

Strand: Reverse

Name: tig

Synonym: MAP2282c

Alternate gene names: 41408380

Gene position: 2552633-2551239 (Counterclockwise)

Preceding gene: 41408382

Following gene: 41408379

Centisome position: 52.85

GC content: 69.25

Gene sequence:

>1395_bases
GTGAAGAGCACCGTCGAGCAGTTGAGCCCTACCCGGGTGCGCATCAACGTGGAGGTCCCCTTCGCCGAACTCGAGCCCGA
CTTCCAGCGGGCCTACAAGGAACTGGCCAAGCAGGTGCGGCTGCCCGGCTTCCGGCCCGGCAAGGCGCCGGCGAAGTTGC
TGGAGGCCCGCTTCGGCCGGGAGGCGATGCTCGACCAGGTCGTCACCGAGGCGCTGCCCGCCCGGTACGGACAGGCCGTG
GCCGAGTCGGAAGTGCACCCGCTGGGCCAGCCCGAGATCGAGGTCACCAAGAAGGAGTACGGGCAGGAGCTGGCCTTCAC
CGCCGAGGTCGACGTCCGCCCCGAGCTGAACCTGCCGGACCCGGGCGCCCTGAAGATCTCGGTGGACCCGATCGAGGTCA
CCGACGAGGACGTCGACGCCGAACTGCAGTCGCTGCGCGCCCGCTTCGGCACCCTGACCGGGGTGGAGCGCCCGGTGGCC
GAGGGGGACTTCGTCTCGATCGACCTGTCGGCCACCATCGACGGGCAGGAGGTGCCCGGCGCCACCGCCCAGGGGCTGTC
GCACGAGGTCGGCTCCGGCCGGCTCATCGAGGGGCTGGACGAGGCCCTGATCGGGATGTCCGTCGACGAATCCCGGGAGT
TCACCACCAAGCTGGTGTCGGGCGAGCACGCCGGCCAGGACGCCCAGGTGACGGTCACGGTCAAGTCGGTCAAGGAGCGC
GAGCTGCCCGAGCCCGACGACGAGTTCGCCCAACTGGCCAGCGAATTCGACACCATCGACGAGCTGCGGGCCAACCTGCG
CGAGCAGGTCGGCCGGGTCAAGCGGGCGCAGCAGGCCGAACGCATCCGCGACGCCGCGATCGACACCCTGCTCGAGCAGG
TCGACATCCCGTTGCCGGAAGCAATCGTCAAGGCCCAGGTGGACAGCGCCCTGCACGGCGCGCTGCACAGCCTCAACCAC
GACGAGTCCAAACTCGAGGAAGTGCTTGCCCAGCAAGGGAAGTCCCGCGAGGAGTTCGAGAACGAGACGCGCACCGCCGC
CGAGACGGACGTCAAGAAGCAGTTGTTGCTCGACGCACTGGCCGACAAGCTGCAGGTCCAGGTCGGCCAGGAAGACCTGA
CCGAGCGGCTGGTGGCGACCTCGCGGCAGTACGGCATCGAGCCGCAGCAGTTGCTGGCCTACCTTCAGGAGAACAACCAG
CTGCCGGCCATGTTCGCCGATGTGCGACGGGCGCTGGCCATCGCCGAGGTGATCCGGGCGGCGACGGTCACCGACACCGC
CGGCAACACCATCGACACCAGTGAGTTCTTCGGCAAGCGCCCGTCGGGCGACGGCGCCGCCGATGAGGACGCCGATCAGG
CCGACGAATCCACCACGGCCGACGCCGGCGAATGA

Upstream 100 bases:

>100_bases
GGCCGCAGGTTCAAATCCTGTCACCCCGACCAGCACGACCGGCCCCGTGCCCCGCGCACGGCCCACCGAGCGCCAGCAAC
GAGTACCGAGGAGCACACCC

Downstream 100 bases:

>100_bases
CCTTGCCGATGACGCTGTGAGCGAACGCGCCCCGTTTCCGGGGTGCGTGGCCGCGAAACGGCGGGCCCGGTTGGTTAGTG
TCGGTGCAGAGAAGAACTCG

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAPAKLLEARFGREAMLDQVVTEALPARYGQAV
AESEVHPLGQPEIEVTKKEYGQELAFTAEVDVRPELNLPDPGALKISVDPIEVTDEDVDAELQSLRARFGTLTGVERPVA
EGDFVSIDLSATIDGQEVPGATAQGLSHEVGSGRLIEGLDEALIGMSVDESREFTTKLVSGEHAGQDAQVTVTVKSVKER
ELPEPDDEFAQLASEFDTIDELRANLREQVGRVKRAQQAERIRDAAIDTLLEQVDIPLPEAIVKAQVDSALHGALHSLNH
DESKLEEVLAQQGKSREEFENETRTAAETDVKKQLLLDALADKLQVQVGQEDLTERLVATSRQYGIEPQQLLAYLQENNQ
LPAMFADVRRALAIAEVIRAATVTDTAGNTIDTSEFFGKRPSGDGAADEDADQADESTTADAGE

