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The map label for this gene is ybdR [H]

Identifier: 41407719

GI number: 41407719

Start: 1776321

End: 1777346

Strand: Direct

Name: ybdR [H]

Synonym: MAP1621

Alternate gene names: 41407719

Gene position: 1776321-1777346 (Clockwise)

Preceding gene: 41407718

Following gene: 41407722

Centisome position: 36.78

GC content: 71.54

Gene sequence:

>1026_bases
ATGCGCACCGTAGTCGTCGACGGGCCCCGCAGCATCCGGGTGGACACCCGCCCCGATCCCGTGCTTCCCGGGCCCGACGG
GGCGATCGTCGAGGTGAGCGCGGCCGGTATCTGCGGATCCGACCTGCACTTCTACGAGGCCGACTTCCCGATGCCGGACC
CGATTGCGCTGGGCCACGAGGCGATCGGCACCGTGGTGGAGGCCGGGCCGCAGGTGCGCAACGTCAAGGTCGGCGATCAG
GTCATGGTGTCCTCGGTCGCCGGCTGCGGCAGCTGCGCTGGCTGCGCCACCCGGGATCCGGTGCTGTGCCACTCCGGTTT
CCAGATCTTCGGGGGTGGTGTGCTGGGCGGCGCGCAGGCCGATCTGCTGGCGGTGCCCGCGGCCGACTTCCAGCTGCTGA
AGATCCCCGAGGGCATCAGCACCGAGCAGGCGCTGCTGCTCACCGACAATCTGGCCACCGGCTGGGCCGCCGCGCAGCGG
GCCGACATTCCCTTCGGTGGCACGGTGGCGGTCATCGGGCTGGGCGCGGTTGGCTTGTGCGCGCTGCGCAGCGCGCTGTT
CCAGGGCGCGGCAACGGTTTTCGCGGTCGATCAGGTTGACGGCCGGCTGGCGCGTGCCGCCCGGTGGGGGGCGACGCCCG
TCAAGGCGCCGGCGCTCGAGGCGATCCTCGCGGCCACCGGCGGCCGCGGCGCCGACGCGGTGATCGACGCCGTCGCCACG
GACGCCTCCCTGACCGAGGCGCTCAACGCGGTGCGGCCGGGCGGCACGGTCTCGGTGGTCGGCGTGCACGACATGAACCC
GTTCCCGCTCAACGCGCTGGGCTGCCTGATTCGCAGCATCACCCTGCGGATGACCACGGCGCCGGTGCAGCGCACCTGGC
CGGAACTGATTCCGCTGTTGCAGTCAGGCCGGCTGGACGTCGACGGAATCTTCACCACGACAATGCCTTTGGACGAGGCG
GCCATCGGGTATGCGACCGCGGGGTCGCGGTCGGGCGACGACGTCAAGATCCTGCTGAAACCGTAG

Upstream 100 bases:

>100_bases
GTGCGCGAGCCCGATTGGTCGCAGTTCATGGTGCGGACGAACGATGCTGTGCCACAAGGAAATAGATAGGGAAAGCGATA
AGGAAAGTGAGCGCGACACT

Downstream 100 bases:

>100_bases
CGGTGTTCACCGGGCCGCGGTGATGTACTGCGACCGCATGAAGCCGTCGATCTTGACGTCCACCTCCGGCGGCGTCATGC
CGTAACCGGCTTGCAGATCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MRTVVVDGPRSIRVDTRPDPVLPGPDGAIVEVSAAGICGSDLHFYEADFPMPDPIALGHEAIGTVVEAGPQVRNVKVGDQ
VMVSSVAGCGSCAGCATRDPVLCHSGFQIFGGGVLGGAQADLLAVPAADFQLLKIPEGISTEQALLLTDNLATGWAAAQR
ADIPFGGTVAVIGLGAVGLCALRSALFQGAATVFAVDQVDGRLARAARWGATPVKAPALEAILAATGGRGADAVIDAVAT
DASLTEALNAVRPGGTVSVVGVHDMNPFPLNALGCLIRSITLRMTTAPVQRTWPELIPLLQSGRLDVDGIFTTTMPLDEA
AIGYATAGSRSGDDVKILLKP

Sequences:

>Translated_341_residues
MRTVVVDGPRSIRVDTRPDPVLPGPDGAIVEVSAAGICGSDLHFYEADFPMPDPIALGHEAIGTVVEAGPQVRNVKVGDQ
VMVSSVAGCGSCAGCATRDPVLCHSGFQIFGGGVLGGAQADLLAVPAADFQLLKIPEGISTEQALLLTDNLATGWAAAQR
ADIPFGGTVAVIGLGAVGLCALRSALFQGAATVFAVDQVDGRLARAARWGATPVKAPALEAILAATGGRGADAVIDAVAT
DASLTEALNAVRPGGTVSVVGVHDMNPFPLNALGCLIRSITLRMTTAPVQRTWPELIPLLQSGRLDVDGIFTTTMPLDEA
AIGYATAGSRSGDDVKILLKP
>Mature_341_residues
MRTVVVDGPRSIRVDTRPDPVLPGPDGAIVEVSAAGICGSDLHFYEADFPMPDPIALGHEAIGTVVEAGPQVRNVKVGDQ
VMVSSVAGCGSCAGCATRDPVLCHSGFQIFGGGVLGGAQADLLAVPAADFQLLKIPEGISTEQALLLTDNLATGWAAAQR
ADIPFGGTVAVIGLGAVGLCALRSALFQGAATVFAVDQVDGRLARAARWGATPVKAPALEAILAATGGRGADAVIDAVAT
DASLTEALNAVRPGGTVSVVGVHDMNPFPLNALGCLIRSITLRMTTAPVQRTWPELIPLLQSGRLDVDGIFTTTMPLDEA
AIGYATAGSRSGDDVKILLKP

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=360, Percent_Identity=28.8888888888889, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI262073058, Length=348, Percent_Identity=24.4252873563218, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI71743840, Length=348, Percent_Identity=24.4252873563218, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI156523966, Length=341, Percent_Identity=26.3929618768328, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI71565154, Length=354, Percent_Identity=25.9887005649718, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4501939, Length=321, Percent_Identity=26.791277258567, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1786825, Length=389, Percent_Identity=33.6760925449871, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1788073, Length=345, Percent_Identity=28.9855072463768, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082125, Length=278, Percent_Identity=29.136690647482, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788075, Length=325, Percent_Identity=28.9230769230769, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790045, Length=334, Percent_Identity=29.0419161676647, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI226510992, Length=267, Percent_Identity=30.7116104868914, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787863, Length=351, Percent_Identity=25.3561253561254, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87081918, Length=267, Percent_Identity=31.8352059925094, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790718, Length=298, Percent_Identity=24.1610738255034, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788407, Length=275, Percent_Identity=25.0909090909091, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786552, Length=343, Percent_Identity=25.6559766763848, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=350, Percent_Identity=29.1428571428571, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17562878, Length=350, Percent_Identity=28.2857142857143, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562584, Length=306, Percent_Identity=25.8169934640523, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71988145, Length=279, Percent_Identity=27.5985663082437, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565904, Length=269, Percent_Identity=26.0223048327138, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25146526, Length=267, Percent_Identity=26.9662921348315, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997431, Length=266, Percent_Identity=26.6917293233083, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=362, Percent_Identity=29.2817679558011, Blast_Score=116, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6319955, Length=362, Percent_Identity=29.2817679558011, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6323099, Length=354, Percent_Identity=25.7062146892655, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6319258, Length=362, Percent_Identity=25.6906077348066, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319257, Length=344, Percent_Identity=25.8720930232558, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320033, Length=383, Percent_Identity=26.1096605744125, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=289, Percent_Identity=28.3737024221453, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=281, Percent_Identity=28.1138790035587, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=270, Percent_Identity=28.1481481481481, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=285, Percent_Identity=27.3684210526316, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17137530, Length=348, Percent_Identity=28.1609195402299, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17737897, Length=351, Percent_Identity=27.6353276353276, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17737895, Length=352, Percent_Identity=25.5681818181818, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI45550770, Length=339, Percent_Identity=27.7286135693215, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45551930, Length=339, Percent_Identity=27.7286135693215, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221457811, Length=339, Percent_Identity=27.7286135693215, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 34759; Mature: 34759

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVVVDGPRSIRVDTRPDPVLPGPDGAIVEVSAAGICGSDLHFYEADFPMPDPIALGHE
CCEEEECCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCHHCCHH
AIGTVVEAGPQVRNVKVGDQVMVSSVAGCGSCAGCATRDPVLCHSGFQIFGGGVLGGAQA
HHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCEEEECCCEEECCEEECCCCC
DLLAVPAADFQLLKIPEGISTEQALLLTDNLATGWAAAQRADIPFGGTVAVIGLGAVGLC
CEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHCCCCCCCCEEEEEHHHHHHHH
ALRSALFQGAATVFAVDQVDGRLARAARWGATPVKAPALEAILAATGGRGADAVIDAVAT
HHHHHHHHCCEEEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHC
DASLTEALNAVRPGGTVSVVGVHDMNPFPLNALGCLIRSITLRMTTAPVQRTWPELIPLL
CHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHH
QSGRLDVDGIFTTTMPLDEAAIGYATAGSRSGDDVKILLKP
HCCCCCCCEEEEECCCCCHHHCCEEECCCCCCCCEEEEECC
>Mature Secondary Structure
MRTVVVDGPRSIRVDTRPDPVLPGPDGAIVEVSAAGICGSDLHFYEADFPMPDPIALGHE
CCEEEECCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCHHCCHH
AIGTVVEAGPQVRNVKVGDQVMVSSVAGCGSCAGCATRDPVLCHSGFQIFGGGVLGGAQA
HHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCEEEECCCEEECCEEECCCCC
DLLAVPAADFQLLKIPEGISTEQALLLTDNLATGWAAAQRADIPFGGTVAVIGLGAVGLC
CEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHCCCCCCCCEEEEEHHHHHHHH
ALRSALFQGAATVFAVDQVDGRLARAARWGATPVKAPALEAILAATGGRGADAVIDAVAT
HHHHHHHHCCEEEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHC
DASLTEALNAVRPGGTVSVVGVHDMNPFPLNALGCLIRSITLRMTTAPVQRTWPELIPLL
CHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHH
QSGRLDVDGIFTTTMPLDEAAIGYATAGSRSGDDVKILLKP
HCCCCCCCEEEEECCCCCHHHCCEEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]