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The map label for this gene is hapE [H]

Identifier: 41407718

GI number: 41407718

Start: 1774270

End: 1776285

Strand: Direct

Name: hapE [H]

Synonym: MAP1620

Alternate gene names: 41407718

Gene position: 1774270-1776285 (Clockwise)

Preceding gene: 41407717

Following gene: 41407719

Centisome position: 36.74

GC content: 65.92

Gene sequence:

>2016_bases
TTGGGGCTACGGGACCATCACCTATCCGACCATTACCTATCCGACCATCGAGAGGACATCGGCTTGATGCGCAGCCGCTA
CGCCGGCGAACCGTTCACCACCTCCACGGCCGAGATCGCCGCCGCCCTCGAGGATGTCAGCATCCCGACGCTGTTGCTCT
CGCTCGTCCACATCACCGGCGACCCACGCTTCATCCGCGACTTCAAGCAGATGGGCATCTTCCTCAACGAGGTCCAGGGG
TTCATGTCCGAGGAGGACAAGGCCCGGGCCCGCGCCGAGGCGCTCTCGGTCATCACCGACTACCGCGACCGCGGTTGCCC
CGAACCCGAGCCGCTCAGCCCCGAGCTCATCCGGGAAATGATGGACTGGGCCGCCTGCGAACACGTGCCCGACGACTACC
TACCGCTGATCTGCGAAGAGCTGGACCTCGACGGCGTCGACCCGCGCCGCCCCGCCGCCTTGCCGGCCGAACGCGCGGCC
GGGCTCCCGGTGCTCGTCGTCGGCTGCGGCGAATCCGGCATCCTGGCCGGCGTCCGCCTCAAGCAGGCCAACATTCCGTT
CACCATCGTCGAGAAGAACGCCGGCCCGGGCGGAACATGGTGGGAGAACAGCTATCCCGGCGCCCGGGTGGACGTGGCCA
ACCATTTCTATTGCTACAGCTTCGAACCCAACAACGACTGGACCCATTTCTTCGCCGAGCAATACGAGCTGCAGGACTAC
TTCACCAAGGTCATCGACCAACACGACCTGGCCGGCCAGGTGCGCTGGCAGAGCGAGGTGCTCGCGGCCGAATGGGACGA
CGGCGACGGCACCTGGACGGTGTCGCTGCGCTCGGCCGACGGCCACACCGAAACAATGCGGGCGCGGGCGCTCATCACCG
CGGTGGGACAGCTGAACCGGCCCAACATCCCGGCCTTCGACGGCGCGCAGACCTTCCGGGGCCCGTCGTTCCATTCGGCG
GCCTGGGATCACTCGGTGGAGCTGAAGGGCAAGCGGGTTGCTCTCGTCGGCGCCGGCGCCAGCGGATTTCAGATCGCACC
GGCGATCGCCGCGGACGTCAAGCGGCTCACCGTGTTCCAGCGGACCGCGCAGTGGATGTTCCCCAACCCGATGTATCACG
ACGAGGTCGGCGACGGAGTGCGCTGGGCGATGCGCCATCTGCCGTTCTACGGCCGGTGGTATCGCTTCCTGGTGTTGTGG
CCCGGCTCCGACAAGGGCCTGGACGCTGCCGAGGCCGACCCGAACTACGCCGACCAGGAGCACGCCGTCAGCGACGTCAA
CGCCGCCGCCCACCTGATGTTCTCGCAATGGATCACCAGCCAGGTCGGCGAGGATTCGGAGTTGCTGGCCAAGGTGATGC
CCGACTATCCCGCCTGCGGTAAAAGGACCCTGCAGGACAACGGCAGTTGGCTGCGCACCCTGCAGCGCGACAACGTCGAA
CTGGTGCGCACGCCCATCGACAAGATCACGCCGCACGGCATCGTCACCGTCGACGGCGCGGCGTACGACGCCGATGTCAT
CGTGTACGCCACCGGATTCCGGCACACCGATGTGCTGTGGCCCCTGAAGGTGACCGGCCGCAACGGGGTCGACCTGCACC
AAATGTGGGGGAGCCGGCCGTATGCCTACCTGGGCATCACCGTGCCGGAATTCCCGAACTTCTTCATCATCTACGGCCCG
GGAACTCACCTCGCCCACGGCGGCAGCCTGATCTTCCAGTCCGAGCTGCAGATGCGCTACATCGACCAATGCCTGGCGCG
GCTGTGCGAGCCCGGTGTGCATTCCATCGAACCGAAACCCGACGCCGCCATCGATTGGCACCGGCGCACCCCAGGCCCAG
ATCAAGAAGATGGTGTGGTCGCACCCGGCGGTCAAGCACTCCTATTTCAAGAACGCCGACGGCGAGATTCACACGGTGAG
CCCATGGCGTCTCAACGAGTACTGGTCCGCGGTGCGCGAGCCCGATTGGTCGCAGTTCATGGTGCGGACGAACGATGCTG
TGCCACAAGGAAATAG