Sequences:

>Translated_464_residues
MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAPAKLLEARFGREAMLDQVVTEALPARYGQAV
AESEVHPLGQPEIEVTKKEYGQELAFTAEVDVRPELNLPDPGALKISVDPIEVTDEDVDAELQSLRARFGTLTGVERPVA
EGDFVSIDLSATIDGQEVPGATAQGLSHEVGSGRLIEGLDEALIGMSVDESREFTTKLVSGEHAGQDAQVTVTVKSVKER
ELPEPDDEFAQLASEFDTIDELRANLREQVGRVKRAQQAERIRDAAIDTLLEQVDIPLPEAIVKAQVDSALHGALHSLNH
DESKLEEVLAQQGKSREEFENETRTAAETDVKKQLLLDALADKLQVQVGQEDLTERLVATSRQYGIEPQQLLAYLQENNQ
LPAMFADVRRALAIAEVIRAATVTDTAGNTIDTSEFFGKRPSGDGAADEDADQADESTTADAGE
>Mature_464_residues
MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAPAKLLEARFGREAMLDQVVTEALPARYGQAV
AESEVHPLGQPEIEVTKKEYGQELAFTAEVDVRPELNLPDPGALKISVDPIEVTDEDVDAELQSLRARFGTLTGVERPVA
EGDFVSIDLSATIDGQEVPGATAQGLSHEVGSGRLIEGLDEALIGMSVDESREFTTKLVSGEHAGQDAQVTVTVKSVKER
ELPEPDDEFAQLASEFDTIDELRANLREQVGRVKRAQQAERIRDAAIDTLLEQVDIPLPEAIVKAQVDSALHGALHSLNH
DESKLEEVLAQQGKSREEFENETRTAAETDVKKQLLLDALADKLQVQVGQEDLTERLVATSRQYGIEPQQLLAYLQENNQ
LPAMFADVRRALAIAEVIRAATVTDTAGNTIDTSEFFGKRPSGDGAADEDADQADESTTADAGE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=347, Percent_Identity=28.5302593659942, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_MYCA1 (A0QDF1)

Other databases:

- EMBL:   CP000479
- RefSeq:   YP_880939.1
- ProteinModelPortal:   A0QDF1
- SMR:   A0QDF1
- STRING:   A0QDF1
- EnsemblBacteria:   EBMYCT00000012236
- GeneID:   4525872
- GenomeReviews:   CP000479_GR
- KEGG:   mav:MAV_1712
- TIGR:   MAV_1712
- eggNOG:   COG0544
- GeneTree:   EBGT00050000015814
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- PhylomeDB:   A0QDF1
- ProtClustDB:   PRK01490
- BioCyc:   MAVI243243:MAV_1712-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PANTHER:   PTHR10516
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 50651; Mature: 50651

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAPAKLLEARFGR
CCCCHHHCCCCEEEEEEECCHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCH
EAMLDQVVTEALPARYGQAVAESEVHPLGQPEIEVTKKEYGQELAFTAEVDVRPELNLPD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHCCCCEEEEEEEECCCCCCCCC
PGALKISVDPIEVTDEDVDAELQSLRARFGTLTGVERPVAEGDFVSIDLSATIDGQEVPG
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCC
ATAQGLSHEVGSGRLIEGLDEALIGMSVDESREFTTKLVSGEHAGQDAQVTVTVKSVKER
CHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHC
ELPEPDDEFAQLASEFDTIDELRANLREQVGRVKRAQQAERIRDAAIDTLLEQVDIPLPE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AIVKAQVDSALHGALHSLNHDESKLEEVLAQQGKSREEFENETRTAAETDVKKQLLLDAL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADKLQVQVGQEDLTERLVATSRQYGIEPQQLLAYLQENNQLPAMFADVRRALAIAEVIRA
HHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ATVTDTAGNTIDTSEFFGKRPSGDGAADEDADQADESTTADAGE
HHHCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAPAKLLEARFGR
CCCCHHHCCCCEEEEEEECCHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCH
EAMLDQVVTEALPARYGQAVAESEVHPLGQPEIEVTKKEYGQELAFTAEVDVRPELNLPD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHCCCCEEEEEEEECCCCCCCCC
PGALKISVDPIEVTDEDVDAELQSLRARFGTLTGVERPVAEGDFVSIDLSATIDGQEVPG
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCC
ATAQGLSHEVGSGRLIEGLDEALIGMSVDESREFTTKLVSGEHAGQDAQVTVTVKSVKER
CHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHC
ELPEPDDEFAQLASEFDTIDELRANLREQVGRVKRAQQAERIRDAAIDTLLEQVDIPLPE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AIVKAQVDSALHGALHSLNHDESKLEEVLAQQGKSREEFENETRTAAETDVKKQLLLDAL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADKLQVQVGQEDLTERLVATSRQYGIEPQQLLAYLQENNQLPAMFADVRRALAIAEVIRA
HHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ATVTDTAGNTIDTSEFFGKRPSGDGAADEDADQADESTTADAGE
HHHCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA