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The map label for this gene is cysQ_2

Identifier: 41408156

GI number: 41408156

Start: 2266817

End: 2267545

Strand: Reverse

Name: cysQ_2

Synonym: MAP2058c

Alternate gene names: 41408156

Gene position: 2267545-2266817 (Counterclockwise)

Preceding gene: 41408158

Following gene: 41408154

Centisome position: 46.95

GC content: 72.29

Gene sequence:

>729_bases
ATGAATGACCATGAGCTGGCCGCGCGGTTGGCCACCGAGGCCGGTCGGCTGCTGCTGGGGGTTCGAGACGAGTTCGCCGA
CGCTCCGGCAAGCGAGCGGAAAGCGGCGGGGGACAAGCGATCCCACGATTTTCTGATCGAGGCGCTGGCTGCCGAACGGC
CCGGCGATGCCGTGCTGTCCGAGGAGGGCGCCGACGACCCGGTGCGATTGCGCTCCGAGCGGGTCTGGATCGTCGACCCG
CTGGACGGCACGCGGGAGTTCTCCGAGCTCGGCCGCGACGACTGGGCGGTGCACGTCGCGCTCTGGGAGGCCGGCGAGCT
GGTGGCCGGCGCGGTGGCACTGCCGGCGCAGGGCGTCACGTTCGCGACCCCCGAGGTCGCGTCACCCCCCGTCGCGCCGG
GCAAGCCGCGCATCGTGGTGTCGCGCACCCGCCCGCCCGCCATCGCGTTGAACGTGCGGGACGCGTTGGACGGTGTTCTG
GTGGAAATGGGTTCGGCCGGCGCCAAGGTGGCCTCGGTCGTCCAGGGGCTCTCCGACGTGTACGTGCACGCCGGCGGCCA
GTTCGAATGGGACTCGGCCGCGCCCGTTGCGGTGGCGCGGGCCGCCGGATTGCACACGTCGCGCATCGACGGGTCGACGC
TGGCCTACAACCAACCCGACCCGAAGCTGCCCGATCTGGTGGTCTGCCGTCCCGAGCTGGCCGACGCCGTCCTCGCGGTC
ACCCGCTGA

Upstream 100 bases:

>100_bases
CACCAGATTACGGGGCGAAAATCGGGTCTAGGGCGGTCCACGCCGACGGGGAATCAAAGGGTAAAGTTGGTCATCGCTAC
CAACATATTGAGGATTTCGC

Downstream 100 bases:

>100_bases
CGGTCCTCGAGAGTCGCTGGCGCGCTTGGTCTTTCGCGCTAGGACGCGGGCCTGGGCAATGGCCGCGACTCTGCACTCAG
AGCAGCGCCTGCTGCCAGGA

Product: CysQ_2

Products: NA

Alternate protein names: PAP phosphatase; 3'(2'),5'-bisphosphate nucleotidase; 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; D-fructose-1,6-bisphosphate 1-phosphohydrolase; DPNPase; Fructose-1,6-bisphosphatase; FBPase; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNDHELAARLATEAGRLLLGVRDEFADAPASERKAAGDKRSHDFLIEALAAERPGDAVLSEEGADDPVRLRSERVWIVDP
LDGTREFSELGRDDWAVHVALWEAGELVAGAVALPAQGVTFATPEVASPPVAPGKPRIVVSRTRPPAIALNVRDALDGVL
VEMGSAGAKVASVVQGLSDVYVHAGGQFEWDSAAPVAVARAAGLHTSRIDGSTLAYNQPDPKLPDLVVCRPELADAVLAV
TR

Sequences:

>Translated_242_residues
MNDHELAARLATEAGRLLLGVRDEFADAPASERKAAGDKRSHDFLIEALAAERPGDAVLSEEGADDPVRLRSERVWIVDP
LDGTREFSELGRDDWAVHVALWEAGELVAGAVALPAQGVTFATPEVASPPVAPGKPRIVVSRTRPPAIALNVRDALDGVL
VEMGSAGAKVASVVQGLSDVYVHAGGQFEWDSAAPVAVARAAGLHTSRIDGSTLAYNQPDPKLPDLVVCRPELADAVLAV
TR
>Mature_242_residues
MNDHELAARLATEAGRLLLGVRDEFADAPASERKAAGDKRSHDFLIEALAAERPGDAVLSEEGADDPVRLRSERVWIVDP
LDGTREFSELGRDDWAVHVALWEAGELVAGAVALPAQGVTFATPEVASPPVAPGKPRIVVSRTRPPAIALNVRDALDGVL
VEMGSAGAKVASVVQGLSDVYVHAGGQFEWDSAAPVAVARAAGLHTSRIDGSTLAYNQPDPKLPDLVVCRPELADAVLAV
TR

Specific function: Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can ser

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Localized On The Inner Face Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7; =3.1.3.11; =3.1.3.25 [H]

Molecular weight: Translated: 25484; Mature: 25484

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDHELAARLATEAGRLLLGVRDEFADAPASERKAAGDKRSHDFLIEALAAERPGDAVLS
CCHHHHHHHHHHHCCCEEEEECHHHCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCEEC
EEGADDPVRLRSERVWIVDPLDGTREFSELGRDDWAVHVALWEAGELVAGAVALPAQGVT
CCCCCCCEEECCCEEEEECCCCCHHHHHHCCCCCEEEEEEEECCCCHHHHHEECCCCCCE
FATPEVASPPVAPGKPRIVVSRTRPPAIALNVRDALDGVLVEMGSAGAKVASVVQGLSDV
EECCCCCCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHE
YVHAGGQFEWDSAAPVAVARAAGLHTSRIDGSTLAYNQPDPKLPDLVVCRPELADAVLAV
EEECCCEECCCCCCCHHHHHHCCCCCCCCCCCEEECCCCCCCCCCEEEECHHHHHHHHHC
TR
CC
>Mature Secondary Structure
MNDHELAARLATEAGRLLLGVRDEFADAPASERKAAGDKRSHDFLIEALAAERPGDAVLS
CCHHHHHHHHHHHCCCEEEEECHHHCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCEEC
EEGADDPVRLRSERVWIVDPLDGTREFSELGRDDWAVHVALWEAGELVAGAVALPAQGVT
CCCCCCCEEECCCEEEEECCCCCHHHHHHCCCCCEEEEEEEECCCCHHHHHEECCCCCCE
FATPEVASPPVAPGKPRIVVSRTRPPAIALNVRDALDGVLVEMGSAGAKVASVVQGLSDV
EECCCCCCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHE
YVHAGGQFEWDSAAPVAVARAAGLHTSRIDGSTLAYNQPDPKLPDLVVCRPELADAVLAV
EEECCCEECCCCCCCHHHHHHCCCCCCCCCCCEEECCCCCCCCCCEEEECHHHHHHHHHC
TR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]