Upstream 100 bases:

>100_bases
CGTCCGACGCCCCCGACGACCCGCAACCGCCGATCCCTTGATCCGGCGCCGAGCGACCGGGTAGCGTAGTGCTGCAATTA
CGAAACTATGCGTAGCGTAA

Downstream 100 bases:

>100_bases
ATAGGGAAAGCGATAAGGAAAGTGAGCGCGACACTATGCGCACCGTAGTCGTCGACGGGCCCCGCAGCATCCGGGTGGAC
ACCCGCCCCGATCCCGTGCT

Product: hypothetical protein

Products: NA

Alternate protein names: HAPMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MGLRDHHLSDHYLSDHREDIGLMRSRYAGEPFTTSTAEIAAALEDVSIPTLLLSLVHITGDPRFIRDFKQMGIFLNEVQG
FMSEEDKARARAEALSVITDYRDRGCPEPEPLSPELIREMMDWAACEHVPDDYLPLICEELDLDGVDPRRPAALPAERAA
GLPVLVVGCGESGILAGVRLKQANIPFTIVEKNAGPGGTWWENSYPGARVDVANHFYCYSFEPNNDWTHFFAEQYELQDY
FTKVIDQHDLAGQVRWQSEVLAAEWDDGDGTWTVSLRSADGHTETMRARALITAVGQLNRPNIPAFDGAQTFRGPSFHSA
AWDHSVELKGKRVALVGAGASGFQIAPAIAADVKRLTVFQRTAQWMFPNPMYHDEVGDGVRWAMRHLPFYGRWYRFLVLW
PGSDKGLDAAEADPNYADQEHAVSDVNAAAHLMFSQWITSQVGEDSELLAKVMPDYPACGKRTLQDNGSWLRTLQRDNVE
LVRTPIDKITPHGIVTVDGAAYDADVIVYATGFRHTDVLWPLKVTGRNGVDLHQMWGSRPYAYLGITVPEFPNFFIIYGP
GTHLAHGGSLIFQSELQMRYIDQCLARLCEPGVHSIEPKPDAAIDWHRRTPGPDQEDGVVAPGGQALLFQERRRRDSHGE
PMASQRVLVRGARARLVAVHGADERCCATRK

Sequences:

>Translated_671_residues
MGLRDHHLSDHYLSDHREDIGLMRSRYAGEPFTTSTAEIAAALEDVSIPTLLLSLVHITGDPRFIRDFKQMGIFLNEVQG
FMSEEDKARARAEALSVITDYRDRGCPEPEPLSPELIREMMDWAACEHVPDDYLPLICEELDLDGVDPRRPAALPAERAA
GLPVLVVGCGESGILAGVRLKQANIPFTIVEKNAGPGGTWWENSYPGARVDVANHFYCYSFEPNNDWTHFFAEQYELQDY
FTKVIDQHDLAGQVRWQSEVLAAEWDDGDGTWTVSLRSADGHTETMRARALITAVGQLNRPNIPAFDGAQTFRGPSFHSA
AWDHSVELKGKRVALVGAGASGFQIAPAIAADVKRLTVFQRTAQWMFPNPMYHDEVGDGVRWAMRHLPFYGRWYRFLVLW
PGSDKGLDAAEADPNYADQEHAVSDVNAAAHLMFSQWITSQVGEDSELLAKVMPDYPACGKRTLQDNGSWLRTLQRDNVE
LVRTPIDKITPHGIVTVDGAAYDADVIVYATGFRHTDVLWPLKVTGRNGVDLHQMWGSRPYAYLGITVPEFPNFFIIYGP
GTHLAHGGSLIFQSELQMRYIDQCLARLCEPGVHSIEPKPDAAIDWHRRTPGPDQEDGVVAPGGQALLFQERRRRDSHGE
PMASQRVLVRGARARLVAVHGADERCCATRK
>Mature_670_residues
GLRDHHLSDHYLSDHREDIGLMRSRYAGEPFTTSTAEIAAALEDVSIPTLLLSLVHITGDPRFIRDFKQMGIFLNEVQGF
MSEEDKARARAEALSVITDYRDRGCPEPEPLSPELIREMMDWAACEHVPDDYLPLICEELDLDGVDPRRPAALPAERAAG
LPVLVVGCGESGILAGVRLKQANIPFTIVEKNAGPGGTWWENSYPGARVDVANHFYCYSFEPNNDWTHFFAEQYELQDYF
TKVIDQHDLAGQVRWQSEVLAAEWDDGDGTWTVSLRSADGHTETMRARALITAVGQLNRPNIPAFDGAQTFRGPSFHSAA
WDHSVELKGKRVALVGAGASGFQIAPAIAADVKRLTVFQRTAQWMFPNPMYHDEVGDGVRWAMRHLPFYGRWYRFLVLWP
GSDKGLDAAEADPNYADQEHAVSDVNAAAHLMFSQWITSQVGEDSELLAKVMPDYPACGKRTLQDNGSWLRTLQRDNVEL
VRTPIDKITPHGIVTVDGAAYDADVIVYATGFRHTDVLWPLKVTGRNGVDLHQMWGSRPYAYLGITVPEFPNFFIIYGPG
THLAHGGSLIFQSELQMRYIDQCLARLCEPGVHSIEPKPDAAIDWHRRTPGPDQEDGVVAPGGQALLFQERRRRDSHGEP
MASQRVLVRGARARLVAVHGADERCCATRK

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Can oxidize a wide range of acetophenone derivatives. Highest activity occurs with co

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=217, Percent_Identity=25.3456221198157, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.84 [H]

Molecular weight: Translated: 74860; Mature: 74729

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLRDHHLSDHYLSDHREDIGLMRSRYAGEPFTTSTAEIAAALEDVSIPTLLLSLVHITG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCC
DPRFIRDFKQMGIFLNEVQGFMSEEDKARARAEALSVITDYRDRGCPEPEPLSPELIREM
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
MDWAACEHVPDDYLPLICEELDLDGVDPRRPAALPAERAAGLPVLVVGCGESGILAGVRL
HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCEEEEEE
KQANIPFTIVEKNAGPGGTWWENSYPGARVDVANHFYCYSFEPNNDWTHFFAEQYELQDY
EECCCCEEEEECCCCCCCCCCCCCCCCCEEEECCEEEEEEECCCCCHHHHHHHHHHHHHH
FTKVIDQHDLAGQVRWQSEVLAAEWDDGDGTWTVSLRSADGHTETMRARALITAVGQLNR
HHHHHCCCCCCCCEEECCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC
PNIPAFDGAQTFRGPSFHSAAWDHSVELKGKRVALVGAGASGFQIAPAIAADVKRLTVFQ
CCCCCCCCCHHCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCEECHHHHHHHHHHHHHH
RTAQWMFPNPMYHDEVGDGVRWAMRHLPFYGRWYRFLVLWPGSDKGLDAAEADPNYADQE
HHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHH
HAVSDVNAAAHLMFSQWITSQVGEDSELLAKVMPDYPACGKRTLQDNGSWLRTLQRDNVE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHCCEE
LVRTPIDKITPHGIVTVDGAAYDADVIVYATGFRHTDVLWPLKVTGRNGVDLHQMWGSRP
EEECCHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCHHHHHCCCC
YAYLGITVPEFPNFFIIYGPGTHLAHGGSLIFQSELQMRYIDQCLARLCEPGVHSIEPKP
EEEEEEECCCCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DAAIDWHRRTPGPDQEDGVVAPGGQALLFQERRRRDSHGEPMASQRVLVRGARARLVAVH
CCCEECCCCCCCCCCCCCEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEE
GADERCCATRK
CCCCCHHCCCC
>Mature Secondary Structure 
GLRDHHLSDHYLSDHREDIGLMRSRYAGEPFTTSTAEIAAALEDVSIPTLLLSLVHITG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCC
DPRFIRDFKQMGIFLNEVQGFMSEEDKARARAEALSVITDYRDRGCPEPEPLSPELIREM
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
MDWAACEHVPDDYLPLICEELDLDGVDPRRPAALPAERAAGLPVLVVGCGESGILAGVRL
HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCEEEEEE
KQANIPFTIVEKNAGPGGTWWENSYPGARVDVANHFYCYSFEPNNDWTHFFAEQYELQDY
EECCCCEEEEECCCCCCCCCCCCCCCCCEEEECCEEEEEEECCCCCHHHHHHHHHHHHHH
FTKVIDQHDLAGQVRWQSEVLAAEWDDGDGTWTVSLRSADGHTETMRARALITAVGQLNR
HHHHHCCCCCCCCEEECCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC
PNIPAFDGAQTFRGPSFHSAAWDHSVELKGKRVALVGAGASGFQIAPAIAADVKRLTVFQ
CCCCCCCCCHHCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCEECHHHHHHHHHHHHHH
RTAQWMFPNPMYHDEVGDGVRWAMRHLPFYGRWYRFLVLWPGSDKGLDAAEADPNYADQE
HHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHH
HAVSDVNAAAHLMFSQWITSQVGEDSELLAKVMPDYPACGKRTLQDNGSWLRTLQRDNVE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHCCEE
LVRTPIDKITPHGIVTVDGAAYDADVIVYATGFRHTDVLWPLKVTGRNGVDLHQMWGSRP
EEECCHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCHHHHHCCCC
YAYLGITVPEFPNFFIIYGPGTHLAHGGSLIFQSELQMRYIDQCLARLCEPGVHSIEPKP
EEEEEEECCCCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DAAIDWHRRTPGPDQEDGVVAPGGQALLFQERRRRDSHGEPMASQRVLVRGARARLVAVH
CCCEECCCCCCCCCCCCCEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEE
GADERCCATRK
CCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11322873 [H]